Z Drug Facts

Normal Laboratory Values

In the following tables, normal reference values for commonly requested laboratory tests are listed in traditional units and in SI units. The tables are a guideline only. Values are method dependent and normal values may vary between laboratories. Blood, Plasma or Serum Reference Value Determination Ammonia (NH3) - diffusion Ammonia Nitrogen Amylase Anion gap (Na -[Cl + HCO3 ]) (P) Antithrombin III (AT III) Bicarbonate:Arterial Venous Bilirubin: Conjugated (direct) Total Calcitonin Calcium:Total Ionized Carbon dioxide content (plasma) Carcinoembryonic antigen Chloride Coagulation screen: Bleeding time Prothrombin time Partial thromboplastin time (activated) Protein C Protein S Copper, total Corticotropin (ACTH adrenocorticotropic hormone) - 0800 hr Cortisol:0800 hr 1800 hr 2000 hr
+ -

Conventional units 20120 mcg/dl 1545 g/dl 35118 IU/L 716 mEq/L 80120 U/dl 2128 mEq/L 2229 mEq/L e 0.2 mg/dl0.11 mg/dl < 100 pg/ml 8.610.3 mg/dl 4.45.1 mg/dl 2132 mmol/L < 3 ng/ml 95110 mEq/L 39.5 min 1013 sec 2237 sec 0.71.4 /ml 0.71.4 /ml 70160 mcg/dl < 60 pg/ml 530 mcg/dl 215 mcg/dl e 50% of 0800 hr

SI units 1270 mcmol/L 1132 mol/L 0.581.97 mckat/L 716 mmol/L 8001200 U/L 2128 mmol/L 2229 mmol/L e 4 mcmol/L218 mcmol/L < 100 ng/L 2.22.74 mmol/L 11.3 mmol/L 2132 mmol/L < 3 mcg/L 95110 mmol/L 180570 sec 1013 sec 2237 sec 7001400 U/ml 7001400 U/ml 1125 mcmol/L < 13.2 pmol/L 138810 nmol/L 50410 nmol/L e 50% of 0800 hr

Creatine kinase:Female Male Creatinine kinase isoenzymes, MB fraction Creatinine Fibrinogen (coagulation factor I) Follicle-stimulating hormone (FSH): Female Midcycle Male Glucose, fasting Glucose Tolerance Test (Oral) Fasting 60 min 90 min 120 min (K) -Glutamyltransferase (GGT): Male Female Haptoglobin Determination Hematologic tests: Fibrinogen Hematocrit (Hct), female male Hemoglobin A 1C Hemoglobin (Hb), female male Leukocyte count (WBC) Erythrocyte count (RBC), female male Mean corpuscular volume (MCV) Mean corpuscular hemoglobin (MCH) Mean corpuscular hemoglobin concentrate (MCHC) Erythrocyte sedimentation rate (sedrate, ESR) Erythrocyte enzymes: Glucose-6 -phosphate dehydrognase

20170 IU/L 30220 IU/L 012 IU/L 0.51.7 mg/dl 150360 mg/dl 213 mlU/ml 522 mlU/ml 18 mlU/ml 65115 mg/dl mg/dl Normal Diabetic 70105 > 140 120170u 200 100140u 200 70120 u 140 950 units/L 840 units/L 44303 mg/dl Conventional units 200400 mg/dl 36%-44.6% 40.7%-50.3% 5.3%-7.5% of total Hgb 12.115.3 g/dl 13.817.5 g/dl 38009800/mcl 3.55 x 106/mcl 4.35.9 x 106/mcl 8097.6 mcm3 2733 pg/cell 3336 g/dl e30 mm/hr 2505000 units/106

0.332.83 mckat/L 0.53.67 mckat/L 00.2 mckat/L 44150 mcmol/L 1.53.6 g/L 213 IU/L 522 IU/L 18 IU/L 3.66.3 mmol/L mmol/L NormalDiabetic 3.95.8 > 7.8 6.79.4 u 11.1 5.67.8 u 11.1 3.96.7 u 7.8 950 units/L 840 units/L 0.443.03 g/L SI units 24 g/L 0.360.446 fraction of 1 0.40.503 fraction of 1 0.0530.075 121153 g/L 138175 g/L 3.89.8 x 109/L 3.55 x 1012/L 4.35.9 x 1012/L 8097.6 fl 1.662.09 fmol/cell 20.322 mmol/L e 30 mm/hr 2505000 mcunits/cell

Reference Value

(G-6-PD) Ferritin Folic acid: normal Platelet count Reticulocytes Vitamin B12

cells 10383 ng/ml >3.112.4 ng/ml 150450 x 103/mcl 0.5%-1.5% of erythrocytes 2231132 pg/ml 30160 mcg/dl 45160 mcg/dl 220420 mcg/dl 1.27 units/L 14%-26% of total 29%-39% of total 20%-26% of total 8%-16% of total 6%-16% of total 23862 pmol/L 728.1 nmol/L 150450 x 109/L 0.0050.015 165835 pmol/L

Iron:Female Male Iron binding capacity Isocitrate dehydrogenase Isoenzymes Fraction 1 Fraction 2 Fraction 3 Fraction 4 Fraction 5

