You are on page 1of 16

Copyright © eContent Management Pty Ltd. Contemporary Nurse (2009) 31: 176–189.

S tudent’s
CORNER

Prevalence, risk factors, consequences and


strategies for reducing medication errors
in Australian hospitals: A literature review

ABSTRACT The purpose of this paper is to examine medication errors in Australian hospitals
from a nursing perspective.This paper provides a detailed review of past and
current literature to examine prevalence rates and risk factors for medication
errors. It also describes unintended injury or harm, also known as adverse events,
associated with a medication error, and proposes strategies to counteract them.
According to the literature, approximately two percent of patients in an acute
hospital setting will experience a medication error.Administration of medications
has remained a high risk task for registered nurses, and for this reason, the
strategies to reduce error discussed in this paper will be predominantly nursing
focussed.The occurrence of a medication error is a significant issue in the health
Key Words care setting, and although the relative risk of an individual error occurring
nursing; is low, the rate of error remains perceivably high in clinical practice today.
medication With continual technological and pharmaceutical advances, the medication
error; adverse
administration environment is becoming increasingly complex. Given the nature

CN
event; drug;
patient safety; of medication therapy, it is near impossible to avoid all error, human and
risk otherwise.
Received 7 February 2008 Accepted 11 February 2009

INTRODUCTION
n the clinical setting, all too frequent errors
I in the administration of medications are a
persistent problem. As registered nurses have
the responsibility of the final contact with the
JENNIFER EVANS medication prior to administration, they are
Undergraduate student often held accountable for subsequent adverse
Deakin University –
Burwood Campus
events. Administering a medication is the nurs-
Melbourne VIC, Australia ing task that carries the highest risk, and the

176 CN Volume 31, Issue 2, February 2009


Student corner: Strategies for reducing medication errors in Australian hospitals CN
consequences of an error can be devastating for the essential benefits of therapy for patient safe-
the patient and the nurse (Anderson & Webster ty (Helper & Segal 2003).
2001). Patient safety can be defined as the avoidance
As well as being a high risk task for nurses, it or reduction of actual or potential harm to a
is also worth considering that in Australia it has patient in a health care environment (ACSQH
been reported that about 59 percent of the pop- 2004). Medication errors jeopardise the wellbe-
ulation are currently taking prescription medica- ing and safety of patients, therefore it is an
tion (Joanna Briggs Institute 2006). So although important consideration in the current context.
the probability of a single adverse drug event According to Fogarty and McKeon (2006),
occurring is relatively low, the likelihood of such medication errors are a leading cause of patient
an event occurring remains a significant issue harm.The goal of every health care organisation
due to the high proportion of people taking is the continual improvement of systems to pre-
medications (Australian Commission on Safety vent patient harm, and the monitoring of med-
and Quality in Healthcare [ACSQH] 2004). ication errors and potential errors is a large
This paper will examine the issue of medica- component of such improvement (NCC MERP
tion errors in an Australian clinical context. It 2002). Health care facilities need to monitor
will describe the prevalence, risk factors and medication errors and investigate causes to
adverse events relating to medication errors. identify strategies for improvement of medica-
Many health facilities have implemented strate- tion practices, ensuring maximal patient safety.
gies to reduce the number of medication errors. In developing appropriate monitoring systems,
A discussion of the key aspects of these strate- it is important to recognise that blaming and
gies is provided, focussing on nursing priorities. punishing individuals for making errors does
not resolve the underlying cause of the error.
BACKGROUND The analysis of the information and data received
An adverse drug event is defined as an incident from reporting and subsequent actions has the
which actually caused harm or injury to a potential to increase patient safety.
patient, and can result from an adverse reaction Previous literature on adverse outcomes of
to a medication or a medication error (ACSQH medication therapy promotes the idea that
2001; Lisby, Nielson & Mainz 2005). A medica- adverse events are unavoidable. Such events
tion error is any potentially avoidable event were an expected price to pay ‘for the ines-
which may involve inappropriate use of medi- timable benefits’ of modern medication therapy
cations (such as carelessness or negligence), (Barr 1955: 1453). More recently, Hyman and
causing actual or potential harm to a patient Silver (2005: 56) suggest that the high rate
(National Coordinating Council for Medication of error in health care is ‘predictable’ and in-
Error Reporting and Prevention [NCC MERP] evitable given human involvement. Kalra (2004:
2007; Meadows 2003). It can occur as a failure 1043) reiterates the more commonly accepted
to accurately complete an intended action relat- understanding that a limited amount of error is
ing to preparation or administration of a med- unavoidable in any task, and that ‘human fallibil-
ication, or a complete omission of a necessary ity’ in health care should be accepted. Regard-
action. A medication error has four distinctive less of precautions taken, all diagnostic tests,
characteristics: it follows a correctable problem procedures and therapies pose considerable risk
in medication therapy; given the situation, to the patient. Human and technological factors
the error was relatively foreseeable; the cause contributing to error cannot be entirely elimi-
of the error was identifiable; and the cause of nated (Leape 1995b), therefore the view held
the error was controllable without sacrificing by Barr still holds limited credibility today. It is

