Laboratory Study (none) DRUG STUDY

Drug

Indication

Date Ordered: 12-09-09 Generic Name: Clozapine Brand Name: Clorazil Classificati on: Antipsychotics Dosage: 100mg 1tab h.s.

Used to schizonphreni a unresponsive to or intolerant of standard therapy with other antipsychotics

Side Effect/Adverse Reaction Binds to Hypotension dopamine Constipation receptors in Sweating the CNS. Also Nausea and has Vomiting anticholinergi Hyperglycemia c and alphaExtrapyramidal adrenergic reactions blocking Sedation activity. Dizziness Produces Dry Mouth fewer Salivation extrapyramind Weight Gain al reactions Fever and less Abdominal tardive Discomfort dyskinesia than standard antipsychotics but carries high risk of hematologic abnormalities.

Action

Nursing Consideration -Monitor the blood pressure and pulse rate before administering the medication -Monitor for signs of myocarditis (unexplained fatigue, dyspnea, tachypnea, fever, chest pain, palpitations). If this occur clozapine should be discontinued and not restarted -Monitor for any possible side effects of tardive dyskinesia.Rep ort this signs immediately, may be irreversible -Monitor for frequency and consistency of bowel movements. Increasing bulk and fluids in the diet may help to minimize constipation -Overdose of this medication is treated with activated charcoal and supportive therapy.

Patient Teachings -Instruct patient to take medication exactly as directed -Inform patient of possibility of extrapyramidal symptoms. Instruct patient to report the symptoms immediately -Advise patient to change positions slowly to minimize orthostatic hypotension -Instruct patient to use frequent mouth rinses, good oral hygiene, and sugarless gum or candy to minimize dry mouth -Instruct patient to notify health care provider promptly if unexplained fatigue, dyspnea, tachypnea, chest pain, palpitations, sore throat, lethargy, weakness and malaise

Drug

Indication

Date Ordered: 12-09-09 Generic Name: Fluphenazine Brand Name: Prolixin Classification: Anti-psychotics Dosage:

Used to treat symptoms of a certain type of mental/mood condition (schizophreni a).

Side Effect/Adverse Reaction Has activity Extrapyramidal at all levels symptoms of (including the central pseudoparkinsonis nervous m, systemas dystonia, well as on dyskinesia, multiple akathisia, organ oculogyric crises, systems. opisthotonos, & The hyperreflexia) mechanism Restlessness whereby Hypotension its therapeut Dry Mouth icaction is Headache exerted is Constipation unknown. Nausea Blurred Vision Tachycardia Nasal Congestion

Action

Nursing Consideration -Monitor for frequency and consistency of bowel movements. Increasing bulk and fluids in the diet may help to minimize constipation -Monitor for any possible side effects of tardive dyskinesia.Repo rt this signs immediately, may be irreversible -Instruct patient to change position slowly from sitting to lying position to prevent dizziness -Encourage patient to drink plenty of water (8-10 glasses a day) -Monitor the Vital signs of patient before and after adminitering the medication

Patient Teachings -Instruct patient to take medication exactly as directed -Inform patient of possibility of extrapyramida l symptoms. Instruct patient to report the symptoms immediately -Instruct patient to use frequent mouth rinses, good oral hygiene, and sugarless gum or candy to minimize dry mouth -Instruct patient not to stop taking this drug suddenly without consulting her doctor. Some conditions may worsen if the medication is suddenly stopped. -Instruct patient to use this medication regularly in order to get the most benefit from it.