5.431.3 mcmol/L 8.131.3 mcmol/L 39.475.2 mcmol/L 1.27 units/L 0.140.26 fraction of total 0.290.39 fraction of total 0.200.26 fraction of total 0.080.16 fraction of total 0.060.16 fraction of total 1.674.17 mckat/L 0.72.1 mmol/L e 2.41 mcmol/L 10150 units/L

Lactate dehydrogenase Lactic acid (lactate) Lead Lipase Lipids: Total Cholesterol Desirable Borderline-high High LDL Desirable Borderline-high High HDL (low) Triglycerides Desirable Borderline-high High Very high

100250 IU/L 619 mg/dl e 50 mcg/dl 10150 units/L

< 200 mg/dl 200239 mg/dl > 239 mg/dl < 130 mg/dl 130159 mg/dl > 159 mg/dl < 35 mg/dl < 200 mg/dl 200400 mg/dl 4001000 mg/dl > 1000 mg/dl

< 5.2 mmol/L < 5.26.2 mmol/L > 6.2 mmol/L < 3.36 mmol/L 3.364.11 mmol/L > 4.11 mmol/L < 0.91 mmol/L < 2.26 mmol/L 2.264.52 mmol/L 4.5211.3 mmol/L > 11.3 mmol/L

Magnesium Osmolality Oxygen saturation (arterial) PCO2, arterial pH, arterial Determination PO2, arterial: Breathing room air1 On 100% O2 Phosphatase (acid), total at 37C Phosphatase alkaline2 Phosphorus, inorganic,3 (phosphate) Potassium Progesterone Female Follicular phase Luteal phase Male Prolactin Prostate specific antigen Protein: Total Albumin Globulin Rheumatoid factor Sodium Testosterone: Female Male Thyroid Hormone Function Tests: Thyroid-stimulating hormone (TSH) Thyroxine-binding globulin capacity Total triiodothyronine (T3) Total thyroxine by RIA (T4) T3 resin uptake Transaminase, AST (aspartate aminotransferase, SGOT) Transaminase, ALT (alanine aminotransferase, SGPT)

1.32.2 mEq/L 280300 mOsm/kg 94%-100% 3545 mm Hg 7.357.45 Conventional units 80105 mm Hg > 500 mm Hg 0.130.63 IU/L 20130 IU/L 2.55 mg/dl 3.55 mEq/L 0.11.5 ng/ml 0.11.5 ng/ml 2.528 ng/ml < 0.5 ng/ml 1.424.2 ng/ml 04 ng/ml 68 g/dl 3.65 g/dl 2.33.5 g/dl < 60 IU/ml 135147 mEq/L 686 ng/dl 2701070 ng/dl 0.356.2 mcU/ml 1026 mcg/dl 75220 ng/dl 411 mcg/dl 25%-38% 1147 IU/L 753 IU/L

0.651.1 mmol/L 280300 mmol/kg 0.94 - fraction of 1 4.76 kPa 7.357.45 SI units 10.614 kPa 2.210.5 IU/L or 2.210.5 mckat/L 20130 IU/L or 0.332.17 mckat/L 0.81.6 mmol/L 3.55 mmol/L 0.324.8 nmol/L 0.324.8 nmol/L 889 nmol/L < 1.6 nmol/L 1.424.2 mcg/L 04 ng/ml 6080 g/L 3650 g/L 2335 g/L < 60 kIU/L 135147 mmol/L 0.213 nmol/L 9.337 nmol/L 0.356.2 mU/L 100260 mcg/L 1.23.4 nmol/L 51142 nmol/L 0.250.38 fraction of 1 0.180.78 mckat/L 0.120.88 mckat/L

Reference Value

Transferrin Urea nitrogen (BUN) Uric acid Vitamin A (retinol) Zinc

1 2

220400 mg/dL 825 mg/dl 38 mg/dl 1560 mcg/dl 50150 mcg/dl

2.204.00 g/L 2.98.9 mmol/L 179476 mcmol/L 0.522.09 mcmol/L 7.723 mcmol/L

Age dependent Infants and adolescents up to 104 U/L 3 Infants in the first year up to 6 mg/dl

Urine Reference Value Determination Calcium1 Catecholamines: Epinephrine Norepinephrine Catecholamines, 24-hr Copper1 Creatinine: Child Adolescent Female Male pH Phosphate Protein Total At rest Protein, quantitative Sodium
1 1

Conventional units 50250 mcg/day < 20 mcg/day < 100 mcg/day < 110 g 1560 mcg/day 822 mg/kg 830 mg/kg 0.61.5 g/day 0.81.8 g/day 4.58 0.91.3 g/day 25100 mEq/day 114 mg/dL 5080 mg/day < 150 mg/day 100250 mEq/day 1.0021.030 250750 mg

SI units 1.256.25 mmol/day < 109 nmol/day < 590 nmol/day < 650 nmol 0.240.95 mcmol/day 71195 mol/kg 71265 mol/kg 5.313.3 mmol/day 7.115.9 mmol/day 4.58 2942 mmol/day 25100 mmol/day 10140 mg/L 5080 mg/day < 0.15 g/day 100250 mmol/day 1.0021.030 1.484.43 mmol

Potassium1

Specific gravity, random Uric acid, 24-hr

1

Diet dependent.

