Professional Documents
Culture Documents
Childhood
Autistic Rett’s
Disintegrative
Disorder Disorder
Disorder
PDD-
Asperger’s
Not Otherwise
Disorder
Specified
http://www.dsm5.org/ProposedRevision
s/Pages/proposedrevision.aspx?rid=94
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Alex 18 Months
Diagnosed with Autism
First Year of Intervention
Prevalence
Terminology
Incidence: the number of new cases of disease in a
defined group of people over a specific time
Prevalence: the number of existing disease cases in a
defined group of people during a specific time period
Prevalence of ASD has continued to increase since
first survey in 1966 – why?
Increases in requests for service
Changes in diagnostic criteria
Increased assessment opportunities
Better awareness by pediatricians, teachers, parents
An actual increase in cases?
CDC Statistics
The prevalence was much lower (3.3 per 1,000) in Alabama and
higher (10.6 per 1,000) in New Jersey in 2002. (About 1 in 94)
Prevalence stayed the same from 2000 to 2002 in four of the six
sites with data for both years.
It rose slightly in Georgia and significantly in West Virginia,
indicating the need for tracking prevalence over time.
New Prevalence Rates
http://www.nytimes.com/2009/12/19/
health/19autism.html
http://www.cdc.gov/ncbddd/autism/in
dex.html
Current Prevalence Rates
Nationwide
One in 110 children is estimated to have
autism spectrum disorders nationwide.
In Missouri:
934 students diagnosed in 1997
5,777 students in 2009
Increased assessment
opportunities
Better awareness by
pediatricians, teachers, parents
An actual increase in cases?
Ideally, what does the
diagnostic process look like?
Assess all characteristics/abilities
3 major areas, adaptive behavior, IQ
Assess in multiple ways with multiple sources
Interview, observation, checklist/rating scales
Parent, teacher, professional examiner
Assess over time with multiple observations in
multiple settings
Home, school, daycare
Structured, unstructured
Clinical vs. Educational Diagnosis
Clinical diagnosis: conducted by psychologist,
neurologist, neuropsychologist
Without a clinical diagnosis, a child may still qualify for
special ed services according to federal and state autism
disability definition
Educational diagnosis: conducted by school
personnel, usually a team, consisting of people who
are familiar with the child.
Definition of Autism drawn from the Individuals with
Disabilities Education Act (IDEA)
Federal law which regulates eligibility, assessment, and
intervention of educational services for children with
disabilities
IDEA definition of Autism
•A developmental disability significantly affecting verbal and
nonverbal communication and social interaction, generally
evident before age 3, that adversely affects a child's
educational performance.
•Other characteristics often associated with autism are
engagement in repetitive activities and stereotyped
movements, resistance to environmental change or change in
daily routines, and unusual responses to sensory experiences.
•The term does not apply if a child's educational performance
is adversely affected primarily because the child has a
serious emotional disturbance as defined below.
Videos
Initial theory
Autism considered an emotional
disturbance inherited from parents
Kanner (1943): “inborn autistic
disturbances of affective contact”
No empirical support
Etiology: Psychodynamic Theory
Serotonin
Some studies have found higher levels in
children with ASD
Opioids
Display properties similar to morphine
Administration can result in stereotypy,
insensitivity to pain, reduced socialization
Some studies have found higher levels in
children with ASD
Etiology: Vaccines
http://scienceblogs.com/insolence/2
010/08/penn_teller_deconstruct_th
e_anti-vaccine.php
Warning!!!!
Etiology: Vaccines
Vaccines
Thimerosal - Preservative used in MMR vaccine used to contain
mercury
Wakefield et al. (1998)
Evidence for link b/w behavior changes and MMR was based on
report
Correlational study only
Ethical Problems
Financial and scientific conflicts that Dr. Wakefield did not
reveal in his paper.
For instance, part of the costs of Dr. Wakefield’s research were
paid by lawyers for parents seeking to sue vaccine makers for
damages.
Dr. Wakefield was also found to have patented in 1997 a
measles vaccine that would succeed if the combined vaccine were
withdrawn or discredited.
Etiology: Vaccines
In 2004, 10 of the 13 authors on the Wakefield
et al. study published an article in the same
journal (The Lancet) retracting the conclusions
made in the original article
http://www.childrensimmunisation.com/images/upload
ed/Docs/times_21-02-2004.pdf
http://www.oregon.gov/DHS/ph/acd/flu/public/FluM
MRautism.pdf
In 2010, the Lancet retracted the study
altogether
http://www.nytimes.com/2010/02/03/health/resear
ch/03lancet.html
Etiology: Vaccines
CDC - Vaccines
http://www.cdc.gov/ncbddd/autism/vaccines.htm
ASAT – summary of the vaccine controversy
http://www.asatonline.org/pdf/newsletter_preview.pdf
Videos
What Causes Autism?
http://www.autismspeaks.org/video/index.php
February (2009) court case
http://www.cnn.com/2009/HEALTH/02/11/autism.v
accines/index.html#cnnSTCVideo
So…what’s the cause of autism?
No one cause of autism has been identified
Genetic influences are likely most important
risk factor
But not only cause (MZ twin concordance < 100%)
Cause is likely multifactorial
Physiology and environment are ALWAYS
interacting from day 1
May be several types of autism with different
causes