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ARTICOLE DE SINTEZÃ

ADHD – FROM CHILD TO ADULT


Florina Rad*, Cristina Constantinescu**, Liviu Nicolae***, Iuliana Dobrescu****

Rezumat What today we call Attention Deficit


Din punct de vedere istoric ADHD (Attention- Hyperactivity Disorder (ADHD) is a disorder identified
deficit/hyperactivity disorder) a fost consideratã a fi many years ago that in time had numerous other terms
mai mult o afecþiune a copilãriei. Biederman, într-un and definitions. “ADHD” term translation in Romanian
studiu recent aratã cã simptomele persistã la vârsta language has different aspects like: Hyperactivity
adultã la 65% din copiii diagnosticaþi cu ADHD. Din Disorder/ Attention Deficit, Attention Deficit with
moment ce ADHD este o afecþiune care devine tot mai Hyperactivity, Hyperactive Disorder with or without
bine cunoscutã, adulþii care prezintã atât simptome Inattention. Considering there are many variants of
obiective cât ºi subiective de dificultate în concentrare translations in Romanian language the Chairmen of
ºi inatenþie devin candidaþi în vederea evaluãrii psihi- Psychiatry Departments in the University Centers
atrice pentru stabilirea unui diagnostic. agreed to keep the well known abbreviation – ADHD.
Simptomele de ADHD se modificã de la copil la The evolution of ADHD concept: we can find data
adolescent si apoi la vârsta adultã. Tipic, simptomele about children with ADHD in documents from as far as
de hiperactivitate descresc cu vârsta ºi se atenueazã, în year 1800. These symptoms have been considered to be
timp ce problemele legate de concentrare ºi organizare caused by lesions or central nervous system disorders.
devin dominante. Diagnosticul la adult devine ºi mai Stories of kids like “The Story of Fidgety Phillip” are
complicat prin suprapunerea simptomelor de ADHD cu suggestive for ADHD and it is possible that Phillip was
simptomele altor afecþiuni psihiatrice frecvent întâlnite suffering from it (1).
cum ar fi depresia ºi abuzul de droguri. We will present a historical retrospective of the
Certitudinea diagnosticului de ADHD la vârsta term “ADHD” that shows that ADHD is a real disorder
adultã este o provocare ºi necesitã atenþie la simp- and not just a “postmodern disease” (2):
tomele de debut, de inatenþie, distractibilitate, impul- ADHD is one of the most frequent disorders of the
sivitate ºi labilitate emoþionalã. childhood being associated with long term psycho-
Cuvinte cheie: ADHD, copil, adult, calitatea vieþii. social consequences. ADHD is a neurobiological disor-
der defined by an inadequate developmental level of
Abstract: inattention, hyperactivity and impulsivity, symptoms
Historically, ADHD or Attention-deficit/hyperac- that can appear in any combination at school, at home
tivity disorder was considered to be primarily a child- or in any other social activity.
hood condition. In a recent study, Biederman shows The beginning is in childhood: according to the
that in 65% cases ADHD symptoms persist at adult definition – before the age of 7, almost always before 5,
age. Since ADHD is such a well-known disorder, adults and often before 2 years old. The disorder often persists
with both objective and subjective symptoms of poor in adolescent and adult life and is an important risk fac-
concentration and inattention have got the probabili- tor for personality disorders (4).
ties for evaluation. ADHD was first mentioned in adult life in DSM
The symptoms of ADHD change as someone with III being considered a residual disorder. In DSM III-R
ADHD develops from a child into a teenager and then it is specified that 1/3 of the adults that have been diag-
into an adult. Typically, the symptoms of hyperactivity nosed with ADHD in childhood still have ADHD
decrease with age and become more subtle, while prob- symptoms, while DSM IV affirms the persistence of the
lems related to concentration and organization become ADHD diagnosis at the adult.
more dominant. Diagnosis for adult is further compli-
EPIDEMIOLOGY
cated by the overlap between the symptoms of ADHD
and the symptoms of other common psychiatric condi- ADHD prevalence varies with each country: 0-
tions such as depression and substance abuse. 2,5% for European countries, 7-12,6% in USA, 3,3-9%
Accurate diagnosis of ADHD in adults is chal- in Canada and 7,7% in Japan (4; 5; 6; 7).
lenging and requires attention to early development, Psychologist Dr. Maria Grigoroiu ªerbãnescu par-
and symptoms of inattention, distractibility, impulsivity tially published in 1999 and then in 2001 the results of
and emotional lability. an important epidemiological study realized in our
Key words: ADHD, child, adult, life quality country (project Centaur) regarding psychic and neuro-
* Child and Adolescent Psychiatry Resident, M.D., Hospital „Prof. Dr. Alexandru Obregia”, Bucharest
** Psychiatry Resident, M.D., Hospital „Prof. Dr. Alexandru Obregia”, Bucharest
*** Neurosurgery Resident, M.D., University Emmergency Hospital, Bucharest
**** Psychiatry Professor M.D. Ph.D., University of Medicine and Pharmacy „Carol Davila” Bucharest, Hospital „Prof. Dr. Alexandru
Obregia”, Bucharest

