Gold Pharm CNS

Short -acting BDZs:

 TOM Triazolam Onazelam Midazolam

 B t!ro"henone

 #alo"eridol $ Dro"eridol

 %t!"ical D&

 Cloza"ine - Thioridazine Olanze"ine - 'is"eridone ( Do not ca se )PS

 *l mazenil

BDZ antidote +or OD

 Phen!toin

 Ca ses a"lastic anemia, gingi-al h!"er"lasia, cle+t li" $ "alate

 Thio"ental

 Short acting Bar.

 Car.amaze"ine

DOC trigeminal ne ralgia/ T0t lenno0 gesta t seiz res in 1ids

 %t!"ical D&-r

 Thioridazine2 Olamza"ine2 Cloza"ine

 Pimozide

T0t To rette3s

 'is"eridone

 Good +or negati-e s!m"toms

 Thioridazine

 Most anti cholinergic ne role"tic

 #alo"eridol

 Ne role"tic malignant h!"erthermia d e to chronic D4 .loc1/ gi-e Dantrolene and Bromocri"tine

 5mir"amine

)n risis

 Clomir"ramine

 T0t OCD See aggressi-e .eha-ior 6, se

 Trazadone

 Pria"ism

 B "ro"ion

#el"s to 7 it smo1ing

 SS'5s

Primaril! sed +or OCD

 *l o0etine

Good +or negati-e s!m"toms

 Phenelzine

5rre-ersi.le M%O5

 8ithi m

 T0t manic "hase o+ Bi"olar Disorder Ca ses goiter .! 9-: con-ersion o+ T& to T; Ne"hrogenic dia.etes insi"id s 8o6 salt diet 6ill lead to 8i to0icit!

 %l"razolam

DOC stage +right

 Pro"ranolol

Social "ho.ia

 -r

 S"inal analgesia/ ) "horia/ <<e "horia/ < <sedation/ Consti"ation/

 -r

 S "ras"inal analgesia/ D!s"horia/ <res"irator! de"ression/ <sedation/

 Mor"hine $ O4

 %dmin/ is contraindicated to "ts on mor"hine sedation( decrease CO4 sensiti-it! and O4 admin/ can sto" .reathing/

 Mor"hine

 5ncrease 5CP ( do not gi-e to "t/ 6ith head tra ma

 Mor"hine OD

 =/"in"oint " "ils 4/ decrease res"iraiton ;/coma

 Me"eridine

%nesthetic sed d ring la.or

 #!dromor"hone

 9<: sed in renal +ail re

 Tramadol

 %m. lator! t0t +or mod/ to se-ere "ain

 Part 9<: $ "art 9-:

 Pentazocine B tor"henol Nal. "hene

 decrease G%B%

decrease seiz re +oc s( Bar.s $ BDZs

 decrease *ast Na Ch/

decrease electrical acti-it! s"read ( Phen!toin $ Car.amaze"ine

 Metho0!+l rane

 Can .e ne"hroto0ic/ Needs lo6 M%C +or anesthetic ind ction/

 )n+l rane

 Can ca se tonic,clonic m scle s"asms

 5so+l rane

Can ca se .ronchos"asm

 #alothane

 Can ca se -entric lar e0tras!stoles $ Malignant h!"erthermia $ #e"atitis

 Nitric O0ide

No e++ect on #'/ Needs high M%C +or anesthetic ind ction/

 Thio"ental

Short acting Bar./

 Dro"eridol

 Can .e sed in com.o 6, *entan!l +or ne role"toanalgesic e++ect Ne role"tic tran7 ilizer/ #as mild al"ha .loc1

 *entan!l

 Can .e sed on com.o 6, Dro"eridol +or ne role"toanalgesic e++ect >sed transdermall! +or chronic "ain

 Midazolam

 Pre anesthetic/ 5nd ces amnesia

 Primidone

Biotrans+ormed to Pheno.ar./

 *irst +i.ers to .e .loc1ed 6, anesthesia

 C $ % delta *i.ers

 )sters

 Procaine? Tetracaine? Benzocaine Bro1en do6n and ma1e P%B% 9allergen:

 %mides

 8idocaine? Me"i-aciane? B "i-aciane? )tidocaine( i .e+ore caine al6a!s an amide Meta.olized in the li-er

 %m"hetamine

D% re "ta1e 9-:3r/ M%O5/ Par1inson3s t0t

 Bromocri"tine

D49<:/ >sed 6, 8Do"a +or on-o++ "henomenon o+ Par1inson3s

 Benztro"ine

%nt M 6, some D% re "ta1e 9-:/ Par1inson3s t0t

 %mantidine

decrease D% re "ta1e/ Can ca se li-ido retic laris( s1in mottling/

 Di"henh!dramine

T0t earl! Par1inson3s stages

 Pergolide

@ )++ecti-e $ longer acting than Bromocri"tine

 Tran!lc!"romine

M%O5 ( antide"ressant

 SS'5 $ M%O5

 *atal com.o? es"eciall! seen 6ith the se o+ Paro0etine or *l o0etine 9SS'5s: and Tran!lc!"romine 9M%O5:

 8a.or o"ioids

 Me"eridine $ Nal. "hine

 Desi"ramine ca ses

 S dden cardaic death in children