CURRICULUM VITAE

DIMITRI NOVITZKY, MD, FCS, PhD. FACC.

DIRECTOR OF RESEARCH AT TAMPA TRANSPLANT INSTITUTE

Address: Office a" 5 Tampa General Circle

Suite 650, Tampa FL 33606

Cell: (813) 503-3991

Home: (813) 837-2084

PERSONAL DATA

Dimitri Novitzky

Date of Birth: March 18, 1946

Place of Birth: Paris, France
Citizenship: United States of America
Stella Maris Novitzky (wife) DOB: September 18, 1947
Michael Novitzky (son) DOB: May 25, 1980
Peter Novitzky (son) DOB: January 15, 1983
Alexei Novitzky (son) DOB: March 11, 1984

Revised: December, 2009

POST GRADUATE TRAINING

M.D. Degree: La Plata School of Medicine, La Plata, Buenos Aires, Argentina, gr

aduated in 1969.
Rotating Internship: July 1969 to June 1970, La Plata, Buenos Aires, Argentina.
Straight Surgical Intern: June 15, 1970 to June 14, 1971, Vancouver General Hos
pital, Vancouver, Canada (University of British Columbia).
Resident in General Surgery: July 1, 1971, to June 30, 1972, Vancouver General
Hospital (University of British Columbia).
Tutor in Anatomy: October 1972 to June 1973, University of La Plata Medical Sch
ool, Buenos Aires, Argentina.
Resident in Surgery: June 1973, to April 30, 1974, Hospital Regional, Comodoro
Rivadavia, Argentina.
Chief Resident in General Surgery: May 1, 1974 to April 30, 1975, Hospital Regi
onal, Comodoro 0Rivadavia, Argentina.
Full-time Specialist in General Surgery: May 1, 1975 to December 15, 1976, Hosp
ital Regional, Comodoro Rivadavia, Argentina.
Resident in Cardiothoracic Surgery: January 1, 1977 to December 30, 1977, Natio
nal and Pelonomi Hospitals, Republic of South Africa (University of the Orange F
ree State)
Resident in Cardiac Surgery: February 1, 1978 to August 31, 1981, Groote Schuur
Hospital and Red Cross War Memorial Children's Hospital, Republic of South Afri
ca (University of Cape Town). The training at the University of the Orange Free
State was a combined program of cardiac and thoracic surgery, supervised by Pro
fessor Johannes Meyer. During the training at the University of Cape Town, six
months were dedicated to thoracic surgery and the remaining time to cardiovascul
ar surgery. This was directly supervised by Professor Christiaan N. Barnard.
In 1981, I was appointed specialist in cardiac surgery at Groote Schuur Hospital
and Red Cross War Memorial Children's Hospital in Cape Town, South Africa. Thi
s appointment was held until January 1987. During this period, I was actively i
nvolved in adult and pediatric cardiac surgery, with main emphasis in the field
of heart transplantation. Part of my duties included the training of residents,
participation in ward rounds, tutorials, and supervising a group of researchers
studying of the effects of brain-death on the heart and its effects on the meta
bolism of the body as a whole.
From February 4, 1987, until October 1990, I was a member of the heart transplan
tation team at the Oklahoma Transplantation Institute, Baptist Medical Center, O
klahoma City, Oklahoma.
Since November 1990, I have been working as an Associate Professor at the Univer
sity of South Florida in the Department of Cardiothoracic Surgery in Tampa, Flor
ida.
As of July 1998, I have been promoted and received tenure as a full Professor at
the University of South Florida in the Department of Cardiothoracic Surgery in
Tampa, Florida.

DEGREES

Graduated as a medical doctor from the La Plata School of Medicine, La Plata, Bu

enos Aires, Argentina, June 1969.
ECFMG: February 1970
FLEX: December 1990
Fellow of the Argentine College of Surgeons registered as specialist in General
Surgery: 1975 (by examination)
Fellow of the College of Medicine of South Africa registered as a specialist in
Cardiothoracic Surgery (FCS) with the South African Medical and Dental Council:
1982 (by examination)
PhD from the University from Cape Town June 2008, for the development of the sci
entific management of the brain dead organ donor (Hormonal Therapy)
DISSERTATION

1. PhD for the dissertation submitted to the University of Cape Town aPathophysi
ological Effects of Brain Death on Potential Donor Organs, and the Introduction
of a New Method of Donor Management. June 2008
2. Patent in development. USF patenting office has approved the concept of hi
gh dose Esmolol administration during cardiopulmonary bypass in patients with
high risk for surgery. The FDA a" IND application as well as the IRB protocol a
re in progress. 2007

PROFESSIONAL LICENSURE

Argentine College of Medicine 1969

Argentine College of Surgeons 1975
South African Medical and Dental Council 1982
Specialist in Cardiothoracic Surgery 1982
Oklahoma State Board of Medical Examiners 1985
Specialist in Cardiothoracic Surgery
License #15634
Florida Teaching Certificate 1991
License #ME 0061367

LANGUAGES
I am fluent in reading, writing and speaking in English, Spanish and Russian.

AWARDS AND PRIZES

President's Award of the International Society for Heart Transplantation for the
paper: "Electrocardiographic, hemodynamic and endocrine changes occurring durin
g experimental brain-death in the Chacma baboon", in collaboration with W. Wicom
b, A. Rose, R. Fraser, D. Cooper, and C.N. Barnard, 1984.
First prizewinner for the presentation of the poster entitled "Diagnosis of acut
e cardiac rejection using radio nuclide scanning techniques", presented at the b
iannual meeting of the South African Cardiac Society with the participation of P
rofessor M. Iturralde, 1986.

SCHOLARSHIPS
During my medical training, I was initially a junior tutor of anatomy, and after
graduation during the rotating internship, I became a lecturer of anatomy with
the Anatomy Department, La Plata Medical School, Buenos Aires, Argentina, 1965-1
970.

CLINICAL WORK

During the years of training in general surgery, I was exposed to all surgical s
pecialties on a rotation basis during the first two years.
As Chief Resident, I was in charge of the Department of General Surgery, being r
esponsible for all the emergency operations and permanently on call for trauma c
alls. During this year, I performed all -types of major general surgical proced
ures.
As Resident in Cardiothoracic Surgery, I was guided by Professor C.N. Barnard in
the field of cardiovascular surgery. My primary responsibilities were initiall
y in the care of patients and, during the last two years, performing all types o
f adult cardiac operations and pediatric cardiac surgery.
From the beginning, my duty was especially dedicated to the care of donors for h
eart transplantation. After one year, I took over the post-operative management
of patients who had undergone a heart transplant.

I performed my first heterotopic heart transplant as a fellow at Groote Schuur H

ospital.
In September 1982, I was appointed by Professor C.N. Barnard as a specialist in
charge of the Heart Transplant Unit and full-time Fellow at the Cardiac Research
Laboratory for one year. During that period, I developed a non-invasive techni
que for the diagnosis of acute cardiac rejection using radionuclide-scanning met
hods, first in animals and then afterwards applied the technique to human cardia
c transplantation, which was widely used at the University of Cape Town.
From January 1984 to the present, I have continued my research activities. At t
he Heart Transplant Unit in Cape Town, I worked approximately 50% in the laborat
ory where I embarked on the experimental study of brain-death in baboons and pig
s looking at the effects on the myocardium and the hemodynamic and endocrine det
erioration following brain-death. The metabolic studies in brain-dead animals a
nd patients confirmed that aerobic metabolism is inhibited. Explaining one of t
he mechanisms participating in the graft dysfunction after organ transplantation
.
Based on this work, I developed the "hormonal therapy for brain-dead organ donor
s", showing its beneficial effect.
As a result of this research, I found that by administering Triiodothyronine (T3
), the metabolic dysfunction is fully corrected prior to organ transplantation.
Currently, this therapeutic modality is used widely in the rescue of unstable b
rain-dead organ donors.
Together with Dr. W.N. Wicomb, I was involved in myocardial preservation in a po
rtable unit, achieving successful preservation of the myocardium over a period o
f 48 hours, followed by orthotopic transplantation of the hearts of Chacma baboo
ns with excellent survival of the animals.
In immunosuppressed Chacma baboons, I performed using cardiopulmonary bypass, an
en bloc heart and lung transplantation finding that the lungs are actively reje
cted while minimal histological changes occur in the transplanted hearts. This
is in contraindication to previous reports in which it was stated that the heart
and lungs are rejected simultaneously. This work was published in the Annals o
f Thoracic Surgery.
In September 1982, I was in charge of the Department of Heart Transplantation, w
orking in close collaboration with Professor Christiaan N. Barnard, and later wi
th B. Reichart and D.K.C. Cooper, performing personally a total of 55 heart tran
splants, of which 8 were retransplantations (1 for irreversible acute rejection
and 7 were for chronic rejection). In 2 patients, the recipient heart was resec
ted (previous
heteroptoic heart transplants), and a heart was implanted in orthotopic position
, leaving these patients with two transplanted hearts. During this period, 12 h
eart and lung transplants were performed in Groote Schuur Hospital, in which I p
articipated actively in the surgical procedures, resecting the donor heart and l
ung block and performing a heart and lung transplant in a patient with primary p
ulmonary hypertension.

