1.

Resting membrane potential of

cardiac muscle is ?
- 90 mV
2. Deficiency of which transporter is
associated with low CSF glucose,
neonatal seizures and MR ?
GLUT - 1
3. Climbing fibers carry impulses to
the cerebellum from ?
Inferior olivary nucleus.
4. Desoxiben mechanism of
action ?
Selective Tx A
2
synthetase
inhibitor.

5. Name a p-FOX inhibitor.
Ranolazine and Trimetazidine.
6. Which beta lactam antibiotic can
be safely used in patient allergic to
penicillin?
Monobactam Aztreonam.
7. Three amino acids used for the
synthesis of glutathione are ?
Glutamate, glycine and cysteine.
8. Organelle involved in
ubiquitin tagged protein
degradation is ?
Proteasome.
9. Skin lesion shows coral red
fluorescence under Woods lamp.
What is the organism causing the
lesion ?
Corynebacterium minutissinum.
10. Pigment responsible for
pseudohemoptysis ?
Prodigiosin.
11. Only gram positive bacteria
causing interstitial pneumonia ?
Streptococcus agalactiae.
12. Priapism is associated with
which poisoning ?
Cantharides.
13. Spider cells are classical of
which tumor ?
Rhabdomyoma?
14. Which growth factor is also
called scatter factor ?
Hepatocyte growth factor.
15. Fractured tubular casts are
seen in ?
Myeloma kidney.
16. Components of Guy ropes.
Sartorius, gracilis and
semitendinosus.
17. Maxillary artery is divided into
three parts by what structure ?
Deep head of Lateral pterygoid.
18. Which is the most common site
for ectopic pancreatic tissue?
Stomach.
1. A 42 year old man with CRF has
the following chest CT picture.
Diagnosis ?
2. 18 yr old male presents with
fever, sore throat, loss of appetite,
lymphadenopathy, maculopapular
rash and hepatosplenomagaly.
Blood smear revealed atypical T
cells. Patient suddenly develops
abdominal pain, tachycardia and
BP 70/20. Patient collapses and
dies. What is the cause of death ?
3. A 52 yr old male comes to casualty
with fever, malaise and chest pain.
He was diagnosed to have a viral
syndrome and sent home. Next day
he is brought in comatose state with
septic shock.CXR shows mediastinal
widening with B/L pleural effusions. 5
days ago he had attended a national
conference. 20 people of the same
conference developed similar illness
and 12 died. What is the likely cause?
4. A 10 months infant presents
with failure to thrive, seizures
and is not alert. ABG shows low
pH. Ammonia level in blood is
increased. Hair is tufted, coarse
and brittle. What is the enzyme
deficiency that has caused this
condition ?
5. A 6 month old female baby presents with severe
intractable multiple episodes of seizures with EEG
showing independent activity in both hemispheres.
CT and fundoscopy showed these features.
Diagnosis ?
6. 70 year old chronic smoker with
history of lung mass treated with
radiation presents with seizures.
His former and present lab results
show Na-110, K-3.5,Ca-10.5 and
glucose-96. He was treated with
3% saline. Next day morning, the
patient became disoriented and
quadriplegic. What is the diagnosis
? What is the IOC to confirm the
disease ?

7. A 19 yr old girl who is suffering from

bulimia nervosa develops sudden severe
chest pain after a binge of vomiting. X ray
shows the following. Diagnosis ?
8. A patient with history of CVA
presents to the casualty with
complete unresponsiveness to
any modality of stimulus. There
is no visible motor activity. The
only movements that are
possible are vertical eye
movements and winking.
Diagnosis ?
9. A 4 yr old boy presents with
abdominal pain. He was toxic and
tachypneic to look at, there were no
palpable organs, no rigidity or
abdominal tenderness. The intern
ordered for an abdominal series
and he set them aside as being
normal, although it depicted a
subtle sign of a very common
disorder.
Diagnosis ?
10. A 40 year old man who was on hip spica for 3
months developed vomiting and abdominal
distension. On examination, VGPs were seen.
Barium swallow showed -
CT showed -
1.Drug of choice for medical adrenalectomy ?
2. Stored blood is deficient in which clotting factors ?
3. Fruit juice preventing UTI ?
4. 2
nd
MC organism in cystic fibrosis ?
5. IOC to screen IVH in newborn ?
6. MC site for ischemic colitis ?
7. MC organ involved in penetrating injury abdomen ?
8. MCC of death in Ca penis ?
9. Most pronounced symptom in small bowel
obstruction ?
10. MC cardiac lesion in child born to PKU mother ?