Volume 31, Issue 2, February 2009 CN 177


CN Jennifer Evans

hoped that the rigidity of this view is rapidly hospitals were due to omissions of medication,
disappearing, even though the prevalence of and 20 percent were as a result of overdosing a
medication errors remains perceivably high in patient. Administering the wrong medication
clinical practice today. accounted for ten percent of errors made in
hospitals and incorrect labelling was reported
PREVALENCE OF MEDICATION to be responsible for less than five percent
ERRORS IN AUSTRALIA (Hodgkinson 2006).
Given the time-critical, delicate and variable In terms of patient safety, the NCC MERP
nature of health care, all health professionals (2002) stated that there is no acceptable occur-
must understand that every patient provides an rence rate of medication errors. The rate of
opportunity for a serious mistake to be made error can be influenced by many factors which
(Wolf et al. 2000). In the clinical environment can increase the likelihood of an error occurring
in Australia, the prevalence of medication errors in specific situations.
is of serious concern (Joanna Briggs Institute
2006).The importance of the statistics outlined RISK FACTORS LEADING TO
below is highlighted by Fogarty and McKeon MEDICATION ERRORS
(2006) who identify adverse events due to med- Mayo and Duncan (2004) surveyed 983 reg-
ication errors as a leading cause of unintentional istered nurses working in acute care hospitals
patient harm within an acute care environment. to determine their perception of medication
The literature shows a reasonably wide range errors.They reported that illegible hand writing
of recorded rates of adverse drug events, rang- of prescriptions, distraction and fatigue were
ing from one to four percent of hospital admis- the highest contributing factors to medication
sions. Specifically, clinical indicators show a one errors. A British study undertaken by Fry and
percent chance of adverse drug event occur- Darcy (2007) identified the most common con-
ring, whereas the medical record reviews have tributors to error as: unclear prescriptions,
shown two to four percent of admissions are high workload, and a busy schedule with many
associated with an adverse medication event pressures. Hand and Barber (2000: 558) identi-
(Runciman et al. 2003). fied ‘personal’, (such as a high level of stress),
In 1995, The Quality in Australian Health ‘contextual’ (such as a noisy ward with many
Care Study was conducted and it remains the patients) and ‘knowledge base’ as the three im-
largest nationally representative study to date portant categories of human error which con-
(ACSQH 2004). Using the data contained in the tributed to medication errors.
study, it can be calculated that approximately As similarly defined by many, human error
two percent of patients will experience a med- involves the failure of intended actions to elicit
ication error, which is of similar magnitude to a desired response, causing deviation from what
the data presented above, from Runciman et al. is right or true (Reason 1997; Hansen 2006).
(2003). Kleinpell (2001) suggests that many of the fac-
Errors can occur at any step in the medica- tors leading to medication errors are human
tion process (from prescribing to administra- related, such as inexperienced or temporary
tion), and an important aspect to consider when staff, caused by a knowledge deficit or inac-
examining the prevalence of medication errors curate documentation. Distractions and other
is the type of error, or at which phase the error impeding factors such as fatigue, stress and not
actually occurred. Data from the Australian focusing on the task can also have very detri-
Incident Monitoring System shows that over a mental effects on the patients’ well being and
quarter of medication incidents occurring in are known to contribute significantly to human

178 CN Volume 31, Issue 2, February 2009


Student corner: Strategies for reducing medication errors in Australian hospitals CN
error in general (Rassin, Kanti & Silner 2005; atric patients often require an increased level of
Woods 2001). vigilance in order to avoid potential medication
While human error is very important to errors (Hughes & Ortiz 2005; McIntyre & Courey
examine, it is equally important to investigate 2007). Paediatric patients have an increased sen-
the context in which the error occurred, that is, sitivity to toxicity levels and thus most dosages
the environment and the specific situation. For are calculated by weight, in significantly smaller
example, although medication errors can occur volumes than adults, increasing the complexity
with any medication, there are a select few that of the calculation. Older adults are at increased
are commonly cited to be involved in medi- risk in part because the number of medications
cation errors (Hughes & Ortiz 2005; Runciman taken increases with age, often due to chronic
et al. 2003). These drug classes include non- illness. Interpreting complex prescriptions for a
steroidal anti-inflammatories, anticoagulants patient on multiple medications can lead to mis-
and opiods. The pharmacokinetic properties of interpretation (Benner et al. 2002). Regardless
many medications may cause them to have a of whether the individual experiencing the
narrow range at which they are clinically benefi- medication error is in the ‘high-risk’ population
cial.This reduced range increases the risk of an or not, the result is just as unexpected and dev-
error, as the therapeutic levels can be difficult to astating to all concerned.
monitor and maintain. A rise in the number of medications available
Another contextual factor which may influ- has seen parallel increases in the level and
ence the safety of medication administration is volume of medication knowledge expected of
characteristics of the medications. In 1961 a registered nurses. As nurses are ultimately
mere 656 medications were available to physi- responsible for any medication they administer,
cians, and in 1995 there was documented to be it is pertinent that their knowledge base is suffi-
over 8000 (Leape 1995a). Today the number is cient, encompassing action, side effects and nor-
probably even higher. Many of these medica- mal dosage. Education and competency are of
tions have similar sounding or looking names. great importance in nursing, especially with
For example Meadows (2003) reports that a relation to medication administration. Nurses
patient received 260 mg of Taxol, instead of the involved in medication administration must
prescribed 260 mg of Taxotere. In this situation ensure that their knowledge of current medica-
both medications are used for chemotherapy, tions is sufficient and awareness of appropriate
but there are many other examples of medi- legislations is maintained (Nurses Board of Vic-
cations that sound alike which are unrelated, toria [NBV] 2007). In its position statement on
such as Serzone (Nefazodone – used to treat the quality use of medicines, the Royal College
depression), and Seroquel (Quetiapine – used of Nursing ([RCN] 1999) states that the admin-
for schizophrenia). Although the continual med- istration of medications is a procedure involving
ication advancements have produced ‘incal- physiological invasion and may result in unwant-
culable benefits’ (Barr 1955: 1453), they also ed and unintended outcomes to the patient.
appear to be contributing to the risk of a med- Therefore it is imperative that the registered
ication error occurring (Tang et al. 2007). nurse possess an extensive understanding of
Just as certain environments increase the risk clinical pharmacology, including knowledge of
of an error occurring, certain patients are con- the mechanical principles of medications and
sidered to be at a higher risk of experiencing a the ability to contextualise specific therapies in
medication error than the general population. given situations, enabling appropriate clinical
Those requiring multiple forms of pharmaco- decisions to be made (Manias & Bullock 2002).
logical therapies, elderly, critically ill and paedi- As well as an objective knowledge of medi-

