Professional Documents
Culture Documents
Diseases
Infectios diseases
- Encompassesthewaysandmeansoftransmissionofinfectiousagenttothe
susceptiblehost arteries
- Optimumenvironment
TERMS
1. Contagious-disease that are spread directly transmitted from one person to
another. E.g. SARS
2. Infectious-are those disease not transmitted by ordinary contact but
require direct inoculation through a break in the continuity of the mucous
membrane. All contagious disease are infectious
3. Infection-an invasion of the body by pathogenic organism
Types of Infections
1.Local-limitedtospecificsite.
2.Focal-localinfectionthatorganismcanspreadto otherparts(Toothabscess).
3.Systemic-involvesthewholebody(typhoidfever)
a.recurrent-aninfectionthatrecurperiodically
b.Reinfection-secondaryinfectionwithsameorganism
c.superinfection-usuallyoccursduringantimicrobialtx foranotherinfection
d.autoinfection-infectionthatisalreadypresentand developingtoanotherpartofthebody
e.Acuteinfection-developsrapidly
f.Chronicinfection-slowly,mildlybutlonger
g.Bacteremia
h.Septicemia
i.Toxemia
j.viremia
4.Carrier-apersonwhoisharboringtheinfectiousagentbutdoesnotpresentclinicalsignsandsymptoms
5.Contact-personwhohavebeenexposedtodisease
6.Contamination-aprocessbywhichsomethingrendereduncleanorunsterile.
7.Isolation-separationofpatientwithCDfromotherpersonssothattransmissionoftosusceptible
personsisprevented
8.Reverseisolation-separationofsusceptiblepersonfromcontacttopatientswithCD
9.Quarantine-limitationofmovementofpersonwhichhavebeenexposedtoCD,foraperiodoftime
longerthanthelongestusualincubationperiodoftheCDtowhichtheyareexposed.
TypesofQuarantine
a.complete-acompletelimitationorfreedomof movementofthepersonhasbeenexposedto
CDtohaveeffectivepreventionofcontactto thosewhoarenotexposed.
b.Modified-selectivepartiallimitationoffreedom ofmovement.Ex.Exclusionofchildrenin
school.
c.surveillance-closesupervisionofcontactswithout restrictionsofmovement.
d.segregation-separationforspecialconsideration, controlorobservationofsomepartofthe
groupofpersonsfromtheothertofacilitate thecontrolofsomeCD.
10.Pathogenicity-abilitytoproducedisease
11.Virulence-therelativedamagebypathogens
Course of Infectious Process
1. Incubation period-from the entry of organism into the body until the onset of
signs and symptoms. Pathogens begins active replication.
-salmonella-6-24hrs
-Hepatitis B 50-180 days
-HIV months to years
2. Prodromal-period from non-specific signs and symptoms to the appearance
specific signs and symptoms
3. Illness/invasion/acute stage-the period from which a patient experience
maximum impact of illness. Specific signs and symptoms develop and become
evident.
4. Convalescent/defervescent-characterized by containment of infection,
progressive elimination of pathogen, repair of damage tissue and resolution of
symptoms
5. Resolution-is the total elimination of a pathogen from the body without residual
signs and symptoms.
ETIOLOGIC/INFECTIOUSAGENT:
Bacteria,virus,fungi
SUSCEPTIBLEHOST:elderly,children, RESERVOIR
chronicallyill,trauma (SOURCE):humans,animals,objects,
plants,environment
PORTALOFENTRY:mucous PORTALOFEXIT:respiratory
membrane,nonintactskin,GI, secretions,blood,stool,
GUT,respiratorytract
MODEOFSPREAD:contact,
vehicle,respiratory,vectorborne
1. ETIOLOGIC/INFECTIOUS AGENTS
-Invading microorganism capable of producing the disease
-Can be bacteria, virus, fungi, parasites
-The ability of the infectious agent to produce a disease depends on its
pathogenicity, virulence, invasiveness and specificity.
a. Bacteria-canselfreproduceandproducetoxinsthatareharmful
b. Virus-obligateintracellularparasite
c. Fungus-plantlikeorganismthatgrowsassinglecells
d. Protozoans-simplestorganismofplantkingdom
e. Rickettsiae-parasitesthatdependonlivingorganismforgrowth.