1.Drug of choice for medical
adrenalectomy ?

2. Stored blood is deficient in
which clotting factors ?

Factors v and vii
3. Fruit juice preventing UTI ?

Cranberry juice.
4. 2
nd
MC organism in cystic
fibrosis ?

Staph aureus.

5. IOC to screen IVH in
newborn ?

Neuro sonogram.

6. MC site for ischemic colitis ?

Splenic flexure.
7. MC organ involved in
penetrating injury abdomen ?

Small intestine.
8. MCC of death in Ca penis
?

Femoral artery erosion and bleed.

9. Most pronounced symptom
in small bowel obstruction ?

Pain.
10. MC cardiac lesion in child
born to PKU mother ?
Mitral regurgitation.

1. MCC of death in Menkes kinky hair disease ?
2. Disease with 100% HLA association ?
3. % of HbS in sickle cell trait ?
4. MCC of death in cong diaphragmatic hernia?
5. Blue diaper disease ?
6. Cetrimide test used in diagnosis of ?
7. TOC for anal Ca ?
8. MC hernia in females ?
9. MC site for metastasis for lung Ca ?
10. Tylosis is association with which Ca ?

1. MCC of death in Menkes
kinky hair disease ?

Aoric dissection.
2. Disease with 100% HLA
association ?

Narcolepsy.

3. % of HbS in sickle cell trait ?

40 %
4. MCC of death in cong
diaphragmatic hernia?

Pulmonary hypoplasia.

5. Blue diaper disease ?

Hartnups disease.
6. Cetrimide test used in
diagnosis of ?

Mucopolysacchradosis.

7. TOC for anal Ca ?

Chemoradiation by Nigros
protocol.
8. MC hernia in females ?

Inguinal hernia.

9. MC site for metastasis for
lung Ca ?

Adrenal gland.
10. Tylosis is association with
which Ca ?
Esophageal cancer.

1. MC congenital immunodeficiency?
2. Most specific anomaly in IDM ?
3. Expand NESTROF.
4. Treatment for multiple carboxylase deficiency ?
5. MC muscle biopsied in neuromuscular disorders ?
6. Vit C is seen in highest concentrations in which
organ ?
7. MC complication in ERCP?
8. Only indication for operation in acute pancreatitis ?
9. MC site for subphrenic abscess ?
10. Antibacterial present in prostatic secretion ?

1. MC congenital
immunodeficiency?

Ig A deficiency.
2. Most specific anomaly in
IDM ?

Caudal regression or sacral agenesis.

3. Expand NESTROF.

Naked Eye Single Tube Red cell
Osmotic Fragility test.
4. Treatment for multiple
carboxylase deficiency ?

Biotin.
5. MC muscle biopsied in
neuromuscular disorders ?

Vastus lateralis.
6. Vit C is seen in highest
concentrations in which
organ ?

Adrenal gland.
7. MC complication in ERCP?

Acute pancreatitis.
8. Only indication for
operation in acute
pancreatitis ?

Necrosis: necrosectomy.
9. MC site for subphrenic
abscess ?

Morrisons pouch: right posterior
space.
10. Antibacterial present in
prostatic secretion ?
Zinc.

1. Complication that does not revert after treatment
in hemochromatosis.
2. MC complication of H influenza meningitis.
3. Element regulates Na-K channel.
4. MC cause of CCF in first week?
5. Most potent vasodilating substance in body?
6. MC presentation in Wiskott Aldrich syndrome?
7. Hunterian ligature is used in?
8. Abbey Eslander flap is used in reconstruction of?
9. Components of Saints triad?
10. MC variety of mesenteric cyst?