Volume 31, Issue 2, February 2009 CN 179


CN Jennifer Evans

cations being administered, nurses are also 2001). This punitive environment can result in
required to comprehend the application of the adverse outcomes for the nurse, and indeed the
medication administration procedure. Mathe- patient, as damaged confidence can often result
matical ability is an essential skill for many in changes to clinical practise and competence.
aspects of a nursing career, yet a number of More importantly, it fails to address the under-
studies have identified insufficient levels of lying cause of the error such as the work condi-
accuracy (Polifroni, McNulty & Alllchin 2003; tions which may have contributed.
Bruce & Wong 2001). Performing a medication
calculation requires both arithmetic skills and ADVERSE EVENTS RELATED TO
conceptual skills, including being able to con- MEDICATION ERRORS
textualise the calculation with relevance to the Adverse drug events have been estimated to
patient, medication or clinical scenario (Rainboth cost the Australian public $350 million annually
& DeMasi 2006; Bliss-Holtz 1994).This can be a (Hodgkinson 2006). It has been calculated that
time-consuming, difficult, and anxiety provoking adverse drug events consume approximately
task for nursing students and registered nurses one percent of the total sum spent on health
(Pozehl 1996; Bayne & Bindler 1988). care nation wide (Runciman et al. 2003). Along-
Over the past decade, the health sector has side this, each year in Australia, it is estimated
seen many technological advances, resulting in that general practitioners manage up to 400,000
changes to nursing practice. Although the skill adverse drug events, many of which could
is far from obsolete, there has been a decrease be related to medication errors (Joanna Briggs
in the frequency of medication calculations Institute 2006). Many medication errors can
required of a nurse. The increased reliance on end in tragedy for the patient and family, and
technology has resulted in less demand for even the health professionals and associated
nursing staff to execute medication calculations. agency (Wolf et al. 2000).
This reduced clinical exposure could potentially In 1995, the Quality in Australian Health
lead to a loss of proficiency (Rainboth & DeMasi Care Study reviewed medical records of over
2006; Bindler & Bayne 1991). In 2005 a report 14,000 patients in hospitals across Australia.
published in Finland indicated that nurses were More than half of all occurring medication
aware of their own substandard medication cal- errors were considered preventable. In 77.1
culation abilities (Grandell-Niemi et al.). Prior percent of cases, the resultant disability had
research demonstrating the ability of nurses to resolved within a year, and 13.7 percent of cases
accurately predict their own calculation skills resulted in a long term disability. Medication
supports this assertion (Bayne & Bindler). This errors can sometimes cause fatality, reported as
lack of discrepancy between perceived and actu- occurring in nearly five percent of cases (Wil-
al ability has been apparent for nearly 15 years, son et al 1995).
with potentially incompetent nurses practising Depending on the clinical situation, medica-
medication calculations on a daily basis. tion errors can have a broad range of effects,
Although human error is accountable for from going unnoticed to causing death. For
some medication errors, it is believed that this example, a patient with an Aspirin allergy was
is only a small percentage (Henneman & Gawl- administered Indocin and developed a non-fatal
inski 2004). Unfortunately, because medication respiratory arrest. This event may have been
errors attributable to human fallibility are some- preventable if allergies and contraindicated con-
what easier to recognise, misplaced emphasis ditions were checked first (Hartigan-Go 2006).
contributes to a culture of blame within health- Serumbus,Wolf, and Yongblood (2001) report-
care organisations (Institute of Medicine [IOM] ed a paediatric patient who received an injec-

180 CN Volume 31, Issue 2, February 2009


Student corner: Strategies for reducing medication errors in Australian hospitals CN
tion of a miscalculated dose of the oral form of NURSING STRATEGIES TO
Digitalis and subsequently died. Furthermore, REDUCE THE OCCURRENCE
an older patient with rheumatoid arthritis was OF MEDICATION ERRORS
prescribed a 10 mg weekly dose of Methotrex- Hospitals and health care facilities are continual-
ate, but died as a result of receiving a 10 mg ly working towards reducing medication errors
daily dose (Meadows 2003). through technology, monitoring and education
Medication errors not only have direct ef- (Meadows 2003). As registered nurses are the
fects on the patient and their family, but can also professionals who administer the medication,
carry significant ramifications for healthcare and often deemed the final ‘line of defence’ in
professionals, particularly nurses. In all patient medication administration, there are many nurs-
duties, registered nurses are striving to improve ing strategies which can be implemented to
or maintain patient welfare and avoid harm, avoid potential medication errors (Rainboth &
therefore when a mistake is made it can have a DeMasi 2006: 347).
drastic effect on the individual. They can lose Double checking has long been a strategy
confidence and self esteem, feel guilty, ashamed used to minimise medication errors (Anderson
and embarrassed, as the error is often attributed & Webster 2001). Double checking with anoth-
to ‘poor professional practise’ (Wolf et al. 2000: er registered nurse is essential when preparing
278). Fear and lack of clinical confidence instils and administering a medication; however it does
a sense of mistrust and self-doubt, which not not eliminate the need for other safety proce-
only affects their practise, but also deeply affects dures.The Medicines Governance Project (2004)
their self-perception. puts forward arguments as to why double
The experience of a medication error is often checking may not be considered a safe tech-
reported as being a ‘deeply traumatic’ experi- nique. It suggests that the first person to review
ence in both personal and professional contexts the medication order may rely heavily on the
(Schelbred & Nord 2007: 319). Nurses worry second person, rather than completing an accu-
about the consequences the error may have for rate and safe check themselves, creating a false
the patient’s life, and for themselves in terms of sense of security. Double checking a medication
losing trust and support from colleagues or fac- order can also cause a ‘confirmation bias’ where-
ing professional retributions such as lawsuits, by the second individual has the tendency to
imprisonment and loss of authority or job. The interpret the information as confirming prior
concern caused by these potential outcomes has beliefs. Double checking relies very much on
been reported to contribute to the development human effort, thus the risk for error is high. In
of post traumatic stress disorder and depressive the context of medication administration, it is
symptoms. important that the double checking does not
According to Wolf et al. (2000), healthcare become an autonomous process and therefore
professionals have a social expectation to be worthless.
near perfect, and medication administration Another traditional method of ensuring
remains a traditional nursing task with high patient safety is the ‘five rights principle’. This
responsibility. The reduction of medication involves five essential checks before administer-
errors is a very important issue in a nursing ing a medication – the right medication, dose,
context as nurses are most often the ones who patient, route and time (Crisp & Taylor 2006).
perform the final step in medication process. In The importance of this principle is demonstrat-
Australia and internationally, there has been a ed by Meadows (2003), who reported the death
recent intense effort to control medication of a patient as a result of a massive haemorrhage
errors (Fogarty & McKeon 2006). after receiving another patient’s prescription for