In 1987, as a member of the Oklahoma Transplantation Institute, I became co-dire

ctor of research and director or organ procurement. While in this position, I h
ave been involved in 77 procedures, including heart and heart-lung transplants.
From 1990 to December 1995, I held the title of Acting Chief of Cardiothoracic S
urgery at the James A. Haley Veterans' Hospital. On January 1, 1996, I became t
he formal Chief of Cardiothoracic Surgery performing the majority of open heart
surgeries. I am also involved in Thoracic Surgery coverage whenever required an
d provide surgical stand by for all PTCA elective or emergent.
At Tampa General Hospital, Tampa, Florida, I am a member of the Heart Transplant
Team. I perform open heart surgery and provide coverage for the Thoracic Traum
a Service.
From July to present, I have performed over 1,000 total myocardial revasculariza
tions not using the heart-lung machine. This is a new re-introduction of old te
chnology. However, with the advent of beta-blockers and special retractors, I a
m able to do a coronary bypass on any epicardial artery. This technique has bee
n performed only in one other institution in the United States.

APPOINTMENTS

Professor, Department of Cardiothoracic Surgery, University of South Florida, Ta

mpa, Florida, August 1998 to March 30 2009.
Cardiothoracic Surgeon, Surgical Service, James A. Haley Veterans' Hospital, Tam
pa, Florida.
Acting Chief, Cardiothoracic Surgery, Surgical Service, James A. Haley Veterans'
Hospital, Tampa, Florida, 1990-1995.
Chief, Cardiothoracic Surgery, Surgical Service, James A. Haley Veterans' Hospit
al, Tampa, Florida, January 1996 to January 2001.
Cardiothoracic Surgeon, Department of Surgery, H. Lee Moffitt Cancer Center, Tam
pa, Florida.
Council Member of the American Society of Transplant Surgeons, Thoracic Organ Tr
ansplantation Section, Chicago, Illinois.
Director Transplant Research at Tampa Transplant Institute, from October 1st, 20
09 to date

PREVIOUS RESEARCH

The potential applications of Triiodothyronine therapy following acute myocardia

l ischemic events were further examined in conditions exhibiting the euthyroid s
ick syndrome.
Experimental work was performed at the Veterinary School at the Oklahoma State U
niversity in Stillwater and the Oklahoma Medical Research Foundation. The main
emphasis of this research was to examine the effects of Triiodothyronine in the
reversal of myocardial dysfunction in the following conditions: 1) stunned Myoc
ardium, 2) recovery of the cardiac function following catecholamine infusion, an
d 3) myocardial depression following cardiopulmonary bypass.
Currently, we are looking at the effect of T3 pretreatment in rats with heart fa
ilure, observing a significant cardiac recovery and response to beta agonists.
Control rats, after six weeks of heart failure, no longer respond to beta agonis
ts. This may become of relevance mainly in open heart surgery or following PTCA
's.
I have been acting as a Consult to SmithKline Beecham Pharmaceuticals for the de
velopment of protocols related to T3 in experimental and clinical applications i
n non-thyroid diseases.
The FDA has issued an IND number for the use of T3 in non-thyroid diseases. A r
andomized blinded study was done in Oklahoma in patients undergoing coronary art
ery grafts on cardiopulmonary bypass.
Recently, a fully funded study has been completed (Protocol TS-107). In this st
udy using transesophageal echocardiography, we examined the effects of T3 in pat
ients undergoing open heart surgery in a randomized, prospective blinded study.
This was done in collaboration with Dr. Hector Fontanet (Cardiology Department)
.
We administered open T3 to high-risk heart patients with an estimated mortality
of 15-50%, (using a mathematical model developed by Dr. Parsonnet from Beth Isra
el Hospital, New Jersey), observing a significant death rate reduction by 60%.
At the James A. Haley Veterans' Hospital, I was the Primary Investigator for a V
A Cooperative Study entitled, "Urgent Revascularization in Unstable Angina".
In addition, I was Co-Investigator in the following research protocols:
1) Leukocyte & Platelet Activation During Cardiac Bypass
Surgery: Phase II
2) Staging of Non-Small Cell Lung Carcinoma by Diagnostic
Imaging with Immuraid CEA
3) Diagnosis of Myocardial Viability: Outcomes and Costs in
Chronic Heart Disease
4) What is the Effect of Increasing F102 on the Distribution of Alveolar Ven
tilation and Perfusion in Patients After Cardiac Operations?
5) Can Dobutamine Stress Echocardiography Predict Recovery of
Contractile Function of Viable Myocardium?
I was a Primary Investigator at the Baptist Medical Center for the use of the "T
horatec" ventricular assist device for the rescue of the myocardium following op
en heart surgery and as a bridge to transplantation. I implanted the device in a
patient who survived 70 days with its support (one of the longest ventricular a
ssist device supported patients in the USA), and was thereafter successfully tra
nsplanted.

CURRENT CLINICAL RESEARCH

I am Co-Chairman with Dr. Fred Grover on a VA grant (10.6 million dollars) for a
cooperative study aOutcomes Following Myocardial Revascularization: On and Off
Cardiopulmonary Bypassa, which was performed in 18 Veteran Medical Centers.
We have completed the randomization and one year follow up for the Cooperative s
tudy CSP 517. Preparation of the main manuscript on the study findings has been
initiated.
I am the senior author of the primary manuscript of the study CSP 517 entitled:
Outcomes Following Non-Emergent Coronary Artery Bypass Graft Procedures:
Revascularization Off versus On Bypass (ROOBY) Trial Findings. NEJM
Multiple manuscripts will follow the primary paper, I estimate that at least twe
nty relevant papers will be published in prestigious journals and multiple meet
ing presentations will follow.
Also, I am reviewer for selected articles for the following journals: 1) Annals
of Thoracic Surgery, 2) Transplantation, and 3) The Journal of heart and Lung Tr
ansplantation.

MEMBERSHIP IN MEDICAL SOCIETIES

1984 - International Society for Heart and Lung Transplantation

1987 - Fellow of the American College of Cardiology (F.A.C.C.)
1990 - The American Society of Transplant Surgeons
1992 - The Society of Organ Sharing
 1993 - American Medical Association
1993 - Florida Medical Association
1993 - The Society of Thoracic Surgeons
1994 - Hillsborough County Medical Association
1994 - Association of VA Surgeons
1995 - Florida Physicians Association
1996 - Florida Society of Thoracic & Cardiovascular Surgeons
2001 - Honorary Member: The Argentinean Cardiothoracic Surgical Society
2007 - Member of Editorial Board of Argentinean Journal of CT Surgery

External examiner of a dissertation for a PhD degree, University of Oslo: Safe i

ntroduction of myocardial revascularization without cardiopulmonary bypass.
January 2010.

