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The University of Zambia

School of Health Sciences


Department of Biomedical Sciences
Pathology & Microbiology, PTM 3020 & PTM 3010
(Year Three BPharm and BSc Physiotherapy)
Venue: Pharmacy Hall, UTH
Immunology Component Component Coordinator: S. M. Munsaka, PhD
(smunsaka1@gmail.com, Tel/whatsapp: +260977925304
Wk Day Date Time Topic Lecturer
1 Tue 13/12/16 14:00-16:00 Introduction and overview of the immune system Munsaka

Tue Innate immunity, Inflammation, hypersensitivity and


3 10/01/17 14:00-16:00 Munjita
complement system
Term 2

5 Tue 24/01/17 14:00-16:00 Adaptive immunity (Cells, Antibodies, MHC, and TCR) Munjita

7 Tue 07/02/17 14:00-16:00 Antigens, antibody-antigen reactions Chisanga

Assessment Review Period


2 Tue 07/03/17 14:00-16:00 Immunity to infection, immune evasion and vaccines Munsaka

4 Tue 21/03/17 14:00-16:00 Immune regulation Chisanga


Term 3

Tue Disorders of immunity (immune deficiencies and


6 04/04/17 14:00-16:00 Munsaka
autoimmunity, and tumor immunology)

Assessment Review Period


1 Tue 02/05/17 14:00-16:00 Tolerance and transplant immunology Chisanga
Term 4

3 Tue 16/05/17 14:00-16:00 Immunology Assessment Test All

STUDY Mon 10/07/17 Study Break


EXAM Mon 24/07/17 Examination Period
VAC Mon 07/08/17 Vacation Starts
DEF Mon 02/10/17 Deferred and Supplementary Examinations

Teaching Staff: Dr. S. M. Munsaka, Dr. S. Munjita and Mr. C. Chisanga

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Course Outline

1.0. IMMUNOLOGY: (10 HRS)


1.0.1. INTRODUCTION TO IMMUNOLOGY
1.0.1.1. UNIT 1: GENERAL OVERVIEW OF IMMUNOLOGY
1.0.1.1.1. Impact of infectious disease
1.0.1.1.2. Immune system
1.0.1.1.3. Immune response
1.0.1.2. UNIT 2. INNATE IMMUNITY
1.0.1.2.1. Physical and chemical defences
1.0.1.2.2. Leukocytes
1.0.1.2.3. Extra cellular chemical defenses
1.0.1.2.4. Complement system
1.0.1.2.5. Acute inflammatory reaction
1.0.1.3. UNIT3: ADAPTIVE IMMUNITY
1.0.1.3.1. Cells of adaptive immunity
1.0.1.3.2. Molecules of adaptive immunity (Antibody, MHC & T cell receptor)
1.0.1.4. UNIT4: ANTIGENS
1.0.1.4.1. General features of antigens
1.0.1.4.2. Types of antigen
1.0.1.4.3. Antigen-antibody interactions
1.0.1.5. UNIT5: IMMUNITY TO INFECTION
1.0.1.5.1. Collaboration between innate and adaptive immunity
1.0.1.5.2. Adversarial strategies: Bacterial, viral and parasite escape strategies
1.0.1.5.3. Prophylaxis: Vaccination
1.0.1.6. UNIT6: IMMUNO REGULATION
1.0.1.6.1. Consequences of immune response
1.0.1.6.2. Regulatory mechanisms
1.0.1.7. UNIT7: DISORDERS OF IMMUNITY
1.0.1.7.1. Immunodeficiency: Congenital and Acquired
1.0.1.7.2. Hypersensitivity reactions
1.0.1.7.3. Autoimmunity and autoimmune diseases
1.0.1.7.4. Tumour immunology
1.0.1.8. UNIT 8: TOLERANCE AND TRANSPLANTATION
1.0.1.8.1. Mechanisms of tolerance induction
1.0.1.8.2. Induction and maintenance of tolerance
1.0.1.8.3. Histocompatibility antigens
1.0.1.8.4. Mechanisms of graft rejection
1.0.1.8.5. Prevention of graft rejection