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F. Rad, C, Constantinescu, L. Nicolae, I. Dobrescu - ADHD - from childhood to adulthood

Table 1. A historical retrospective of ADHD term (1)

Year Terms used


1902 (Still) Morbid Defect of Moral Dyscontrol
1906 (French classification) Instabilité psychomotor
1941/1947 (Strauss) Minimal Brain Damage Syndrome
1962 (Clements ºi Peters) Minimal Brain Dysfunction (MBD)
1968 (DSM II) Hyperkinetic Reaction Disorder (HRD)
1980 (DSM III) Attention Deficit Disorder with or without Hyperactivity, ADD/H, ADD without
Hyperactivity
1987 (DSM III-R) Attention Deficit/Hyperactivity Disorder (ADHD)
Undiferentiated Attention Deficit Disorder (UADD)
1994 (DSM IV) Attention Deficit/Hyperactivity Disorder
ADHD Classification:
ADHD Primarily Inattentive (ADHD-PI)
ADHD Primarily Hyperactive/Impulsive (ADHD- PHI)
ADHD combined (ADHD-C)2000 (DSM IV-TR)Attention Deficit/Hyperactivity
Disorder
ADHD Classification:
ADHD Primarily Inattentive (ADHD-PI)
ADHD Primarily Hyperactive/Impulsive (ADHD-PHI)
ADHD combined (ADHD-C)

