Professional Documents
Culture Documents
BURNS
Complications
Infection
Hypovolemia
Gastric ulcer
Acute renal failure
Infection
In patients with major burn injuries, infection
remains the major cause of death.
specific deficits in neutrophil chemotaxis,
phagocytosis, and intracellular bacterial killing.
decreased lymphocyte activation
reduction in immunoglobulin synthesis
The epidermis of the skin
becomes damaged
an ideal
environment for
microbial growth
Hypovolemia
from the liberation of
Burn injury injured vasoactive
area materials
promotes fluid
and protein increases the
Hypovolemi loss into the capillary
a extravascular permeability
compartment
peripheral and
compromise in- splanchnic
organ perfusion vasoconstriction
Bad Mucosal
blood flow
“Erosion of the stomach lining and duodenum
has been demonstrated in 86% of major burn
patients within 72 h of injury, with more than
40% of patients having gastrointestinal
bleeding”
Czaja A, McAlhany JC, Pruitt BA. Acute gastroduodenal disease after thermal
injury: an endoscopic evalution of incidence and natural history. N Engl J
Med 29: 925-29
Acute Renal failure
Diminished blood
burn injury volume and
cardiac output
Elevated levels
catecholamines, decrease in renal
angiotensin, blood
aldosterone and flow and glomerular
vasopressin filtration rate
acute renal
failure damage nefron
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