Name Mechanism of Indication Contraindication Adverse Effect Nsg.

Resp
Action
GN: Ethambutol -Ethambutol -Initial phase Hypersensitivity. -Disorders of the -Perform visual
BN: Myrin P interferes with treatment & re- Alcoholism, optic blood & lymphatic acuity and
Forte RNA synthesis, treatment of all neuritis, impaired system, immune color
D: 3 tab OD in 5 causing forms of TB in hepatic function, system, descrimination
to 7 days before suppression of category I & II severe renal metabolism & test before and
breakfast. Mycobacteria patients caused by insufficiency, nutrition, CNS, during the
multiplication. It susceptible strains hyperuricemia, eye, GI, therapy.
also has of mycobacteria. gouty arthritis, hepatobiliary, -Assess liver
bacteriostatic jaundice, skin & SC tissues, and renal
action against M retrobulbar musculoskeletal, function before
tuberculosis by neuritis. Pregnancy connective tissue and during the
acting on rapidly & lactation. & bone, therapy.
growing renal/urinary, -Assess patient
pathogens in reproductive mental status
cavity walls and system & breast. often: affect
is also effective Fever, malaise, mood,
in slow-growing flu-like syndrome, behavior
pathogens. dryness of mouth. change. watch
out for
confusion and
hallucination
-Assess patient
for visual
disturbance
that may
indicate optic
neurisyis
GN: -Pregnancy;
Streptomycin -Part of combination hypersensitivity
BN: therapy of active -Abnormal skin
Streptomycin -Inhibits protein tuberculosis; use in sensation around
D: 1G IM synthesis in combination with the face; vertigo;
bacterial cell by other agent for fever -Assess patient
building direct to treating of -Severe allergic with previous
30S ribosomal streptococcus or reactions (rash; sensitivity
subunits, causing enterococcal hives; difficulty reaction.
inaccurate endocarditic, breathing; -Assess patient
peptide mycobacterial tightness in the with signs and
sequence to form infection, plague, chest; swelling of symptoms of
In protein chain, tularemia, and the mouth, face, infection
resulting in brucellosis lips, or tongue); including
bacterial death. decreased characteristic
urination; of sputum,
dizziness; urine, stool,
headache; WBC>10,000/
hearing loss; mm3
hives; -Obtain
lightheadedness; baseline
loss of balance; information
muscle weakness; before and
nausea; during
numbness or treatment
tingling; ringing -Identify urine
or roaring in the output, If
ears; skin rash or decrease,
itching; vaginal notify
irritation or physician.
discharge; -Assess over
vomiting growth of
infection:
perineal
-Hypersensitivity itching, fever
to quinolones. IV redness, pain
GN: Epilepsy, history of swelling,
-Levofloxacin - Treatment of tendon disorders drainage, rash,
BN: -Levaquin adults ≥18 yr w/ related to diarrhea, chain
-Quixin -The levorotatory mild, moderate & fluoroquinolone in cough
D: -500 mg OD isomer of severe infections therapy. Childn, sputum.
ofloxacin which caused by pregnancy & -Monitor input
inhibits DNA susceptible strains lactation. and output,
topoisomerase, of microorganisms report sudden
more commonly in the following change
referred to as the conditions: - Diarrhea,
DNA gyrase. DNA Community- abdominal
gyrase is acquired discomfort, - Store in a dry
necessary for pneumonia, acute nausea, anorexia, place at
bacterial DNA bacterial abdominal pain, temperatures
replication and exacerbation of vomiting, not more than
some aspects of chronic bronchitis, stomatitis & 30°C.
transcription, acute maxillary heartburn; - Should be
repair, sinusitis, insomnia, used with
recombination complicated & headache & caution in
and uncomplicated skin dizziness; rash, patients with a
transposition. & skin structure pruritus & known or
Inhibition of DNA infections, acute eczema; muscle suspected CNS
gyrase in pyelonephritis, & joint pain; bone disorder that
susceptible complicated & marrow may
microorganisms uncomplicated UTI, depression. predispose to
results in the nosocomial Increased liver seizures or
inhibition of ATP- pneumonia, chronic enzymes. Pain, lower seizure
dependent bacterial prostatitis. reddening at the threshold
negative inj site, phlebitis. -Take the oral
supercoiling of solution 1 hr
DNA, inhibition of before or 2 hrs
ATP-independent after eating.
