Professional Documents
Culture Documents
Regenerative
Medicine
Zach Scheiner,
PhD
Science Officer
Progenitor cell
Stem cell
Stem cell
Skin Cell
Embryonic
pluripotent: can
form
almost any cell type in the human
body
Tissue-Specific (Adult)
multipotent: can form only limited
types of cells (blood, brain, liver,
etc.)
Induced Pluripotent
engineered
Conception
In Vitro Fertilization
in a Dish
In Vitro Fertilization
Day 1
In Vitro Development
Day 1
In Vitro Development
Day 2
In Vitro Development
Day 2
In Vitro Development
Day 3
In Vitro Development
Day 4
In Vitro Development
Day 5
Embryonic
Stem
Cells
Fully mature
Fluorescent imaging of
human embryonic stem cell
colonies
- Heart Disease
- Neurological Diseases
(Parkinsons, Alzheimers,
Huntingtons & others)
- Stroke
- Type 1 Diabetes
- Macular Degeneration (a
and
common cause of blindness)
more!
Cancer
- HIV/AIDS
- Spinal Cord Injury
- Multiple Sclerosis
Trachea transplantation
Example of tissue-specific stem cell-based tissue
replacement
Embryonic Stem-Cell
Derived Heart Muscle
Cells
Applications for
Embryonic Stem
Cells
Video: Diabetes
A CIRM Disease Team
Video:
Age-Related Macular Degene
ration (AMD)
Genetically
engineered
iPS cells
Video: Parkinsonsdisease-ina-dish
Acknowledgements
- Todd Dubnicoff
- Amy Adams
- Laurel Barchas
www.cirm.ca.gov
Extra Slides
Day 7
Day 14
NSCs
injected
(no tumor)
NSCs
injected
(tumor)
Genetically Engineered
Neural Stem Cells
Milestones in Embryonic
Development
Days 7-14: Embryo implants in the uterus
Day 14:
Three distinct layers begin to
form
(no more embryonic stem cells)
Days 14-21: Beginning of future nervous
system
Days 21-24: Beginning of future head,
neck,
mouth, and nose
Weeks 3-8: Beginning of organ formation
Week 8:
Embryo is called a fetus