2. RESERVOIR:
-Antibody mediated
immunity
-Involves B lymphocyte (B
cells)
Figure14.9
CONDITION THAT WEAKENS THE PERSON’S DEFENSE
1. Poorhygiene
2. Malnutrition
3. Extremeages
4. Climate
5. Inadequatephysicalbarriers
6. Inheritedandacquiredimmunedeficiencies
7. Emotionalandphysicalstressors
8. Chronicdisease
9. Medicalandsurgicaltreatments
10. Inadequateimmunizations
HERD IMMUNITY
-Intactskinandmucousmembrane
-Ciliaofrespiratorytract.
CHEMICALBARRIERS:
-Gastricjuice,bodyfluids
-Interferons
WBC-bothnaturalandacquiredimmuneresponse
-Releaseschemicalmediatorshistamine,bradykininandprostaglandins
GRANULOCYTES:
-Neutrophil-phagocytic,basophilandeosinophil
AGRANULOCYTES:
-monocyte-phagocyticmacrophages
-Lymphocyte-TcellsandBcells-inhumoralandcellmediatedimmunity.
Figure14.16
II. Acquired immunity
- immunoglobulinfunctionsasantibodies,
antigenbindingproteinsthatare
presentonthesurfaceofBcelland
secretedbyplasmacells.
1.Bcells–transformedintoplasmacells.
Plasmacellsaretheoneresponsiblefor
theproductionofantibodies.
IMMUNOGLOBULIN ISOTYPES
a. IgG-most abundant, 80% of total serumIg, major roles in blood borne and
tissue infections, activates complement, crosses the placenta.
b. IgA-10-15%, found in bodily secretion like breast milk, saliva, tears, GIT and
respiratory and GUT, passes to neonate in breast milk for protection.
c.IgM-5-10%oftotalserumIg,firstimmunoglobulinproducedinprimaryimmuneresponse.ThefirstIg
synthesizedbyneonate
-Mostlyintravascularserum
-FirstIgproducedinresponsetobacterialandviralinfections
-Goodactivatorofcomplementbecauseofitssize
d. IgE-mediates hypersensitivity response like hay, wheal and flare, fever ,
asthma and anaphylactic shock
-Appears inserum
-Combats parasitic infestations
e. IgD-unknown function
-Appears inserum insmall amounts
-Possibly influences B lymphocytes function becauseit is the firstIgpresent in the
surface of Bcell
Figure14.12
T LYMPHOCYTE
-For cellular immunity
a. Helper T cells-are activated upon recognition of antigens and stimulate the rest of
the immune system
-secretes cytokine that attracts and activates B cells,cytotoxicT cells, natural killer
cells, macrophages, and other cells of the immune system.
b. CytotoxicT cells-attacks the antigens directly by altering the cell membrane and
causing cell lysisand releasing cytolyticenzymes and cytokines.
C Suppressor T cell-terminate the normal immune response
d. Memory T cells-responsible for recognizing the antigens
Figure14.10
4 MAIN TYPES OF ANTIGEN PREPARARTION
1. Toxoids-soluble exotoxinsof bacteria, such as diphtheria and tetanus, which
have been modified and rendered less toxicbyaddition of formalin or gentle
heating
2. Killed-cultured organism that are killed by heat. Usually at 60°C for 1 hr, UV,
chemicals like phenol, alcohol or formalin. Whooping cough, polio, cholera
3. Antigens isolated from infectious agents( subunits vaccines)
4. Attenuated live vaccine-these are made from strains that have lost their
virulence by growth culture. BCG, cowpox, OPV
UNIVERSAL PRECAUTION( UNIVERSAL BLOOD AND BODY FLUIDS
PRECAUTIONS)
-Are apply to those body fluids associated with blood borne pathogens namely:
HepB, HepC, HIV
- this includes blood and body fluids containing visible blood
-Blood, vaginal secretion, seminal fluid, CSF, synovial fluid, pleural fluid, pericardial
fluid, peritoneal fluid, amniotic fluid, saliva in dental procedures, body fluids
contaminated with blood, body fluids in situations where it is difficult to
differentiate among body fluids
UNIVERSAL PRECAUTIONS
1. Wear mask and protective eyewear in situations where droplets of blood or
body fluids may spray onto the membranes of the eye, mouth or nose
2. Wear gloves when in contact with blood or other body fluids containing blood
and when handling supplies and equipment or surfaces soiled with blood or
other body fluid. Change gloves after client contact.
3. Wear gowns in situations where it is likely that droplets of blood or fluids will be
sprayed.