relaxation of -Avoid
supercoiled DNA multivitamins
and promotion of Patients receiving with zinc, iron
GN: double-stranded astemizole, products,
-Clarithromycin DNA breakage cisapride, sucralfate, and
BN: -BiaxinXL resulting in dihydroergotamine Mg- or Al-
D: - Tablets, ER bacterial cell , ergotamine, containing
500 mg death. pimozide, or antacids 4 hr
terfenadine; before and
Treatment of hypersensitivity to after dose.
pharyngitis/tonsilliti clarithromycin,
s; acute maxillary erythromycin, or
sinusitis; acute any macrolide
Clarithromycin is bacterial antibiotic.
a semi- synthetic exacerbation of
macrolide chronic bronchitis;
antibiotic community- Abdominal pain,
chemically acquired diarrhea, nausea, -Advise patient
related pneumonia; vomiting. to review the
to erythromycin. uncomplicated skin patient
It is effective and skin structure information
against a wide infections; leaflet carefully
variety of disseminated before starting
bacteria mycobacterial therapy and to
organisms, such infections; read and check
as Haemophilus Helicobacter pylori for new
influenzae, and duodenal ulcer information
Streptococcus disease when used each time the
pneumoniae, in combination with medication is
Mycoplasma amoxicillin and refilled.
pneumoniae, lansoprazole or -Advise patient
Staphylococcus omeprazole; H. taking
aureus, pylori and active immediate-
and mycobacteri duodenal ulcer release tablets
um avium, and when used in or oral
many others. combination with suspension
omeprazole or that
ranitidine bismuth medication can
citrate; prevention be taken
of disseminated without regard
 Mycobacterium to meals, but
avium complex to take with
GN: (MAC) disease in food if GI upset
-Streptomycin patients with Allergy to occurs.
BN: advanced HIV aminoglycosides, - Advise
-Streptomycin infection; treatment pregnancy, patient to
D: 1g IM of disseminated lactation, Herpes report the
mycobacterial vacinia fungal following signs
infections caused infection. of
by M. avium or superinfection
Mycobacterium to health care
intracellulare . provider:
black, “furry”
tongue; foul-
Vestibular smelling
Inhibits CHON Infections caused ototoxicity (eg, stools; vaginal
synthesis strains by susceptible nausea, vomiting, itching or
of gram negative strain of vertigo); cochlear discharge;
bacteria, mycobacterium ototoxicity white patches
mechanisms of tuberculosis. (deafness); in mouth.
lethal action and Serious infections c amblyopia.
fully understood, aused by
but functional susceptible strains
integrity of cell of Yersinia Pestis
membrane
appears to be Use in route
GN: -Amikacin disrupted. Renal impairment, only: give by
BN: -Amikin Hearing deep IM
D: 900mg IV OD imparement, injection.
Geriatic patient
and premature Use in route
infants, Obese only: give by
patient, deep IM
Pregnancy. injection.
GN:
-Clindamycin Monitor for
BN: -Cleocin Hypersensitivity, hearing
D: 600mg IV previous changes.
pseudomembrano Ototoxicity,
Inhibits protein Treatment of us colitis. nephrotoxicity, This drug can
synthesis in serious gram- Muscle paralysis, only be given
bacteria at level negative bicallary Severe liver Hypersensiticity. by injection.
of 30s ribosome. infections and impairment,
infections caused Diarrhea. known Report hearing
by staphylococci alcohol changes,dizzin
when penicillins or intolerance. ess, pain at
other less toxic Dizziness, injection site,
GN: -Cefepime Inhibits protein drugs are Headache, rash.
BN: -Maxipime synthesis in contraindicated. Vertigo.