PRESENTATIONS AT MAJOR MEETINGS

1. NOVITZKY, HELLMAN, COOPER, HASSOULAS, BARNARD, ITURRALDE Radionuclide assessm

ent of heteroptoic heart transplants. Presented to the South African Cardiac So
ciety, September 1982.
2. COOPER, WICOMB, BOYDT, LANZA, NOVITZKY, HASSOULAS, BARNARD. Orthotopic and h
eteroptoic heart transplantation: Aspects of the Cape Town experience. Present
ed to the Transplantation Society, Brighton 1982.
3. NOVITZKY, WICOMB, COOPER, ROSE, FRASER, BARNARD. Presidentas Award: Presente
d to the International Society for Heart Transplantation, 1984.
4. NOVITZKY, COOPER, WICOMB, REICHART. Hemodynamic changes, myocardial injury,
and pulmonary edema induced by Sympathetic activity during the development of br
ain-death in the baboon. Presented to a Symposium on Organ Procurement, Detroit
1985.
5. NOVITZKY, COOPER, WICOMB, REICHART. Improved function of stored hearts foll
owing hormonal therapy after brain-death in pigs. Presented to the European Soc
iety for Organ Transplantation, Munich 1985.
6. NOVITZKY, COOPER, WICOMB, REICHART. Brain-death induced hemodynamic changes
resulting in cardiac and pulmonary injury in the baboon. Paper presented to the
European Society for Organ Transplantation, Munich 1985.
7. NOVITZKY D, WICOMB WN, COOPER DKC, REICHART B. Evidence of myocardial and re
nal function recovery following hormonal treatment after brain-death. Presented
to the Southern African Transplantation Society, Ceres 1985, and to a Symposiu
m on Organ Procurement, Detroit 1985.
8. NOVITZKY D. Presented a new approach in the management of brain-dead organ d
onors at Hospital Broussais, Cardiovascular Surgery Department, Paris, France 19
85.
9. NOVITZKY D, ROSE AG, COOPER DKC, REICHART B. Histopathologic changes at the
site of endomyocardial biopsy: Potential for confusion with acute rejection. P
oster presented to the International Society for Heart Transplantation, New York
1986.
10. NOVITZKY D. Speaker at the Lisbon Transplant Society Annual Meeting on aThe
Cape Town Experience of Heart Transplantationa, 1986.
11. NOVITZKY D, COOPER DKC, REICHART B. The values of hormonal therapy in impro
ving organ viability in the transplant donor. Presented to the Transplantation
Society, Helsinki, and to the Society of Thoracic and Cardiovascular Surgeons
of Great Britain and Ireland, Edinburgh 1986.
12. BECERRA E, COOPER DKC, NOVITZKY D, REICHART B. Are there indications for et
eroptoic heart transplantations today? Presented to the Transplantation Society
, Helsinki, and to the Society of Thoracic and Cardiovascular Surgeons of Great
Britain and Ireland, Edinburgh 1986.
13. NOVITZKY D, COOPER DKC, BRINK J. REICHART B. Sequential second and third he
art transplants in patients with previous heterotopic heart allografts. Presen
ted to the South African Cardiac Society, Sun City 1986.
14. NOVITZKY D, COOPER DKC, MORRELL D, ISAACS S. Brain-death, triiodothyronine
(T3) depletion, and inhibition of oxidative phosphorylation-relevance to managem
ent of organ donors. Presented to the European Society for organ transplantatio
n, Gothenburg 1987.
15. REICHART BA, NOVITZKY D, COOPER DKC, CUNNINGHAM MS, ROSE AG. Successful ort
hotopic heart-lung transplantation in the baboon after 5 hours cold ischemia wit
h cardioplegia and Collinsa solution. Presented to the International Society fo
r Heart Transplantation, New York 1986, and Southern African Transplantation So
ciety, Berg-en-Dal 1987.
16. REICHART BA, HUMAN PA, ROSE AG, NOVITZKY D, COOPER DKC. Is pulmonary ischem
ia a factor in the reperfusion response? An experimental study in the Chacma ba
boon. Presented to the International Society for Heart Transplantation, New Or
leans 1987, and Southern African Transplantation Society, Berg-en-Dal 1987.
17. NOVITZKY D, COOPER DKC, ZUDHI H. The physiological management of cardiac t
ransplant donors and recipients using triiodothyronine (T3). Presented as a pos
ter at an International Organ Transplant Forum in honor of Dr. T.E. Starzl, Pitt
sburgh 1987.
18. NOVITZKY D, COOPER DKC, WICOMB WN. Pathophysiology of brain-death in the ex
perimental animal - extracranial aspects: Endocrine changes and metabolic resp
onses. Presented at the Fourth Annual Christiaan N. Barnard Symposium, Oklahoma
City 1987.
19. NOVITZKY D, COOPER DKC. Hormonal therapy of the potential donor: Results o
f hormonal herapy in human brain-dead potential organ donors. Presented at the
 Fourth Annual Christiaan N. Barnard Symposium, Oklahoma City 1987.
20. NOVITZKY D, COOPER DKC, ZUHDI N. Hormonal therapy to the cardiac recipient:
Triiodothyronine therapy in the cardiac transplant recipient. Presented at the
Fourth AnnualChristiaan N. Barnard Symposium, Oklahoma City 1987.
21. NOVITZKY D, COOPER DKC. The value of triiodothyronine (T3) in the rescue of
a failing heart following valve replacement. Presented to the Society of Thora
cic Surgeons at the 23rd Annual Meeting, Toronto, Canada 1987.
22. REICHART B, REICHENSPURNER H, ODELL JA, COOPER DKC, NOVITZKY D, ROSE AG, KLI
NNER W. Initial experience in heart and lung transplantation. Presented at the
Annual Symposium of the Texas Heart Institute, October 1987.
23. REICHENSPURNER H, ODELL JA, COOPER DKC, NOVITZKY D, HUMAN PA, BARNARD CN, RE
ICHART B. Twenty years of heart transplantation at Cape Town University. Prese
nted at the Annual Symposium of the Texas Heart Institute, October 1987.
24. NOVITZKY D, COOPER DKC, BARTON C, GREER A, CHAFFIN J, ZUHDI N. Triiodothyron
ine (T3) as an inotropic agent following open heart surgery. Presented at the C
. Walton Lillehei Surgical Symposium, Minneapolis 1988.
25. NOVITZKY D, COOPER DKC, HUMAN PA, REICHART B, ZUHDI N. Triiodothyronine the
rapy for heart donor and recipient. Presented to the International Society for
Heart Transplantation, Los Angeles 1988.
26. NOVITZKY D, HORAK A, COOPER DKC, ROSE AG. Electrocardiographic and histopat
hologic changes developing during experimental brain-death in the baboon. Prese
nted as a poster to the Transplantation Society, Sydney 1988.
27. COLLINS GM, WICOMB WN, NOVITZKY D, COOPER DKC, HILL JD. Early extranuclear
effect of triiodothyronine (T3) on tissue slices: Relevance to organ donor viab
ility. Presented as a poster to the Transplantation Society, Sydney 1988.
28. NOVITZKY D, COOPER DKC, CHAFFIN JS, GREER AE, DEBAULT LE, ZUHDI N. Improved
cardiac allograft function following triiodothyronine (T3) therapy to both dono
r and recipient. Presented to the American Society of Transplant Surgeons, Chica
go 1989.
29. NOVITZKY D. Case presentations on: (I) prolonged bi-ventricular assist sup
port as a bridge to transplantation, and (ii) bi-ventricular assist device used
in the successful rescue of a transplanted heart, Thoratec Assist Device Investi
gatoras Meeting, Boston 1989.
30. NOVITZKY D. Presented aNew trends and strategies in the management and diag
nosis of acute cardiac rejectiona to the International Society for Heart Transpl
antation, Colorado Springs 1989.
31. NOVITZKY D. Presented (I) the euthyroid sick syndrome, facts, and fallacies
on triiodothyronine replacement therapy, and (ii) experimental and early clinic
al application of triiodothyronine following cardiopulmonary bypass, Oklahoma M
edical ll Research Foundation, National Institutes of Health raining Grant Meeti
ng, 1989.
32. NOVITZKY D. The Euthyroid sick syndrome and Triiodothyronine and the revers
al of myocardial dysfunction. Presented at Grand Rounds, University of South Fl
orida, April 15, 1991.
33. NOVITZKY D. Triiodothyronine therapy and reversal of renal graft dysfunctio
n following brain death and dopamine support. Abstract submitted at the Interna
tional Symposium on Acute Renal Failure, continuing Education Center, Universit
y of North Carolina at Chapel Hill, Chapel Hill, North Carolina, October 2-4, 19
91.
34. NOVITZKY D. Euthyroid sick syndrome, brain-death and donor organ quality -
evidence for the benefit of hormonal therapy in organ donor management. Abstrac
t submitted at the Fifth International Symposium, Endocrinology in Anesthesia an
d Critical Care Medicine, October 15-26, 1991, Berlin, Germany.
35. NOVITZKY D. Cardiopulmonary bypass, myocardial dysfunction, reversal by iod
othyronine therapy. Presented at Grand Rounds, University of South Florida, De
partment of Surgery, November 18, 1991.
36. NOVITZKY D. Current world-wide results of thoracic transplantation. Present
ed at Groote Schuur Hospital, Cape Town, South Africa in commemoration of the 25
th Anniversary of the first human heart transplant, 1992.
37. NOVITZKY D. Cardiac implications of brain-death. Presented at Florida Hosp
ital Translife, Orlando 1992.

