Date Name of the Classification & Dose, Rouse Mechanism of Contraindication Side Effects Nursing

Ordered Drug Indication & Frequency Action Responsibilities

Generic Name: Classification: The plasma kinetics Hypercalcemia, Hypercalcemia After

1-2-18 Ketoanalogue Used in the of amino acids and disturbed amino may develop. 1. Assess
treatment of their integration in acid metabolism. electrolyte levels
Brand Name: urological problems. metabolic pathways In case of 2. Explain
Ketosterile are well established. hereditary therapeutic value
Indication: It should phenylketonuria, of drug
Prevention and nevertheless be it has to be taken 3. Assess allergy to
therapy of damages noted that, in uremic into account that the drug
due to faulty or patients, the plasma ketoanalogue 4. Caution patient
deficient protein disturbances do not contains of the different side
metabolism in seem to depend on phenylalanine. effects
chronic renal digested amino acid Disturbed amino 5. Assess vital
insufficiency in intake, and that the acid metabolism signs
connection with postabsorptive 6. Proper
limited protein food kinetics seems to be preparation of the
of ≤40 g/day (for distributed very drug
adults). early in the Before
development of the 1. Document
disease. In normal administration of
individuals, there is the drug.
an increase in the 2. Instruct patient
plasma level of to report
ketoanalogues,10 immediately if
min after oral symptoms of
ingestion! These hypercalcemia
levels reach values occurs like muscle
that are weakness,
approximately ' constipation
times higher than 3. Monitor calcium
the initial level! Peak levels.
levels are reached 4. Monitor for signs
within 20-60 min of hypercalcemia
and normal levels and electrolyte
are reached again levels.
after 90 5. Monitor vital
mins.gastrointestinal signs especially
absorption is thus cardiac changes.
very rapid! In the
plasma a
simultaneous
increase in levels of
the ketoanalogue
and the
corresponding
amino acid shows
that transamination
of the
ketoanalogues are
very rapid! Due to
natural pathways of
disposal of a-ketonic
acids in the
organism, it is
probable that
exogenous intakes
are very rapidly
integrated into
metabolic
cycles.Ketoacids
follow the same
catabolic pathways
as the classical
amino acids,No
specific study on
ketoacid excretion
has been performed
to date.