IX.

DRUG STUDY

NAME OF DOSAGE INDICATION/ MODE OF ADVERSE NURSING

ACTION RESPONSIBILITIES
DRUG CONTRAINDICATION REACTION

Generic Name: 500 mg Indication: Inhibits growth of CNS: confusion, fatal  Consider 10
amoeba by intracranial bleeding, Golden
Metronidazole  Acute infection binding to DNA, hallucination
with susceptible resulting in loss Rights of
Frequency: Q6 CV: hypotension
anaerobic off helical administering
Brand Name: bacterial structure, strand EENT: epistaxis, rhinitis, medication
 Acute intestinal breakage
Flagyl Route: IV taste disorder
amoebiasis inhibition of
nucleic acid GI: hemorrhage,  Instruct to
synthesis and cell abdominal pain, take drug with
Classification: Contraindication: death constipation, diarrhea,
dyspepsia, gastritis, ulcers foods or milk
Antibiotic  Active organic to decrease GI
disease of the GU: UTI, hematuria
Antibacterial upset
CNS
Hematologic: thrombotic
Amebicide  Drug allergy
thrombocytopenic purpura
 Blood dyscrasia  Inform that
Antiprotozoal
MUSCULOSKELETAL: drug may turn
arthralgia, myalgia,
arthritis urine brown,
don’t be
RESPIRATORY:
alarmed
bronchospasm, interstitial
pneumonitis, respiratory
tract bleeding

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IX. DRUG STUDY

SKIN: rash, puritis,

bruising, edema, eczema,
erythema multiforme,
urticarial, Stevens Johnson
syndrome, toxic epidermal
necrolysis

Reference: Jones & Bartlett Learning; 2011 Nurse’s Drug Handbook Tenth Edition

54
IX. DRUG STUDY

NAME OF DOSAGE INDICATION/ MODE OF ADVERSE NURSING

ACTION RESPONSIBILITIES
DRUG CONTRAINDICATION REACTION

Generic Name: 10 mg TIV Indication: Depress the CNS, CNS:dizziness, drowsiness,  Consider 10
probably by lethargy, Golden Rights
Diazepam FrequencyQ6 Adjunction in the potentiating hangover,headache,depression of
management of anxiety, GABA, an administering
preoperative sedation, CV: hypotension medication
inhibitory
con.scious sedation.  Monitor vital
Brand Name: Route: IV neurotransmitter EENT:blurred vision sign prior to
Valium periodically
Produces skeletal GI:constipation, diarrhea, throughout
Contraindication: muscle relaxation nausea, vomitting therapy and
Classification:
by inhibiting frequently
Antianxiety Contraindicated in spinal SKIN: rashes during IV
agents, patients hypersensitive polysynaptic therapy
anticonvulsant, to drug or its afferent pathways  Prolonges
components, in those high-dose
sedative/
with a history of Has therapy
hyptonics, skeletal maylead to
hypersensitivity or anticonvulsant
muscle relaxants psychological
hematologic reaction to properties due to
or physical
other thienopyridines, enhanced
dependence.
and in those with presynaptic Restrict
pathologic bleeding inhibitions. amount of
(such as peptic ulcer or drug available
intracranial hemorrhage) in patient.
Observe
depressed
patient closely
for suicidal

55
IX. DRUG STUDY

tendercies
 Observed and
record
intensity,
duration and
location of
seizure
activity. The
initial dose of
diazepam
offers seizure
control for 15-
20 mins
afteradministra
tion
Reference: Jones & Bartlett Learning; 2011 Nurse’s Drug Handbook Tenth Edition