38. NOVITZKY D. Presented a poster entitled, aThe impact of Triiodothyronine (T

3) therapy in high risk patients undergoing open heart surgery, at the 15h Annua
l Meeting of the Society of Cardiovascular Anesthesiologists, San Diego, April 2
7, 1993.
39. NOVITZKY D. The surgical aspects of intrathoracic organ transplantation. P
resented at TheFavaloro Foundation, Buenos Aires, Argentina, June 11, 1993.
40. NOVITZKY D. Hormonal Therapy in Cardiac Surgery. Honorary Lecture at III I
nternational Symposium on Heart Transplantation, Cordoba, Spain, May 13-14, 1994
.
41. MCKEOWN P, CONANT P, NOVITZKY D, CINTRON G, FONTANET H. Surgical management
of thrombosed single A-V valve. GSM, Royal Australasian College of Surgeons,
May 1994.
42. NOVITZKY D, FONTANET H, SNYDER M, COBLIO N, MCKEOWN P, SMITH D, PARSONNET V.
The impact of Triiodothyronine (T3) Therapy in the Survival of High Risk Patien
ts Undergoing Open Heart Surgery. Paper presented at The Western Thoracic Surgi
cal Association, Squaw Creek, California, June 22-25, 1994.
43. NOVITZKY D. Presentation at the 75th Annual Meeting of the American Associa
tion of Thoracic Surgeons, Boston, Mass., April 23-26, 1995.
44. NOVITZKY D, FONTANET H, SMITH D, COLBIO N. The Role of Triiodothyronine in
High Risk patients Undergoing Open Heart Surgery. Presented during the plenary
session of the 19th Annual Association of VA Surgeons Meeting in Pittsburgh, Pe
nnsylvania, April 30 - May 3, 1995.
45. NOVITZKY D, FONTANET H, SMITH D, COBLIO N. Improving Efficiency in Cardiac
Surgery Practice. A joint conference with the Department of Veterans Affairs Of
fice of Quality Management and the Cardiac Surgery Consultants Committee of the
VACO Surgical Service, Keystone, Colorado, August 24-26, 1995.
46. NOVITZKY D, FONTANET H, SMITH D, COBLIO N. aNovel Actions of Thyroid Hormon
ea, at the International Endocrinology Congress, Toronto, Canada, September 10,
1995.
47. NOVITZKY D. aManagement of the High Risk Cardiac Surgery Patient and Surgic
al Alternatives in the Technically Difficult Patienta, Cardiovascular Symposium
in Ponce, Puerto Rico, September 22-23, 1995.
48. NOVITZKY D. aThe Impact of T3 on Survival in High Risk Cardiac Surgery Pati
entsa. Presentation at Emory University Division of Cardio-thoracic Anesthesiolo
gy Annual Postgraduate Course, Cardiopulmonary Bypass in the 90as VI, Atlanta, G
eorgia, September 6-8, 1996.
49. NOVITZKY D, SMITH D, FONTANET H. aT3, A New Therapeutic Modality in Open He
art Surgerya. Presented at the 45th International Congress of the European Socie
ty for Cardiovascular Surgery Symposium, Benice, Italy, September 15-18, 1996.
50. NOVITZKY D, PERRY RW, FONTANET HL, SMITH DB. aMitral Valve Replacement, A b
ench Approacha. Accepted for presentation at the VIIIth Annual Cardiac and Gene
ral Thoracic Surgery Update, Rio Mar, Puerto Rico, December 4-7, 1996.
51. NOVITZKY D. aThe Impact of T3 on Survival in High Risk Cardial Surgery Pati
entsa. Presented at the 19th Annual Meeting of the Society of Cardiovascular Ane
sthesiologists, Baltimore, Maryland, May 10-14, 1997.
52. NOVITZKY D. aAlternatives to Organ Transplantationa. Presented at the Annu
al Symposium of the International Society for Organ Sharing, Washington, D.C., J
uly 1997.
53. NOVITZKY D. aDonor Management: The State of the Arta. Presented at the In
ternational Society of Transplant Coordinators, Washington, D.C., July 1997.
54. NOVITZKY D. aDetrimental Effects of Brain Death in the Organ Donora. Prese
nted at the Annual Symposium of the International Society for Organ Sharing, Was
hington, D.C., July 1997.
55. NOVITZKY D. aAdvances in Cardiac Surgery. Minimally Invasive Coronary Surg
ery and Total Myocardial Revascularization Off Cardiopulmonary Bypass & The Mana
gement of End Stage Heart Failure: Partial Left Ventriculectomya. Presented a
symposium at the Tampa General Hospital in conjunction with the University of S
outh Florida College of Medicine, Tampa, Florida, February 6-7, 1998.
56. NOVITZKY D. aTotal Myocardial Revascularization Without Cardiopulmonary Byp
assa. Presented at the Florida Society of Thoracic and Cardiovascular Surgeons
31st Annual Meeting, Naples, Florida, February 20-22, 1998.

57. NOVITZKY D. aClinical Outcome After aOff-Pumpa Surgerya and aLeft Ventricul
ar Remodeling forthe Treatment of End Stage Heart Failurea. Presented at the Ca
rdiovascular Interventions a98 Third Annual Symposium at the Tampa Convention
Center, Tampa, Florida, February 26-28, 1998.
58. NOVITZKY D. aTotal Myocardial Revascularization Without Cardiopulmonary Byp
assa. Presented at CARDIOSTIM 98, 11th International Congress, Nice Acropolis, F
rench Riviera, FRANCE June 17-20, 1998.
59. NOVITZKY D. aTotal Myocardial Revascularization Without Cardiopulmonary Byp
assa. Poster presentation presented at the International Society for Minimally
Invasive Cardiac Surgery (ISMICS), Minneapolis, Minnesota June 25-27, 1998.
60. NOVITZKY D. aResults of Myocardial Revascularization Without Cardiopulmonar
y Bypassa. Invited Guest Speaker. Presented at the Advanced Laparoscopy Traini
ng Center (ALTC) during the Minimally Invasive Cardiac Surgery Course, Marietta,
Georgia July 17-18, 1998.
61. NOVITZKY D. aTotal Myocardial Revascularization Off Cardiopulmonary Bypass
& Minimally Invasive Coronary Surgerya. The 2nd Symposium presented at The Tamp
a General Hospital in conjunction with the University of South Florida College o
f Medicine and the James A. Haley Veterans Administration Hospital, Tampa, Flori
da, October 9, 1998
62. NOVITZKY D. aCoronary Surgery Without the Heart Lung Machinea. Presented a
t the International Society of Cardiothoracic Surgeons, 8th World Congress. Ho
uston, Texas, November 1-4, 1998.
63. NOVITZKY D. aBrain Monitoring During Hypotensive Anesthesia for Myocardial
Revascularization Without Cardiopulmonary Bypassa. Presented at the Magic of Mi
nimally Invasive Cardiac & Thoracic Surgery: A Comprehensive Training Program.
Jointly sponsored by The University of Cincinnati & The Endo-Surgery Institute,
Cincinnati, Ohio. November 13-14, 1998.
64. NOVITZKY D. aCoronary Surgery Off Cardiopulmonary Bypass: A Reviewa, Prese
nted at Yale University for Grand Rounds, New Haven, Connecticut. December 1-2,
1998.
65. NOVITZKY D. aNew Trends of Myocardial Revascularizationa. Guest Speaker at
the Scientific Forum VIII: On Cardiology and Cardiovascular Surgery in Belo Hor
izonte, Brazil. Performed Live Surgery at this symposium. December 11-13, 1998.

