Contrast Agents/Media Global Market

–Forecast to 2025

Contrast Agents/Media Global Market estimated to be worth $6,879.0 million by

2025

IQ4I Research & Consultancy published a new report on “Contrast Agents Global
Market – Forecast To 2025” This report analyzes and studies the overall market, major
Drivers & Opportunities, Restraints & Threats in North America, Europe, Asia-Pacific and
Rest of the World.

IQ4I’s Report Contains 130 market data tables and 143 figures spread through 415
pages and an exhaustive TOC on “Contrast Agents Global Market”, [Molecule (Iodine
{Ionic (Monomeric & Dimeric), Non-Ionic (Monomeric & Dimeric); Gadolinium (Linear
(Ionic & Non-Ionic), Macrocyclic (Ionic & Non-Ionic)}, Microbubble and others);
Modality(X-Ray/CT, MRI & Ultrasound); Application (Cardiovascular, Cancer,
Gastrointestinal, Musculoskeletal, Neurology, Nephrology, Obstetric & Gynecology,
Urology and others); Route of Administration (Intravascular, Oral, Rectal and others);
Imaging (Diagnostic and Interventional imaging); End Users (Hospitals, Diagnostic Centers
& Ambulatory centers and Others); Regional (North America, Europe, Asia Pacific and Rest
of the World)]

Contrast agents/Media are substances that improve the visibility of specific organs, tissues
or blood vessels and help in diagnostic imaging and interventional procedures using medical
imaging tools. These substances are introduced by swallowing or injection into a specific
area of the body and are absorbed or excreted through urine or bowel movements. Contrast
agents used are usually Iodine based, Gadolinium-based, Microbubble based contrast agent
and other which include Iron-based and barium based contrast agents. Iodine-based and
Barium-sulfate contrast agents are used in X-ray and computed tomography (CT) imaging
exams wherein the presence of Iodine-based and Barium-sulfate contrast materials at a
specific area of the body will block or limit the ability of X-rays to pass through and change
their state of appearance on X-ray or CT images. Gadolinium-based contrast agents are
preferred in MRI (Magnetic Resonance Imaging) scan in order to improve the clarity of the
images of the body’s internal structures. Microbubbles based contrast media is used during
ultrasound scans wherein the microbubbles present in suspension strongly interact with the
ultrasound beam and easily detectable by ultrasound imaging systems.

As estimated by IQ4I Research, the contrast agents global market expected to reach
$6,879.0 million by 2025.The increase in diagnostic imaging procedures and interventional
imaging procedures, increase in incidence and prevalence of disease conditions, increasing
in aging population, expansion in indications of contrast media, growth of medical imaging
technologies in emerging market, increasing research activities for contrast agents, and

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favourable reimbursements are driving the market growth. However, adverse effects related
to contrast agents and shortage of radiologists is restraining the market growth. Stringent
regulations and availability of alternative products are hampering the market expansion.

The contrast agents global market by molecule is segmented into Iodine based [Ionic
(Monomeric and Dimeric), Non-Ionic (Monomeric and Dimeric)], Gadolinium-based contrast
agents [Macrocyclic (Ionic and Non-Ionic), Linear (Ionic and Non-Ionic)], Microbubble based
contrast agent and others which include Barium, iron and dyes. Iodine-based contrast
agents market held the largest market share in 2018 and microbubble segment is growing at
high double digit CAGR from 2018 to 2025 due to expansion in disease indications.

The contrast agents by modality are segmented into X-Ray/CT, MRI, and Ultrasound. X-
Ray/CT market commanded the largest market revenue in 2018 and ultrasound segment is
growing at fast/rapidly at double digit CAGR from 2018 to 2025 due to increase in incidence
and prevalence of disease conditions, increase in aging population who are more prone to
cardiovascular disease.

The contrast agents by applications is segmented into cardiovascular, cancer,

gastrointestinal, musculoskeletal, neurology, nephrology, obstetrics & gynecology, urology
and others which include neck imaging, liver imaging, and salivary gland imaging.
Cardiovascular market accounted the largest share and is the fastest growing market at mid
single digit CAGR from 2018 to 2025 due to increase in number of cardiac imaging
procedures using Iodine, Gadolinium and microbubble contrast agents. Contrast agents
market by route of administration is segmented into intravascular, oral, rectal and others
which include intraosseous, intrathecal and intravesically. Intravascular accounted for largest
share and is the fastest growing market from 2018 to 2025 due to increase in incidence and
prevalence of cardiovascular, cancer, neurology, nephrology related conditions which
require Iodine, Gadolinium and microbubble contrast agents to be administered.

Contrast agents market by imaging is segmented into diagnostic and interventional imaging.
Diagnostic imaging market held the largest market share in 2018 and interventional imaging
segment is growing at fast/rapidly at double digit CAGR from 2018 to 2025 due to increase
in image guided procedures and increase in aging population who usually opt minimally
invasive procedures.

Contrast agents based on the end-user market is segmented into hospitals, diagnostic &
ambulatory surgical centers and other which include academic and research institutes.

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Hospitals market accounted largest share in 2018 due to as there is a rise in demand for the
diagnosis and interventional treatment of diseases with CT or X-Ray, MRI and ultrasound
imaging procedures due to increase in incidence and prevalence of diseases and Diagnostic
& Ambulatory surgical centers is the fastest growing market due to increase in number of
diagnostic procedures related to musculoskeletal (arthroscopy, imaging of spine),
gastrointestinal (imaging of abdomen, GI tract) and obstetrics & gynecology
(hysterosalpingography).