logical disorders in children and teenagers. The study There are genetical, environmental, familial, psychoso-
took place between 1981-1984 on 14812 subjects with cial, pre and perinatal factors implied that acting on a
ages between 10 months and 16 years. The criteria used neurobiological state determine the apparition of the
were DSM-III. The actual prevalence for ADHD on age symptoms.
groups and sex varied between 0.2 – 6.77% (8). Genetical theories in ADHD
In a study on 3199 subjects aged between 18-44 ADHD is a high inheritable disorder: 75% (15).
years and that meet DSM IV criteria for ADHD Kessler According to the literature data 25-33% from the par-
et al finds 4.4% prevalence (9). ents of the ADHD children are themselves affected by
There are studies in specialty literature that show this disease (16; 17). Parents with ADHD have a 50%
that 65% of the children with ADHD continue to pres- chance to have a child with ADHD (17). Concordance
ent symptoms at adult age. ADHD prevalence at the in Concordanþa la gemenii monozigoþi este de 92% iar
adult in USA is 5% (10). la gemenii dizigoþi 33% (18).
In a meta-analysis of the studies in specialty liter- Genetic studies focused on the genes involved in
ature regarding adult ADHD Faraone et al show that the neurotransmitter function regulation (especially
persistent rate of ADHD at adult differs with the includ- dopamine and noradrenalin). The conclusion was that
ing criteria. Thus if we include in ADHD only the there is no single gene involved, but a complex of sus-
adults that have all the criteria for the disorder from ceptible genes. These have been identified and correlat-
DSM-IV, the persistence rate is 15%. If the adults that ed with ADHD: dopaminergic transporter gene
meet the criteria for ADHD in partial remission are also (DAT1), dopaminergic receptor gene D4 (DRD4),
included, persistence rate is 65% (11). dopaminergic receptor gene D5 (DRD5), SNAP 25
In a prospective study on 112 adolescents with gene that controls synaptic vesicles transmission, nora-
ADHD, Biederman found in 58% of the cases charac- drenalin transporter gene, but also genes involved in
teristic symptoms for ADHD after 10 years of evolu- serotonin transportation (19; 20; 21).
tion, compared with 6% in the control group (12). Environmental, familial and psychosocial factors
Sex ratio shows a predominance of the male sex. ADHD is associated with a series of risk factors:
Literature data show a boys/girls ratio of 2.5 -12 : 1. In pre- and perinatal disorders, small weight at birth, ante-
adult life the sex differences disappear (13; 6; 14). natal exposure to alcohol and nicotine, maternal stress
Considering the age groups prevalence is higher during pregnancy, maternal metabolic disorders, head
for pre-school and early school children. trauma, meningitis and encephalitis. ADHD is correlat-
ed with early maternal abandon and institutionalization,
ETIOPATHOGENY
with a chaotic social environment and also other psy-
The exact etiopathogenic model of ADHD is still chosocial factors. The positive quality of intrafamilial
unknown. ADHD is an extremely heterogenic disorder. relationships is considered to be a protection factor (22;

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Revista Românã de Psihiatrie, seria a III-a, vol. X, nr. 3-4, 2008

23). CHILD ADHD SYMPTOMS


ADHD is the most frequent disorder in children
According to the diagnosis manuals DSM IV-TR
and adolescents with parents affected by: major affec-
and ICD 10 it is necessary that the symptoms of inat-
tive diseases, schizo-affective disorders, schizophrenia
tention and/or hyperactivity and impulsivity have per-
and alcoholism (24).
sisted for at least 6 months to a degree that is maladap-
Neurotransmitters involved in ADHD etiopathogeny tive and inconsistent with developmental level. Some
ADHD can be considered to be a disorder of the of the symptoms appear before the age of 7 and are
neurotransmitter function, mostly involved being present both at home and at school.
dopamine and noradrenalin. Cathecolamines have an
Inattention symptoms
important role in normal attention maintaining. Areas
z fails to give close attention to details or makes
rich in cathecolamines are involved in ADHD phys-
careless mistakes
iopathology (25). Thus the posterior systems involved
z has difficulty sustaining attention in tasks or play
in attention changing and focusing towards new stimu-
z does not seem to listen when spoken to directly
lus (mediated by NA), and anterior system (mediated
z does not follow instructions and fails to finish
by DA and NA) involved in data analysis and answer
schoolwork
preparation are affected.
z has trouble organizing activities
Neuroanatomy and ADHD z voids, dislikes, or doesn’t want to do things that
Neuroimagistic studies show anomalies in frontal, take a lot of mental effort for a long period of time
temporal and parietal lobes (cortical regions), basal z loses things needed for tasks and activities
ganglia and cerebellum. These anomalies are preco- z Is often easily distracted
cious and non-progressive. z Is often forgetful in daily activities
ADHD pacients have a cerebral volume signifi-
Hyperactivity symptoms
cantly lower in these regions: cerebellar volume, basal
z dgets with hands or feet or squirms in seat
ganglia, cerebellar vermis, prefrontal right cerebral cor-
z gets up from seat when remaining in seat is
tex, globus pallidus. At ADHD children cerebral total
expected
volume is 3.2% lower and cerebellar volume is 3.5%
z runs about or climbs when and where it is not
lower compared to control. In the frontal region it has
appropriate (adolescents or adults may feel very rest-
been demonstrated a reduction in white matter volume,
less)
especially in the right hemisphere. Also it has been
z has trouble playing or enjoying leisure activities
showed a reduction of the gray matter in both hemi-
quietly
spheres, but more in the right one. These anomalies per-
z is often „on the go“ or often acts as if „driven by
sist in time. The cerebral volume is correlated with
a motor“
ADHD severity (27).
z talks excessively
In a 2006 study Shaw pointed out to a global thin-
ning of the cortex in ADHD children compared to con- Impulsivity symptoms
trol, especially in prefrontal and precentral, superior z blurts out answers before questions have been

