DRUG STUDY

DRUG NAME ACTION INDICATION CONTRAINDICATION ADVERSE EFFECTS DOSAGE NURSING RESPONSIBILITIES

GENERIC NAME: It is similar to Treatment of Hypersensitivity to CNS: headache, IV/500 - Obtain history of hypersensitivity
Piperacillin / that of other moderate to severe penicillins, insomnia, fever mg/q8 to penicillins, cephalosphorins, or
Tazobactam penicillins. appendicitis, cephalosphorins, or other drugs prior to
Interfere with uncomplicated and other drugs. Safety in GI: diarrhea, nausea, administration,
bacterial cell complicated skin and children < 12 years constipation, - Obtain specimen for culture and
CLASSIFICATION: wall synthesis skin structure old, pregnancy, vomiting, sensitivity prior to first dose of
Antiinfective; promotes loss of infections, lactation. pseudomembranous the drug; start drug pending
Beta-lactam membrane nosocomial or colitis results. Periodic CBC with
antibiotic; Anti- integrity and community-acquired differential, platelet count, Hgb &
pseudomonal leads to death pneumonia caused SKIN: hypersensitivity Hgt, and serum electrolytes.
penicillin of the organism. piperacillin-resistant, reactions ,rash, - Monitor for hypersensitivity
piperacillin/tazobacta pruritus response; discontinue drug and
m susceptible, beta- notify physician if allergic
lactamase-producing response noted.
bacteria. - Monitor for hemorrhagic
manifestations because high dose
may induce coagulation
abnormalities.
- Instruct family/significant others
to report significant, unexplained
diarrhea.
- Monitor vital signs because of
cardiac arrhythmias,
hypertension and fever as
adverse reactions.