66. NOVITZKY D. aLive Surgery Telecast from the James A. Haley VA Hospital (Tam
pa, FL) to San Antonio, Texas. A Case of Myocardial Revascularization Off Car
diopulmonary Bypass - The USF Experiencea Presented at the 35th Annual Meeting o
f the Society of Thoracic Surgeons, San Antonio, Texas. January 22-27, 1999.
67. NOVITZKY D. aInternational Symposium of Total Myocardial Revascularizationa
. Presented at the Tampa General Hospital in conjunction with the University of
South Florida and the James A. Haley Veterans Administration Hospital, Tampa, Fl
orida. March 19-20, 1999.
68. NOVITZKY D. aChairman of Donor Management, Organ Preservation, Organ Distri
bution Sessiona. Conducted at the 19th Annual Meeting and Scientific Sessions In
ternational Society for Heart and Lung Transplantation. April 21-24, 1999.
69. NOVITZKY D. aInvited Guest Speaker at the University of Guayaquil in Ecuado
r, South America. Performing (2) Live Surgeries at this meeting. June 17-20, 19
99.
70. NOVITZKY D. aInvited Guest Speaker at the 1st Japanese Symposium on Myocard
ial Revascularization Off Cardiopulmonary Bypass, Tokyo, Japan. Performed Live
Surgery at this meeting. July 2-6, 1999.
71. NOVITZKY D. aInvited Guesta to return to the University of Guayaquil in Ec
uador, South America or the dedication of the hospital. July 28-31, 1999.
72. NOVITZKY D. Invited Guest Speaker for aBack to the Future: On Pump, Off Pu
mp Coronary Artery Surgery for the New Millenniuma at the Buffalo General Hospit
al, Buffalo, New York. August 12-15, 1999.
73. NOVITZKY D. Invited Guest Speaker for aEsperiencia de 20 Anox en Trasplante
s Cardiacos and Experiencia con Cirugia Coronaria Sin CEC at the VIII Meeting of
Cardiovascular Surgeons in Tucuman, Argentina, September 2-4, 1999.
74. NOVITZKY D. aInternational Symposium of Total Myocardial Revascularizationa
. Presented at The Tampa General Hospital in conjunction with the University of
South Florida and the James A. Haley Veterans Administration Hospital, Tampa, Fl
orida. March 17-18, 2000.
75. NOVITZKY D. aMinimally Invasive Cardiac Surgery (MICS) II: Outcomes, Innov
ations and Future Directionsa. Invited Guest Speaker on the topic of aCNS Monit
oring in High-Risk OPCAB Patientsa in Key West, Florida. May 28, 2000.
76. NOVITZKY D. a3rd Annual International Symposium of Total Myocardial Revascu
larizationa. Presented at The Tampa General Hospital in conjunction with the Uni
versity of South Florida and the James A. Haley Veterans Administration Hospital
, Tampa, Florida. March 16-17, 2001.
77. NOVITZKY D. aCoronary Artery Surgery on a Beating Heart Symposiuma. Presen
ted in Havana, Cuba. April 20-23, 2001.
78. NOVITZKY D. Invited guest speaker for aInterventional Cardiology & Cardiov
ascular Surgery Updatea in conjunction with the University of South Florida and
the University at Sea Program. May 13-20, 2001.
79 NOVITZKY D. Invited guest speaker at the aBaltic Sea Cardiothoracic Confere
ncea. Presented in Gdansk, Poland. May 29-June 4, 2001.
80 NOVITZKY D. a2nd International Workshop on Complete Myocardial Revasculariz
ation withoutCardiopulmonary Bypassa. Presented in Buenos Aires, Argentina. Au
gust 10, 2001.
81 NOVITZKY D. aCardiac Grand Roundsa. Invited guest speaker on aOff Pump By-Pa
ss Cardiac Surgery in 2001a. Presented at Tampa General Hospital, Tampa, Flori
da. September 5, 2001.
82. NOVITZKY D. Invited guest speaker at the a2nd International Taller of Heart
Failure and Intrathoracic Organs Transplantation Meetinga. Presented in Havana,
Cuba. November 5-8, 2001.
83. NOVITZKY D. a5th Annual International Symposium of Total Myocardial Revascu
larizationa. Presented at The Tampa General Hospital in conjunction with the Uni
versity of South Florida and the James A. Haley Veterans Administration Hospita
l, Tampa, Florida. March 15-16, 2002.
84. NOVITZKY D. Invited guest speaker at the a3rd International Taller of Heart
Failure and Intrathoracic Organs Transplantation Meetinga. Presented in Havana,
Cuba. March 25-29, 2002.
85. NOVITZKY D. Invited guest speaker at the aOff-Pump Coronary Surgery Symposi
uma. Presented in Hong Kong. April 8-9, 2002.
86. NOVITZKY D. Invited guest speaker at the a2nd Annual National VA Surgery Sy
mposiuma. Presented in Alexandria, Virginia. May 22-24, 2002.
87. NOVITZKY D. Presenter at the a5th Annual Meeting of the International Societ
y for Minimally Invasive Cardiac Surgerya. Presented in New York, New York. June
20-23, 2002.
88. NOVITZKY D. Invited guest speaker and moderator at the aInternational Societ
y for Heart and Lung Transplantation 4th Fall Educationa. Presented in Cambrid
ge, England. September 15-17, 2002.
89 NOVITZKY D. Course Director for the a6th Annual International Symposium of To
tal Myocardial Revascularization Without Cardiopulmonary Bypassa. Presented at T
he Tampa General Hospital in conjunction with the University of South Florida,
the James A. Haley Veterans Administration Hospital, Tampa, Florida, and the Uni
versity of Miami School of Medicine. August 29-30, 2003.
90. NOVITZKY D. Invited guest participant at the aAnnual Chilean Society of Card
iology & Cardiovascular Surgery Meetinga. Presented in Vina del Mar, Chile. Dece
mber 9-12, 2003.
91. NOVITZKY D. Invited guest speaker at the aCanadian Forum on Medical Manageme
nt to Maximize Donor Organ Potentiala. Presented in Mont Tremblant, Quebec. Feb
ruary 23-25, 2004.
92. NOVITZKY D. Invited guest faculty at the a10th Annual CTT Meeting 2004a. P
resented in Miami Beach, Florida. March 10-13, 2004.
93. NOVITZKY D. Invited guest participant at the aOutcomes Key West Meetinga. Pr
esenting in Key West, Florida. May 19-23, 2004.
94. NOVITZKY D. Invited guest speaker at the aBolivian Society of Thoracic & Car
diovascular Surgery Meetinga. Presented in Cochabamba, Bolivia. September 16-18,
2004.
95. NOVITZKY D. Speaker at the aDSMV Meeting: Veteranas Administration Review of
Cooperative Study #517a. Presented in Baltimore, Maryland. April 19, 2005.
96. NOVITZKY D. Reducing the Risk of Myocardial Revascularization: Relevance of
Multimodal Brain Monitoring Semin Cardiothorac Vasc Anesth.2005; 9: 131-137
97. NOVITZKY D. Invited guest speaker at the Thomas E. Starzl Transplantation In
stitute Grand Rounds a" aHeart Transplantation: Donor Organ Managementa. Presen
ted in Pittsburgh, Pennsylvania. September 23, 2005.
98. NOVITZKY D. aCardiology Crisp Grand Roundsa. Invited guest speaker on aHear
t Transplant Overviewa. Presented at Tampa General Hospital, Tampa, Florida. Fe
bruary 15, 2006.
99 NOVITZKY D. ISHLT chair at adonor research managementa Boston, Massachusetts.
May 2008
100. NOVITZKY D. Invited guest speaker at the aASTa annual meeting, Orlando Flo
rida, May 2008

BOOKS
1. Heart Transplantation - The Present Status of Orthotopic and Heterotopic
Heart Transplantation, edited by Cooper, DKC and Lanza, RP, MTP Press
Limited, Lancaster, 1984.
Personal Contributions:
Chapter 8, Pages 103-108. Surgical techniques of orthotopic and heterotopic
heart transplantation. NOVITZKY D, COOPER DKC.
Chapter 9, Pages 129-146. Immediate post-operative care and maintenance
immunosuppressive therapy. COOPER DKC, NOVITZKY D.
Chapter 12, Pages 177-194. Diagnosis and management of acute rejection.
COOPER, DKC, NOVITZKY D.

Chapter 21, Pages 321-340. Transplantation of the heart and both lungs.
NOVITZKY D, COOPER DKC.
2. Hormonal Therapy - A New Concept in the Management of Organ Donors,
edited by COOPER DKC, NOVITZKY D, ZUHDI N. (Proceedings of the Fourth
Annual Christiaan N. Barnard Symposium, December 4, 1987). Published as an
edition of Transplantation Proceedings, October 1988.

Personal Contributions:
1. COOPER DKC, NOVITZKY D, WICOMB WN. Pathophysiology of brain-
death in the experimental animal: Extracranial aspects: (i) Hemodynamic
and electrocardiographic responses.
2. ROSE AG, NOVITZKY D, COOPER DKC. Pathophysiology of brain-death
in the experimental animal: Extracranial aspects: (ii) Myocardial and
pulmonary histopathological changes.
3. NOVITZKY D, COOPER DKC, WICOMB WN. Pathophysiology of brain-
death in the experimental animal: Extracranial aspects: (iii) Endocrine
changes and metabolic responses.
4. WICOMB WN, COOPER DKC, NOVITZKY D. Added effects of organ (he
art) storage following brain-death in the experimental animal.
5. COOPER DKC, NOVITZKY D, WICOMB WN. Hormonal therapy in the
brain-dead experimental animal.
6. WICOMB WN, NOVITZKY D, COOPER DKC. Effects of hormonal therapy on subsequent
organ (kidney) storage in the experimental
animal.
7. NOVITZKY D, COOPER DKC. Results of hormonal therapy in human
brain-dead potential organ donors.
8. NOVITZKY D, COOPER DKC, ZUHDI N. T3 Therapy in the cardiac
transplant recipient.
9. Transplantation and Replacement of Thoracic Organs. COOPER DKC,
NOVITZKY D (Eds.). Kluwer Academic, Lancaster, UK 1990.
Personal Contributions in the Following Chapters:
SECTION I: Orthotopic and Heterotopic Heart Transplantation.
Chapter 6 - COOPER DKC, NOVITZKY D. Selection and management of
the donor.
Chapter 10 - COOPER DKC, NOVITZKY D. Surgical technique of orthotopic
heart transplantation.
Chapter 11 - NOVITZKY D, COOPER DKC. Surgical technique of heterotopic heart t
ransplantation.
Chapter 14 - NOVITZKY D, COOPER DKC. Immunobiology of allograft destruction.
Chapter 16 - COOPER DKC, NOVITZKY D. Diagnosis and management of acute
rejection.
Chapter 20 - COOPER DKC, NOVITZKY D. Retransplantation.

SECTION II: Transplantation of the Heart and Both Lungs.

Chapter 35 - HAVERICH A, NOVITZKY D, COOPER DKC. Selection of donor;
excision and storage of the donor organs.

