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Production During
Exercise
PED 5230
Moderate Aerobic
Energy
• 50-85% of VO2max
Oxygen?
• Fuel?
Lactate?
Moderate Aerobic
Energy
Oxygen Supply =
Oxygen
Demand...barely
Moderate Aerobic
Energy
• Shift towards a greater contribution from
carbohydrates.
Why?
• Advantage?
• Disadvantage?
Muscle
Glucagon
• Catecholamines
• Epinephrine
• Norepinephrine
Moderate Aerobic
Energy
1.0 1.5
Glycogen Depletion
Moderate Aerobic
Energy
• Prolonged exercise
Carbohydrates
• Hypoglycemia
• Glycogen Depletion
• Proteins
Gluconeogenesis
Fat Burns in a Carbohydrate /
Protein Flame low pyruvate
Ketones
Moderate Aerobic
Energy
• Ketones
acetoacetate
• beta-
hydroxybutyrate
• Fuel for ST fibers,
brain and nerves
• Acidic
The Glucose-Alanine Cycle
Moderate Aerobic
Energy
Near lactate threshold
Fatigue
QuickTimeª and a
TIFF (Uncompressed) decompressor
are needed to see this picture.
Fatigue
• ATP or P?
Glycogen depletion?
• > 1-2 hours
QuickTimeª and a
TIFF (Uncompressed) decompressor
are needed to see this picture.
• Hypoglycemia?
Direct - muscle
• Indirect - CNS
Hypoglycemia
Hypoglycemia
Brain
(inhibit)
O2
Heart Muscles
Glycogen & Fat
low glucose
Liver Adipose
Glycogen Fat
Fatigue
• Lactic acid or H?
QuickTimeª and a
TIFF (Uncompressed) decompressor
are needed to see this picture.
Lungs O2
Heart O2 Muscles
Glycogen & Fat
Liver Adipose
Fat
Glycogen
Oxygen / Lactic
Acid
Fatigue
• Central fatigue?
• Central governor
Central Fatigue
Brain
(inhibit)
Lungs O2
Heart O2 Muscles
Glycogen & Fat
Liver Adipose
Glycogen Fat
Heavy Aerobic Energy
Oxygen?
• Fuel?
Lactate?
Heavy Aerobic Energy
Muscles
• Heart, too?
Anaerobic energy
Heavy Aerobic Energy
• Fuel
Carbohydrate
• Aerobic
• Anaerobic
• PC?
Heavy Exercise
• Fatigue
Lactic acid?
• CNS?
Heavy Aerobic Energy
Lactate
Heavy Exercise
• If a person were to begin exercising at their
VO2max, how long would they be able to last
at that intensity?
Why?