The contrast agents global market based on geography is divided into North America,
Europe, Asia-Pacific and Rest of the world. North America region commanded the largest
revenue in 2018. Favorable reimbursement coverage and increase in incidence and
prevalence of diseases conditions due to change in lifestyle, obesity has led the market
growth in this region. However, Asia-Pacific region is the second leading market for contrast
agents and is expected to grow at highest CAGR from 2018 to 2025 due to increased
healthcare awareness, improved economic growth, large patient pool, and rising aged
population.

The innovations in contrast agents are taking place in area of packaging, the development of
bulk, multi-dose containers, and polymer containers. For instance, FDA approved Isovue
(iopamidol injection) Imaging Bulk Package (IBP) (developed by Bracco) which is a specific
combination multi-patient, multi-dose compliant contrast medium for point-of-care use in the
computed tomography (CT) suite. Increase in research activities for contrast which is
supported by funding from different institutes. For instance, Ferric Contrast Company
received $225,000 for phase I Small Business Technology Transfer (STTR) fund in 2017 in
for developing iron-based contrast agents for magnetic resonance imaging (MRI) which is an
alternative to the Gadolinium complexes that have traditionally been employed in
MRI. Likewise, Inlighta Biosciences LLC received a $2 million grant from the National
Cancer Institute in 2017 for development of an improved MRI contrast agent i.e. ProCA32 a
next-generation MRI contrast agents that could be utilized for early detection of primary and
metastasized liver cancers and the research is done through collaboration between Inlighta
Biosciences, Georgia State University, and Emory University. The funding is used in
validation of ProCA32 and used for toxicology a study which is required to support an
application to the FDA for human clinical trials.

The contrast agents/media market is consolidated and the top players in the market such as
GE Healthcare, Bracco Guerbet and Bayer control approximately XX% of the market as

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these companies have a strong distribution network acquiring small companies and
collaborations to reach the hospitals. For instance, Bracco and Shanghai pharmaceuticals
collaborated to provide innovative drugs in the field of oncology, infectious and CVDs in
China by making use of microbubble technology. Off-label use of contrast agents is a major
contributor of revenue growth.

Major players in the contrast agents global market are GE Company (GE Healthcare) (U.S.),
Bayer Group (Germany), Guerbet (France), Taejoon Pharm Co. Ltd., (South Korea), Beijing
Beilu Pharmaceuticals Company Limited (China), Bracco Group (Italy), Fujifilm Holding
Corporation (Japan), Sanochemia Pharmazeutika AG (Austria), Dongkook Lifescience
(Korea), Lantheus medical imaging (U.S.) and Fujipharma Co. Ltd (Japan).

Some of the emerging players in the contrast agents market are IMAX Diagnostic Imaging
Limited (Ireland), Zhejiang Starry Pharma (China), Graton Pharma (Pakistan), Nano-
Therapeutics (India), Unimark remedies (India), Harmony life sciences (India), Trivitron
Healthcare (India), Rege Imaging & Cinefilms private limited (India), Biem İlaç San. And
Tic. Inc. (Turkey), JB Chemicals and Pharmaceuticals Ltd (India), Jodas Expoim Pvt. Ltd
(India), Unijules Life Sciences Ltd (India), Magnus Health (India) and other companies.

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Reasons for buying this report:

 Contrast agents global market is expected to reach $6,879.0 million by 2025 at a
CAGR of 4.8%.
 Identification and analysis of the contrast agents market segments by molecule,
modality, applications, route of administration, imaging, end-users and geography.
 Revenue forecast of the contrast agents global market and strategic analysis of each
submarket with respect to segmental growth trends.
 Identification of major market trends, Porter's model and factors driving and
restraining contrast agents market growth.
 Revenue forecast of the contrast agents global market with respect to North America
(U.S. and Others), Europe (Germany, France, U.K. and others), Asia-Pacific (Japan,
China, Korea and others) and the Rest of the World (RoW) (Brazil, Rest of Latin
America and Middle East & Other) regions.
 Analysis of the opportunities for stakeholders by identifying the high-growth
segments of the market.
 Analysis of consumption of contrast agents for CT and MRI globally, regionally and
country wise.
 Number of procedures performed (CT, MRI) and average selling price (ASP) is
included in the report.
 Analysis of patent and supply chain of the contrast agents market.
 Identification of key technology developments and innovations driving the market.
 Profiles of major players in contrast agents market and analysis of their product
offerings, financial revenue, business strategies and SWOTs.
 Market share analysis of contrast agents global market and individual market share
analysis for X-Ray/CT, MRI and Ultrasound contrast agents global market.
 Established and emerging players (31 companies) and their product offerings.

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FIGURE 1

CONTRAST AGENTS GLOBAL MARKET SEGMENTATION

Contrast Agents Global Market

Molecule Modality Application RoA By Imaging

X-ray/CT CVD Intravascular Diagnostic

Iodine Gadolinium

Cancer Oral Interventional

MRI
Ionic Linear Macrocyclic
Rectal
Ultrasound GI
Monomer Ionic Ionic
Others
MSL
Dimer Non-Ionic
Non-Ionic
Neurology
Non-Ionic
Microbubble Nephrology
Monomer
Obs & Gyn
Others
Dimer
Urology

Others

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