Professional Documents
Culture Documents
NEW SCIENCE
NEW SOLUTIONS
NEW APPLICATIONS
CONTENT
1. Introduction to Silfradent Company and development
of Medifuge
2. Medifuge and CGF.
3. How to use Medifuge?
4. Main CGF Medical Application
4.1 Dental Clinic Application
4.2 Other major Medical applications
5. Advantages and Disadvantage
6. Related product (Round Up, & APAG) and accessories
7.Study and clinical paper
8.Technical specification for Round up
1. Introduction of Sifradent
Company
1. Introduction of Silfradent
Company and
development of Medifuge
Today is the world leader in the most advance
techniques
of
Growth
Factors.
Our scientific research and clinical outcomes
demonstrate uniqueness andeffectiveness of our
new CGF system using Concentrated Growth
Factors
&
StemCells.
Silfradent offers a unique, incomparable, easy to
handle and scientifically testedsystem. Reduce
the pain and the intra & post-operative
complication.
ROTOR PHASE
SEPARATOR:
SIFRADENTS ADVANCE
Controlled acceleration
Deceleration control
Cooling
Temperature control
Self-decontamination
ROTOR
SEPARATOR:
SIFRADENTS
ADVANCE
PHASE
ACCESSORIES
MEDIFUGE
It is a preparation of autologous.
Immunologically neutral.
Non-toxic.
VACUTAINER TUBES
"Z No Additives"
with White Cap
no additional
exogenous or
coating here gelled
a coagulum
after separation /
centrifugation
after
approximately 20
min at room
temperature
"Sodium
heparin" with
Green Cap:
Sodium heparin
tube-fed to prevent
the coagulation
remain liquid at
20oC for 8 hours
and at 4oC for 40
h. liquid
MEDIFUGE MF 200
C.G.F.
CONCENTRATED
Red
cap
tube
with
phases
separator
Medifuge, you
obtain a
For
the
preparation
autologous
of
suturable
membrane, particulate to
mix
with
autologous,
heterologous or synthetic
bone.
Biological Guided
Peri-iplantitis
Treatment
www.dentistedu.com
Bone reconstruction
in 45 days
www.dentistedu.com
Pre-op
3 months Post-op
3 years Post-op
IPG DENTISTEDU
DENTISTEDU TECHNIQUE
TECHNIQUE
IPG
I.P.GEORGAKOPOULOS ET
ET ALL,
ALL, JOURNAL
JOURNAL OF
OF IMPLANT
IMPLANT AND
AND ADVANCED
ADVANCED CLINICAL
CLINICAL
I.P.GEORGAKOPOULOS
DENTISTRY, VOLUME
VOLUME 6,
6, NO
NO 1,
1, 20-01-2014
20-01-2014
DENTISTRY,
www.dentistedu.com
New bone formation around the implants I. P. Georgakopoulos et all, JIACD 2014
Conclusions:
IPG-DentistEdu Technique promising results demonstrate that it can be
considered as a reliable alternative to the SFE procedure.
Cone-beam
computed
tomogram showing 1 to 2mm
bone height at the right
maxillary second (left) and first
molar
(right),
respectively
(from patient number 50).
Cone-beam
computed
tomogram
showing 1 to 2mm bone height at the
right maxillary second (left) and first
molar (right), respectively (from
patient number 50).
IMPLANTOLOGY
FASTER HEALING REDUCING COMPLICATIONS
BONE RING
BONE RING
BONE RING
You mix the bone ring after drilling the implant site in the round up (6
sec.) and then fix the the bone ring with the implant.
C.G.F.
CONCENTRATED
White
cap
tube:
phases
with
separator
to
be
used
After
this
separated
naturally jells.
time
the
material
TYPICAL SKIN
DAMAGE DUE TO
EXTENSIVE SUN
EXPOSURE AND
NICOTINE ABUSE
HAND REJUVENATION
3 MONTHS POST-OP
BURN SCARS ON
FOREARM
Improvement after 1
treatment,
3 month post-op.
CGF
best choice for burn scars!
3 months post-op
ONETREATMENT7MONTHSPOSTOP
Onlyinneedledareaserythemaimprovessignificantly
Onlyinneedledareaserythemaimprovessignificantly
Thismightbeahintthaterythemaoflaseredskin
canbereducedbymicroneedling
Intheleftphotoerythemaisobservedalongthekeloidscar
perimeter.Thisistheareaofthescaractivegrowth.However,this
scardiffersfromgrowingkeloid.Theskintoneinthecenterofthe
scarnowhardlydiffersfromnormalskin.Thiskeloidisinactive
andisinthestatusofregression.Suchscarsmaybeexposedto
microneedletherapywithashareofreasonablerisk.
ORTHOPEDIC APPLICATION
The goal of treatment with platelet gel is to stimulate and speed the
healing of connective tissues, which in turn has decreased pain,
increased functional and physiological reparative tissue formation.
