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PEDIATRICS/ORIGINAL RESEARCH

Emergency Department Analgesia for


Fracture Pain

Julie C. Brown, MD, MPH Study objectives: We analyze records of all emergency department (ED) patients
Eileen J. Klein, MD, MPH with extremity or clavicular fractures to describe analgesic use, compare analgesia
Charlotte W. Lewis, MD, MPH
between adults and children, and compare analgesia between the subset of these
Brian D. Johnston, MD, MPH
Peter Cummings, MD, MPH
adults and children with documented moderate or severe pain. Among children, we
compare treatment between pediatric and nonpediatric facilities.
From the Department of
Methods: Analysis of the ED component of the National Center for Health Statistics
Pediatrics, University of
Washington, School of Medicine National Hospital Ambulatory Medical Care Survey for 1997 through 2000 was con-
(Brown, Klein, Lewis, ducted. The proportion of patients with closed extremity and clavicular fracture that
Johnston); the Department of received any analgesic and narcotic analgesic medications was determined for each
Epidemiology, University of
Washington School of Public
age category. Survey-adjusted regression analyses compared pain and narcotic
Health and Community medications by age and ED type (pediatric versus other). Analyses were repeated for
Medicine (Cummings); and the the subset of patients with moderate or severe pain severity scores.
Children’s Hospital and
Regional Medical Center Results: Of 2,828 patients with isolated closed fractures of the extremities or clavi-
(Brown, Klein, Lewis, cle, 64% received any analgesic and 42% received a narcotic analgesic. Pain sever-
Johnston), Seattle, WA. ity scores were recorded for 59% of visits overall, 47% of children younger than 4
years, and 34% of children younger than 1 year. Among patients with documented
moderate or severe pain, 73% received an analgesic and 54% received a narcotic
analgesic. Compared with adults, a lower proportion of children (≤15 years) received
either any analgesic or a narcotic analgesic (P<.001). After adjustment for con-
founders and survey design, the proportion of patients aged 0 to 3, 4 to 8, 9 to 15, 16
to 29, 30 to 69, and 70 years and older who received any analgesic was 54% (95%
confidence interval [CI] 41% to 67%), 63% (95% CI 57% to 68%), 60% (95% CI 57% to
64%), 67% (95% CI 62% to 73%), 68% (95% CI 64% to 72%), and 58% (95% CI 52% to
65%), respectively; the proportion who received a narcotic analgesic was 21% (95%
CI 11% to 31%), 30% (95% CI 22% to 37%), 27% (95% CI 23% to 32%), 47% (95% CI 40%
to 54%), 51% (95% CI 46% to 56%), and 41% (95% CI 35% to 48%), respectively. Com-
pared with children treated in other EDs, children treated in pediatric EDs were about
as likely to receive any analgesia (adjusted relative risk [RR] 1.1; 95% CI 0.9 to 1.3) or
narcotic analgesia (adjusted RR 0.9; 95% CI 0.6 to 1.2).

Copyright © 2003 by the American


Conclusion: In pediatric and adult patients, pain medications were frequently not
College of Emergency Physicians. part of ED treatment for fractures, even for visits with documented moderate or
0196-0644/2003/$30.00 + 0 severe pain. Pain severity scores were often not recorded. Pediatric patients were
doi:10.1067/mem.2003.275 least likely to receive analgesics, especially narcotics.
[Ann Emerg Med. 2003;42:197-205.]

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ANALGESIA FOR FRACTURE PAIN
Brown et al

