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General Characteristics
Rod-shaped
Gram-Negative
One or more polar flagella
Strictly aerobic
Straight or curve
Non-Spore Forming
Pseudomonas fluorescens
Pseudomonas aeruginosa
Classification
Pseudomonas:
A genus of Gram-negative
aerobic
gammaproteobacteria
Family
ofPseudomonadaceae
Classification history
was first classified at the end of
Ecology
can be found in soil, marshes,
Ecology
(cont.)
Pseudomonas aeruginosa
Actively motile
Nonspore- forming
Oxidase- positive bacillus
"epitome" of opportunistic
pathogens
Clinical relevance
second-most-common infection in
hospitalized patients
mildly pathogenic; almost never
infects uncompromised tissues but
infect practically any type of tissue if
that tissue has some type of
compromised defenses
most common pathogen isolated
from patients who have been
in patients with:
Nosocomial Infections
o Sinus
infections;
bronchopneumonia
o Urinary Tract Infection (UTI)
Burns and wound infections
Cystic Fibrosis
bronchopneumonia
Source: equipments that are
hard to clean and sterilize
such as face mask, certain
kinds of humid rubber tubing
nebulizer, and parts of
intermittent positive- pressure
Prevention:
Victim
infections
P. aeruginosa from soil and
feces is notorious for
causing deep, antibioticresistant infections.
Secretes enzymes which
Pseudomonas
pseudomallei
Gram- negative
Motile
Nonpigmented bacillus
Clinical relevance
Pseudomonas pseudomallei
causes meliodosis an uncommon
tropical disease
Its pulmonary manifestations are easily
confused with those of tuberculosis
May be septicemia with wide lesions
over the body
Nicknamed Vietnamese time bomb
Antibiotic resistance of
Pseudomonas
mostPseudomonas spp.are
naturally resistant to
penicillinand the majority of
relatedbeta-lactam antibiotics
number are sensitive
topiperacillin,imipenem,ticar
cillin, orciprofloxacin
Antibiotic resistance of
Pseudomonas
This ability to thrive in harsh
Aeromo
nas
Characteristics
Gram-negative
facultative anaerobic rod
morphologically resembles
members of the
familyEnterobacteriaceae
beta-hemolytic on blood agar
oxidase positive
Aeromonas hydophila
Etymology
Greeknounaer, aeros which
Clinical relevance
Two major diseases associated
withAeromonasaregastroenteritisan
d wound infections, with or
withoutbacteremia
Although some potential virulence
factors
(e.g.endotoxins,hemolysins,enterot
oxins, adherence factors) have been
identified, their precise role is unknown.
disease
inimmunocompromisedpatients
diarrheal disease in otherwise
healthy individuals, and
wound infections
resemblesshigellosis
with blood and leukocytes in the
stool
Acute diarrheal disease is self
limited
and only supportive care is
indicated in affected patients