4. Immediately and thoroughly wash hands or other skin surfaces that come in
contact with blood or other body fluids
5. To prevent needle stick injuries, deposit it into puncture resistant container
that has secure lids. Do not recap, break or bend needles after use
6. Use mouthpieces, resuscitation bags, or other ventilatory equipment when
providing resuscitation
7. Do not provide direct client care when you have open or exudativeskin lesions
STANDARD PRECAUTIONS:
- All patients regardless of diagnosis or presumed infection
- Are the primary strategy for reducing the risk of and controlling nosocomial
infections
-The disease climax occurs 2 3 days after the rash appears and is
marked by a temperature (39.4 to 40.6°C severe cough,
rhinorrhea, and puffy red
-About 5 days after the rash other symptoms disappear and
communicability ends.
S/Sx:•Complications:severeinfectionmayleadtosecondarybacterialinfectionandtoautoimmune
reactionororganinvasionbythevirus,resultinginotitismedia,pneumonia,andencephalitis.
a.preeruptive-feverhighgrade(3-4day)highlycommunicable,3C'sCoryza,conjunctivitis,coughand
photophobia,Koplik'sspot
Koplik'sspotsareliketiny,bluishgrayspeckssurroundedbyaredhalo.Theyappearontheoralmucosa
Oppositethemolarandoccasionallybleed.
Samsonline--transverselineoftheinflammation alongthemarginoftheeyelid.
b.eruptive—rashes,maculopapularrashes,reddish andblotchy(painful)"morbiliformrash"
firstappearonthehairlinebehinddieears— cephalocaudaldistributionentire
bodyis completelycoveredwithrashes
Whentherashreachesthefeet(2-3days later)itbeginstofadeinthesamesequenced
Itappeared.
c.posteruptive--eventuallyrushesbecomesbrown•brannydesquamation"-Asevereformknown
as"blackmeasles"—withhemorrhagicrashes,epistaxis,melenaandmarkedtoxicitymayoccur.
Diagnosis:
•koplik—distinctclinicalfeatures
•labtestfordifferential,causesomemildmeaslesmayresemblerubella,roseolainfantum,
toxoplasmosisandetc.
•Ifnecessary,measlesvirusmaybeisolatedfromtheblood,nasopharyngealsecretionsduringthe
febrileperiod.Serumantibodieswillappearwithindaysafteronsetoftherashandreachpeak
titers2—4weekslater.
Management:
I.Bedrest
2.Reliefofsymptoms
3.Immediateisolationthroughoutcommunicableperiod
4.Vaporizersandwarmenvironmenthelpreducerespiratoryirritation.
5.Observeforcomplicationslikepneumonia
6.Explainproceedingsonproperdisposalofdischarges.
7.Teachconcurrentandterminaldisinfection
NursingCare:
I.ProtecteyesofpatientfromglareofstronglightastheyapttoBeinflamed2.properventilation
3.Spongebath
4.Increasefluidintake
5.Sunglasses
6.Outofschoolforatleast4daysaltertherashappears,
Prevention:vaccine
Complications:
severe infection may lead to secondary bacterial infection and to autoimmune
reaction or organ invasion by the virus, resulting in otitismedia, pneumonia,
encephalitis (SSPE)
GERMANMEASLES(Rubella.Rotheln,Roseola,3daymeasles)Isanacute,mildlycontagiousviral
diseasesthatproducesadistinctive3-dayrashandlymphadenopathy
Commonamongchildrenages5—9,adolescentsandyoungadult.Thediseaseisself-limitingthe
prognosisisexcellent.
Etiology:Rubellavirus—atogavirus
SourceofInfection:Contactwithblood.urine,stools.nasopharyngealsecretionsandarticlesofinfected
persons,Transplacentaltransmission,especiallyinthefirsttrimesterofpregnancy,cancauseserious
birthdefect
-Humansaretheonlyknownhost
PeriodofCommunicability:10daysbeforetherashappearsuntil5later.IncubationPeriod:14—21days
S/SX
Prognosis:deathishighestinthefirsttwoyearsoflife.Inchildren,aftertheincubationperiod,rash
appearsabruptly.Inadolescentsandadults,prodromalsymptomssuchusheadache,anorexia,malaise,
lowgradefever,coryza.lymphadenopathyandsometimesconjunctivitisappearsfirst.Suboccipilal,
postauricular,andpostcervicallymhnodeenlargementisthehallmarksign.