INTRODUCTION This study was exempt from full institutional review


board review.
Several studies have evaluated administration of anal- We included only ED visits for closed fractures of the
gesia in the emergency department (ED) and have clavicle or extremity as 1 of the first 3 diagnoses (Figure
reported that patients frequently do not receive medica- 1). During the 4 study years, there were 3,054 visits
tion for painful conditions.1-4 Recently, the Joint with at least 1 of the following International Classifica-
Commission on Accreditation of Healthcare Organiza-
tions stated that “unrelieved pain has adverse physical
and psychological effects. The patient’s right to pain
Figure 1.
management is respected and supported.” The practice Numbers of patient visits included and excluded from the
standard to which health care organizations are now study. *Including ICD-9-CM fracture diagnoses 812, 813,
held states that “pain is assessed in all patients.”5 Given 810, 814-818, 820-827. †ICD-9-CM diagnostic categories
that specify >1 fracture within the category were not
the current literature on analgesia in ED settings and excluded (eg, ICD-9-CM code 813 for “radius and/or ulna
the emphasis of the Joint Commission on Accreditation fracture,” ICD-9-CM code 818 for “arms, multiple or
unspecified,” ICD-9-CM code 823 for “tibia and/or fibula
of Healthcare Organizations on provision of adequate fracture.”) ‡Excluding ICD-9-CM open fracture diagnoses
analgesia to patients in pain, we sought to determine 812.1-812.19, 812.3, 812.5, 813.1, 813.3, 813.5, 813.9,
whether appropriate analgesia was being provided to 810.1-810.13, 814.1, 815.1, 816.1, 817.1, 818.1, 820.1,
820.3, 820.9, 821.1, 821.3, 822.1, 823.1, 823.3, 823.9,
pediatric and adult ED patients with potentially painful 824.1, 824.3, 824.5, 824.7, 824.9, 827.1, 825.1, 825.3,
fractures during 1997 to 2000. 826.1. §Excluding ICD-9-CM trauma diagnoses 800-809,
811, 819, 850-869, 940-949, 952.
Using a national survey of ED visits, we evaluated
patients with extremity and clavicular fractures treated
in EDs. We described variations in analgesic use by age 93,109
and compared the use of analgesia for adults with that ED visits surveyed
in 1997-2000
for children. We repeated these analyses for the subset
Include all diagnoses of closed
of patients with moderate or severe pain on pain sever- fracture of the extremity or clavicle*
ity scores. In children, we also compared treatment 3,054 Visits
between pediatric and nonpediatric facilities.
Exclude all visits with fractures in
>1 fracture category†

METHODS 2,989 Visits

Exclude all visits with a diagnosis of


We used data from the ED component of the National open extremity or clavicle fracture‡
Hospital Ambulatory Medical Care Survey, which was 2,888 Visits
directed by the Centers for Disease Control and Exclude all visits involving
Prevention’s National Center for Health Statistics, for cardiopulmonary resuscitation
intubation, or ICU admission
1997 to 2000. Community and academic hospitals, 2,869 Visits
including children’s hospitals, were included in this
Exclude all visits with additional
survey, whereas federal hospitals and freestanding clin- trauma diagnoses§
ics were excluded. EDs were eligible only if they were 2,842 Visits
open and staffed 24 hours a day. The survey used a 4- Exclude all visits in which
medications are illegible, or
stage sampling design to obtain representative national coded as “medications IV”
estimates and took place during a randomly assigned 4- or “medications continued”
2,828 Visits
week data period. Data collection was performed by
trained hospital staff using a standard collection form.

