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SYSTEM
CEREBROVASCULAR SYSTEM
• Brain makes up only of about 2% of total body
weight in adults
• It receives 15% - 17% of the total cardiac
output
• It consumes about 20% of the oxygen used by
the entire body (3.5 ml/100 gm/min)
• Cerebral blood flow at rest is 50-55 ml/100 gm
/min)
CEREBROVASCULAR SYSTEM
• PaO2 < 45 mm Hg – difficulty with complex
task learning & short term memory
• PaO2 = 30 mm Hg – cognitive disturbance &
incoordination
• PaO2 < 20 mm Hg – comatous
• Loss of consciousness if brain deprived of
blood for 10=12 seconds; after 3-5 min.
irreparable damage or death may result
CIRCLE OF WILLIS PERFORATING BRANCHES
INTERNAL CAROTID ARTERY
A4 segment
A3 segment
A2 segment
Vein of Galen
Straight Sinus
Confluence of sinus
Transverse sinus
Sigmoid sinus