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Introduction 1
Epilepsy surgery : indicated
for patients with medically
refractory epilepsy.
Children with epilepsy :
10 - 40% medically refractory
epilepsy Surgery
Introduction 2
Medically refractory
epilepsy:
seizures that are not controlled after
an adequate trial with 2 first-line
AEDs.
International League Against
Epilepsy :
a failure of adequate trials of two
tolerated and appropriately chosen
and used AED schedules (whether as
monotherapies or in combination) to
achieve a sustainable free of
seizure
Introduction 3
Advances
in
neuroimaging technologies,
more than 50% of patients
with refractory epilepsy
epilepsy surgery
Objective
To assess the outcome of epilepsy
surgery in children.
Method
RESULT
Table 1. Characteristics of subjects
Characteristics
Age at surgery (years)
Age at onset (years)
Follow up (month)
Mean
12.9
6.4
60.6
Percentage (%)
50
50
59.4
3.1
37.5
6.3
78.1
15.6
81.25
62.5
Chart Title
lesionectomy; 6%
callosotomy; 10%
ATL; 81%
Seizure free :
anti-epileptic
drugs (AED)
discontinuation
Percentage (%)
81.3
56.25
0
postoperative
mortality
Chart Title
4AEDs; 9%
1AED; 28%
3AEDs; 35%
2AEDs; 28%
Outcome
After epilepsy surgeries :
Seizure free : 26 (81,3%) children
Discontinuation of an anti-epileptic
drugs (AED) : 18 (56.25%) children
No postoperative mortality
Discussion
Conclusion
Favourable outcome after epilepsy
surgery can be obtained in children
with medically refracter epilepsy.
Epilepsy surgery is an effective
and safe therapeutic modality in
children with epilepsy
SUGGESTION
Should be measured other outcomes :
developmental and cognitive,
behavioral and psychosocial,
improvement in health-related quality of life
(HRQOL).
THANK YOU