Chapter 37 - NOVITZKY D, COOPER DKC. Surgical technique of recipient

operation.
4. Organ Donation, Procurement and Preservation of Vascularized Organs,
Kluwer Academic Publishers, The Netherlands, 1994.
Personal Contributions:
Chapter 5 - NOVITZKY D. Special Problems in Donor Maintenance, issues of T
riiodothyronine in cardiac recovery (In press).
5. Procurement, Preservation and Allocation of Vascularized Organs,
Kluwer Academic Publishers, The Netherlands, 1997
Personal Contributions:
Chapter 8 - NOVITZKY D. Donor conditioning in organ procurement, pp. 59-68
, 1997.
6. Organ Procurement & Preservation,
Klintmalm & Levy, Landes Bioscience Vademecum Publishers, U.S.A. 1998
Personal Contributions:
Chapter 3 - NOVITZKY D. Physiologic Consequences of Brain Death, pp. 3168,
1997.
7. THE BRAIN-DEAD ORGAN DONOR
Pathophysiology and Management
DIMITRI NOVITZKY, MD, PHD, FCS
Book in preparation. 2010
CONTRIBUTIONS TO BOOKS - INVITED ARTICLES

1. COOPER DKC, NOVITZKY D, HASSOULAS J, BARNARD CN. Transplantation of the heart

. Brit J Clinic Practice, Vol. 36, pp. 337-345, 1982. Reprinted in the Indian J
ournal of Thoracic and Cardiovascular Surgery.
2. COOPER DKC, NOVITZKY D, HASSOULAS J, BARNARD CN. Heart transplantation: The
South African experience. J Heart Transplant, Vol. 2, 78-84, 1983.
3. NOVITZKY D, SANCHEZ H, BARNARD CN. The significance of femoral pulses in coa
rctation of the aorta. S Afr Med J, Vol. 65, 755-757, 1983.
4. NOVITZKY D, SANCHEZ H, BARNARD CN. Coarctation of the aorta under one year
of age. S Afr Med J, Vol. 64, 923, 1983.
5. COOPER DKC, NOVITZKY D, REICHART B. The current status of heart and heart-lu
ng transplantation. International Medicine, 5, 2-7, 1985.
6. NOVITZKY D, COOPER DKC, BARNARD CN. The surgical technique of heterotopic he
art transplantation. Chapter in Cardiac Surgery - a loose-leaf workbook, an upd
ate service, edited by D. Doty. Yearbook medical publisher, Chicago, 1986.
7. NOVITZKY D, COOPER DKC, BRINK J, REICHART B. Sequential second and third
African Cardiac Society, Sun City, 1986. J Clin Transplant 5, 57
- 62, 1987.
8. NOVITZKY D, COOPER DKC, BONIASZCZUK J, ROSE AG, SMITH JA, REICHART B. The eff
ect of denervation and acute rejection on left ventricular volumes measured by
radionuclide scanning techniques following cardiac transplantation in the Chacma
baboon. Sem Nuc Med 28:213-220, 1988.
9. ITURRALDE M, NOVITZKY D, COOPER DKC, ROSE AG, BONIASZCZUK J, SMITH JA, REICHA
RT B, ISAACS S. The role of nuclear cardiology procedures in the evaluation of
cardiac function following heart transplantation. Sem Nuc Med 18, 221-240, 198
8.
10. COOPER DKC, NOVITZKY D, WICOMB WN. Improved organ survival from brain-dead
donors. J Acc Emerg Med 5, 17-18, 1988.
11. REICHENSPURNER H, COOPER DKC, ODELL JA, NOVITZKY D, HUMAN PA, VON OPPELL U,
BECERRA E, BOEHM DH, ROSE AG, REICHART B. Heart transplantation in Cape Town -
a review of 20 years experience. In Assisted Circulation 3, edited by F. Unger.
Springer Verlag, Berlin, 1989, pp 425-436.
12. NOVITZKY D, COOPER DKC, BONIASZCZUK J, ISAACS S, ROSE AG, SMITH JI. Acute c
ardiac rejection by left ventricle volume measurement using radionuclide techniq
ues. J Nuc Med.
13. NOVITZKY D. Selection and management of cardiac allograft donors. Current
Opinion inCardiology 1996, 11:174-182.

PAPERS ON CLINICAL CARDIOVASCULAR SURGICAL TOPICS

1. BARNARD CN, BARNARD MS, COOPER DKC, CURCIO CA, HASSOULAS J, NOVITZKY D, WOLPO
WITZ A. The present status of heterotopic cardiac transplantation. J Thorac C
ardiovasc Surg 81:433 -439, 1981.
2. COOPER DKC, HASSOULAS J, NOVITZKY D, BARNARD CN. The results of orthotopic a
nd heterotopic heart transplantation at Groote Schuur Hospital, 1967-1982. J H
eart Transplant 1:112-115, 1982.
3. COOPER DKC, FRASER RC, ROSE AG, AYZENBERG O, OILFIELD GS, HASSOULAS J, NOVIT
ZKY D, UYS CH, BARNARD CN. Technique, complications and clinical value of endo
myocardial biopsy in patients with heterotopic heart transplants. Thorax 36:72
7-731, 1982.
4. LOSMAN JG, LEVINE H, CAMPBELL CD, REPLOGLE RL, HASSOULAS J, NOVITZKY D, COOPE
R DKC, BARNARD CN. Changes in indications for heart transplantation: An additi
onal argument for the preservation of the recipient's own heart. J Thorac Cardi
ovasc Surg 84: 716-726, 1982.
5. COOPER DKC, NOVITZKY D, HASSOULAS J, BARNARD CN. Transplantation of the Hear
t. The British Journal of Clinical Practice 36:337-245, 1982.
6. LANZA RP, COOPER DKC, NOVITZKY D, BARNARD CN. Survival after cardiac transpla
ntation (letter to the editor). S Afr Med J 64:1007, 1983.
7. ROSE AG, UYS CJ, NOVITZKY D, COOPER DKC, BARNARD CN. Toxoplasmosis of donor
and recipient hearts after heterotopic cardiac transplantation. Arch Pathol Lab
Med 107: 368-373, 1983.
8. NOVITZKY D, COOPER DKC, BARNARD CN. The surgical technique of heterotopic he
art transplantation. Ann Thorac Surg 36:476-482, 1983.
9. COOPER DKC, WICOMB WN, BOYD ST, LANZA RP, NOVITZKY D, HASSOULAS J,
BARNARD CN. Orthotopic and heterotopic heart transplantation: Aspects of the C
ape Town experience. Presented to the Transplantation Society, Brighton, 1982.
Transplant Proc 15:1232-1237, 1983.
10. COOPER DKC, LANZA RP, OLIVER S, FORDER AA, ROSE AG, UYS CJ, NOVITZKY D, BARN
ARD CN. Infectious complications after heart transplantation. Thorax, 38:822-
828, 1983.
11. NOVITZKY D, SANCHEZ HE, BARNARD CN. Coarctation of the aorta in infants und
er 1 year of age. South African Medical Journal 64:934-936, 1983.
12. SUKKAR AZ, COOPER DKC, DE NOBREGA J, HASSOULAS J, NOVITZKY D, SANCHEZ HE, BA
RNARD CN. Valve replacement in patients over 70 years of age. S Afr Med J 65
:370-373, 1984.
13. NOVITZKY D, COOPER DKC, BARNARD CN. Circulatory assistance with allograft (
letter to the editor). Ann Thorac Surg 37:2, 1984.
14. WICOMB WN, COOPER DKC, NOVITZKY D, BARNARD CN. Cardiac transplantation foll
owing storage of the donor heart by a portable hypothermic perfusion system. An
n Thorac Surg 37: 232-248, 1984.
15. NOVITZKY D, COOPER DKC, BARNARD CN. Orthotopic heart transplantation in a
patient with a heterotopic heart transplant. J Heart Transplant 3:257-259, 19
84.
16. VAN VELDHUISEN DB, VAN DEN BERG MP, NOVITZKY D, COOPER DKC. Cyclosporine A
in the management of patients with heart transplants. S Afr Med J 66:557-562,
1984.
17. NOVITZKY D, COOPER DKC, BARNARD CN. Reversal of acute rejection by cyclospo
rine in a heterotopic heart transplant. J Heart Transplant 3:117-120, 1984.
18. NOVITZKY D, BONIASZCUZUK J, COOPER DKC, ISAACS S, ROSE AG, SMITH JA, UYS CG,
BARNARD CN, FRASER RC. Prediction of acute cardiac rejection using radionuclid
e techniques. S Afr Med J 65:5-7, 1984
19. NOVITZKY D, COOPER DKC, ROSE AG, BARNARD CN. The value of recipient heart
assistance during severe acute rejection following heterotopic cardiac transpla
ntation. J Cardiovasc Surg 25:287-295, 1984.
20. NOVITZKY D, COOPER DKC, BARNARD CN. Heart transplantation at Groote Schuur
Hospital using cyclosporine. Poster presented to the International Society for
Heart transplantation, New York, 1984. J Heart Transplant 4:17-18, 1984.
21. NOVITZKY D, ROSE AG, MORGAN JA, BARNARD CN. Primary cardiac haemangiomas.
A report of 2 cases. S Afr Med J 66:267-270, 1984.
22. NOVITZKY D, SANCHEZ HE, HUMAN D, BARNARD CN. The significance of femoral pu
lses in coarctation of the aorta. S Afr Med J 65:755-757, 1984.
23. COOPER DKC, NOVITZKY D, LANZA RP, ROSE AG, WICOMB WN, BARNARD CN.
Immunosuppression in the baboon cardiac allograft model: Effects of splenectomy
, bolus methylprednisolone, propranolol, high-dose azathioprine, cyclophosphamid
e, and a nitridazole metabolite. Transplantation 38:299-301, 1984.