and medial regions that are important in attention con- finished


trol (28). z has trouble waiting one’s turn

Prefrontal cortex, involved in executive functions z interrupts or intrudes on

(planning, organizing, initiation or delaying of the DSM IV-TR describes 3 subtypes of ADHD based
answers), in working memory and cognition modula- on the dominant symptom pattern in the last 6 months:
tion, is dysfunctional in ADHD. Neuroimagistic studies Combined Type: inattention and hyperactivity-
demonstrate that prefrontal right cortex is smaller in impulsivity symptoms
ADHD patients (29). Also anomalies have been Predominantly Inattentive Type: inattention
showed at the level of anterior cingular cortex involved symptoms
in stimulus selection and answer inhibition (30). Predominantly Hyperactive-Impulsive Type:
hyperactivity-impulsivity symptoms
Neuropsychological profiles
In children hyperactive-impulsive or combined
There are more neuropsychological mechanisms
types are dominant (3).
in ADHD: prefrontal inhibitory function deficits, work
memory and selective attention dysfunction, timing ADULT ADHD SYMPTOMS
deficit, energetic status and particular personality traits
The symptoms of ADD / ADHD change as some-
deficiency (31).
one with ADD / ADHD develops from a child into a
The “reward” circuits are also affected: decrease
teenager and then into an adult. While the core prob-
of tolerance to aversion and decrease of the waiting
lems of hyperactivity, impulsiveness, and inattentive-
time (ADHD child can’t wait patiently for his reward).
ness remain the same, the specific symptoms manifest
According to Biederman at the adult with ADHD cog-
differently. Typically, the symptoms of hyperactivity
nition and emotional affecting is maintained.
decrease and become more subtle, while problems

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F. Rad, C, Constantinescu, L. Nicolae, I. Dobrescu - ADHD - from childhood to adulthood

related to concentration and organization become more able to “hyperfocus” for long periods of time on tasks
dominant. or projects that they find interesting. This is particular-
Hyperactivity in adults: ly true of interactive or hands-on activities. They may
z inability to relax even be compulsive about it, spending hours immersed
z restlessness, nervous energy in the activity without a thought to anything or anyone
z overwhelmed by “urgent tasks” else (32).
z working on many activities at the same time Positive characteristics of adults with ADD / ADHD
z insomnia, irascibility The symptoms of ADD / ADHD are not all nega-
z active job tive. People with ADD / ADHD also have many posi-
z talking excessively tive traits that are directly tied to their active, impulsive
Impulsiveness in adults: minds:
z answers before without hearing whole question z Creativity – People with ADD excel at thinking

z blurting out rude or insulting remarks outside of the box, brainstorming, and finding creative
z interrupting others solutions to problems. Because of their flexible way of
z often changes his job thinking about things, they tend to be more open-mind-
z drives with excessive speed ed, independent, and ready to improvise.
z volatile moods z Enthusiasm and spontaneity – People with