1. Complication that does
not revert after treatment in
hemochromatosis.

Arthropathy and gonadal atrophy.
2. MC complication of H
influenza meningitis.

Subdural effusion.
3. Element regulates Na-K
channel.

Vanadium.
4. MC cause of CCF in first
week?

Transposition of great vessels.
5. Most potent vasodilating
substance in body?

Calcitonin gene related peptide.
6. MC presentation in Wiskott
Aldrich syndrome?

Thrombocytopenia: bleeding.
7. Hunterian ligature is used
in?

Arterial aneurysms.
8. Abbey Eslander flap is
used in reconstruction of?

Lip reconstruction.
9. Components of Saints
triad?

Gall stones, colonic diverticulosis
and hiatus hernia.
10. MC variety of mesenteric
cyst?
Chylolymphatic.
1.
1. Stem cell therapy was first employed in which disease ?
2. Only amino aciduria which does not cause mental
retardation.
3. Shrinking lung syndrome is seen in which disease?
4. Supermammary nipples is the teratogenic effect of which
drug?
5. Defect most common in congenital rubella syndrome?
6. MC organism responsible for floppy infant syndrome ?
7. Stafne bone cyst ?
8. TOC for annular pancreas ?
9. Salmonella species that affects the colon ?
10. Renal cystic disease where kidney is shrunken?

1. Stem cell therapy was first
employed in which disease ?

Severe combined immuno
deficiency.
2. Only amino aciduria which
does not cause mental
retardation.

Alkaptonuria.
3. Shrinking lung syndrome is
seen in which disease?

SLE.
4. Supermammary nipples is
the teratogenic effect of which
drug?

Ethambutol.
5. Defect most common in
congenital rubella
syndrome?

Deafness.
6. MC organism responsible
for floppy infant syndrome ?

Clostridium botulinum.
7. Stafne bone cyst ?

Ectopic salivary gland tissue in
mandible.
8. TOC for annular pancreas ?

Duodeno-duodenostomy or duodeno-
jejunostomy.
9. Salmonella species that
affects the colon ?

Paratyphi B.
10. Renal cystic disease where
kidney is shrunken?
Medullary Cystic Kidney disease.

1. MC cause of acute pancreatitis in children?
2. Neonatal seizure with best prognosis ?
3. Mineral used in treatment of persistent
diarrhoea.
4. MC cause of daytime somnolence?
5. Treatment for breath holding spells.
6. Non metastatic liver enzyme elevation in RCC
Syndrome?
7. Staghorn calculi is seen in which infection?
8. Rovsings operation is done in ?
9. MC site of SRUS ?
10. MC intrauterine infection ?

1. MC cause of acute
pancreatitis in children?

Trauma.
2. Neonatal seizure with best
prognosis ?

Hypocalcemic seizures.
3. Mineral used in treatment of
persistent diarrhoea.

Zinc.
4. MC cause of daytime
somnolence?

Sleep apnea.
5. Treatment for breath holding
spells.

Iron therapy.
6. Non metastatic liver enzyme
elevation in RCC
Syndrome?

Strauffers syndrome.
7. Staghorn calculi is seen in
which infection?

Proteus infection.

8. Rovsings operation is
done in ?

ADPKD.
9. MC site of SRUS ?