-Rubellarashstartsattheface
-Thismaculopapulareruptionsspreadsrapidlyoftencoveringthetrunkandextremitieswithinhours
-Forscheimer'sspotmayprecedeoraccompanytherash.Forscheimerspotsaresmall,red,petechial
maculesonthesoftpalate.
Bytheendofthesecondday,thefacialrashesbegintofade,buttherashonthetrunkmaybeconfluent
andbemistakenforscarletfever.
-Therashcontinueslo,fadedownwardorderinwhichitappeared.
-Rashgenerallydisappearsonthe3rdday(sometimes4-5)sometimeswithcoryzaandconjunctivitis.
-Therapidappearanceandrapiddisappearanceoftherubellarashdistinguishesitfromrubeola
-Rubellacanoccurwithoutarashbutthisisrare
-Others:Lowgradefever,malaise,headache,mildconjunctivitis,sorethroat,stiffnessoftheneckand
anorexia.Splenomegaly,Testicularpain
-Complicationsarerarebutwhentheydo,theyoftenappearashemorrhagicproblemsuchas
thrombocytopenia.encephalitis,sinusitisorotitismedia.Youngwomensometimesexperiencesarthritis
Clinical Mnifestation:
a. Rash
b. fever less than 100°F
c. lymphadenopathy
d. Cold like symptoms usually accompanies the disease in the form of Cough.
congestion and coryza
e. forscheimersspot
Diagnosis:
-Therubellarash,lymphadenopathyandhistoryofexposurepermitsclinicaldiagnosisvidiomlabtest.
Cellculture,blood,urine.andc/f—confirmatory
- Convalescentserumthatshowsafourfoldriseinantibodytiters,confirmsthediagnosis.
Prevention:
a.immunizationbylive—virusinjection
Management:
-Rubella rash is self-limiting and only mildly pruritic, it doesn't require topical
or systemic medications.
-Purely symptomatic, treatment consists of aspirin for fever and joint pain.
-Bed rest isn't necessary but the patient should be isolated until the rash
disappears.
Congenital Rubella
-Growth retardation and congenital heart disease. (microcephaly, congenital
cataract, deaf and mute)
Measles German Measles
Fever before lesion High grade with skin Low grade before skin
rashes rashes
-Within24hourstherashtypicallybeginsassmallcropsofsmall,erythematousmaculesonthe
TRUNKorscalpthatprogressestopapulesandthenclearvesiclesonanerythematousbase."dewdrop
onarosepetal"
-Thevesiclesbecomecloudyandbreakseasilythenscabsform.therashspreadstothefaceandto
theextremities.
-Newvesiclescontinuetoappearfor3-4dayssotherashcontainsacombinationofredpapules,
vesicles,andscabsinvariousstages.
-Allstagesarepresentsimultaneouslybeforeallcoveredwithscabs."celestialmap“
-Congenitalvaricellacauseshypoplasticdeformity.scarringofthelimb,retardedgrowthandCNSand
eyemanifestation.Severeprurituswiththisrashmayprovokepersistentscratching,whichcanleadto
infection.cellulitis,furuncles,impetigo.
- Rarecomplications:pneumonia,reye'ssyndrome(fulminatingencephalitis)
Incubationperiod:
-2-3weeks.commonly13to17days.
PeriodofCommunicability:
• notmorethanonedaybeforeandmorethan6daysafterappearanceofthefirstcropofvesicles.
SusceptibilityandResistanceandOccurrence:
a.Universalamongthosenotpreviouslyattacked.Conferslongimmunity.
b.Secondattacksarerare.
c.Notcommoninearlyinfancy
Prevention:
a.Caseover15yearsoldshouldbeinvestigatedtoeliminatepossibilityofsmallpox.
b.Reportingtolocalauthority
c.Isolation
d.Concurrentdisinfectionofthroatandnosedischarges
e.Exclusionfromschoolfor1weekaftereruptionfirstappearsandavoidcontactwithsusceptible.