Indicated for articular pathologies, tendon and muscle of the knee,
shoulder, wrist, hip, ankle, elbow:
Osteoporosis
Tendinopathy
Epicondylitis
Epitroclea
Gonarthrosis
Coxarthrosis
Rhizoarthrosis
Others
LIQUID
PHASE
TREATING ULCERS
CALCIFICATIONS
POST TRAUMATIC
Dr. Ezio Gheno
PUTRID ULCERS
THE HEALING AT 20 DAYS AFTER SURGERY
PUTRID ULCERS
THE HEALING AT 30 DAYS AFTER SURGERY
Area of peripheral
lesions
ARTICULACION GLENOHUMERAL
ABORDAJE POSTERIOR
ARTICULACION
GLENOHUMERL ABORDAJE ANTERIOR
TENDINOPATHIES
INTERVERTEBRAL DISCS
LIGAMENT SPRAINS
NERVES
MUSCLE STRAINS
FRACTURE NON-UNION
JOINTS
Oral and dental surgery
E.g.
Achilles tendonitis
Lateral/Medial epicondylitis
Rotator Cuff Tendonitis
Patella tendonitis
Chronic Hamstring
Labral tear shoulder
Knee/Shoulder Arthritis
wounds,
vascular
ulcers,
diabetic
surgery,
head
regeneration,
arthroses
fibromyalgia,
scars
of
and
and
the
deep
regeneration, teleangiektasien....
neck
joints,
tendon
pain
wrinkles,
in
skin
ADVANTAGES
ADVANTAGES
Multi-action
treatment.
C.G.F.
provides
healing,
antiinflammatory, antioxidant effects it stimulates collagen, and
proteoglycan synthesis, and plays a significant role in the
defensive function of the skin.
It is a preparation of autologous.
Immunologically neutral.
Non-toxic.
High
Concetrated
Growth
Factors
DISADVANTAGE
CGF-application
99
1ST PHASE
The denaturation of albumin by heating leads to the construction of a web
structure, scaffold.
2ND PHASE
During cooling, the platelets homogenize the above mentioned structures.
MEMBRANE EFFECTS
^ Antipyretic: it gives relief without burning
^ Analgesic: it reduces pain, even in depth
^ Moisturizing: it promotes blood fluid retention in the tissues
^ Fungicidal: it inhibits the growth of fungi
^ Hemostatic: it reduces bleeding
^ Bactericidal: it hinders the growth of bacteria
^ Virustatic: it hibits the growth and development of viruse
^ Detoxifying: it helps the tissue detoxification from previous chemical and
pharmacological treatments
^ Proteolytic and Cicatrizant: it enzymatically dissolves and absorbs dead or
damaged cells, stimulating the regeneration process
APPLICATION
PRP
PRP metodo / CGF: retrogressive
Luer Lock
PROTOCOL EXECUTED
1
21 d
21 d
21 d
21 d
21 d
MINIATURIZATI
ON
Before
2 months after
PRPO3
06 October 2012
07 December. 2012
12 January. 2013
4 months
JUVENTUTE - GREEN
The continuous innovation in science and technologies
in addition to many years of experience in the
marketing of products and services in the world of
aesthetics, is a characteristic of Silfradent Cosmetic.
JUVENTUTE - GREEN
What is new in Juventute cosmetic line:
Exclusive cosmetic line with buffer excipients that
stabilized growth factors and CD34+ cells.
Can enhance the results of existing protocols that use
PRP, PRP gel and CGF.
Can be mixed with vitamins as Vit. D and Vit. B and
Melatonin (protocols by Silfradent)
JUVENTUTE
Helps the immune system with sensitive skin with
Juventute line
INNOVATION
Mask JUVENTUTE (Improve the stabilities of stem cells
Green
and the stability of the growth factors)
pH optimum, maintain physiological
MCH
conditions.
Cream JUVENTUTE - Green pH Buffers, prevents changes in pH
Controlled osmolarity
CRE
Balances the physiological pH of
Lotion JUVENTUTE - Green-the
skin.
- Nutrient / antioxidant
LOZ
CGF
CD34+
Juventut
e
CD34
+
PERSONALIZED COSMETIC
JUVENTUTE (SILFRADENT)
PREPARATION
How to use:
Do facial cleansing with cleansing milk, then apply a thin layer of mask.
After 10-15 min remove very well with warm-cold water then toning with
lotion Juventute - Green LOZ. Before applying any other product, wait at
least 20 min.
Benefits: Juventute - Green MCH mask carries a powerful anti-aging action,
removing free radicals, the accumulation of toxic products of the skin and
activating the endogenous antioxidant cutaneous systems. Juventute - Green
MCH
is a nourishing innovative mask which combines autologous growth factors
with precious natural active ingredients (Green Active Principles ).
15-20 min
LOZ returns the normal physiological pH of the skin.
Strong moisturizing effect.
Benefit:
Lotion Juventute - Green LOZ returns the physiological pH of the skin
to its normal and it has a strong hydrating effect (Green Active
Substances).
RESULTS JUVENTUTE
Aesthetic:
micro-peeling effect, increased tone and
brightness of the skin, enhances the natural color of the
skin.
Anti-Age: removal of toxic substances present in the skin,
both external (pollution, smoke, etc.) and internal.
Functionally: act as a "natural regeneration."
Immunohistochemical staining of CD34 in CGF (A) and RBC (B) layers. The graphs
showed the number of CD34 positive cells in 10 hpf for ten sections in CGF and in RBC
layers (C). *P < 0.05 versus RBC.
Prof. L. F. Rodella
Department of Biomedical Sciences and Biotechnologies,
Division of Human Anatomy, University of Brescia
8.Technical specification
for Round up