Inattentiveness in adults: ADD are free spirits with lively minds—qualities that
z “tuning out” unintentionally makes for good company and engrossing conversation.
z inability to focus on mundane tasks Their enthusiasm and spontaneous approach to life can
z slow, inefficient be infectious.
z has issues with time management z A quick mind - People with ADD have the abil-

z difficulties with finishing activities ity to think on their feet, quickly absorb new informa-
z often does not listen when talking directly to him tion (as long as it’s interesting), and multitask with
z constantly losing and forgetting things ease. Their rapid-fire minds thrive on stimulation. They
Also at the adult there are 3 sub-types of ADHD: adapt well to change and are great in a crisis.
Hyperactive-Impulsive Type: hyperactivity- z High energy level – People with ADD have

impulsivity symptoms dominant for at least last 6 loads of energy. When their attention is captured by
months. something that interests them, they can have virtually
Inattentive Type: inattention symptoms present unlimited stamina and drive (33).
for the last 6 months. Negative effects of ADHD on adult life:
Combined Type: both inattention and hyperactivi- Left untreated, ADD can wreak havoc in your life,
ty-impulsivity symptoms for the last 6 months. disrupting everything from your career to your social
If in children hyperactive-impulsive type is domi- life, love life, and financial stability (34).
nant, in adults dominates the inattentive type (32). Professional life: ADD / ADHD can be a big
According to Dr. Thomas E. Brown (cited by stumbling block on the road to career success. The
Smith) of the Yale University School of Medicine, symptoms of disorganization and inattention, in partic-
„ADHD is essentially a name for developmental ular, pose problems in the workplace. If you have ADD
impairment of executive function.“ Executive functions / ADHD, you may:
are the skills involved in planning, selective attention, z be chronically late to work,
motivation, and impulse control. Adults with ADHD z miss or forget deadlines and meetings,
have problems in six major areas of executive function- z have a hard time organizing projects and dele-
ing: gating work,
z Activation – Problems with organization, priori- z have difficulty completing projects on time,
tizing, and starting tasks. z spend hours at work, but get very little done,
z Focus – Problems with sustaining focus and z get distracted by trivial tasks, while neglecting
resisting distraction, especially with reading. the most important ones,
z Effort – Problems with motivation, sustained z have trouble paying attention in meetings or in
effort, and persistence. conversations with your boss and colleagues.
z Emotion – Difficulty regulating emotions and Relationships: ADD / ADHD can put a strain on
managing stress. your relationships. The chaos that surrounds the disor-
z Memory – Problems with short-term memory der is particularly hard on romantic relationships. The
and memory retrieval. spouse or partner without ADD may feel resentful if he
z Action – Problems with self-control and self- or she is the one who has to take care of all the plan-
regulation. ning, organizing, cleaning, bill paying, and other house-
While adults with ADHD have great difficulty hold responsibilities. And you may resent your part-
maintaining attention, those same individuals often are ner’s constant nagging to tidy up, get organized, and