Treatment:
• Symptomatic
• Strictisolation
• Localorsystemicantipruritic
• Coolbicarbonateofsodabaths
• Calaminelotion
• Antihistamine
• Antibioticsifbacterialinfectiondevelops
• SalicylatesarecontraindicatedbecauseoftheirlinkwithReye's
• Acycloviritmayslowvesicleformation,andcontrolsystemicspreadofinfection
• VZIgmayprovidepassiveimmunity,lessensseverityifexposed
• Liveattenuated
Diagnosis:
Clinicalsigns
Doesnotrequirelaboratory,tests
Prevention:
-Good hygiene
-Don't scratch the lesions
-Trim the linger nails or tic mittens on his hands
-Report signs of complications , severe skin burning or secondary infection
Prognosis: Excellent
SMALL POX (variola) eradicated 1981
Etiology : Poxyvirusvariola
Three major forms
1. variolamajor (classic small pox) -contagious from onset until after the last scab was
shed.
2. variolaminor -a mild form that occurred in non vaccinated people and resulted
from a less virulent strain
3. varioloid-mild variant of small pox that occurred in previously vaccinated people
who had only partial immunity.
MOT:
• directly by respiratory droplets or dried scales of virus containing lesions a
Indirectly through contaminated linens or other objects. Period of
Communicability:
Incubation Period: 10 -14 days
ClinicalManifestation:
• aftertheincubationperiod;
• abruptonsetofchills(possibleseizuresinchildren)
• highfever40C
• headache
• backache
• severemalaise
• vomiting
• prostration(severeexhaustion)
Occasionallyviolentdelirium,stupororcoma.
• 2daysafteronsetsymptomsbecomessevere
• Onthethirddaypatientbegantofeelbetter.
• Howeverthepatientsoondevelopedasorethroatandcoughaswellasirritation/LESIONSonthe
mucusmembraneofthemouth,throat,andrespiratorytract.
• Withindaysskinrushesappears
• Progressingfrommaculartopopular,vesicularandpustular
• Beginstoappearontheface,wristsandankles,spreadstotheextremitiesandofteninareasofpressure
andtightskin.
• Pustulesaslargeas1/3"(8inmindiameter)
• Duringthepustularstagepatient'stemperatureagainroseandearlysymptomsreturned.
- Byday10thepustulesbegantoruptureandeventuallydriedandformedscabs.
- Symptomssubsidedabout14daysafteronset
-Desquamationcommonlyofthescab
took1-2weekscausedintense
pruritusandcommonlypresentpermanentlydisfiguringscars
• Deathresultedfromencephaliticmanifestation,extensivebleedingfrom
:anyorallorificesorsecondary,bacterialinfections.
Diagnosis
1.Cultureofvariolavirus,fromanaspirateofvesiclesandpustules.
2.Microscopicexaminationofsmearsfromlesionscrapingsorvesicle(Guarneribodies)
3.Paul'stestkeratoconjunctivitis
Treatment:
• Hospitalizationwithstrictisolation
• Antimicrobialtherapyforcomplications
• Supportivemeasures
• Symptomatictreatmentoflesionswithantipruritic,startingduringthe pustularstage
• Painreliever
• IV, NGT feeding because pharyngeal lesions made swallowing difficult.
Complications:
• Secondaryskininfections
• Laryngitis,pleurisyandemphysema
• Keratitis.laryngealulcerationswithedema
• Encephalitisandbronchopneumonia
Prevention:Smallpoxvaccination
Chicken Pox Small pox
Characteristic lesion Unilocular- over the body Multilocular- tight areas of the
Non communicate yellow body
scar
Prevention: isolation
MENINGITIS (epidemic Cerebrospinal Meningitis, cerebrospinal fever)
• headache
• photophobia cause is unclear
• malaise
• irritability
• chills and fever
• vomiting seizures–cortical irritability
• increase ICP –widening pulse pressure, irregular RR, headache, vomiting
and decreased LOC
• Childish pitch cry, bulging fontanels
Sign's of meningealirritation
1. nuchalrigidity –stiff neck, an early sign
a. Kernig'ssign pain in the hamstring muscle when attempting to extend the leg
when the hip is flexed.
- Theclientisplacedinsupineposition.Flextheknee,attempttoextendtheleg.Painisexperienced.
b. Brudzinski'ssign –flexionatthehipandkneeinresponsetoforwardflexionoftheneck.
- passiveflexedtheneck,spontaneousflexionofthehipsoccur.
- Diagnosis:
• Lumbar puncture increased ICP elevated WBC, CHON and decreased
glucose. Inc. lymphocytes
-Blood culture
Management:
• Drugs and antibiotics
• Provide nursing care for patient with increase ICP seizures and
hyperthermia -to9 decrease workload of the brain
• Bed rest, keep room quiet and dark
• Monitor fluid and electrolytes imbalance
• Neurologic test
• High protein, calorie, with small frequent feeding.
