Procedures to Prevent Perinatal

Hepatitis B Virus Transmission at Delivery

Maternal Surface Antigen (HBsAg) Test Results AVAILABLE

Woman presents for delivery

HBsAg HBsAg
Maternal
HBsAg
results

• Place copy of woman’s original HBsAg lab report in: HBV

Yes risk factor No
- Woman’s labor and delivery chart present?
- Infant’s hospital record See perinatal
Retest HBsAg algorithm results for Risk Factors:
• Alert nursery staff that infant needs HepB and HBIG unavailable at birth • ≥ 2 sex partners
vaccine within 12 hours of birth in previous 6 months
• STD
• Administer HepB and HBIG vaccine to infant within HBsAg HBsAg • Injection drug use
12 hours of birth or as soon as possible thereafter Maternal • HBsAg+ partner
HBsAg • Clinical hepatitis
• Alert pediatric provider (if known) results
• Alert public health department perinatal hepatitis B
coordinator • Place copy of woman’s original HBsAg lab report in:
• Report results in Immunization Registry - Woman’s labor and delivery chart
- Infant’s hospital record

Yes Baby No
weighs less than
2000g Baby
Yes No
weighs less than
Administer another Follow recommended 2000g
dose of HepB vaccine HepB vaccination Discharge Instructions:
one month after birth schedule • Provide woman with infant’s
Administer first dose Administer first dose
Note: Birth dose does immunization record
of HepB vaccine at of HepB vaccine
not count toward • Emphasize importance of bringing hospital discharge or before infant leaves
vaccine series record to pediatric provider at one month after birth hospital
each visit
Follow‐up with public health department • Educate woman about importance of
perinatal hepatitis B coordinator completing infant’s vaccine series

Resources available at www.CDC.gov/hepatitis/perinatalHepB