Volume 31, Issue 2, February 2009 CN 181


CN Jennifer Evans

the anticoagulant, Warfarin. This might have sionals to be near perfect appears to have creat-
been prevented if the five rights were vigilantly ed an atmosphere in which mistakes are per-
followed. Much research has been conducted in ceived as intolerable and unacceptable, resulting
this area and it mostly shows that checking these in a degree of dishonesty. Given the potential
five rights helps to ensure safe and effective ad- significance of retribution, (ranging from loss of
ministration of a medication (Wolf et al. 2000). job and self-confidence, to an increased level of
Conflicting results have also been obtained, vigilance when conducting future medication
showing that errors still occur when nurses administrations), many professionals choose to
adhere to the five rights (Smetzer 2000). As in conceal the error (Serumbus et al. 2001). The
most clinical scenarios, there is room for human lack of reporting of errors is a key issue within
error and many human factors such as poor the health care system that needs to be addressed.
handwriting or lack of experience, can con- Wolf et al (2000) suggest that health care
tribute to an inaccurate verification of a right. workers need a better understanding of the
Healthcare facilities that do not employ the use personal impact a medication error can have.
of identification wrist bands (such as aged care Appreciating the anxiety and guilt associated
hostels) can have problems with accurate verifi- with the reporting of a medication error would
cation of identity as verbally questioning the enable them to develop appropriate support in
individual could be tainted by poor hearing or a personal and clinical context. This increased
confusion. Therefore, the five rights on their awareness would also need to incorporate a
own are not enough to prevent high rates of change in perspective, viewing medication errors
medication error. as indicators for continuous quality improve-
Some literature now refers to the sixth right ment, rather than an individual’s failure. In
of medication administration. Wilson and Di- order to do this, medication errors need to
Vito-Thomas (2004), propose the sixth right: be dealt with in a constructive manner. This
right response. This sixth right is intended to includes exploring underlying causes, further
focus on the evaluation of the effectiveness of education or training if required, and support
the medication, and reiterates the importance or professional help to optimise coping mecha-
of taking responsibility for the administration of nisms (Schelbred & Nord 2007).
medications. In clinical scenarios involving pain While the importance of a comprehensive
control, anticoagulant and antiarrhythmic thera- incident reporting scheme is well recognised in
pies, the importance of assessing patient res- the nursing community, many reporting schemes
ponse is evident.This proposed sixth right is not that have been implemented do not elicit very
applicable in all administration situations; how- high levels of response, thus rendering them
ever, it is important that the medication process inadequate (Cullen et al. 1995). If all medica-
does not end at administration. tion errors and potential medication errors are
Many medication errors are not reported reported, the system has the ability to identify
and thus are undetected, so only a minority of and correct problems, sometimes before they
causes can be identified (Anderson & Webster occur (Anderson & Webster 2001). It is also
2001).The reason many nurses and other health essential that near-misses are reported, as near
professionals do not report some medication misses occur more frequently than actual ad-
errors or near errors, is fear of professional and verse events. The NCC MERP (2002) suggest
personal retributions, which could lead to a the following three factors which can affect the
damaged career, reputation or confidence (Wolf reporting of a medication error: a non-punitive
et al. 2000). culture in the health organisation can result in
The social pressure for health care profes- increased reporting, the varied definitions

182 CN Volume 31, Issue 2, February 2009


Student corner: Strategies for reducing medication errors in Australian hospitals CN
among health care organisations can lead to dif- written medication charts, providing intelligent
ferences in classification; and the type of report- support to administration decisions (ACSQH
ing and detection system can alter the number 2004). In its national consensus statement on
of reports. Anderson and Webster believe that lifelong learning, the Australian Nursing Federa-
the reporting system will only reach maximal tion (2005) recommended that information
effectiveness if the levels of reporting are very technology systems be incorporated into nurs-
high. In order to achieve these levels, the error ing education.There are other new-technology
reporting system needs to be run on an anony- techniques such as barcode scanning equipment
mous basis to avoid the blame culture persistent for medications and identification bands (Wolf
in today’s society (Malpass et al. 1999). et al. 2000). Saginur et al. (2008) surveyed
Blame and punishment for error is not con- pharmacy directors of 100 Canadian acute care
ducive to learning and can actually condition hospitals and at least 90 percent of respondents
people to avoid recognising or reporting errors. felt that the use of bar-coding technologies
Openness and a non-punitive approach appear should increase. Although not specifically nurs-
to assist nurses in regaining their confidence fol- ing related, another strategy is the Comput-
lowing a medication error, whereas facilities in erised Physician Order Entry (CPOE), which
which individuals are targeted and punished involves typing orders for medications directly
may result in worsening of emotional response into a computer system. It alerts staff to incom-
and unreported errors in the future (Schelbred patible medications, doses or patient conditions,
& Nord 2007). Therefore punitive reporting as well as eliminating errors made through
systems for medication errors are unlikely to interpretation of written and verbal orders. In a
effectively address safety issues (Henneman & study conducted by Bobb et al. (2004), it was
Gawlinski 2004).The reporting scheme should estimated that 65 percent of prescribing errors
take a systems perspective because the source of were likely preventable with a basic CPOE sys-
an accident is most often a confluence of multi- tem. This finding was supported by research
ple system factors, rather than an individual conducted in 1998 by Bates et al., who iden-
component (Dekker 2005; Kalra 2004). tified a significant reduction in the rate of
Blaming an individual leads to self defensive medication errors with the use of CPOE. In
behaviour and the obscuring of reported in- contrast, Koppel (2005) highlighted several
formation as a self-protection mechanism, thus types of errors that were more likely to occur
clarifying the need for an anonymous reporting with a CPOE system, including dose errors,
system. Natural psychological processes can which were said to be almost twice as likely to
give rise to the tendency for health profes- occur. Shulman et al. (2005) provide an exam-
sionals to attribute all error to human factors ple of how in a particular CPOE system, a drop
(Billings & Woods 2001). Hindsight bias allows down dosage menu contributed to a prescription
fellow practitioners to make causal judgements, of 7 mg/kg of diamorphine instead of 7 mg.
involving oversimplifying contextual factors, With the continual expansion of medication
leading to human attribution. Not being able information, a reliable, accessible and compre-
to identify a direct cause for an error causes hensive source of information is an invaluable
human distress due to the implied lack of con- tool in nursing (George & Davidson 2005). Per-
trol, and blaming an individual feeds the illusory sonal Digital Assistants (PDAs) are small elec-
belief of maintaining control over ‘risky tech- tronic devices which store enormous volumes
nologies’ (Dekker 2005: 199). of regularly updated information.These pocket
It is anticipated that high acuity electronic sized tools aid in obtaining referenced material
recording devices will eventually replace hand quickly and easily, providing informational sup-