• Respiratory isolation
Prevention:
Complication
• Pneumonia
• Otitismedia
• Hydrocephalus
ENCEPHALITIS (brain fever)
-acute inflammatory condition of the brain as a complication of various infectious
disease causing manifestations of cerebral dysfunction.
Classification:
a. Primary -virus attacks the brain directly e.g. japanese, stlouis.
MOT: mosquito bites (Culextarsalis, aedessollicitas), infected goat's milk
b. Secondary -occurs as a complication of communicable disease of viral origin
such as measles, mumps, chicken pox
c. Toxic as a result of the of metal poisoning such as lead and mercury.
Clinical Manifestation:
• Lethargy and alteration on the LOC
• Fever, nuchalrigidity
• Headache, convulsions
• Fever chills and vomiting
• Decorticate rigidity: extremities towards cortex
• Decerebraterigidity: hands extension
• Signs of meningealirritation Diagnosis:
• Lumbar puncture -CSF studies
• EEG
• Blood culture -positive for specific microorganism
Management:
• Similar to Meningitis
POLIOMYELITIS (infantile paralysis, (H) Geine-medinDisease)
Etiology :
• Filterable virus
• Legiodebilitans
Type I-Brunhilde
Type II-Lansing
Type III-Leon
Port of entry: Nasopharynx, feces
Incubation Period:
-7-12 days
MOT: direct contact from one person to another
Clinical Manifestation:
• Usually enters in the alimentary tract, multiplies in theoropharynxand
lower intestinal tract.
• Then spreads in the regional lymph node and blood
Manifestation follow three basic forms:
1. Inapparent(subclinical) —95%
2. Abortive( minor illness) (4 —8%) --causes slight fever, malaise, headache, sore
throat, inflamed oropharynx, and vomiting. Recovers usually after 72 hours.
3. Major polio —involves the CNS and takes two form:
a. non —paralytic —produces moderate fever, headache, vomiting, lethargy,
irritability and pain in the neck, back, arms, legs and abdomen.
b. Paralytic —usually develops within 5 —7 days up to onset of fever. Extent of
paralysis depends on the level of the spinal cord lesions.
Types of Paralysis
1. Spinal paralysis -anterior horn cells of the cord are affected; paralysis of
the upper and lower extremities andintercostalmuscle.
2. Bulbar paralysis cranial nerve nuclei affected; respiratory paralysis.
3. Bulbo-spinal paralysis -combination of spinal and bulbar paralysis. a.
Landry’s paralysis -rapid progressive flaccid paralysis starting in the legs,
abdominal and back muscles, arms and neck and the respiratory.
Diagnosis:
• Muscle testing, Lumbar puncture
• Electromyelography—determines the extent of muscle involvement.
• Stool exam
• Pandy'stest —increased CHON in the CSF
Management:
• Maintaincompletebedrestduringacuteperiod.
• Providerespiratoryventilationifrespiratoryparalysisoccurs
• Assistwithphysiotherapy
• Preventpotentialcomplication
Prevention:
• OPV
• Properdisposalofwaste
HEPATITIS
• Widespread inflammation of the liver tissue with liver cell damage due to
hepatic cell degeneration and necrosis
Incubation Period:
-6 months to 9 years
Clinical Manifestation:
PRIMARY INFECTION
• acute mononucleosis like syndrome (fever, fatigue, sore throat
night sweats, GI problems lymphadenopathy. maculopapular
rash and headache)
-anorexia
-Dyspnea
-Fever
-enlarged lymph nodes
- chronically swollen for 3 months
LATENT STAGE
- no signs and symptoms
ETIOLOGIC agent
-Avian influenza virus
Mode of Transmission
- Spreads through air and in humans
- Contaminated feeds, water, equipment, and clothing
- Cats are also thought to be possible infection vectors for H5N1 strains
of Avian virus
- Avian influenza spreads rapidly among birds and no confirmed evidence
of human to human transmission
- There are 15 subtypes known, subtypes. H5 and H7 are known to be
capable of crossing the species barriers
Incubation period
-3-5 days
Signs and symptoms
1. In animals may vary, but for virulent strains can
cause death within few days
2. In humans
- fever, sore throat, cough, and in severe cases
pneumonia
Prevention and Treatment