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take care of business. Friends and family members may ADHD IMPACT ON DEVELOPMENT
also take it personally when you tune them out, forget
ADHD interferes with development and social
conversations or commitments, speak a little too blunt-
function and leads to the apparition of other disorders.
ly, or keep them waiting.
A pre-school child can frequently have behavior disor-
Finance: The ADD / ADHD symptoms of pro-
ders. School children can have conduct disorders,
crastination, disorganization, and impulsivity can inter-
school issues, social interaction difficulties and low
fere with good money management. If you have ADD /
self-esteem. Adolescents and students can have law and
ADHD, you may find that you:
smoking problems, while at the adult life professional
z forget to pay bills,
failure, low self-esteem, substance abuse and relation-
z run up huge balances on your credit cards,
ship problems can be real issues (36).
z cannot save money,
ADHD has an important impact on daily activities,
z are unable to follow through on long-term finan-
school results and work performance. In a study which
cial goals,
included 500 subjects diagnosed with ADHD with ages
z shop impulsively,
between 18 and 64 years (done by Biederman in USA)
z have difficulty keeping financial paperwork in
was pointed out a lower income at the adults with
order, and
ADHD (10).
z fail at budgeting and recordkeeping.
TREATMENT
Eating behaviors: The impulsivity of ADD /
Main ADHD symptoms have consequences in
ADHD can extend to eating, and many adults with the
multiple areas determining school, home and social
condition also suffer from overeating, obesity, or disor-
dys-functionality. Main treatment targets are the opti-
dered eating. talks about the connection between
ADHD (ADD) and disordered eating: If you have ADD mization of child function in these areas (37).
/ ADHD, you may: MTA Cooperative Group (1999) established that in
z eat snacks throughout the day, rather than eating
ADHD most efficient therapeutic strategies for symp-
at planned meals, tom suppression are those based on medication and
z be unable to stick with a diet,
those combined: medication and behavior intervention.
z have intense cravings for carbohydrates and caf- Medical therapy must be taken in consideration
feine (in coffee and chocolate), when the patient meets the DSM IV criteria for ADHD
z eat a lot of fast food and “junk food” (cookies, and the criteria for primary use of medication are met,
chips, soda, fries, ice cream), or psychological treatment by itself is insufficient.
z ignore hunger signs, waiting until you’re too There are numerous studies that documented in
hungry to plan a healthy meal and then eating whatev- time the efficacy of the stimulant medication, which
er you can find (34). rapidly reduces hyperactivity, inattention and impulsiv-
ADHD AND COMORBIDITY ity. They improve the functionality in multiple domains
both on short and on long term (4). Stimulant medica-
Children and adults with ADHD frequently meet tion includes short time and long time action drugs.
the criteria of one or more psychiatric diagnosis. 65% Psycho-stimulant medication works at the level of
of the children with ADHD have the condition of some the prefrontal cortex on noradrenergic and dopaminergic
comorbidities. 85% of the newly diagnosed ADHD circuits. Also it works at the level of the striate, where it
cases associated a comorbid disorder and 60% associ- binds to the dopamine transporter and increases the
ate 2 comorbid disorders (35). dopamine quantity from the synaptic gap. This way
In children most frequent disorders that are comor- Metilfenidat allows the inhibitory circuits to fulfil their
bid with ADHD are: oppositional defiant disorder, con- role decreasing the hyperactivity and impulsivity (40).
duct disorders, autism spectrum disorder (50-80% from Stimulant medication is approved and used in the
the young children with ASD have ADHD symptoms), majority of the European countries and in USA. In our
learning disorders, anxiety disorders, obsessive-com- country Metilfenidat with slow release (Concerta) has
pulsive disorder, depression, enuresis, tics, Tourette been approved for the treatment of the children with
disorder, bipolar disorder, sleep disorder and accidental ADHD in 2007.
lesions (35). Non-stimulant specific medication is represented
Many of the comorbidities met in children are still by Atomoxetine, a new drug, specific inhibitor of norep-
present at adult life. Most frequent are: obsessive-com- inephrine reuptake (it inhibits the presinaptic transporter
pulsive, depressive, bipolar, sleeping and anxiety disor- of norepinephrine. It has low affinity for other noradren-
ders, and substance abuse (9). ergic receptors or for other transporters. Atomoxetine
In a prospective study, Biederman et al, showed affects in a lower degree the dopaminergic system.
after 10 years of evolution a high prevalence of antisocial Dopamine levels are not increased in the accumbens
behavior, anxiety and disposition disorders and nicotine, nucleus or in the striate. Atomoxetine is correlated with
alcohol and drug abuse in young people when compared increased levels of dopamine in the prefrontal cortex –
with the control group. Comorbid disorders increase hos- region responsible for working memory, the ability to
pitalization costs of the ADHD patients (10). repeat answers and the impulsivity level (1).

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F. Rad, C, Constantinescu, L. Nicolae, I. Dobrescu - ADHD - from childhood to adulthood

At the adult the clinical experience proves that The European Guide for ADHD recommends the use of
there is an important benefit from the stimulant therapy both types of medication at the adult, both for those
and from the non-stimulant specific one (Atomoxetine). who initiated the treatment in childhood and for those

