Fundic glands - Wikipedia, the free encyclopedia

http://en.wikipedia.org/wiki/Fundic_glands

From Wikipedia, the free encyclopedia

The fundus glands (or fundic glands, or gastric glands) are found in the body and fundus of the stomach. They are simple tubes, two or more of which open into a single duct.

Fundic glands

H&E stain of fundic gland polyp showing shortening of the gastric pits with cystic dilatation Latin glandulae gastricae Gray's subject #247 1166 (http://education.yahoo.com/reference/gray/subjects/subject?id=247#p1166)

1 Pathology 2 Types of cells 3 Additional images 4 External links

Fundic gland polyposis is a medical syndrome where the fundus of the stomach develops many polyps.

Location Name Isthmus Mucous neck cells

Description In gastric pits.

Secretion mucus gel layer

Staining Clear

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Fundic glands - Wikipedia, the free encyclopedia

http://en.wikipedia.org/wiki/Fundic_glands

Neck

Between the chief cells and the basement membrane, larger oval cells, which stain deeply with eosin, are found; these cells are studded gastric acid parietal (oxyntic) throughout the tube at intervals, giving it a beaded and intrinsic cells or varicose appearance. These are known as the factor parietal cells or oxyntic cells, and they are connected with the lumen by fine channels which run into their substance. At the point where they open into the duct, which is termed the neck, the epithelium alters, and consists of short columnar or polyhedral, granular pepsinogen, cells, which almost fill the tube, so that the lumen rennin becomes suddenly constricted and is continued down as a very fine channel. They are known as the chief cells or central cells of the glands. G cells are a type of enteroendocrine cell that secrete the hormone gastrin (gastrin promotes the secretion of pepsinogen (by chief cells) and HCl (by parietal cells) and promotes gastric contractions to mix contents).

Acidophilic

Base

chief (zymogenic) cells

Basophilic

Base

enteroendocrine (APUD) cells

hormones

A fundus gland. A. Transverse section of gland.

Layers of stomach wall

gastric+glands (http://www.emedicinehealth.com/script/main/srchcont_dict.asp?src=gastric+glands) at eMedicine Dictionary Histology at OU 50_02 (http://w3.ouhsc.edu/histology/Glass%20slides/50_02.jpg) - "Fundic stomach" Organology at UC Davis Digestive/mammal/stomach4/stomach2 (http://trc.ucdavis.edu/mjguinan/apc100 /modules/Digestive/mammal/stomach4/stomach2.html) - "Mammal, ruminant stomach (LM, High)" Histology at BU 11301ooa (http://www.bu.edu/histology/p/11301ooa.htm) - "Digestive System: Alimentary Canal - fundic stomach"

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Fundic glands - Wikipedia, the free encyclopedia

http://en.wikipedia.org/wiki/Fundic_glands

Veterinary Histology at vt.edu (http://education.vetmed.vt.edu/curriculum/VM8054/Labs/Lab18 /EXAMPLES/Exfndgld.htm) MedEd at Loyola Histo/frames/Histo18.html (http://www.meddean.luc.edu/Lumen/MedEd/Histo/frames /Histo18.html) - see slide #42 This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained within it may be outdated.

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