Acetaminophen use during pregnancy increases risk of preeclampsia, hypertensive and vascular disorders: a birth cohort study. Researchers selected 63,833 women participating in the Danish National Birth Cohort who gave birth to a live born singleton. Women who used the drug during the third trimester of pregnancy had a higher risk of gestational hypertension, thromboembolic complications, or abruptio placentae.
Acetaminophen use during pregnancy increases risk of preeclampsia, hypertensive and vascular disorders: a birth cohort study. Researchers selected 63,833 women participating in the Danish National Birth Cohort who gave birth to a live born singleton. Women who used the drug during the third trimester of pregnancy had a higher risk of gestational hypertension, thromboembolic complications, or abruptio placentae.
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Acetaminophen use during pregnancy increases risk of preeclampsia, hypertensive and vascular disorders: a birth cohort study. Researchers selected 63,833 women participating in the Danish National Birth Cohort who gave birth to a live born singleton. Women who used the drug during the third trimester of pregnancy had a higher risk of gestational hypertension, thromboembolic complications, or abruptio placentae.
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Attribution Non-Commercial (BY-NC)
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Download as DOCX, PDF, TXT or read online from Scribd
Preeclampsia; Scientists at Municipal Institute of Medical Research report
research in preeclampsia Anonymous. Hematology Week. Atlanta: Jun 7, 2010. pg. 520 Abstract (Summary)
2010 JUN 7 - (<http://www.newsrx.com> NewsRx.com) -- A new study, 'Use of acetaminophen during
pregnancy and risk of preeclampsia, hypertensive and vascular disorders: a birth cohort study,' is now available (see also <http://www.newsrx.com/library/topics/Preeclampsia.html> Preeclampsia). "To examine whether pregnant women who used acetaminophen, a prostaglandinG2 synthase inhibitor, had an increased risk of preeclampsia, gestational hypertension, thromboembolic complications, or abruptio placentae. We selected 63,833 women participating in the Danish National Birth Cohort who gave birth to a live born singleton and had information on acetaminophen use during pregnancy reported by three interviews," researchers in Barcelona, Spain report.
xFull Text (331 words) (c)Copyright 2010, Hematology Week via NewsRx.com
2010 JUN 7 - (<http://www.newsrx.com> NewsRx.com) -- A new study, 'Use of acetaminophen during
pregnancy and risk of preeclampsia, hypertensive and vascular disorders: a birth cohort study,' is now available (see also <http://www.newsrx.com/library/topics/Preeclampsia.html> Preeclampsia). "To examine whether pregnant women who used acetaminophen, a prostaglandinG2 synthase inhibitor, had an increased risk of preeclampsia, gestational hypertension, thromboembolic complications, or abruptio placentae. We selected 63,833 women participating in the Danish National Birth Cohort who gave birth to a live born singleton and had information on acetaminophen use during pregnancy reported by three interviews," researchers in Barcelona, Spain report. "Through linkage to the National Hospital Discharge Registry we obtained data from hospital diagnose of the outcomes we study. Women who used acetaminophen during the third trimester of pregnancy had an increased risk of preeclampsia (adjusted relative risk RR=1.40, 95% CI: 1.24-1.58). The risk was higher among women who had early preeclampsia (before the 32nd gestational week) (RR=1.47, 95% CI: 1.12-1.93), severe preeclampsia (RR=1.51, 95% CI: 1.15-2.00), or chronic hypertension (RR=1.44, 95% CI: 1.13-1.83). Second and third trimester use was associated with an increased risk of pulmonary embolisms (RR=3.02, 1.28-7.15) and deep vein thrombosis (RR=2.15, 1.06-4.37), respectively," wrote C. Rebordosa and colleagues, Municipal Institute of Medical Research. The researchers concluded: "Acetaminophen use during pregnancy is associated with an increased risk of diseases in which a reduction of prostacyclin during pregnancy has been postulated to play a role, including preeclampsia and thromboembolic diseases." Rebordosa and colleagues published their study in the Journal of Maternal-fetal & Neonatal Medicine (Use of acetaminophen during pregnancy and risk of preeclampsia, hypertensive and vascular disorders: a birth cohort study. Journal of Maternal-fetal & Neonatal Medicine, 2010;23(5):371-8). For additional information, contact C. Rebordosa, Municipal Institute of Medical Research (IMIM-Hospital del Mar), Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain. Keywords: City:Barcelona, Country:Spain, Acetaminophen, Acetanilides, Cardiovascular Diseases, Eclampsia, Hospital, Hypertension, Preeclampsia, Vascular Diseases. This article was prepared by Hematology Week editors from staff and other reports. Copyright 2010, Hematology Week via <http://www.newsrx.com> NewsRx.com. 305 PQ REVERSE_CHRO 1294136681
Indexing (document details)
People: Rebordosa, C Author(s): Anonymous Document types: Expanded Reporting Publication title: Hematology Week. Atlanta: Jun 7, 2010. pg. 520 Source type: Periodical ISSN: 15436721 ProQuest document 2047872701 ID: Text Word Count 331 Document URL: http://proquest.umi.com/pqdweb? did=2047872701&sid=8&Fmt=3&clientId=71572&RQT=309&VName=P