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Brown et al

tion of Diseases, Ninth Revision, Clinical Modification investigators, we defined a pediatric hospital as one in
(ICD-9-CM) diagnostic codes for extremity or clavicle which more than 80% of all visits (not just visits for
fracture. The 65 visits involving fracture in more than 1 fractures) were made by patients younger than 18
ICD-9-CM category were subsequently excluded, years.7
although it was still possible to have more than 1 frac- We considered the following survey variables as
ture coded within a category (eg, a radius and an ulna potential confounders: fracture type (clavicle, humerus,
fracture). Also excluded were 101 visits involving ICD- radius or ulna, hand, femur, tibia or fibula, foot, other),
9-CM codes for open fracture; 27 visits involving car- year of study, sex, race (white, black, other), ethnicity
diopulmonary resuscitation, intubation, ICU admis- (Hispanic, non-Hispanic), source of payment (private
sion, or additional trauma diagnoses; and 14 visits in insurance, Medicare, Medicaid, workers’ compensa-
which medications were either illegible on the survey tion, self-pay, other), metropolitan area (yes/no), geo-
form or the name of the specific medication given was graphic location (Northeast, Midwest, South, West),
not listed (eg, listed as “intravenous medications” or type of provider (staff physician, resident/intern, other
“medications continued”). physician, physician assistant, nurse practitioner, reg-
The survey medication item allowed the user to istered nurse, other), type of hospital ownership (vol-
record up to 6 medications that were ordered, supplied, untary, government, proprietary), triage assessment of
administered, or continued during the visit, including the immediacy of care required (<15 minutes, 15 to 60
prescription and over-the-counter medications, immu- minutes, >1 to 2 hours, >2 to 24 hours), orthopedic care
nizations, allergy shots, and anesthetics. The medica- provided in the ED (yes or no), shift at patient arrival
tions listed were then coded by unique drug codes and (day, evening, night), admission to the hospital (yes or
also categorized by using a drug class variable based on no), pain severity score on presentation (none, mild,
the National Drug Code Directory of Drug Classes.6 We moderate, or severe), and pediatric versus nonpediatric
found that the drug class variables were missing a few hospital. The information on race and ethnicity was
pain medications otherwise identified by unique drug based on the provider’s knowledge of the patient or by
codes. To ensure that all pain medications were in- observation because providers were not directed or
cluded in the drug class variables, we took the following expected to ask the patient for this information.7
steps: to the narcotic medication drug class variable we In all analyses, we accounted for the primary sam-
added Vicodin (drug code 34110), Lortab (92180), pling units, the sampling strata, and the probability
Lorcet (93089), Tylox (32945), Tylenol with codeine sampling weights used in the survey by using lineariza-
(32915, 32920, 32925, 32930, 32935), morphine sul- tion methods in Stata software (version 7.0, Stata
fate (99123), meperidine (18760), codeine (7180), Hy- Corporation, College Station, TX).8 Four strata con-
phen (93077) and hydrocodone (14955); to the pain tained a single primary sampling unit; we therefore col-
medication drug class variable we added morphine sul- lapsed these 4 strata into 2 with 2 primary sampling
fate (99123) and hydrocodone (14955). units each.
For data description, we used 6 categories of age: 3 We used linear regression to assess whether the
pediatric categories (0 to 3, 4 to 8, and 9 to 15 years) and adjusted proportion of patients receiving any analgesic
3 adult categories (16 to 29, 30 to 69, and ≥70 years). or a narcotic analgesic varied by category of age.
For regression analyses, we used 17 age categories (<1 Although our study outcome, receipt of pain medica-
year; 1 year; and 2 to 3, 4 to 5, 6 to 7, 8 to 9, 10 to 12, 13 tion, was binary (and therefore not normally dis-
to 15, 16 to 19, 20 to 29, 30 to 39, 40 to 49, 50 to 59, 60 tributed), in a reasonably large study such as ours, pro-
to 69, 70 to 79, 80 to 89, and ≥90 years). No survey vari- portions can be thought of as means that are normally
able identified which hospitals were dedicated pedi- distributed under the central limit theorem.9 Some
atric facilities. In keeping with the practice of other results were presented as mean proportions receiving

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Brown et al

medication by age group, adjusted for the mean values inadequate analgesia, were not found to be confounders
of any confounding variables in the regression. of the relationship between age and analgesic use.11-16
We used Poisson regression10 to estimate risk ratios For 71% of the patients studied, there was documen-
for analgesic or narcotic analgesic use according to pain tation that at least 1 medication was ordered, supplied,
severity score and whether the hospital was pediatric administered, or continued during the visit (including
(among children aged ≤15 years). The variables frac- prescription and over-the-counter medications). These
ture type, year, geographic location, admission to the medications included an analgesic in 64% of patients
hospital, and need for orthopedic care were considered studied and a narcotic analgesic, either alone or in a
likely confounders and were included in all regression combination product, in 42% of patients studied. Pain
models. In addition, we adjusted for any other variable medication use varied only modestly throughout the 4
that changed the risk ratios by more than 10%. years of the study, from 62% in 1997 to 66% in 2000;
All of the statistical analyses assumed that observa- narcotic use similarly varied from 40% in 1997 to 45%
tions were independent in the sense that no individual in 2000 (linear regression tests for trend were not sig-
was included more than once in the data. Because the nificant; P>.05 for both tests).
survey recorded patient visits only and did not include Our first analysis described the use of analgesics and
patient identifiers, it was possible for a patient to be in narcotic analgesics by age for all patients. The propor-
our data more than once. However, given the nature of tions of patients who received any analgesic or a nar-
these injuries and the large number of participating cotic analgesic were lower in pediatric and elderly
hospitals (283 to 309 participating hospitals a year, patients, with more prominent differences in narcotic
with no more than 11 patients per hospital a year), it is medication use (Table 2, Figure 2). This trend was most
unlikely that there were many, if any, patients included noticeable in children younger than 4 years; only 54%
more than once. of these children received any analgesics, and only 21%
received narcotic analgesics. Our second analysis tested
R E S U LT S
for differences in analgesic use across age categories.
The differences in any analgesic and narcotic analgesic
During the 4 study years, there were 2,828 ED visits for use were statistically different across the 17 age cate-
isolated closed fractures of the extremities or clavicle gories (P<.001 for both tests).
that met inclusion and exclusion criteria in the sample Our third analysis evaluated the use of analgesics and
(Figure 1), which represents a national estimate of 12.5 narcotic analgesics by age for patients with documented
million ED visits a year. The characteristics of these moderate or severe pain. To begin, we characterized
patients are shown in Table 1. Children younger than 16 patients for whom information on pain severity was
years had more arm fractures than adults and fewer available. Pain severity scores were recorded for 59% of
hand and foot fractures. Compared with other age patients. The proportion of patients who had pain
groups, children aged 9 to 15 years were more likely to severity scores recorded was similar throughout the 4
be male, and patients 70 years and older were more years of the study. For patients with any pain severity
likely to be female. Compared with older children and score, the proportion with moderate or severe pain also
adults, a higher proportion of children younger than 4 did not change throughout the 4 years of study. Young
years were of minority races, from metropolitan areas, children were less likely to have a pain severity score
and from the southern United States. Adults aged 30 recorded (Table 2). However, patients who had a pain
years or older were more likely to be admitted to the severity score recorded by ED staff (including a judg-
hospital than patients younger than 30 years. Race and ment of no pain) were not much more likely to receive
ethnicity, which have been reported as risk factors for any analgesic than patients with no record of their pain