Jasper/Goldberg Adult ADD/ADHD Screening Quiz (by Larry Jasper & Ivan Goldberg)
1. At home, work, or z Moderately z Quite a lot z Quite a lot
school, I find my mind z Quite a lot z Very much z Very much
wandering from tasks z Very much 13. I almost always am on 19. In group activities it is
that are uninteresting or 7. I make quick decisions the go. hard for me to wait my
difficult. without thinking enough z Not at all turn.
z Not at all about their possible bad z Just a little z Not at all

z Just a little results. z Somewhat z Just a little

z Somewhat z Not at all z Moderately z Somewhat

z Moderately z Just a little z Quite a lot z Moderately

z Quite a lot z Somewhat z Very much z Quite a lot

z Very much z Moderately 14. I am more comfortable z Very much

2. I find it difficult to read z Quite a lot when moving than 20. My mind gets so clut-
written material unless it z Very much when sitting still. tered that it is hard for
is very interesting or 8. My relationships with z Not at all it to function.
very easy. people are made diffi- z Just a little z Not at all
z Just a little
z Not at all cult by my tendency to z Somewhat
z Somewhat
z Just a little talk first and think later. z Moderately
z Moderately
z Somewhat z Not at all z Quite a lot
z Quite a lot
z Moderately z Just a little z Very much
z Very much
z Quite a lot z Somewhat 15. In conversations, I start
z Very much z Moderately to answer questions 21. My thoughts bounce
3. Especially in groups, I z Quite a lot before the questions around as if my mind
find it hard to stay z Very much have been fully asked. is a pinball machine.
z Not at all
focused on what is 9. My moods have highs z Not at all
z Just a little
being said in conversa- and lows. z Just a little
z Somewhat
tions. z Not at all z Somewhat
z Moderately
z Not at all z Just a little z Moderately
z Quite a lot
z Just a little z Somewhat z Quite a lot
z Very much
z Somewhat z Moderately z Very much
22. My brain feels as if it
z Moderately z Quite a lot 16. I usually work on more
is a television set with
z Quite a lot z Very much than one project at a all the channels going
z Very much 10. I have trouble planning time, and fail to finish at once.
4. I have a quick temper... in what order to do a many of them. z Not at all
a short fuse. series of tasks or activ- z Not at all
z Just a little
z Not at all ities. z Just a little
z Somewhat
z Just a little z Not at all z Somewhat
z Moderately
z Somewhat z Just a little z Moderately
z Quite a lot
z Moderately z Somewhat z Quite a lot
z Very much
z Quite a lot z Moderately z Very much
23. I am unable to stop
z Very much z Quite a lot 17. There is a lot of „stat- daydreaming.
5. I am irritable, and get z Very much ic“ or „chatter“ in my z Not at all
upset by minor annoy- 11. I easily become upset. head. z Just a little
ances. z Not at all z Not at all z Somewhat
z Not at all z Just a little z Just a little z Moderately
z Just a little z Somewhat z Somewhat z Quite a lot
z Somewhat z Moderately z Moderately z Very much
z Moderately z Quite a lot z Quite a lot 24. I am distressed by the
z Quite a lot z Very much z Very much disorganized way my
z Very much 12. I seem to be thin 18. Even when sitting qui- brain works.
6. I say things without skinned and many etly, I am usually mov- z Not at all
thinking, and later regret things upset me. ing my hands or feet. z Just a little
having said them. z Not at all z Not at all z Somewhat
z Not at all z Just a little z Just a little z Moderately
z Just a little z Somewhat z Somewhat z Quite a lot
z Somewhat z Moderately z Moderately z Very much

The answers to the above questions have a corresponding score as follows:


0. Not at all; 1. Just a little; 2. Somewhat; 3. Moderately; 4. Quite a lot; 5. Very much

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Revista Românã de Psihiatrie, seria a III-a, vol. X, nr. 3-4, 2008

that are starting the treatment for the first time (41). 3. American Psychiatric Association. Manual de diagnostic si
Psycho-educational measures: counseling and statistica a tulburarilor mentale, editia a IV-a revizuita - DSM-IV-TR
2000. Bucuresti, Ed. Asociatia Psihiatrilor Liberi din România, 2003,
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