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RESTU FADILAH H.F.
PRISYLIA SHINTANINGRUM
LAILATUL MAGHFIROH
RIKA ERFIANA D.
MELATI NISA A.
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History of cloning
1962 - John Gurdon claims to have cloned frogs from adult cells.
1963 - J.B.S. Haldane coins the term 'clone.'
1966 - Establishment of the complete genetic code.
1967 - Enzyme DNA ligase isolated.
1969 - Shapiero and Beckwith isolate the first gene.
1970 - First restriction enzyme isolated.
1972 - Paul Berg creates the first recombinant DNA molecules.
1973 - Cohen and Boyer create first recombinant DNA organisms.
1977 - Karl Illmensee claims to have created mice with only one parent.
1979 - Karl Illmensee makes claim to have cloned three mice.
1983 - Kary B. Mullis develops the polymerase chain reaction technique
for rapid DNA synthesis.
1983 - Solter and McGrath fuse a mouse embryo cell with an egg without a
nucleus, but fail to clone using their technique.
1984 - Steen Willadsen clones sheep from embryo cells
1985 - Steen Willadsen clones sheep from embryo cells. Steen Willadsen joins
Grenad Genetics to commercially clone cattle.
1986 - Steen Willadsen clones cattle from differentiated cells.
1986 - First, Prather, and Eyestone clone a cow from embryo cells.
1990 - Human Genome Project begins
1996 - Dolly, the first animal cloned from adult cells, born.
Steps in Cloning
Step 1: Take any cell from your body, from the skin, for example.
Step 2: Take an egg cell (ovum), from the ovary of any woman.
Step 3: Take the nucleus out of the egg cell.
Step 4: Put together the cell of your skin and the egg
without nucleus. It will start to multiply forming a microspic
ball of many identical cells.
Step 5: In about 6 days place it in the uterus of the woman.
Step 6: In 9 months a baby will be born just like you,
an identical twin of you without any genetic
characteristics of the woman who gave the ovule and
provided the uterus, and gave birth to your twin.
Transgenic clones