Volume 31, Issue 2, February 2009 CN 183


CN Jennifer Evans

port for clinical decisions (Huffstutler,Wyatt & has now been implemented, bringing with it a
Wright 2002). As demonstrated by Greenfield form of safer communication, with a better
(2007), providing immediate access to health understanding of the prescribing process and
information and data at the bedside increases strategies to minimise patient harm (ACSQH
the accuracy, speed and safety of nursing care, 2004; 2005).
decreasing the incidence of medication errors. A strategy that would involve many dis-
The potential of PDA use to improve medica- ciplines within healthcare is the avoidance of
tion safety depends on the sufficiency of the unsafe abbreviations (Abushaiqa et al. 2007).
information available. To be considered suffi- Abbreviations that would be deemed unsafe are
cient, the source must contain specific, accurate those which provide the opportunity for error
and detailed information, able to meet the to occur through misinterpretation of medica-
needs of each clinical decision involved in the tion name, dosage or units. Unsafe abbreviations
process of medication use. One recommended are not only misunderstood, but can also appear
change to further enhance medication safety to mean something completely unintended
was the inclusion of specific product details when combined with other surrounding words,
(such as colour, markings and size) in PDA data numerals or symbols (New South Wales Thera-
sources (Galt et al. 2005). peutic Advisory Group [NSW TAG] 2007).
In 2003, the IOM published a report which Meadows (2003) for example, described a patient
identified the use of information technology as who died as a result of an order for 20 units of
one of five core areas in which students and insulin being abbreviated to ‘20U’. The U was
working health professionals must develop and mistaken as a zero and subsequently the patient
maintain proficiency. All clinicians need to was injected with 200 units. In order to pro-
understand the limitations of technology and mote adequate patient safety, universal and
continue to exercise vigilance in all patient unambiguous symbols and abbreviations need to
duties.Whilst computerised technology has the be used consistently (NSW TAG 2006).
potential to improve the level of patient safety, The ACSQH (2002) suggest the risk of error
it is also possible that new types of errors will in medication administration from a ward stock
arise. Clinicians are more likely to ignore exces- supply is 15–20 percent, a much higher inci-
sive warnings produced by PDAs or other such dence compared to when individual patient
technology, which may lead to an adverse event stocks are used (five to eight percent).This evi-
occurring (Gaddis, Holt & Woods 2002). The dence suggests that it is a safer option to have
reliance on computer systems may also lead to a pharmacy staff measure and dispense individual
reduction in human vigilance, resulting in nurs- patient doses. This would also reduce nursing
es being less aware of medication characteristics workload, as medication preparation and ad-
and possibly making an error they would not ministration have been reported to consume
have made otherwise (NHMRC 2006). nearly 40 percent of nursing shift time (Armi-
Health ministers across Australia supported tage & Knapman 2003). However, giving the
the idea of a national drug chart across all Aus- extra responsibility of measuring individual
tralian hospitals as a way to reduce medication doses to pharmacists may act as transference of
errors related to documentation (Leach 2006). the problem, rather than a long term solution.
A study conducted by Leach in 2006 showed a Mathematical proficiency has been identified
marked reduction in documentation errors (of as an area requiring improvement at the tertiary
allergies, dose and frequency) and reduced pre- level (Rainboth & DeMasi 2006), which in-
scription errors when 31 hospitals used a stan- dicates the need for better mathematical or
dardised drug chart. This national drug chart numeracy training prior to commencing an