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status (any analgesic, adjusted relative risk [RR] 1.1; cotic use (adjusted RR 1.5; 95% CI 1.3 to 1.7). However,
95% confidence interval [CI] 0.99 to 1.2). Patients who the use of analgesics among patients with documented
had any pain severity score recorded were somewhat moderate to severe pain remained low: only 73% re-
more likely to have received a narcotic compared with ceived any pain medication and 54% received narcotics
patients for whom no information about pain severity (Table 2, Figure 3). Children younger than 1 year were
was recorded (adjusted RR 1.3; 95% CI 1.1 to 1.4). unlikely to have documented moderate to severe pain,
Next, we evaluated patients with documented mod- but when they did, they were likely to receive anal-
erate or severe pain. Compared with a pain severity gesics. In patients aged 4 to 15 years, in which the pro-
score of none or mild, the presence of documented portions with documented pain severity scores were
moderate or severe pain was associated with pain medi- more comparable to that of the adult groups, the pro-
cation use (adjusted RR 1.3; 95% CI 1.2 to 1.4) and nar- portion of children with moderate or severe pain receiv-

Table 1.
Baseline characteristics of patients with closed clavicle or extremity fractures.

Age Category, No. (%)


Characteristic All Ages, No. (%) 0–3 y 4–8 y 9–15 y 16–29 y 30–69 y ≥70

Total visits, No. (%)* 2,828 (100) 102 (3) 232 (9) 487 (19) 514 (18) 1,039 (36) 454 (16)
Closed fracture category
Clavicle 126 (4) 14 (9) 6 (1) 37 (6) 23 (3) 37 (4) 9 (2)
Humerus 242 (9) 12 (15) 33 (18) 33 (8) 25 (4) 71 (7) 68 (16)
Radius/ulna 516 (19) 30 (30) 86 (34) 134 (28) 66 (14) 150 (14) 50 (12)
Hand 756 (27) 17 (16) 52 (20) 163 (34) 223 (43) 250 (24) 51 (10)
Femur 264 (9) 5 (5) 8 (3) 9 (2) 7 (2) 56 (5) 179 (38)
Tibia/fibula 458 (15) 16 (18) 22 (10) 52 (10) 81 (14) 227 (21) 60 (14)
Foot 385 (14) 6 (5) 14 (7) 49 (11) 83 (19) 210 (20) 23 (4)
Other 81 (3) 2 (2) 11 (6) 10 (2) 6 (1) 38 (5) 14 (3)
Male sex 1,466 (52) 54 (52) 129 (55) 346 (70) 340 (65) 496 (47) 101 (22)
Race
White 2,375 (85) 81 (77) 190 (84) 409 (86) 415 (84) 854 (82) 426 (94)
Black 369 (12) 15 (17) 33 (13) 58 (10) 84 (14) 158 (15) 21 (5)
Other 84 (3) 6 (7) 9 (3) 20 (3) 15 (3) 27 (3) 7 (1)
Metropolitan area 2,320 (74) 88 (82) 195 (75) 387 (73) 411 (71) 878 (77) 361 (73)
Geographic location
Northeast 102 (19) 20 (13) 46 (12) 119 (17) 125 (19) 278 (21) 115 (20)
Midwest 232 (29) 22 (24) 74 (35) 129 (28) 153 (33) 255 (27) 115 (29)
South 487 (31) 36 (41) 68 (32) 134 (33) 141 (29) 299 (31) 134 (30)
West 514 (21) 24 (22) 44 (21) 105 (22) 95 (19) 207 (20) 90 (20)
Pediatric hospital† 66 (3) 16 (21) 27 (12) 21 (5) 2 (<1) 0 (0) 0 (0)
Pain on presentation
None or mild 646 (24) 18 (22) 56 (23) 127 (25) 138 (30) 224 (22) 83 (19)
Moderate or severe 977 (35) 28 (25) 85 (39) 150 (32) 149 (28) 380 (38) 185 (42)
No pain score 1,205 (41) 56 (53) 91 (38) 210 (43) 227 (42) 435 (40) 186 (39)
ED care
Extremity radiographs done 2,188 (79) 80 (82) 190 (84) 393 (83) 403 (79) 806 (78) 316 (71)
Other radiographs done 484 (16) 15 (11) 24 (10) 58 (11) 81 (17) 167 (14) 139 (28)
