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DISEASE
Departemen Fisiologi
Fakultas Kedokteran
Universitas Sumatera
Utara
Dr. Poland Room 3-007, Sanger Hall, Phone: 8289557
VALVULAR HEART
DISEASE
Dysfunctional cardiac valves
can be classified as:
narrow (stenosis) or,
leaky (regurgitation).
HEART MURMUR
Any disease process that creates
HEART MURMUR
Heart murmurs can be either systolic or
diastolic.
During systole,
systole while the left ventricle
is contracting, the aortic valve is open
and the mitral valve is closed.
Turbulent flow can occur either because
of an incompetent mitral valve,
valve leading
to regurgitation of blood back into the
atrium, or from a narrowed aortic valve.
valve
HEART MURMUR
In diastole,
diastole the situation is reversed,
Tekanan
Peningkatan
Kerja
STENOSIS AORTA
Meningkatnya resistensi terhadap ejeksi
INSUFISIENSI AORTA
Beban volume ventrikel kiri cukup
berat
Ventrikel kiri mengalami dilatasi dan
hipertrofi
PATENT DUCTUS
ARTERIOSUS
Patent ductus arteriosus (PDA) is a
congenital disorder in the heart
where in a neonates ductus
arteriosus fails to close after birth.
ductus arteriosus (DA) is the
vascular connection between the
pulmonary artery and the aortic
arch.
PATENT DUCTUS
ARTERIOSUS
In normal newborns, the DA is
substantially closed within 1224 hours
after birth, and is completely sealed after
three weeks.
When the newborn takes its first breath,
the lungs open and pulmonary vascular
resistance decreases.
After birth, the lungs release bradykinin to
constrict the smooth muscle wall of the
DA and reduce bloodflow through the DA
as it narrows and completely closes,
usually within the first few weeks of life
PATENT DUCTUS
ARTERIOSUS
patent ductus arteriosus is associated
with a continuous murmur because of
a persistent connection between the
pulmonary artery and the aorta.
A patent ductus arteriosus allows a
portion of the oxygenated blood from
the left heart to flow back to the lungs
by flowing from the aorta (which has
higher pressure) to the pulmonary
artery.
Tetralogy
Pulmonary stenosis
Overriding aorta; an aortic valve
with biventricular connection.
3. Ventricular septal defect (vsd);
hole between the two bottom
chambers (ventricles) of the heart
4. Right ventricular hypertrophy
1.
2.
Let it
beat!