24. NOVITZKY D, WICOMB WN, COOPER DKC, ROSE AG, FRASER RC, BARNARD CN.
Electrocardiographic, hemodynamic and endocrine changes occurring during experim
ental brain death in the Chacma baboon. Presented to the International Society
for Heart Transplantation, New York, 1984 (President's Award). J Heart Transp
lant 4:63-69, 1984.
25. NOVITZKY D, COOPER DKC, LANZA RP, BARNARD CN. Further cardiac transplant
proceedings in patients with heterotopic heart transplants. Ann of Thoracic Sur
g 39:149-154, 1985.
26. COOPER DKC, NOVITZKY D, REICHART B. The current status of heart and heart-l
ung transplantation. International Medicine 5:2-7, 1985.
27. NOVITZKY D, COOPER DKC, DU TOIT E, OUDSHOORN M, LANGMAN E, JACOBS P. Prefor
med lymphocytotoxic antibodies disappear following cyclosporine therapy. J Hear
t Transplant 4:362-363, 1985.

28. NOVITZKY D, COOPER DKC, WICOMB CN, ROSE AG, REICHART B. Transplantation of
the heart and both lungs: experimental and clinical experience and review of th
e literature. S Afr Med J 67:575 - 580, 1985.
29. COOPER DKC, CHARLES RG, ROSE AG, FRASER RC, ISAACS S, NOVITZKY D, BARNARD C
N. Does the electrocardiogram detect early heart rejection? J Heart Transplant
4:546 - 549, 1985.
30. NOVITZKY D, COOPER DKC, BONIASZCZUK J, ISAACS S, FRASER RC, COMMERFORD PJ, U
YS CH, ROSE AG, SMITH JA, BARNARD CN. The significance of left ventricular volu
me measurement after heart transplantation using radionuclide techniques. J Hea
rt Transplant 4:206 - 209, 1985.

31. NOVITZKY D, COOPER DKC, BONIASZCZUK J, FRASER RC, ISAACS S, ROSE AG, SMITH J
, UYS CJ, BARNARD CN. Prediction of acute cardiac rejection using radionuclide
scanning to detect left ventricular volume changes. Transplant Proc 17: 218-2
20, 1985.
32. WICOMB WN, COOPER DKC, NOVITZKY D. An airlife pump device for low pressure
perfusion storage of the isolated heart. Cryobiology 22:401-408, 1985.
33. NOVITZKY D, COOPER DKC, WICOMB WN. A successful method of administering cyc
losporin A to the Chacma baboon. S Afr Med J 68:737-739 , 1985.
34. COOPER DKC, WICOMB WN, LANZA RP, NOVITZKY D, ROSE AG, BARNARD CN. Effects o
f brain death and hypothermic perfusion storage on donor heart function: An exp
erimental study. Presented to the Transplantation Society, Minneapolis, 1984.
Transplant Proc 17:231-232, 1985.
35. COOPER DKC, BECERRA E, NOVITZKY D, HORAK A, REICHART B. Surgery in patients
with heart transplants: Anesthetic and operative considerations. S Afr Med J
70:137-142, 1986.
36. WICOMB WN, NOVITZKY D, COOPER DKC, ROSE AG. Forty-eight hours hypothermic
perfusion storage of pig and baboon hearts. Presented to the South African Tran
splantation Society, Ceres, 1985. (Abstract in S Afr J Surg 24, 15, 1986). J
Surg Research 40:276-284, 1986.
37. COOPER DKC, NOVITZKY D, BECERRA E, REICHART B. Are there indications for
heterotopic heart transplantation in 1986? A 2 to 11 year follow-up to 49 conse
cutive patients undergoing heterotopic heart transplantation. Presented to the
South African Cardiac Society, Sun City, 1986. The Thoracic and Cardiovasc Surg
eon 34:300-304, 1986.
38. BHOOPCHAND A, COOPER DKC, NOVITZKY D, ROSE AG, REICHART B. Regression of Ka
posi's sarcoma after reduction of immunosuppressive therapy in a heart transplan
t patient. J Heart Transplant 5:461-464, 1986.
39. NOVITZKY D, COOPER DKC, REICHART B. Value of triiodothyronine (T3) therapy
to brain-dead potential organ donors. (Letter) J Heart Transplant 5:486-7, 1
986.
40. WICOMB WN, COOPER DKC, NOVITZKY D. Impairment of renal slice function follo
wing brain death, with reversibility of injury by hormonal therapy. Transplanta
tion 41:29-33, 1986.
41. NOVITZKY D, ROSE AG, COOPER DKC, REICHART B. Interpretation of endomyocardi
al biopsy after heart transplantation. S Afr Med J 70:789-792, 1986.
42. WICOMB WN, COOPER DKC, LANZA RP, NOVITZKY D, ISAACS S. The effects of brain
death and 24 hour storage by hypothermic perfusion in donor heart function in t
he pig. J Thorac Cardiovasc Surg 91:896-909, 1986.
43. NOVITZKY D, WICOMB WN, COOPER DKC, ROSE AG, REICHART B. Prevention of
myocardial injury during brain death by total cardiac sympathectomy in the Chacm
a baboon. Ann Thorac Surg 41:520-4, 1986.
44. COOPER DKC, NOVITZKY D, ROSE AG, REICHART B. Acute pulmonary rejection prec
edes cardiac rejection following heart-lung transplantation in a primate model.
Paper presented to the International Society for Heart transplantation, New Yor
k, 1986.
45. NOVITZKY D, COOPER DKC, ROSE AG, REICHART B. Acute isolated pulmonary rejec
tion following transplantation of the heart and both lungs: Experimental and cl
inical observations. Ann Thorac Surg 42:180-4, 1986.

46. NOVITZKY D, COOPER DKC, WICOMB WN, REICHART B. Hemodynamic changes,

myocardial injury, and pulmonary edema induced by sympathetic activity during th
e development of brain death in the baboon. Presented to a Symposium on Organ P
rocurement, Detroit, 1985. Transplant Proc 18:609-12, 1986.

47. NOVITZKY D, COOPER DKC, WICOMB WN, REICHART B. Brain death-induced

hemodynamic changes resulting in cardiac pulmonary injury in the baboon. Paper
presented to the European Society for Organ Transplantation, Munich, 1985. Tran
splant Proc 18:1190-192, 1986.
48. ROSE AG, NOVITZKY D, COOPER DKC, REICHART B. Endomyocardial biopsy site
morphology: An experimental study in baboons. Arch Pathol Lab Med 110:622-625
, 1986.
49. WICOMB WN, ROSE AG, COOPER DKC, NOVITZKY D. Hemodynamic and myocardial hist
ological and ultrastructural studies on baboons from three to twenty-seven month
s following autotransplantation of hearts stored by hypothermic perfusion for 24
or 48 hours. J Heart Transplant 5:122-9, 1986.