Treated by staff physician 2,544 (90) 94 (92) 205 (90) 428 (88) 459 (89) 934 (90) 424 (93)
Orthopedic care 1,959 (71) 70 (73) 175 (73) 388 (83) 377 (74) 703 (68) 246 (55)
Admitted to hospital 371 (13) 5 (6) 16 (7) 13 (3) 29 (5) 117 (11) 191 (41)
*All proportions are adjusted for survey design.
†A pediatric hospital is defined as one in which >80% of visits (not just visits for fractures) were made by patients aged <18 years.

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Brown et al

ing any analgesic and narcotic analgesics remained children younger than 16 years who were treated in
lower than that for adults younger than 90 years. The pediatric EDs had a median age of 7 years compared
proportion of elderly patients who were older than 90 with 10 years for the 758 children who were younger
years, had moderate or severe pain, and received pain than 16 years and were treated in general EDs. The chil-
medications and narcotics was lower than that of dren who were younger than 16 years and treated in
younger adults and similar to that of children. pediatric EDs were less likely to have pain severity
Our fourth analysis tested for differences in analgesic scores recorded than the children who were younger
use across age categories for patients with moderate or than 16 years and treated in general EDs (34% versus
severe pain. For these patients, the differences in pain 64%, respectively; adjusted RR 0.6; 95% CI 0.5 to 0.9).
medication use and narcotic use across the 17 age cate- In pediatric and other EDs, similar proportions of chil-
gories were statistically significant (P<.001 for both
comparisons).
Our final analysis compared analgesic use for chil-
Figure 2.
dren treated in pediatric versus general EDs. The 64 A, Point estimates with 95% CIs showing the proportion of
patients with closed clavicle or extremity fractures who
received any analgesia (adjusted for survey design, fracture
type, year, hospital admission, orthopedic care, and geo-
Table 2. graphic location) (N=2,828). B, Point estimates with 95%
Proportion of patients who had closed clavicle or extremity CIs showing the proportion of patients with closed clavicle or
fractures and received pain and narcotic analgesia (adjusted extremity fractures who received narcotic analgesia (adjusted
for survey design, fracture type, year, hospital admission, for survey design, fracture type, year, hospital admission,
orthopedic care, and geographic location). orthopedic care, and geographic location) (N= 2,828).

Proportion Proportion A 1
Receiving Any Receiving
receiving any analgesia

Analgesic Narcotic
Adjusted proportion

0.8
No. of Agents (95% (95%
Population/ Patients Confidence Confidence 0.6
Age, y (% Total)* Limits) Limits)
0.4
All patients
0–3 102 0.54 (0.41, 0.67) 0.21 (0.11, 0.31) 0.2
4–8 232 0.63 (0.57, 0.68) 0.30 (0.22, 0.37)
9–15 487 0.60 (0.57, 0.64) 0.27 (0.23, 0.32) 0
16–29 514 0.67 (0.62, 0.73) 0.47 (0.40, 0.54)
30–69 1,039 0.68 (0.64, 0.72) 0.51 (0.46, 0.56) 5 15 25 35 45 55 65 75 85 95
≥70 454 0.58 (0.52, 0.65) 0.41 (0.35, 0.48)
Age, y
Patients with any pain
score recorded
0–3 46 (47) 0.56 (0.40, 0.72) 0.32 (0.17, 0.46) B
4–8 141 (62) 0.63 (0.56, 0.71) 0.28 (0.18, 0.39) 1
receiving narcotic analgesia

