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NIPER DEMO PAPER 1

Q1. Diel’s – Alder reaction is an example of

A. Cycloaddition reaction
B. Pericyclic reaction
C. Sigmatropic reaction
D. none of the above
Q2. In Oxo process the catalyst used is
A. CO2 [Co8]
B. CO2 [Co6]
C. CO2 [Co 4]
D. none of the above
Q3. Generally the particle size in suspension is (micrometer)
A. 10 – 1000
B. 100 – 1000
C. 10 – 100
D. can be of any size
Q4. Flow Point can be defined as in case of
A. Emulsion
B. Colloidal
C. Suspension
D. none
Q5. Indian Pharmacopoeia is published by
A. Ministry of Health and Family Welfare
B. Deptt. Of Pharmaceuticals
C. D.C.G.I
D. Ministry of Chemicals
Q6. First Edition of Indian Pharmacopoeia was published in
A. 1955
B. 1966
C. 1985
D. 1976
Q7. Total number of enzyme involved in degradation of fatty acids are
A. 5
B. 7
C. 9
D. 4

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Q8. Sulfonamides act by competing with PABA for the enzyme
A. Dihydroptreoate synthtase
B. H. Pylori
C. CAT
D. none
Q9. Near IR range is at ( in micron)
A. 0.8 – 2
B. 2 – 15
C. 15 – 1000
D. none
Q10. In IR spectra the stretching is due to
A. change in symmetry of the compound
B. change in bond angle of the compound
C. change in bond strength of the compound
D. change in bond lenght of the compound
Q11. Various types of instruments used in IR except
A. Nerst glower
B. Globar source
C. Incandescent wire
D. Tungsten lamp
Q12. Sulfonamides are given in combination with which one of the following drug in
treatment of malaria
A. Trimethoprim
B. Itraconazole
C. Pyrimethamine
D. none
Q13. Mechanism of drug resistance in sulfonamides is due t
A. Alteration in the binding sites
B. Blockage of the pathways
C. Reduction of drug uptake
D. Plasmid mediated
Q14. Co – Trimoxazole is combination of
A. Sulfasalazine and sulfadiazine
B. Sulfadiazine and methotrexate
C. Sulfadiazine and Sulfamethoxazole
D. Sulfamethoxazole and trimethoprim
Q15. Bolometer is used in
A. UV
B. NMR
C. MS
D. IR

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Q16. Central Drug Laboratory (biological and microbiological samples are tested) is
located at?
A. Kolkota
B. Lucknow
C. Kasauli
D. Delhi
Q17. Central Research Institute (CRI) is located at? (sera, vaccine, antigen, antitoxin tests
and Rabbies research)
A. Kolkota
B. Lucknow
C. Kasauli
D. Delhi
Q18. Indian Veterinary Research Institute is located at?
A. Pune
B. Izatnagar
C. Kanpur
D. Ghaziabad
Q19. What is the antonym of Allay?
A. Pacify
B. Stimulate
C. Moderate
D. Peter Out
Q20. Phantom and Specter are ___________ ?
A. Synonyms
B. Antonyms
C. Idioms
D. None of the above
Q21. Water act as
A. Nucleophile
B. Electrophile
C. Both
D. None
Q22. Pure water is
A. 58.0 M
B. 55.0 M
C. 55.56 M
D. none
Q23. Dissociation const. of water is
A. 2 x 10-16 mol/L
B. 3 x 10-16 mol/L
C. 1.8 x 10-16 mol/L
D. none

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Q24. Water is
A. Monopole
B. Dipole
C. Both
D. None
Q25. Favorskii rearrangement is a conversion of
A. β- hydroxyl ester to α- halo ester
B. α- halo ester to β- hydroxyl ester
C. α- halo ester to ester
D. none
Q26. Curtius reaction is a conversion of
A. Acylazide to isocynate
B. Isocynate to acylazide
C. Nitrile to acid
D. None
Q27. β- Lactamase inhibitor is
A. Oxacillin
B. Carbenicillin
C. Ticarcillin
D. Sulbactam
Q28. First line drug for meningitis is
A. Carbenicillin
B. Sulbactam
C. Amoxicillin
D. Ampicillin
Q29. How many steps are common in gluconeogenesis and glycolysis
A. 6
B. 5
C. 7
D. 8
Q30. In glycogenesis formation of branching is done by the enzyme
A. Fructose – 6 phosphtase
B. Glucose – 6 phosphtase
C. Glucosyl α – 4- 6 transferase
D. None
Q31. A sum of money amounts to Rs.8968/- in 3 years and Rs.9424/- in 4 years at 6%
simple interest. What is the sum?
A. Rs.7600
B. Rs.7700
C. Rs.7800
D. Rs.8000

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Q32. In 2009, Nobel Peace Prize
A. Barack Obama
B. Venkatraman Ramakrishnan, Thomas Steitz and Ada Yonath
C. Herta Mueller
D. Elinor Ostrom and Oliver Williamson
Q33. In 2009, The Nobel Memorial Prize in Economic Sciences
A. Elinor Ostrom and Oliver Williamson
B. Elizabeth H. Blackburn, Carol W. Greider and Jack W. Szostak
C. Herta Mueller
D. Charles K. Kao, Willard S. Boyle and George E. Smith. Kao
Q34. Central Drug Testing Laboratory (CDTL) is located at?
A. Kanpur
B. Chennai
C. Delhi
D. Bombay
Q35. Indian Drug Manufacturing Association (IDMA) is located at?
A. Kanpur
B. Chennai
C. Delhi
D. Bombay
Q36. Nujol mull is
A. Lipidic
B. Fat
C. Mineral
D. All
Q37. Sample preparation in IR can be done by
A. Salt plates
B. KBr plates
C. Nujol mull
D. All
Q38. Increase in S – character IR causes absorption to move
A. Left side
B. Right side
C. Const.
D. None
Q39. As the atom bonded to C- atom increase in mass, the reduced mass also increases
then frequency
A. Also increases
B. Decreases
C. Const.

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 D. Depends on the situation
Q40. Simple aliphatic ether can be distinguished from alkane is by
A. C – C bond
B. C – H bond
C. Both a and b
D. C – O bond
Q41. Which one of the following is competitive displacement interaction
A. Warfarin by salicylates
B. Methotrexate by sulphonamides
C. Both the above
D. None
Q42. The cyclic ester in IR appears at ( in cm-1)
A. 1735 – 1770
B. 1690 – 1705
C. 1705 – 1770
D. None
Q43. Tetracycline acts by
A. Inhibiting protein systhesis
B. DNA disruption
C. Inhibiting RNA synthesis

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