184 CN Volume 31, Issue 2, February 2009


Student corner: Strategies for reducing medication errors in Australian hospitals CN
undergraduate nursing program. Mathematical in pharmacology was also noted. Improved
education should be a prerequisite for any under- pharmacological education has the potential to
graduate nursing course (Cartwright 1996).The increase confidence and proficiency in medica-
current lack of formal numeracy demands for tion administration for nurses. Presently there
entry into an undergraduate nursing course in are no national competency guidelines which
Australia poses an interesting contrast to that explicitly identify adequate amount and depth
of undergraduate medicine courses. Students of pharmacological knowledge for nursing prac-
applying to study medicine would not even be tice (Bullock & Manias 2002); therefore the
considered for the course without sufficient development of such competencies is indicated
mathematical competency, why nursing courses in order to ascertain appropriate curricular con-
lack such requirements is mystifying. A study tent at an undergraduate level.
conducted in Sweden supports the need for
such a prerequisite, showing poorer scores ob- SUMMARY
tained in calculation exercises from undergrad- This paper has reviewed the literature on med-
uate nursing students without mathematical ication errors in acute care settings with a focus
backgrounds (Kapbord 1995). on Australian prevalence, risk factors, conse-
Even though the frequency of medication cal- quences and specific nursing strategies to pre-
culations exists in an inverse relationship with vent errors from occurring. Patient safety is a
advancing technology, they are still a vital con- key consideration in healthcare, which reflects
tributor to the occurrence of medication errors. the nature of a medication error, which can be
In order to rectify the preventable adverse events controlled without sacrificing the essential ben-
occurring as a result of calculation errors, efits of therapy (Helper & Segal 2003).
researchers have identified the need to address Labelled as the leading cause of unintentional
the issue at a tertiary level (Rainboth & DeMasi patient harm, medication errors are a serious
2006). Many tertiary institutions are developing issue in nursing which needs to be addressed
modules to increase the calculation proficiency (Fogarty & McKeon 2006). Although the likeli-
of their graduate nurses (Elliott & Joyce 2005). hood of an individual error occurring is seem-
Educating students from the outset of their ingly low, the serious nature of the associated
nursing career may help to instil a satisfactory consequences is enough to justify immediate
level of skill, potentially reducing the risk of an action. A medication error can produce devas-
error being made as a registered nurse. It is also tating results, threatening patients’ lives and
essential that calculation competency is main- jeopardising nurses’ confidence, job security
tained post graduation. According to O’Shea and job satisfaction.
(1999), many healthcare facilities have imple- Registered nurses have a high level of res-
mented measures such as periodically testing ponsibility in all areas of patient care, especially
calculation ability of nurses in the work place. administration of medications. The wide range
Weeks, Lyne and Torrance (2000) state that it is of pharmaceutical products available and dra-
a critical skill and needs to be reinforced in both matically changing technology adds to the
pre-registration educational and clinical domains. already complex situation (Anderson & Webster
King (2004) interviewed ten nurses emp- 2001). This increasing complexity of the med-
loyed in an emergency care facility about the ication administration environment places in-
educational needs for pharmacological knowl- creased pressure on nurses’ busy schedule and
edge in nursing. Her results indicated that there provides greater opportunity for error to occur.
was limited pharmacological knowledge among As nurses have the final contact with the
participants; recognition of inadequate teaching medication before it is administered to the

Volume 31, Issue 2, February 2009 CN 185


CN Jennifer Evans

patient, it is important that all errors are ade- Healthcare [ACSQH] (2002) Second National
quately recognised and specific nursing strate- Report on Patient Safety: Improving Medication
gies are implemented to reduce medication Safety, Australian Commission on Safety and
error rates. Although nurses bear a lot of res- Quality in Healthcare, Canberra.
ponsibility and are frequently targeted as the Australian Commission on Safety and Quality in
primary cause of the error, it must be realised Healthcare [ACSQH] (2004) Charting the
that in the majority of cases, the error can be Safety and Quality of Healthcare in Australia,
attributed to ‘the systems, rather than the indi- ACSQH, accessed at http://www.safetyand
vidual’ (Beyers 2000: 56; Anderson & Webster quality. org/internet/safety/publishing.nsf
2001). /Content/charting on August 29 2007.
Many strategies have already been imple- Australian Commission on Safety and Quality in
mented in Australia and many are nursing tar- Healthcare [ACSQH] (2005) National
geted. For example adequate incident reporting Inpatient Medication Chart (NIMC) –Version E,
schemes (Anderson & Webster 2001), enhanced ACSQH, accessed at http://www.health.gov
mathematical preparation (Rainboth & DeMasi .au/internet/safety/publishing.nsf/Content
2006) and a nation-wide common drug chart /80A0EF37F281A8D7CA25718F000CCC2
(Leach 2006). The strategies that have been F/$File/chverse.pdf on November 20, 2008.
implemented targeting the reduction medica- Australian Nursing Federation [ANF] (2005)
tion error rate have been quite successful, and it National Consensus Statement on Nurses and Life-
is envisaged that they will continue to do so. long Learning, Canberra, Australia.
However, due to the nature of nursing and med- Barr D (1955) Hazards of modern diagnosis and
ical care – both human and technological, the therapy – the price we pay, JAMA 159(15):
risk of error can theoretically never reach zero 1452–1456.
(Leape 1995b). Bates D, Leape L, Cullen D, Laird N, Petersen L,
Teich J, Burdick E, Hickey M, Kleefield S, Shea
Acknowledgement B,Vander M and Seger D (1998) Effect of
Thank you to Malcolm Elliott and Jane Walker computerized physician order entry and a team
for their continual support and assistance with intervention on prevention of serious medica-
editing. tion errors, JAMA 280(15): 1311–1316.
Bayne T and Bindler R (1988) Medication calcu-
References lation skills of registered nurses, The Journal
Abushaiqa M, Zaran F, Bach D, Smolarek R, and of Continuing Education in Nursing 19(6):
Farber M (2007) Educational interventions 258–262.
to reduce use of unsafe abbreviations, Ameri- Benner P, Sheets V, Uris P, Malloch K, Schwed K
can Journal of Health Systems Pharmacy 64(11): and Jamison D (2002) Individual, practice
1170–1173. and system causes of errors in nursing: a
Anderson D and Webster C (2001) A systems taxonomy, Journal of Nursing Administration
approach to the reduction of medication 32(10): 509–523.
error on the hospital ward, Journal of Advanced Beyers M (2000) About a four-point plan to
Nursing 35(1): 34–41. reduce medication errors, Nursing Management
Armitage G and Knapman H (2003) Adverse 31(2): 56.
events in drug administration: a literature Billings C and Woods D (2001) Human error in
review, Journal of Nursing Management 11(2): perspective: the patient safety movement,
130–140. Postgraduate Medicine Online 109(1).
Australian Commission on Safety and Quality in Bindler R and Bayne T (1991) Medication