9–15 277 (57) 0.61 (0.56, 0.66) 0.32 (0.26, 0.39)


0.8
Adjusted proportion

16–29 287 (58) 0.67 (0.60, 0.74) 0.49 (0.41, 0.57)


30–69 604 (60) 0.73 (0.67, 0.79) 0.56 (0.48, 0.64)
≥70 268 (61) 0.60 (0.52, 0.67) 0.43 (0.35, 0.52) 0.6
Patients with moderate
to severe pain recorded 0.4
0–3 28 (25) 0.62 (0.41, 0.84) 0.45 (0.24, 0.66)
4–8 85 (35) 0.76 (0.63, 0.88) 0.43 (0.26, 0.59) 0.2
9–15 150 (28) 0.68 (0.59, 0.77) 0.41 (0.30, 0.51)
16–29 149 (38) 0.79 (0.71, 0.87) 0.59 (0.48, 0.89) 0
30–69 380 (42) 0.78 (0.71, 0.85) 0.63 (0.55, 0.70)
≥70 185 (35) 0.62 (0.51, 0.72) 0.47 (0.39, 0.55) 5 15 25 35 45 55 65 75 85 95
*Adjusted for survey design only. Age, y

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dren younger than 16 years had moderate to severe pain DISCUSSION


when pain severity scores were used (adjusted RR 1.1;
95% CI 0.6 to 1.9), and similar proportions of children A third of the fracture patients in our study did not re-
younger than 16 years had documented treatment with ceive any pain medications. The proportion of patients
any analgesic (adjusted RR 1.1; 95% CI 0.9 to 1.3) or a receiving pain medications was even lower in children.
narcotic analgesic (adjusted RR 0.9; 95% CI 0.6 to 1.2). Pain severity scores appear to be underused in the ED
Results were similar when children younger than 5 setting. Pain scores were recorded in only 59% of patients
years were analyzed separately. overall, and in only 47% of children younger than 4
years. Even when pain scores were recorded as moderate
or severe, analgesics were not routinely used. For
patients with documented moderate to severe pain,
Figure 3. 73% overall and 62% of patients younger than 4 years
A, Point estimates with 95% CIs showing the proportion of received any analgesia.
patients with closed clavicle or extremity fractures and docu-
mented pain severity scores who received any analgesia Our findings are in keeping with previous North
(adjusted for survey design, fracture type, year, hospital American studies of pain management in the ED. In pre-
admission, orthopedic care, and geographic location)
(N=977). B, Point estimates with 95% CIs showing the pro- vious reports, the proportion of adults receiving analge-
portion of patients with closed clavicle or extremity fractures sia for painful conditions ranged between 31% and
and documented pain severity scores who received narcotic 74%.1,4,14,17-20 This range was the same for studies lim-
analgesia (adjusted for survey design, fracture type, year,
hospital admission, orthopedic care, and geographic location) ited to fractures. The proportion of children receiving
(N=977). analgesia for painful conditions ranged between 25%
and 96%.3,4,17,18,21,22
As in this study, previous studies comparing adult
A 1
and pediatric patients have reported that children re-
receiving any analgesia

ceive less analgesia than adults.4,17,23,24 Schechter et


Adjusted proportion

0.8

0.6
al23 retrospectively compared narcotic use for hospital-
ized patients with 4 diagnoses: hernias, appendec-
0.4
tomies, burns, and fractured femurs. They found that
0.2 adults received significantly more doses of narcotics
0
than children (2.2 versus 1.1 doses; P=.0001). Infants
and young children were less likely than older children
5 15 25 35 45 55 65 75 85 95
Age, y to have narcotics prescribed. Selbst and Clark17 studied
268 patients with painful conditions (ie, sickle cell
B 1 crises, lower-extremity fractures, second- or third-
receiving narcotic analgesia

degree burns) and reported that 28% of children and


0.8
Adjusted proportion

60% of adults received analgesia. In an analysis of the


0.6
National Hospital Ambulatory Medical Care Survey for
0.4 1992 to 1997, 5.6% of children versus 7.8% of adults
0.2 received parenteral sedation or analgesia for orthopedic
0 injuries (P=.05).24 This analysis was not adjusted for
fracture type, pain severity score, or survey design.
5 15 25 35 45 55 65 75 85 95 Petrack et al4 retrospectively compared use of anal-
Age, y gesia in 120 children and 120 adults treated for long
bone fractures between 1993 and 1994 in 1 of 3 settings:

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Brown et al

academic centers with combined adult and pediatric series, adverse events were noted in only 2.3% of 1,180
EDs, community EDs, and academic centers with sepa- pediatric patients who underwent procedural sedation
rate adult and pediatric EDs. Overall, pediatric patients and analgesia in the ED, with no serious complications
were significantly less likely to receive analgesia while noted.30
in the ED than adults (53% versus 73%; P=.05). In sepa- In the analysis of patients with moderate to severe
rate analyses of each center, the differences between pain, a higher than average proportion of infants (chil-
children and adults were significant at the academic dren <1 year) received analgesia compared with all
centers with combined pediatric and adult EDs (58% other age categories, which most likely reflects a differ-
versus 88%, respectively; P<.003) and the community ence in the use of pain severity scores. Compared with
EDs (38% versus 65%; P<.02) but not at the academic all other age groups, a lower proportion of infants had
centers with separate adult and pediatric EDs (65% ver- pain severity scores recorded. It is not surprising that
sus 68%).4 These findings are contrary to our results of the small subset of infants who received pain severity
no difference in analgesia provided to children in pri- scores also received analgesia. This does not mean we
mary pediatric EDs compared with general EDs. are doing well caring for infants, because most infants
Although it is possible that the study by Petrack et al did not have pain scores and did not receive analgesia. It
was detecting regional differences that are not apparent probably means that the small subset of infants who had
nationally, it seems more likely that this difference in someone paying enough attention to their pain to give
results is caused by variation in hospital case mix be- them a pain score also paid enough attention to give
tween the 2 studies. In our study, we were unable to sep- them analgesia.
arate academic from community hospitals. Although it We believe this is the largest detailed study to date
is likely that EDs treating more than 80% pediatric comparing pediatric and adult analgesia for fracture
patients are connected with pediatric academic centers, pain. The study has several limitations. The survey
we do not have detailed information about the remain- medication item allowed the user to record medications
ing EDs, and we cannot analyze the use of analgesia by that were ordered, supplied, administered, or contin-
specific general hospital type. ued during the visit. It is possible that some patients
In our study, pain medication use was lowest at the 2 received medications before arrival that were not con-
extremes of age, suggesting that providers may be less tinued during the visit and thus not recorded. Although
comfortable assessing pain and providing pain relief for directed to list all medications, including over-the-
the very old and the very young. Some providers may be counter medications, some hospital staff may have
concerned about their ability to assess pain in nonver- neglected to list all analgesics given, especially if over-
bal patients, but simple pain scales can be used for non- the-counter pain medications were routinely adminis-
verbal or verbal but illiterate patients. These scales, tered by nursing staff in triage. It is also possible that
such as the Modified Infant Pain Scale; Face, Legs, providers evaluated their patient’s pain severity without
Activity, Cry, Consolability pain rating scale; and the recording this information on the survey. Finally, there
Wong-Baker Faces pain rating scale have been validated was no way to distinguish visits for acute fracture man-
in infants and young children.25-28 Alternatively, agement from visits for follow-up care or fracture com-
providers may be concerned about the safety of anal- plications. However, 97% of the patients with pain
gesics, particularly narcotic medications. However, scores reported pain, and analgesics were given to a sim-
narcotic medications have been shown to be safe even ilar proportion of patients with and without pain scores.
in young children. In 1 study of fentanyl-induced respi- Thus, it is likely that analgesia was indicated for the
ratory depression, the authors did not detect a differ- majority of patients, regardless of the timing of injury.
ence in respiratory depression between children older The results of this survey indicate that ED analgesic
than 3 months and adults.29 In a large prospective case use for extremity and clavicular fractures remained low