D: 2g IV susceptible Hypersensitivity to
bacteria at the Treatment of skin cephalosporins.
level of the 50s and skin structure serious Assess for
ribosomes infections, hypersensitivity to infection at
respiratory tract penicillins. beginning of
infections, and
septicema, intra- throughout
abdominal therapy.
infections,gynecolo
gic infections,
osteomylitis, Seizures,
Blind to the endocarditis Pseudomembrano Assess for
GN: -Cefoxitin bacterial cell wall prophylaxis. us, colitis, infection
BN: -Mefoxin membrane, diarrhea, nausea, appearance of
D: 1g IM,IV causing cell vomiting, cramps, wound,
death. Hypersensitivity to jaundice sputum, urine
cephalosporins. and stool at
Treatment of skin serious beginning of
structure infections, hypersensitivity to and during
bone and join penicillins. theraphy.
infections, urinary
and gynecologic
infections including
 gonorrhea or
respiratory tract
GN: -Linezolid infections, intra- Seizures, Observe
BN: -Zyvox abdominal Pseudomembrano patient for
Blind to the infections, us, colitis, signs and
bacterial cell wall septicemia, otitis diarrhea, nausea, symptoms of
membrane, media. Thrombocytopenia vomiting, cramps, rash, puritus,
causing cell , concurrent use of jaundice laryngeal
death. anti platelet edema,
agents or bleeding wheezing.
diathesis. discontinue the
drug and notify
Treatment of the physician if
respiratory tract these
infections, Skin and symptoms
GN: -Kanamycin skin structure occur.
BN: -Kantrex infections, Bone and Headache,
D: 1.5g IM,IV joint infections, insomnia,
urinary tract and pseudomembrano
Inhibits bacterial gynecologic us colitis,
protein synthesis infection, Renal impairment, diarrhea, Observe
at the level of the septicemia. Hearing increased liver patient for
23s ribosomes of imparement, function tests, signs and
the 50s subunit. Geriatic patient nausea, test symptoms of
bacteridicidal and premature alteration rash, puritus,
GN: action against infants, Obese vomitting. laryngeal
-Meropenem strepcocci; patient, edema,
BN: -Merrem bacteriostatic Pregnancy. wheezing.
D: 1g IV action against Treatment of discontinue the
enter-cocci and infections caused drug and notify
staphylococci. by vancomyci- the physician if
resistance these
enterococcus Hypersensitivity to Ototoxicity, symptoms
faecium meropenem or nephrotoxicity, occur.
Inhibits protein complicated skin imipenem. serious Muscle paralysis,
synthesis in structure infections hypersesitivity to Hypersensiticity.
 bacteria at level caused by other beta-
of 30s ribosome. staphylococcus lactams(penicillins Assess for
aureus. ). infection
appearance of
wound,
sputum, urine
Seizures, and stool at
Dizziness, beginning of
Binds to bacterial headache, Apnea and during
cell wall, Treatment of Pseudomembrano theraphy.
resulting in cell serious gram- us colitis,
death. negative bicallary constipation,
meropenem infections and diarrhea,
resists the infections caused glossitis,
actions of many by staphylococci nausea.thrush,
enzymes that when penicillins or vommiting.
GN: -Imipenem degrade most other less toxic Assess for
BN: -Primaxin other penicillins drugs are infection at
D:IV and penicillin-like contraindicated. beginning of
anti-infectives. and
throughout
therapy.
Treatment of intr-
abdominal Previous history of
infections, bacterial multiple
meningitis. skin and hypersensitivity
skin structure reactions; seizures
infections. disorders; geriatric Obtain history
patients; renal before
impairment, initiating
pregnancy, therapy to
lactation or determine
children. previous use
and reactions
to penicillins.
Seizures, persons with
 Dizziness negative
Combination with Somnolence, history of
cilastatin Hypotension, penicillin
prevents renal Pseudomembrano sensitivity may
inactivation of us Colitis, still have an
imipenem, Diarrhea, Nausea, allergic
resulting in high Vomimitng. response.
urinary
concentrations. Observe
imipenem resists patient for
the actions of signs and
many enzymes symptoms of
that degrade anaphylaxis.
most other Treatment of lower discontinue the
penicillins and respiratory tract drug and notify
penicillin-like infections, urinary physician
anti-infectives. tract infections, immediately if
abdominal these
infections, symptoms
gynecologic occur.
infections, skin and
skin structure
infections, bone and
joint infections, Do not confuse
bacteremia, imipenem with
endocarditis, omnipenem.
polymicrobic
infections. Caution patient
to notify health
care
professional if
fever and
diarrhea occur,
especially if
stool contains
blood, pus, or
mucus. advise
patient not to
treat diarrhea
without
consulting
health care
professional.
may occur up
to several
weeks after
discontinuation
of medication.