Drug Levels* Reference Value Drug Determination Aminoglycosides Amikacin Conventional units 18 mcg/ml SI units 2030 mcg/ml

(trough) (peak) Gentamicin (trough) (peak) Kanamycin (trough) (peak) Netilimicin (trough) (peak) Streptomycin (trough) (peak) Tobramycin (trough) (peak) Drug Determination Amiodarone Bretylium Digitoxin Digoxin Disopyramide Flecainide Antiarrhythmics Lidocaine Mexiletine Procainamide Propranolol Quinidine Tocainide Verapamil Carbamazepine Phenobarbital Anticonvulsants Phenytoin Primidone Valproic Acid

1.713.7 mcmol/L

3451 mcmol/L

0.52 mcg/ml 610 mcg/ml 510 mcg/ml 2025 mcg/ml 0.52 mcg/ml 610 mcg/ml < 5 mcg/ml 520 mcg/ml 0.52 mcg/ml 520 mcg/ml Conventional units 0.52.5 mcg/ml 0.51.5 mcg/ml 925 mcg/L 0.82 ng/ml 28 mcg/ml 0.21 mcg/ml 1.56 mcg/ml 0.52 mcg/ml 48 mcg/ml 50200 ng/ml 26 mcg/ml 410 mcg/ml 0.080.3 mcg/ml 412 mcg/ml 1040 mcg/ml 1020 mcg/ml 412 mcg/ml 40100 mcg/ml

14.2 mcmol/L 12.520.9 mcmol/L nd1 nd nd nd nd nd 1.14.3 mcmol/L 12.821.8 mcmol/L SI units 1.54 mcmol/L nd 11.832.8 nmol/L 0.92.5 nmol/L 618 mcmol/L nd 4.521.5 mcmol/L nd 1734 mcmol/ml 190770 nmol/L 4.69.2 mcmol/L nd nd 1751 mcmol/L 43172 mcmol/L 4080 mcmol/L 1855 mcmol/L 280700 mcmol/L

Reference Value

Amitriptyline Amoxapine Bupropion Clomipramine Desipramine Antidepressants Doxepin Imipramine Maprotiline Nortriptyline Protriptyline Trazodone Chlorpromazine Fluphenazine Antipsychotics Haloperidol Perphenazine Thiothixene Drug Determination Amantadine Amrinone Chloramphenicol Cyclosporine3

110250 ng/ml2 200500 ng/ml 25100 ng/ml 80100 ng/ml 115300 ng/ml 110250 ng/ml 225350 ng/ml 50150 ng/ml 70250 ng/ml 8001600 ng/ml 50300 ng/ml 0.132.8 ng/ml 520 ng/ml 0.81.2 ng/ml 257 ng/ml Reference Value Conventional units 300 ng/ml 3.7 mcg/ml 1020 mcg/ml 250800 ng/ml (whole blood, RIA) 50300 ng/ml (plasma, RIA) 0 mg/dl 100 ng/ml 0.61.2 mEq/L 100300 mg/L 515 mg/dl 0.54.1 ng/ml 1020 mcg/ml 515 ng/ml 2040 mcg/ml
2 2

500900 nmol/L nd nd nd nd nd nd nd nd nd nd 150950 nmol/L nd nd nd nd SI units nd nd 3162 mcmol/L nd nd 0 mmol/L nd 0.61.2 mmol/L 7242172 mcmol/L nd nd 55110 mcmol/L nd nd

200300 ng/ml

Ethanol4 Hydralazine Miscellaneous Lithium Salicylate Sulfonamide Terbutaline Theophylline Vancomycin (trough) (peak)

* The values given are generally accepted as desirable for treatment without toxicity for most patients. However, exceptions are not uncommon.

1 2

nd = No data available. Parent drug plus N-desmethyl metabolite. 3 24hour trough values. 4 Toxic: 50100 mg/dl (10.921.7 mmol/L).

The following table is adopted from the Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, National Institutes of Health. Classification of Blood Pressure* Category Optimal1 Normal High-normal Hypertension2 Stage 1 Stage 2 Stage 3 < 120 < 130 130139 140159 160179 u 180 Reference value Systolic (mm Hg) and and or or or or Diastolic (mm Hg) < 80 < 85 8589 9099 100109 u 110

* For adults age 18 and older who are not taking antihypertensive drugs and not acutely ill. When systolic and diastolic blood pressures fall into different categories, the higher category should be selected to classify the individual's blood pressure status. In addition to classifying stages of hypertension on the basis of average blood pressure levels, clinicians should specify presence or absence of target organ disease and additional risk factors. 1 Optimal blood pressure with respect to cardiovascular risk is below 120/88 m Hg. However, unusually low readings should be evaluated for clinical significance. 2 Based on the average of two or more readings taken at each of two or more visits after an initial screening. Books@Ovid Copyright 2003 Facts and Comparisons David S. Tatro A to Z Drug Facts