Bibliografia

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Sulem, P., Gudbjartsson, D.F., Stacey, S.N., Helgason, A., Rafnar, T., Magnusson, K.P., Manolescu,
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40 Liu F, Wollstein A, Hysi PG et al. Digital quantification of human eye color highlights genetic
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18 Jacobs LC, Liu F, Pardo LM et al. IRF4, MC1R, and TYR genes are risk factors for actinic keratosis
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4 Sulem P, Gudbjartsson DF, Stacey SN et al. Genetic determinants of hair, eye and skin
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19 Jacobs LC, Hamer MA, Gunn DA et al. A Genome-Wide Association Study Identifies the Skin
Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots. J Invest Dermatol
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43 Duffy DL, Iles MM, Glass D et al. IRF4 variants have age-specific effects on nevus count and
predispose to melanoma. Am J Hum Genet 2010; 87: 6-16. (a)

44 Gualco G, Weiss LM, Bacchi CE. MUM1/IRF4: A Review. Appl Immunohistochem Mol Morphol
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45 Shah PP, Donahue G, Otte GL et al. Lamin B1 depletion in senescent cells triggers large-scale
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46 Do TN, Ucisik-Akkaya E, Davis CF et al. An intronic polymorphism of IRF4 gene

influences gene transcription in vitro and shows a risk association with childhood acute
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6 Park HY, Kosmadaki M, Yaar M et al. Cellular mechanisms regulating human

melanogenesis. Cell Mol Life Sci 2009; 66: 1493-506.

7 Sturm RA. A golden age of human pigmentation genetics. Trends Genet 2006; 22: 464-8.

8 Praetorius C, Grill C, Stacey SN et al. A Polymorphism in IRF4 Affects Human

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