50. NOVITZKY D, WICOMB WN, COOPER DKC, REICHART B. Evidence of myocardial and r
enal unctional recovery following hormonal treatment after brain death. Present
ed to the South African Transplantation Society, Ceres, 1985 (Abstract in S Afr
J Surg 24, 50, 1986), and to a Symposium on Organ Procurement, Detroit, 1985.
Transplant Proc 18:613-5, 1986.
51. NOVITZKY D, ROSE AG, COOPER DKC, REICHART B. Interpretation of endomyocardi
al biopsy after heart transplantation. Potentially confusing factors. S Afr Me
d J 70:789-92, 1986.
52. NOVITZKY D, COOPER DKC, WICOMB WN, REICHART B. Improved function of stored
hearts following hormonal therapy after brain death in pigs. Presented to the E
uropean Society for Organ Transplantation, Munich, 1985. Transplant Proc 18:1
419-21, 1986.
53. NOVITZKY D, ROSE AG, COOPER DKC, REICHART B. Histopathological changes at t
he site of endomyocardial biopsy: Potential for confusion with acute rejection.
Poster presented to the International Society for Heart Transplantation, New Y
ork, 1986. J Heart Transplant 5:79-80, 1986.
54. REICHART B, COOPER DKC, NOVITZKY D. The artificial heart - a reality in 198
6. Medical Researched Council (SA) News 17:8-9, 1986.
55. COOPER DKC, NOVITZKY D, REICHART B. Current cardiothoracic research project
s. Medical Research Council (SA) News 17:5-7, 1986.
56. REICHENSPURNER H, ODELL JA, COOPER DKC, NOVITZKY D, HUMAN PA, VON OPPELL U,
BECERRA E, BOEHM DH, ROSE AG, FASOL R, ZILLA P, REICHART B. Twenty years of h
eart transplantation at Groote Schuur Hospital. J Heart Transplant 6:317-323,
1987.
57. NOVITZKY D, COOPER DKC, BRINK JG, REICHART B. Sequential - second and thir
transplants in patients with heterotopic heart allografts. Clin Transplant 1:
57-62, 1987.
58. NOVITZKY D, COOPER DKC, ROSE AG, WICOMB WN, BECERRA E, REICHART B. Early do
nor heart failure following transplantation from myocardial injury sustained dur
ing brain death. Clin Transplant 1:108-13, 1987.
59. REICHART B, BLASCHKE F, COOPER DKC, NOVITZKY D, REICHENSPURNER H, ODELL JA,
ROSE AG, KEMKES BM, KLINNER W. Transplantation of the heart and both lungs: In
itial experience of twelve operations in ten patients. Clin Transplant 1:231-
239, 1987.
60. NOVITZKY D, COOPER DKC, REICHART B. Hemodynamic and metabolic responses to
hormonal therapy in brain-dead potential organ donors. Transplantation 43:85
2- 854, 1987.
61. NOVITZKY D, COOPER DKC, REICHART B. The value of hormonal therapy in improv
ing organ viability in the transplant donor. Presented to the Transplantation S
ociety, Helsinki, and to the Society of Thoracic and Cardiovascular Surgeons of
Great Britain and Ireland, Edinburgh, Transplant Proc 19:2037-2038, 1987.
62. BECERRA E, COOPER DKC, NOVITZKY D, REICHART B. Are there indications for
heterotopic heart transplantation today? Presented to the Transplantation Socie
ty, Helsinki, and to the Society of Thoracic and Cardiovascular Surgeons of Grea
t Britain and Ireland, Edinburgh, 1986. Transplant Proc 19:2512-2513, 1987
.
63. REICHART B, REICHENSPURNER H, ODELL JA, COOPER DKC, NOVITZKY D, HUMAN PA, VO
N ODELL U, BECERRA E, BOEHM DH, ROSE AG. Heart transplantation at Groote Schuur
Hospital, Cape Town - Twenty years experience. S Afr Med J 72:737-739, 1987.

64. NOVITZKY D, COOPER DKC, MORRELL D, ISAACS S. Brain death, triiodothyronine

(T3) depletion, and inhibition of oxidative phosphorylation: Relevance to manag
ement of organ donors. Transplant Proc 19:4110-1, 1987.
65. WICOMB WN, COOPER DKC, NOVITZKY D. Loss of myocardial viability following
hypothermic perfusion storage from contaminating trace elements in th
e perfusate.
Transplantation 45:23-9, 1987.

66. NOVITZKY D, WICOMB WN, COOPER DKC, TJAALGARD MA. Improved cardiac function
following hormonal therapy in brain-dead pigs: Relevance to organ donation. Cr
yobiology
24:1-10, 1987.
67. NOVITZKY D, WICOMB WN, ROSE AG, COOPER DKC, REICHART B. Pathophysiology of
pulmonary edema following experimental brain death in the Chacma baboon. Ann Th
orac Surg 43:288-94, 1987.
68. NOVITZKY D, COOPER DKC, ROSE AG, REICHART B. Prevention of myocardial injur
y by pre-treatment with verapamil hydrochloride prior to experimental brain deat
h: Efficacy in a baboon model. Amer J Emerg Med 15:11-18, 1987.
69. NOVITZKY D, COOPER DKC, MORRELL D, ISAACS S. Brain death, triiodothyronine
(T3) depletion, and inhibition of oxidative phosphorylation - relevance to manag
ement of organ donors. Presented to the European Society for Organ Transplantat
ion, Gothenburg, 1987. Transplant Proc 19:4068-4069, 1987.
70. NOVITZKY D, COOPER DKC, REICHART B. Preservation of organs & acute tubular
necrosis: Procurement and preservations of organs: The value of hormonal therap
y in improving organ viability in the transplant donor. Transplant Proc 19:203
7-2038, 1987.

71. REICHART BA, HUMAN PA, ROSE AG, NOVITZKY D, COOPER DKC. Is pulmonary ischem
ia a factor in the reperfusion response? An experimental study in the Chacma ba
boon. Presented to the International Society for Heart Transplantation, New Orl
eans, 1987. Berg-en-Dal, 1987. J Heart Transplant 6:238-243, 1987.
72. REICHART BA, NOVITZKY D, COOPER DKC, CUNNINGHAM MS, ROSE AG. Successful orth
otopic heart-lung transplantation in the baboon after 5 hours cold ischemia with
cardioplegia and Collins' solution. Presented to the International Society for
Heart Transplantation, New York, 1986, and South African Transplantation Societ
y, Berg-en-Dal, 1987. J Heart Transplant 6:15-22, 1987.
73. REICHENSPURNER H, ODELL JA, COOPER DKC, NOVITZKY D, ROSE AG, KLINNER W, REI
CHART B. Initial experience with heart and lung transplantation. Presented to
the 17th Annual Symposium of the Texas Heart Institute, Houston, 1987. Texas He
art Institute Journal 15:3-6, 1988.
74. COOPER DKC, SUMPTER P, NOVITZKY D, CHAFFIN J, GREER AE, BARNARD CN, Z
UHDI Assessment and selection of patients for heart transplantation. J Okla Sta
te Med Assoc 81:137-140, 1988.
75. COOPER DKC, ROMERO CA, CLARK RM, CHAFFIN JA, GREER AE, NOVITZKY D, BARNARD C
N, ZUHDI N. Indications for heterotopic heart transplantation, and report on tw
o patients. J Okla State Med Assoc 81:513-517, 1988.
76. NOVITZKY D, COOPER DKC, ZUHDI N. Triiodothyronine therapy in the cardiac tr
ansplant recipients. Presented as a poster at an International Organ Transplant
Forum in honor of Dr. T.E. Starzl, Pittsburgh, 1987, Transplant Proc 20:65-8,
1988.
77. COOPER DK, NOVITZKY D, WICOMB WN. Hemodynamic and electrocardiograhic respo
nses. Trans Proc 20:25-8, 1988.
78. ROSE AG, NOVITZKY D, COOPER DK. Myocardial and pulmonary histopathologic
changes. Trans Proc 20:29-32, 1988.
79. NOVITZKY D, COOPER DK, WICOMB WN. Endocrine changes and metabolic response
s. Trans Proc 20:33-8, 1988.
80 WICOMB WN, COOPER DK, NOVITZKY D. Added effects of organ (heart) storage aft
er brain death in the experimental animal. Trans Proc 20:39-43, 1988.
81 COOPER DK, NOVITZKY D, WICOMB WN. Hormonal therapy in the brain-dead experim
ental animal. Trans Proc 20:51-4, 1988.
82 WICOMB WN, NOVITZKY D, COOPER DK, Effects of hormonal therapy on subsequent o
rgan (kidney) storage in the experimental animal. Trans Proc 20:55-8, 1988.
83 NOVITZKY D, COOPER DK. Results of hormonal therapy in human brain-dead poten
tial organ donors. Trans Proc 20:59-62, 1988.
80. NOVITZKY D, COOPER DKC, BONIASZCZUK J. Prediction of acute cardiac rejectio
n by changes in left ventricular volumes. J Heart Transplant 7:453-455, 1988.
81. COOPER DKC, NOVITZKY D. Thyroid function in human cardiac allograft donors
(Letter).Transplantation 45:671-672, 1988.
86. NOVITZKY D, COOPER DKC, HUMAN PA, REICHART B, ZUHDI N. Triiodothyronine the
rapy for heart donor and recipient. J Heart Transplant 7:370-376, 1988.
87. ROSE AG, NOVITZKY D, PRICE SK. Heterotopic thyroid tissue in the heart.
Am J of Cardiovasc Pathol 1:401-404, 1988.
88 Hermann Reichenspurner, MD, John A. Odell, MB, ChB, David K.C. Cooper, MD, D
IMITRI NOVITZKY, MD, Alan G. Rose, MB, ChB, Werner Klinner, MD, and Bruno Reicha
rt, MD. Initial Experience with Heart and Lung Transplantation. Tex Heart Inst J
. 1988; 15(1): 3a"6
89 NOVITZKY D, HUMAN PA, COOPER DKC. Effect of triiodothyronine (T3) on myocard
ial high-energy phosphates and lactates following ischemia and cardiopulmonary b
ypass - An experimental study in baboons. J Thorac Cardiovasc Surg 96:600-607,
1988.
90 NOVITZKY D, COOPER DKC. The physiological management of cardiac transplant d
onors and recipients using triiodothyronine (T3). Presented as a poster at the
International Organ Transplant Forum in honor of Dr. T.E. Starzl, Pittsburgh, 1
987. Transplant Proc 20: