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1011 type of B cells capable of dealing with 100 trillion types of antigens
Why need few days for B cells to produce antibodies (time lag)?
What receptors are found on B cells that will help recognize the antigens?
Cytokines to activate the B cells to divide (into larger number) and differentiate
into B plasma cells and B memory cells
Epitope on antigen
Paratope on antibodies
5.
Large pool of memory cells remaining in the blood initially, very small amount
of naïve B cells each naïve B cells can produce ten thousands antibodies
each naïve B cells proliferate effect is multiplied many times due to larger
pool of memory cells due to first exposure of antigens
http://oslovet.veths.no/compendia/LAS/KAP30.pdf
Memory cells circulate through the blood, lymph and tissues, probably not manufacturing
antibodies (Perelson et al., 1978), but when exposed to a second antigenic stimulus
commence differentiating into large lymphocytes capable of producing high affinity
antibody, preselected for the specific antigen that had stimulated the primary response.