186 CN Volume 31, Issue 2, February 2009


Student corner: Strategies for reducing medication errors in Australian hospitals CN
calculation ability of registered nurses, to incidents in medicine administration part
Journal of Nursing Scholarship 23(4): 221–224. 1, British Journal of Nursing 16(9): 556–559.
Bliss-Holtz J (1994) Discriminating types of Gaddis G, Holt T and Woods M (2002) Drug
medication calculation errors in nursing interactions in at risk emergency department
practice, Nursing Research 43(6): 373–375. patients, Academy of Emergency Medicine 9:
Bobb A, Gleason K, Husch M, Feinglass J, 1162–1167.
Yarnold P and Noiskin G (2004) The epi- Galt K, Rule A, Houghton B,Young D and
demiology of prescribing errors: the poten- Remington G (2005) Personal digital assis-
tial impact of computerised prescriber order tant-based drug information sources: poten-
entry, Archives of Internal Medicine 164(7): tial to improve medication safety, Journal of
785–792. the Medical Library Association 93(2): 229–236.
Bruce J and Wong I (2001) Parenteral medica- George L and Davidson C (2005) PDA use in
tion administration errors by nursing staff on nursing education: prepared for today, poised
an acute medical admissions ward during day for tomorrow, Online Journal of Nursing In-
duty, Drug Safety 24(11): 855–862. formatics 9(2), accessed at http://eaa-knowl
Bullock S and Manias E (2002) The Educational edge.com/ojni/ni/9_2/george.htm on 20
preparation of undergraduate nursing stu- November 2008.
dents in pharmacology: a survey of lecturers’ Grandell-Niemi H, Hupli M, Leinno-Kipli H
perceptions and experiences, Journal of Ad- and Puukka P (2005) Finnish nurses’ and
vanced Nursing 40(1): 7–16. nursing students pharmacological skills, Issues
Cartwright M (1996) Numeracy needs of the in Clinical Nursing 14: 685–694.
beginning registered nurse, Nurse Education Greenfield S (2007) Medication error reduction
Today 16(2): 137–143. and the use of PDA technology, Journal of
Crisp J and Taylor C (2006) Potter and Perry’s Nursing Education 46(3): 127–131.
Fundamentals of Nursing, 2nd edn, Elsevier, Hand K and Barber N (2000) Nurses’ attitude
Marrickville NSW. and beliefs about medication errors in a UK
Cullen D, Bates D, Small S, Cooper J, Nemeskal hospital, International Journal of Pharmacy
A and Leape L (1995) The incident reporting Practice 8(2): 128–134.
system does not detect adverse drug events: a Hansen F (2006) Human error:A concept analy-
problem for quality improvement, Joint Com- sis, Journal of Air Transportation 11(3): 61–77.
mission Journal on Quality Improvement 21(10): Hartigan-Go K (2006) Medication Errors,
541–548. International Journal of Risk & Safety in Medicine
Dekker S (2005) Ten Questions About Human Error: 18(3): 181–186.
A NewView of Human Factors and System Safety, Hawkey C and Langman M (2003) Non-
Lawrence Erlbaum Associates: Mahwah, NJ. steroidal anti-inflammatory drugs: overall
Elliott M and Joyce J (2005) Mapping drug cal- risks and management. Complementary roles
culation skills in an undergraduate nursing for COX-2 inhibitors and proton pump
curriculum, Nursing Education in Practise 5: inhibitors, Gut: Journal of the British Society of
225–229. Gastroenterology 52: 600–608.
Fogarty G and McKeon C (2006) Patient safety Helper C and Segal R (2003) Preventing Medica-
during medication administration:The influ- tion Errors and Improving Drug Therapy Outcomes:
ence of organisational and individual vari- A Management Systems Approach, CRC Press,
ables on unsafe work practices and medica- Boca Raton, FL.
tion errors, Ergonomics 49(5–6): 444–456. Henneman E and Gawlinski A (2004) A ‘near
Fry M and Dacey C (2007) Factors contributing miss’ model for describing the nurses role in

Volume 31, Issue 2, February 2009 CN 187


CN Jennifer Evans

the recovery of medical errors, Journal of chart implementation, Journal of Pharmacology


Professional Nursing 20(3): 196–201. Practise and Research 36(1): 6–27.
Hodgkinson B (2006) Strategies to reduce medi- Leape L (1995a) Out of darkness: hospitals
cation errors with reference to older adults, begin to take mistakes seriously, Health
International Journal of Evidence-Based Healthcare Systems Review 28: 24–27.
4(1): 2–41. Leape L, Bates D, Cullen D, Cooper J, Demon-
Huffstutler S,Wyatt T and Wright C (2002) The aco H, Gallivan T, Hallisey R, Ives J, Laird N,
use of handheld technology in nursing educa- Laffel G et al. (1995b) Systems analysis of
tion, Nurse Educator 27(2): 271–275. adverse drug events, JAMA 274(1): 35–43.
Hughes R and Ortiz E (2005) Medication errors: Lisby M, Nielsen L and Mainz J (2005) Errors
why they happen and how they can be preven- in the medication process: frequency, type
ted, American Journal of Nursing 105(3): 14–24. and potential, International Journal for Quality
Hyman D and Silver C (2005) Speak not of in Health Care 17(1): 15–22.
error, Regulation 28(1): 52–58. Malpass A, Helps S, Sexton E, Maiale D and
Institute of Medicine [IOM] (2001) Crossing the Runciman W (1999) A classification for
Quality Chasm:A New Health System for the 21st adverse events, Journal of Quality in Clinical
Century. National Academy Press:Washington Practice 19(1): 23–26.
DC. Mayo A and Duncan D (2004) Nurse percep-
Institute of Medicine [IOM] (2003) Health pro- tions of medication errors: what we need to
fessions education: a bridge to quality, National know for patient safety, Journal of Nursing
Academy Press:Washington DC. Care Quality 19(3): 209–217.
Institute of Medicine [IOM] (2006) Preventing McIntyre L and Courey T (2007) Safe medica-
Medication Errors: Quality Chasm Series, Nation- tion administration, Journal of Nursing Care
al Academy Press,Washington DC. Quality 22(1): 40–42.
Joanna Briggs Institute (2006) Strategies to Meadows M (2003) Strategies to reduce medi-
reduce medication errors with reference to cation errors, FDA Consumer 37(3): 20–27.
older adults, Australian Nursing Journal 14(4): Medicines Governance project (2004) Medica-
26–29. tion Safety Today, Northern Ireland Medicines
Kalra J (2004) Medical errors: an introduction Governance Project Newsletter 7: 2.
to concepts, Clinical Biochemistry 37(12): National Health and Medical Research Council
1043–1051. [NHMRC] (2006) Australian Patient Safety
Kapborg I (1995) An evaluation of Swedish Bulletin, NHMRC Newsletter 2006(3).
nurse students’ calculating ability in relation National Coordinating Council for Medication
to their earlier educational background, Error Reporting and Prevention [NCC
Nurse Education Today 15(1):69–74. MERP] (2007) About medication errors, NCC
King R (2004) Nurses’ perceptions of their MERP, accessed at http://www.nccmerp.org
pharmacological educational needs, Journal of /aboutMed Errors.html on 1 January 2008.
Advanced Nursing 45(4): 392–400. National Coordinating Council for Medication
Kleinpell R (2001) Characteristics of medication Error Reporting and Prevention [NCC
errors revealed, Nursing Spectrum 2(2): 39. MERP] (2002) Use of Medication Error Rates to
Koppel R (2005) What do we know about Compare Health Care Organisations is of No Value,
medication errors made via a CPOE system Statement from NCC MERP, accessed at
versus those made via handwritten orders? http://www.nccmerp.org/council/council2
Critical Care 9(5): 427–428. 002-06-11.html on 26 December 2007.
Leach H (2006) National inpatient medication New South Wales Therapeutic Advisory Group

