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DRUG NAME DOSAGE ACTION INDICATION ADVERSE CONTRAINDICATION NURSING

AND ROUTE EFFECTS RESPONSIBILITIES


ROCEPHIN® DOSING: Cephalosporin LOWER Adverse Rocephin is • Patients should be
(ceftriaxone NEONATES: s (sef-a-loe- Reactions: contraindicated in counseled that
RESPIRATORY
SPOR-ins) are
sodium) for Hyperbilirubine TRACT Allergic patients with known antibacterial drugs
used in the
Injection mic neonates, treatment of INFECTIONS reactions, drug allergy to the including Rocephin
especially infections fever, serum cephalosporin class of should only be used
Rocephin is a prematures, caused by
ACUTE sickness-like antibiotics. to treat bacterial
sterile, should not be bacteria. They reaction, renal infections. They do
work by killing BACTERIAL
semisynthetic, treated with dysfunction, Neonates ( ≤ 28 days) not treat viral
bacteria or OTITIS MEDIA
broad-spectrum Rocephin preventing their toxic infections (eg,
cephalosporin growth. nephropathy, Hyperbilirubinemic common cold). When
antibiotic for SKIN AND SKIN reversible Rocephin is
neonates, especially
intravenous or Pediatric Cephalosporin STRUCTURE hyperactivity, prematures, should not be prescribed to treat a
intramuscular Patients s are used to INFECTIONS hypertonia, treated with Rocephin. In bacterial infection,
treat infections
administration. in many
hepatic vitro studies have shown patients should be
For the different parts
URINARY dysfunction that ceftriaxone can told that although it is
treatment of of the body. TRACT including displace bilirubin from its common to feel better
skin and skin They are INFECTIONS cholestasis, binding to serum early in the course of
structure sometimes aplastic albumin, leading to a therapy, the
given with
infections, the UNCOMPLICAT anemia, possible risk of bilirubin medication should be
other
recommended antibiotics. ED hemorrhage, encephalopathy in these taken exactly as
total daily dose Some GONORRHEA and patients. directed. Skipping
is 50 to 75 cephalosporins superinfection. doses or not
mg/kg given given by Rocephin is completing the full
injection are PELVIC
once a day (or contraindicated in course of therapy
also used to INFLAMMATOR
in equally prevent neonates if they require may (1) decrease the
Y DISEASE
divided doses infections (or are expected to effectiveness of the
twice a day). before, during, require) treatment with immediate treatment
The total daily and after BACTERIAL and (2) increase the
calcium-containing IV
surgery. SEPTICEMIA
dose should not solutions, including likelihood that
bacteria will develop
exceed 2 However, BONE AND continuous calcium- resistance and will
grams. cephalosporins containing infusions not be treatable by
will not work for
JOINT
colds, flu, or INFECTIONS such as parenteral Rocephin or other
Adults other virus nutrition because of the antibacterial drugs in
infections. INTRA- risk of precipitation of the future.
The usual adult ABDOMINAL ceftriaxone-calcium
daily dose is 1 Diarrhea is a common
INFECTIONS
to 2 grams . problem caused by
given once a antibiotics which
MENINGITIS usually ends when the
day (or in
equally divided antibiotic is
doses twice a SURGICAL discontinued.
day) depending PROPHYLAXIS Sometimes after
on the type and starting treatment
severity of with antibiotics,
infection. The patients can develop
total daily dose watery and bloody
should not stools (with or
exceed 4 without stomach
grams. cramps and fever)
even as late as two or
Intramuscular more months after
Administration having taken the last
: Reconstitute dose of the antibiotic.
Rocephin If this occurs, patients
powder with should contact their
the appropriate physician as soon as
diluents possible.