2 0 4 ANNALS OF EMERGENCY MEDICINE 42:2 AUGUST 2003


ANALGESIA FOR FRACTURE PAIN
Brown et al

and the use of pain severity scores inadequate, from 8. Levy PS, Lemeshow S. Sampling of Populations: Methods and Applications. New
York, NY: John Wiley; 1999:365-370.
1997 through 2000. Children and elderly patients were
9. Lumley T, Diehr P, Emerson S, et al. The importance of the normality assumption in
least likely to receive analgesics. It is widely known that large public health data sets. Ann Rev Public Health. 2002;23:151-169.
assessment and management of pain should be part of 10. Long JS. Regression Models for Categorical and Limited Dependent Variables.
Thousand Oaks, CA: SAGE Publications; 1997:217-250.
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with disorders likely to be painful. We conclude that gency department analgesia. JAMA. 1993;269:1537-1539.

additional effort and resources are needed to address 12. Todd KH, Lee T, Hoffman JR. The effect of ethnicity on physician estimates of pain
severity in patients with isolated extremity trauma. JAMA. 1994;271:925-928.
the issue of undertreatment of pain in children and 13. Todd KH. Pain assessment and ethnicity. Ann Emerg Med. 1996;27:421-423.
adults with fractures in the ED setting. Special attention 14. Todd KH, Deaton C, D’Adamo AP, et al. Ethnicity and analgesic practice. Ann
should be given to analgesia in the very old and very Emerg Med. 2000;35:11-15.
15. Todd KH. Influence of ethnicity on emergency department pain management. Emerg
young. Educating providers on nonverbal options for Med. 2001;13:274-278.
measuring pain, especially in young children, may 16. Yen K, Kim M, Stremski ES, et al. The effect of ethnicity and race on the use of pain
medications on children with long bone fractures in the emergency department: use of
improve measurement and documentation of pain sta- a national database. Acad Emerg Med. 2001;8:447-448.
tus and facilitate recognition and treatment of pain in 17. Selbst SM, Clark M. Analgesic use in the emergency department. Ann Emerg Med.
these vulnerable populations. 1990;19:1010-1013.
18. Lewis LM, Lasater LC, Brooks CB. Are emergency physicians too stingy with anal-
gesics? South Med J. 1994;87:7-9.
Author contributions: JCB and EJK conceived and designed the 19. Jones JS, Johnson K, McNinch M. Age as a risk factor for inadequate emergency
study, drafted and revised the manuscript, and performed the anal- department analgesia. Am J Emerg Med. 1996;14:157-160.
ysis and interpretation. JCB, CWL, and BDJ managed the dataset. 20. Ngai B, Ducharme J. Documented use of analgesics in the emergency department
CWL, BDJ, and PC reviewed the manuscript and assisted with the and upon release of patients with extremity fractures. Acad Emerg Med. 1997;4:1176-1178.
analysis. PC provided statistical consultation regarding accuracy 21. Friedland LR, Pancioli AM, Duncan KM. Pediatric emergency department analgesic
of the analysis and presentation of the results. JCB takes responsi- practice. Pediatr Emerg Care. 1997;13:103-106.
bility for the paper as a whole. 22. Chan L, Russell TJ, Robak N. Parental perception of the adequacy of pain control in
their child after discharge from the emergency department. Pediatr Emerg Care.
Received for publication January 31, 2003. Revision received March 1998;14:251-253.
26, 2003. Accepted for publication April 1, 2003. 23. Schechter NL, Allen DA, Hanson K. Status of pediatric pain control: a comparison
of hospital analgesic usage in children and adults. Pediatrics. 1986;77:11-15.
The authors report this study did not receive any outside funding or
24. Hostetler MA, Auinger P, Szilagyi PG. Parenteral analgesic and sedative use among
support. ED patients in the United States: combined results from the National Hospital Ambula-
tory Medical Care Survey (NHAMCS) 1992-1997. Am J Emerg Med. 2002;20:139-143.
Address for reprints: Julie C. Brown, MD, MPH, Children’s Hospital
25. Buchholz M, Karl HW, Pomietto M, et al. Pain scores in infants: a modified infant
and Regional Medical Center, 4800 Sand Point Way NE, Mailstop
pain scale versus visual analogue. J Pain Symptom Manage. 1998;15:117-124.
5D-1, Seattle, WA 98105; 206-987-2599, fax 206-729-2070; E-mail
26. Merkel SI, Voepel-Lewis T, Shayevitz JR, et al. The FLACC: a behavioral scale for
julbrown@u.washington.edu. scoring postoperative pain in young children. Pediatr Nurs. 1997;23:293-297.
27. Wong DL. Assessing pain at face value [letter]. Am J Nurs. 1999;99:16.
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