188 CN Volume 31, Issue 2, February 2009


Student corner: Strategies for reducing medication errors in Australian hospitals CN
Inc. [NSW TAG] (2006) Recommendations for safety in Canadian Hospitals, Journal of
Terminology,Abbreviations and Symbols used in Evaluation in Clinical Practice 14(1): 27–35.
the Prescribing and Administration of Medicines, Schelbred A and Nord R (2007) Nurses’ experi-
Safer Medicines Group. ences of drug administration errors, Journal
New Sound Wales Therapeutic Advisory Group of Advanced Nursing 60(3): 317–324.
Inc. [NSW TAG] (2007) Indication for quality Serembus J,Wolf Z and Yongblood N (2001)
use of medicines in Australian hospitals, Safer Consequences of fatal medication errors for
Medicines Group. health care providers: A secondary analysis
Nurses Board of Victoria [NBV] (2007) Code for study, MEDSURG Nursing 10(4): 193–202.
Guidance: Management of the Administration of Shulman R, Singer M, Goldstone J and Belling-
Medications for High Care Residents in an Aged an G (2005) Medication errors: a prospective
Care Service, NBV. cohort study of hand-written and computer-
O’Shea E (1999) Factors contributing to medi- ised physician order entry in the ICU, Critical
cation errors: a literature review, Journal of Care 9(5): R516–R521.
Clinical Nursing 8(5): 496–504.
Smetzer J (2000) The ‘five rights’, AHA News
Polifroni C, McNulty J and Allchin L (2003) 36(41): 8.
Medication errors: more basic than a system
Tang FI, Sheu SJ,Yu S and Wei CH (2007)
issue, Journal of Nursing Education 42(10):
Nurses relate the contributing factors in-
455–458.
volved in medication errors, Journal of
Pozehl B (1996) Mathematical calculation
Clinical Nursing 16(3): 447–457.
ability and mathematical anxiety of bacca-
laureate nursing students, Journal of Nursing Weeks K, Lyne P and Torrance C (2000)
Education 35(1): 37–39. Written drug dosage errors made by stu-
dents: the thread to clinical effectiveness and
Rainboth L and DeMasi C (2006) Nursing
the need for a new approach, Clinical Effec-
students’ mathematical calculation skills,
tiveness in Nursing 4: 20–29.
Nursing Education in Practice 6(6): 347–353.
Rassin M, Kanti T and Silner D (2005) Chron- Wilson D and DiVito-Thomas P (2004) The sixth
ology of medication errors by nurses: accumu- right of medication administration: right
lation of stresses and PTSD symptoms, Issues in response, Nurse Educator 29(4): 131–132.
Mental Health Nursing 26(8): 873–886. Wilson R, Runciman W, Gibberd R, Harrison
Reason J (1997) Managing the risks of organisa- B, Newby L and Hamilton J (1995) The
tional accidents, Ashgate Publishing Limited, Quality in Australian Health Care Study, The
Aldershot, UK. Medical Journal of Australia 163(6).
Royal College of Nursing [RCN] (1999) Position Wolf Z, Serembus J, Smetzer J, Cohen H and
Statement: Registered Nurses and the Quality Use Cohen M (2000) Responses and concerns of
of Medicines, Royal College of Nursing healthcare providers to medication errors,
Australia. Clinical Nurse Specialist 14(6): 278–287.
Runciman W, Roughead E, Semple S and Adams Wolf Z (2007) Pursuing sage medication use
R (2003) Adverse drug events and medica- and the promise of technology, Medsurg
tion errors in Australia, International Journal Nursing 17(2): 92–100.
for Quality in Health Care 15(1): i49–i59. Woods K (2001) The Prevention of Intrathecal
Saginur M, Graham I, Forster A, Boucher M Medication Errors:A Report to the Chief Medical
and Wells G (2008) The uptake of tech- Officer, NHS Health Technology Assessment
nologies designed to influence medication Programme.

Volume 31, Issue 2, February 2009 CN 189


Copyright of Contemporary Nurse: A Journal for the Australian Nursing Profession is the property of eContent
Management Pty. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv
without the copyright holder's express written permission. However, users may print, download, or email
articles for individual use.

You might also like