Intravenous
Administration
: Rocephin
should be
administered
intravenously
by infusion
over a period of
30 minutes.
Concentrations
between 10
mg/mL and 40
mg/mL are
recommended;
however, lower
concentrations
may be used if
desired.
Reconstitute
vials with an
appropriate IV
diluent

DRUG DOSAGE AND ACTION INDICATION ADVERSE CONTRAINDIC NURSING


NAME ROUTE EFFECTS ATION RESPONSIBILITIES
Brand Tablets-250, 500 mg- Bactericidal:  Acute infection Headache,  Contraind  Take full
Name: 750mg; Inhibits with dizziness, icated course of drug
Flagyiasisl Capsules-375 mg; synthesis in susceptible ataxia, with therapy; take
Powder for injection- specific insomia,
Generic 500 mg; anaerobes, anaerobic seizures, hypersens the drug with
Name: Injection-500 mg/100 causing cell bacteria. fatigue, itivity to food if GI
Metronidazo ml; death;  Acute incontinence, metronida upset occurs.
le Lotion, cream, gel- antiprotozoal- intestinal dryness, zole.  Do not drink
0.75%; trichomonacid amebiasis anorexia,  Use alcohol.
al.  Amebic liver diarrhea, cautiously  Your urine
Route: abscess nausea. with CNS maybe a
ORAL, IV,  Trichomoniasis diseases, darker color
TOPICAL(METROG (acute and hepatic than usual; this
EL) partners of disease, is expected.
patients with candidiasi  Refrain from
acute infection. s, blood sexual
dyscrasias intercourse
, lactation. during
treatment for
trichomoniasis
, unless
partner wears
a condom.

DRUG NAME DOSAGE ACTION INDICATION ADVERSE CONTRAINDICATION NURSING


AND EFFECTS RESPONSIBILITIES
ROUTE
Brand Name: Tablets- Competitively  Diagnosis and Dizziness,  Contraindicated  Mark
Aldactone 25,50,100 block the maintenance of headache, with allergy to calendars of
mg. effects of primary drowsiness, spironolactone, edema
Generic Name: aldosterone in hyperaldostero fatigue, ataxia, hyperkalemia, renal outpatients as
Spironolactone the renal nism confusion, disease, anuria, reminders of
tubule, causing  Adjunctive cramping aminloride, or alternate-day
loss of sodium therapy in diarrhea, dry triamterence use. or 3-5
and water and edema mouth, thirst,  Use cautiously with day/week
retention of associated with vomiting, pregnancy therapy.
potassium. heart failure, hyperkalemia.  Give daily
nephrotic doses early
syndrome, so that
hepatic increased
cirrhosis when urination
other therapies does not
are inadequate interfere with
or sleep.
inappropriate.  Measure and
 Treatment for record
hypokalemia, regular
or prevention weight to
of hypokalemia monitor
in patients who mobilization
would be at of edema
high risk if fluid.
hypokalemia  Avoid giving
occurred; food rich in
digitalized potassium
patients,
patients with  Arrange for
cardiac regular
arrhythmias evaluation of
 Essential serum
hypertension, electrolytes
usually in and
combination BUN(Blood
with other
drugs. Urea
Nitrogen)

DRUG NAME DOSAGE ACTION INDICATION ADVERSE CONTRAINDICATION NURSING


AND ROUTE EFFECTS RESPONSIBILITIES
Brand name: Powder for Bactericidal: Lower Headache,  Contraindicated  Avoid
Rocephin injection-2g; inhibits respiratory dizziness, with allergy to alcohol while
Injection-1,2g synthesis of infections caused lethargy, cephalosporins or taking this
Generic name: bacteria cell by streptococcus nausea, penicillins. drug and for
Ceftriaxone wall, causing pnemoniae, vomiting, pain,  Use cautiously with 3 days after
cell death. staphylococcus decreased renal failure, because
aureus, WBC count, lactation, severe
Escherichia coli decreased pregnancy reactions
platelets, often occur.
abdominal pain,  You may
flatulence, experience
anorexia. these side
effects:
stomach
upset or
diarrhea
 Report severe
diarrhea,
difficulty
breathing,
unusual
tiredness or
fatigue, pain
at injection
site

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