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Herdiana, Safira Putri. 2018. Uji Beda Penggunaan Salep Povidone Iodine
10% dan Salep Ekstrak Kunyit Terhadap Jumlah Fibroblast
Pada Proses Penyembuhan Luka Sayat Tikus Putih Jantan
(Rattus norvegicus strain wistar). Tugas Akhir, Fakultas
Kedokteran Universitas Muhammadiyah Malang. Pembimbing: (1)
dr. Mochammad Aleq Sander, M Kes., Sp.B., FINACS (2) dr. Gita
Sekar Prihanti MPd. Ked
Metode: True Experimental, Post Test Only Control Group Design. Sampel
dibagi 3 kelompok. Kelompok 1 kontrol positif (transparent dressing),
kelompok 2 (aplikasi salep povidone iodine 10%), kelompok 3 (aplikasi salep
ekstrak kunyit). Hewan uji diberi perlukaan sayatan pada punggung, dengan
ukuran ± 2 cm. Pengambilan sampel jaringan kulit dilakukan setelah 14 hari.
Untuk melihat jumlah fibroblast dilakukan pembuatan preparat dengan
pengecatan Hematoxylin Eosin.
Kata Kunci: Fibroblast, salep ekstrak kunyit, salep povidone iodine 10%.
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ABSTRACT
Methods: True experimental and post-test only group design were used. The
sample were divided into three groups. They were positive control
(transparent dressing), group 2 (povidone iodine 10% ointment), group 3
(turmeric extract ointment). The animals test were given incision in the back
of the vertebrae, with incision size of ± 2 cm. Skin tissue sampling was
performed after 14 day. To see the number of fibroblast done making
preparations with Hematoxylin eosin staining.
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