DAILY INTAKE OF EGGYOLK AND THE EFFECT ON

SERUM CHOLESTEROL OF
RABBIT MODELS
Mary U. Eigbobo and Marshall
A. Azeke
Department of Bochemistry
Ambrose Alli University
Ekpoma

Background Information
Several
ecological
and
epidemiological
studies
have
proved that elevated plasma
levels of total and, in particular,
low-density
lipoprotein
(LDL)
cholesterol are associated with
an increased risk of coronary
and, in general, cardiovascular
events

AIM OF STUDY

Induce Hypercholesterolemia using

graded levels Egg-yolk
administration in rabbit models

Experimentals

Egg yolk
Growers mash
Percentage

Experimental Groups
A
B
C
D
5
10
20
100

95

90

80

5%

10%

20%

Experimentals

Control
Group

Group 2

Group 3

Group 4

No Egg Yolk

5 % EggYolk

10 % EggYolk

20 % EggYolk

Experimentals

Total Cholesterol
HDL-Cholesterol Assay Kits
Total Triglycerides
Friedewald
LDL-Cholesterol

Equation

Results: Feed
Intake/Palatability
Groups

Feed intake

Control

76.53 2.16a

5% egg yolk

77.50 2.36a

10% egg yolk

74.50 1.45a

20% egg yolk

66.68 1.59b

Results: Weight Gain in

kg
Treatment

Body basal

group

Weight

Difference kg

final

(%)

Control

1.10 0.03a

1.31 0.02b 0.21 (19%)

5% egg yolk

1.23 0.03a

1.49 0.02b 0.26 (21%)

10% egg yolk

1.23 0.01a

1.59 0.02b

0.36 (29%)

20% egg yolk

1.26 0.02a

1.62 0.03b

0.36 (28.5%)

Results: Total
Cholesterol

10
3

1
0
4

1
4
3

1
4
9

Results
115
97
66

74

~ Equivalent number of eggs

for a 70 kg adult man
Rabbit

(1.24

kg)
Adult man (70
kg)
~ no of eggs
daily

5g

10 g

20 g

282.25 g

564.0 g

1129 g

14 - 18

28 - 36

56 - 72

Conclusion
5 % Egg Yolk did not result in increase in
Serum Cholesterol
10 and 20 % egg yolk resulted in significant
increase in Total Cholesterol in rabbits
Hypercholesterolemia is not a problem at the
present level of egg consumtion in Nigeria
This could have positive implication for
cholesterol induced hypertension

Thanks for listening

Comments and suggestions
are welcome