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STORAGE
Abdul Salam M. Sofro
Faculty of Medicine
YARSI University
Learning objectives
Triacylglycerol (TAG)
Phospholipids
Cholesterol
Cholesteryl ester
Another plasma lipid: Free Fatty Acids (FFA)
only 5% of the total FA present in the plasma
and the most metabolically active plasma lipid
Phospholipid Structures
Phosphatidylcholine (PC)
Phosphatidylethanolamine (PE)
Phosphatidylserine (PS)
Cont.
Function of lipoproteins
Chylomicrons
Transport triacylglycerols from intestines to other tissue
except kidneys
VLDL
Bind triacylglycerols in liver and carry them to fat tissue
LDL
Carry cholesterol to peripheral tissues
HDL
Bound to plasma cholesterol. Transport cholesterol to
liver
Source
Protein
(%)
Total lipid
(%)
TAG
(%)
Chylomicrons
Chylomicron
remnants
VLDL
IDL
LDL
Intestine
Chylomicrons
1-2
6-8
98-99
92-94
88
80
Liver (intestine)
VLDL
VLDL
7-10
11
21
90-93
89
79
56
29
13
HDL1
HDL2
HDL3
Pre--HDL
32
33
57
70
68
67
43
30
2
16
13
-
Albumin-FFA
Adipose tissue
99
Lipoproteins
Molecular
Mass (Da)
Apo A-I
HDL, Chylomicrons
28,000
Apo A-II
HDL, Chylomicrons
17,000
Apo A-IV
46,000
Apo B-100
550,000
Apo B-48
260,000
Apo C-I
7,6000
Apo C-II
8,916
Apo C-III
8,750
Apo D
Subfraction of HDL
19,300
Apo E
34,000
Note: