A Short Introduction to Future Approaches in Chronic Diseases Dr.

Serdar Sava United Health Systems

Epidemiologic and Demographic Transition

Epidemiologic and Demographic Transition

Fertility Mortality

First Stage

Epidemiologic and Demographic Transition

Fertility Mortality

First Stage

Second Stage

Epidemiologic and Demographic Transition

Fertility Mortality

First Stage

Second Stage

Third Stage

Epidemiologic and Demographic Transition

Fertility Mortality

First Stage

Second Stage

Third Stage

Fourth Stage

Epidemiologic and Demographic Transition

Fertility Mortality

First Stage

Second Stage

Third Stage

Fourth Stage

Near Future

Results of 5th Stage of Demographic and Epidemiologic Transition

Aging Society Increase in chronic complex diseases: Heart attacks Strokes Cancers Type 2 Diabetes Obesity Osteoporosis Other Degenerative Diseases

95% of TOTAL DISEASE BURDEN

Threshold of Disease ________________________________________

Threshold of Disease ________________________________________

Genetic

Genetic diseases

Threshold of Disease ________________________________________

Exogenous Factors Genetic

Genetic diseases

Exogenous Diseases

Threshold of Disease ________________________________________

Life Style Exogenous Factors Genetic

Genetic diseases

Exogenous Diseases

Complex Diseases

Threshold of Disease

Threshold of First Symptom

Check-up Diagnosis and Early and Diagnosis Treatment Life Style and Exogenous Factors
Conception

Genetic Susceptibility
Pathology Development Phase I
First Disease Symtoms Phase III Phase II

Death

Human Genome Project

Institute of Medicine, USA, 2005

Dr. S. Sava

Dr. S. Sava

4P Medicine
Participatory Predictive Preventive Personalized

Follow up Management Training

Risk Disease Case

Risk of Type 2 Diabetes in Next 30 Years

Age

Dr. S. Sava

Risk of Type 2 Diabetes in Next 30 Years when Optimum Life Plan is Applied

Age

Dr. S. Sava

Risk of Heart Attack in Next 30 Years

RISK %

Age

Dr. S. Sava

Risk of Heart Attack in Next 30 Years when Optimum Life Plan is Applied

RISK %

Age

Dr. S. Sava

Risk of Stroke in Next 30 Years

RISK %

Age

Dr. S. Sava

Risk of Stroke in Next 30 Years when Optimum Life Plan is Applied

Dr. S. Sava

Lung Cancer Risk

Reference

High
Your Current Risk

Medium
Optimum Life and Medical Follow-up Plan Risk

Low

Dr. S. Sava

Breast Cancer Risk

Reference

High

Your Current Risk

Medium

Optimum Life and Medical Follow-up Plan Risk

Low

Dr. S. Sava

Colon Cancer Risk

Reference

High

Medium
Your Current Risk

Optimum Life and Medical Follow-up Plan Risk

Low

Dr. S. Sava

Gastric Cancer Risk

Reference

High
Your Current Risk

Optimum Life and Medical Follow-up Plan Risk

Medium

Low

Dr. S. Sava

Osteoporosis Risk
Reference

High

Your Current Risk

Medium

Optimum Life and Medical Follow-up Plan Risk

Low

Dr. S. Sava