Anterior rectal wall.
10. MC intrauterine infection ?
CMV.
1. What sign is this and in which
disease is this seen ?
Panda sign in
sarcoidosis.
2. What do you see here ?
Absent patella:
Nail Patella
syndrome.
3. This is a post contrast film.
Diagnosis ?
Aortic dissection.
4. What is this skin manifestation of
a zoonosis ?
Erythema
chronicum migrans
in lymes disease.
5. Diagnosis ?
Kippel Feil syndrome.
6. What is the finding in the iris ?
Brushfield spots.
7. Parietal swellings with pain.
Diagnosis ?
dercums disease.
8. What heavy metal poisoning
is this a feature of ?
Silver.
9. Histology of cardiac muscle.
What is the infection ?
T cruzi: Chagas
disease.
10. What is this skin lesion ?
Erythema marginatum.
11. Highest esophageal pressure is
seen in this spastic condition.
Diagnosis ?
Nut-cracker
esophagus.
12. Diagnosis ?
Aspergilloma
Meniscus sign.
13. Diagnosis ?
TAPVC.
14. This endocarditis commonly
leads to what functional valvular
abnormality ?
Mitral regurgitation.
15. What is this appearance
called ?
Chain of lakes
appearance.
16. Diagnosis ?
Pancreas divisum.
17. Diagnosis ?
Acute pancreatitis.
18. Organism causing this grave
disease ?
Clostridium welchii.
19. Diagnosis ?
Fluorosis.
20. What is this finding ?
Splinter hemorrhages.
21. Diagnosis ?
Renal osteodystrophy.
22. Diagnosis ?
Schistosomiasis.
23. Organism causing this
disease ?
H influenza.
24. This deformity was mechanically
correctable. It resolved without any
sequelae. What is this called ?
jaccouds arthropathy.
25. What is this skin lesion ?
Erythema nodosum.
26. What is the DOC for
arthropathy in this condition ?
Methotrexate.
1a. What is this ?
Female condom.
b. Which uterine infection is an
early complication of Cu T
insertion?
Actinomycosis.
c. A 28 yr old lady on OCPs for
5 yrs comes with DVT. What is
the genetic defect in coagulation
you suspect in this pt. ?
Factor v leiden mutation
2a. Identify this instrument.
Pediatric laryngoscope magill /
miller blade.
b. Best anesthetic circuit for
spontaneously breathing
adults is ?
Mapleson type A.
c. Drug of choice for total
intravenous anesthesia ?
Propofol + remifentanyl.
3a. Identify this instrument.
Praders orchidometer.
b. Penis at 12 syndrome is due
to congenital deficiency of which
enzyme ?
5 alpha reductase.
c. A newborn had hypoglycemic
seizures and microphallus with
normal testis and scrotum. What
do you suspect?
hypopituitarism.
4a. Identify this picture.
Haversian system in bone.
b. Ivory vertebra is seen in ?
Pagets disease.
c. Retrolisthesis is most
common between which two
vertebra ?
Between L4 and L5.
5a. This histological picture is
diagnostic of ?
Rheumatic carditis.
b. Mc Callum plaques are most
common in which chamber ?
Left atrium.
c. Cross reaction of antibody
against which bacterial antigen with
the heart causes rheumatic
valvulitis ?
Group specific carbohydrate.
Surrogate marker for pancreatic
rejection in SPKT is ?
Serum creatinine.
Mycophenolate mofetil
mechanism of action ?
IMP dehydrogenase inhibition.
Optimum storage time for
kidney after procurement is ?
24 hrs.
Commonly used storage
medium for corneal
transplantation is ?
MK medium.
Infection causing hematopoietic
stem cell transplant failure is ?
CMV.
Simultaneous liver and kidney
transplantation is required in which
disorder ?
Hyper oxaluria.
Which MAB produces PML as
side effect ?
Natalizumab
MAB against RANK ligand
used in osteporosis
Denozumab
MAB against CD 33 used in
AML is ?
Gemtuzumab ozagamycin.
Tositumomab is directed
against ?
CD - 20
Pavalizumab is directed against
which virus ?
RSV
MAB used in psoriasis is
directed against ?
CD 11a
Cardiovascular complication of
facio-scapular humeral dystrophy.
Labile hypertension
Sarcoglycan abnormalities are
seen in which myopathy ?
Limb girdle muscular dystrophy.
Myopathy associated with
malignant hyperthermia ?
Central core disease.
First muscle to undergo
contracture in Duchennes
muscular dystrophy ?
Achilles tendon
Toxicity of which drug causes
red ragged fibres in skeletal
muscles ?
Zidovudine.
Triad of progressive external
ophthalmoplegia, retinitis
pigmentosa and cerebellar
ataxia is called ?
Kearns sayre syndrome
GBS is the PNS of which
disease ?
Hodgkins lymphoma
Secretion of which product most
commonly causes hyper
calcemia ?
PTH rP
Antibodies against glutamic acid
decarboxylase is seen in which
paraneoplastic disorder ?
Stiff person syndrome.
Increased secretion of what
substance causes
thrombocytosis ?
IL - 6
Oncogenic osteomalacia is due
to secretion of ?
FGF - 23
Skin lesion seen in
glucagonoma ?
Migratory necrolytic erythema.
Most common lymphoma
asociated with RA ?
DLBCL
Characteristic echo feature of
amyloidosis is ?
Granular sparkling sign.
Antibody associated with
neuropsychiatric manifestations
in SLE is ?
Anti ribosomal P antibody.
A patient on chronic dialysis
develops carpal tunnel syndrome.
Which protein, forming amyloid, is
responsible ?
A beta 2 microglobulin.
Polymyalgia rheumatica is
associated with which vasculitis ?
Giant cell temporal arteritis.
Antibody specific for Mixed
connective tissue disorder is ?
Anti U1 RNP.
Ostmann pad of fat is
present in
Eustachian tube.
Purtschers retinopathy is an
acute complication of
Acute pancreatitis.
Surgical approach used for
cochlear implantation is ?
Facial recess approach.
Posterior embryotoxon ?
Prominent Scwalbes line
What immunological abnormality
will you expect in the 15 day old
baby shown in the picture below.