56
IX. DRUG STUDY

NAME OF DOSAGE INDICATION/ MODE OF ADVERSE NURSING

ACTION RESPONSIBILITIES
DRUG CONTRAINDICATION REACTION

Generic Name: 40 mg Indication:  Gastric CNS:headache, dizziness,  Consider 10

acid pump asthenia, vertigo, Golden
omeprazole  Short-term inhibitor, insomnia, apathy, anxiety,
treatment of active paresthesia, dream Rights of
Frequency:OD suppresses
duodenal ulcer, gastric acid abnormalities administering
Brand Name: first line therapying secretion
CV: hypotension medication
treatment of heart by specific
Losec Route: IV burn or symptoms inhibition EENT: epistaxis, rhinitis,
of GERD of the  Monitor
taste disorder
 Short-term hydrogen patient
Classification: treatment of active potassium GI: hemorrhage,
benign gastric ulcer ATPase abdominal pain,
Antisecretory drug
 GERD, severe constipation, diarrhea,  Report severe
enzyme
Proton pump erosive esophagitis, system at nausea, vomiting, tongue headache,
inhibitor poorly responsive the atrophy worsening of
symptomatic secretory
GERD RESP; URI symptoms, symptoms,
surface of
cough, epistaxis, other fever, chills
the gastric
cancer in preclinical
parietal
studies, back pain, fever
cells;

57
IX. DRUG STUDY

Contraindication: blocks the

spinal step
 Contraindicated of acid
with production
hypersensitivity to
omeprazole or its
components, use
cautiously with
pregnancy,
lactation
Reference: Jones & Bartlett Learning; 2011 Nurse’s Drug Handbook Tenth Edition

58
IX. DRUG STUDY
NAME OF DOSAGE INDICATION/ MODE OF ADVERSE NURSING
ACTION RESPONSIBILITIES
DRUG CONTRAINDICATION REACTION

59
IX. DRUG STUDY

Generic Name: 0.5 ml Indication:
Anti-tetanus serum Tetanus toxoid is
indicated for booster
Route: IM injection only for a person
7 years old and older
Brand Name:
against tetanus
Tetanus toxoid
Primary immunization
schedule for children
under 7 yrs of age should
consist of five doses of
Classification: vaciine containing tetaus
toxoid
vaccine
Contraindication:
 Hypersensitity to
acetaminophen or
phenacetin; use
with alcohol
Clostridium tetani Redness, warmth, edema  Consider 10
culture is grown in induration with or without Golden Rights
a peptone-based tenderness as well as of
medium containing urticaria,and rash, malaise, administering
medication
an exact of bovine transient fever, pain,
 Assess allergic
muscle tissue and hypotension, nausea and
reaction
detoxified with arthralgia  Shake well
formaldehyde. before
Tetanus toxoid for widrawing
IM injection, is a each dose
sterile suspension  Special care
of alum- should be
taken to ensure
precipitated toxoid
that the
in anisotonic injection does
sodium chloride not enter blood
solution vessel

Reference: Jones & Bartlett Learning; 2011 Nurse’s Drug Handbook Tenth Edition

NAME OF DOSAGE INDICATION/ MODE OF ADVERSE NURSING

ACTION RESPONSIBILITIES
DRUG CONTRAINDICATION REACTION

60
IX. DRUG STUDY

Generic Name: 500 mg Indication: Paracetamol may Hematologic; hemolytic  Consider 10

cause analgesia by anemia, leukopenia, Golden
Paracetamol  Active organic inhibiting neutropenia,
disease of tto cnsprogstaglandins thrombocytopenia, Rights of
Frequency: TIV
relieved mild to synthesis. The thrombocytopenia administering
Brand Name: moderate pain mechanism of
Hepetic: liver damage, medication
due to things such morphine is
Biogesic Route: IV as headache, believed to involve jaundice  Assess fever
muscle and join decreased or pain: type
Metabolic: hypoglycemia
pain, backpain permeability of the of pain,
Classification: and period pain. It cell membrane to SKIN: Rashes, urticuria
is also used to location,
sodium, which
Anttipyretic bring down a high results in intensity,
Analgesic ( temperature diminished duration ,
nonopiods) Contraindication: transmission of
temperature,
pain impulses
 Hypersensitity to therefore analgesia and
acetaminophen or diaphoresis
phenacetin; use
 Assess
with alcohol
allergic
reaction: rash,
urticaia, if
these occurs
drug may
have to be

61
IX. DRUG STUDY

discontinued
Reference: Jones & Bartlett Learning; 2011 Nurse’s Drug Handbook Tenth Edition

62