Leucocyte Adhesion Deficiency
Type 1
A malnourished child presents with lethargy
malaise & failure to thrive.lab results:Hb markedly
decreased,thrombocyte & lymphocyte levels
normal,iron B12 folate normal,bone marrow biopsy
revealed








the most appropriate treatment for this child is
I. V. Immunoglobulins
60 yr old man presents with hepato
splenomegaly, palatal edema &
lymphadenopathy. Diagnosis ?
Franklins diease
20 yr old man presents with symptom suggestive
of bone marrow failure. hematological picture was








He was treated. 20 days later, he developed
dyspnoea chest pain. X-ray revealed cardiac &
pulmonary effusion. Give the diagnosis, most
probable treatment given & explanation for the
current symptoms.
Diagnosis AML M3.
Treatment is retinoic acid.
The current scenario is retinoic acid
syndrome devoloping due to sequestration
of leukemic cells in pulmonary
vasculature.
23 yr old primi with 6 weeks
amennorhoea diagnosed to have
ovarian cyst. Best time to operate
in pregnancy is ?

12-18 Weeks
Ovarian tumour which is 100%
unilateral

Yolk sac tumour.
Diagnosis ?
Tubal ectopic.
24 yr old women with 28 weeks of
amennorhoea diagnosed to have
ca cervix of stage IA-1.Treatment
of choice is ?

Caesarian hysterectomy
Gastric carcinoma in pernicious
anemia involves which part of
the stomach?
Fundus.
This childhood tumour has a great
tendency to regress spontaneously
Neuroblastoma.
25 yr woman presents with vague
headache especially in early morning
with vomiting and blurring of vision.
Diagnosis ?
Meningioma of the tentorium,
with dural tail sign.
Biopsy of a malignant liver tumor in a 35 yr
old woman showed








Name a tumor marker specific for this case?
Neurotensin.
Vitamin B12 binding globulin.
Only bone of foot without any
muscle attachments.
Talus.
50. Diagnosis ?
Intraosseous hemangioma spine,
corduroy appearance.
The angle at which the elbow has
to be immobilized in treating this
condition is
30 degrees.
Name the crystal arthropathy in
which crystals cannot be visualized
by polarized light microscopy ?
Calcium hydroxyapetite.
Apparatus designed to find out
the dose of bleaching powder
required for the disinfection of
water.
Horrocks apparatus.
In typhoid, carriers who are most
dangerous (by means of portal of
exit of infection) are ?
Urinary carriers.
3 yr old boy had high grade fever
with mild pharyngitis for 4 days.
Then temperature dropped down
rapidly and then he developed
maculopapular rash in trunk
extending to face and extremities.
Post auricular lymph nodes were
enlarged on examination.
Diagnosis ?
Roseola infantum.