SAFETY DATA SHEET

according to Regulation (EC) No. 1907/2006

Revision Date 30.06.2010

1. Identification of the substance/mixture and of the company/undertaking

Product Information
Catalogue No.: 100983
Product name: Ethanol absolute for analysis EMSURE® ACS,ISO,Reag. Ph Eur
Use of the Chemical production, Solvent, Pharmaceutical production and analysis
Substance/Mixture

Company: Merck KGaA * 64271 Darmstadt * Germany * Phone:+49 6151 72-0

Emergency telephone: Please contact the regional Merck representation in your country.
Responsible/issuing person: EQ-EPS * e-mail: prodsafe@merck.de

2. Hazards identification
GHS Classification
Flammable liquid, Category 2 H225: Highly flammable liquid and vapour.
EC Classification
F; R11
For the full text of the R-phrases mentioned in this Section, see Section 16.

3. Composition/information on ingredients
Formula C₂H₅OH C₂H₆O (Hill)
CAS-No. 64-17-5
Index-No. 603-002-00-5
EC-No. 200-578-6
Molar mass 46,07 g/mol

4. First aid measures

After inhalation: fresh air.

After skin contact: wash off with plenty of water. Remove contaminated clothing.
After eye contact: rinse out with plenty of water with the eyelid held wide open. Call in
ophthalmologist if necessary.
After swallowing: immediately make victim drink water (two glasses at the most). Consult doctor
in the event of any complaints.

5. Fire-fighting measures

Suitable extinguishing media

Carbon dioxide (CO2), Foam, Dry powder, Water
Specific hazards during fire fighting
Combustible material, Vapours are heavier than air and may spread along floors.
Forms explosive mixtures with air at ambient temperatures.
Pay attention to flashback.
Development of hazardous combustion gases or vapours possible in the event of fire.
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Page 1 of 8
Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 100983

Product name: Ethanol absolute for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Special protective equipment for fire-fighters

In the event of fire, wear self-contained breathing apparatus.
Further information
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Remove container from danger zone and cool with water.

6. Accidental release measures

Personal precautions
Avoid substance contact. Do not breathe vapours, aerosols. Ensure adequate ventilation.
Environmental precautions
Do not empty into drains. Explosive properties
Methods for cleaning up
Take up with liquid-absorbent material (e.g. Chemizorb® ). Forward for disposal. Clean up
affected area.

7. Handling and storage

Handling
Advice on safe handling
Observe label precautions.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition. Take precautionary
measures against static discharge.

Storage
Further information on storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and
sources of ignition.
Without limitations.

8. Exposure controls/personal protection

Personal protective equipment

Protective clothing should be selected specifically for the working place, depending on
concentration and quantity of the hazardous substances handled. The resistance of the
protective clothing to chemicals should be ascertained with the respective supplier.
Respiratory protection
required when vapours/aerosols are generated.
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds
Hand protection
full contact:
Glove material: butyl-rubber
Glove thickness: 0,7 mm
Break through time: > 480 min
splash contact:
Glove material: Nitrile rubber
Glove thickness: 0,40 mm

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
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Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 100983

Product name: Ethanol absolute for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Break through time: > 120 min

The protective gloves to be used must comply with the specifications of EC irective 89/686/EEC
and he resultant standard EN374, for example. KCL 898 Butoject® (full contact), KCL 730
Camatril® -Velours (splash contact).
The breakthrough times stated above were determined by KCL in laboratory tests acc. to
EN374 with samples of the recommended glove types.
This recommendation applies only to the product stated in the safety data sheet and supplied by
us as well as to the purpose specified by us. When dissolving in or mixing with other substances
and under conditions deviating from those stated in EN374 please contact the supplier of CE-
approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).
Eye protection
Safety glasses
Protective measures
Flame retardant antistatic protective clothing
Hygiene measures
Change contaminated clothing. Application of skin- protective barrier cream recommended.
Wash hands after working with substance.

9. Physical and chemical properties

Form liquid

Colour colourless

Odour alcohol-like

pH 7,0
at 10 g/l
20 °C

Viscosity, dynamic 1,2 mPa.s

at 20 °C

Melting point -114,5 °C

Boiling point/boiling range 78,3 °C

Ignition temperature 425 °C

DIN 51794

Flash point 12 °C
Method: c.c.

Oxidizing properties no data available

Flammability no data available

Lower explosion limit 3,5 %(V)

Upper explosion limit 15 %(V)

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
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Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 100983

Product name: Ethanol absolute for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Vapour pressure 59 hPa

at 20 °C

Relative vapour density 1,6

Density 0,790 - 0,793 g/cm3

at 20 °C

Solubility/qualitative no data available

Water solubility at 20 °C
completely miscible

Partition coefficient: n- log Pow: -0,31

octanol/water Method: (experimental)
(Lit.) No bioaccumulation is to be expected (log Pow <1).
Evaporation rate no data available

10. Stability and reactivity

Conditions to avoid
Warming. A range from approx. 15 Kelvin below the flash point is to be rated as critical.
Materials to avoid
Risk of explosion with:, Risk of ignition or formation of inflammable gases or vapors with:
Alkali metals, Alkaline earth metals, alkali oxides, Strong oxidizing agents, halogen-halogen
compounds, chromyl chloride, Ethylene oxide, Fluorine, perchlorates, potassium permanganate,
sulphuric acid, perchloric acid, permanganic acid, Oxides of phosphorus, Nitric acid, nitrogen
dioxide, uranium hexafluoride, hydrogen peroxide, chromium(VI) oxide
Hazardous decomposition products
no information available
Further information
unsuitable working materials:
various plastics, rubber
Vapours may form explosive mixture with air.

11. Toxicological information

Acute oral toxicity
LD50 rat
Dose: 6.200 mg/kg
(IUCLID)
Symptoms: Nausea, Vomiting
Acute inhalation toxicity
LC50 rat
Dose: 95,6 mg/l, 4 h
(RTECS)
Symptoms: slight mucosal irritations, absorption

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
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Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 100983

Product name: Ethanol absolute for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Skin irritation
rabbit
Result: No irritation
Method: OECD Test Guideline 404
Drying-out effect resulting in rough and chapped skin. Possible damages: Dermatitis
Eye irritation
rabbit
Result: No eye irritation
Method: OECD Test Guideline 405
Sensitisation
Sensitisation test (Magnusson and Kligman):
Result: negative
(IUCLID)
Genotoxicity in vitro
Ames test
Salmonella typhimurium
Result: negative
(National Toxicology Program)
Further information
Systemic effects:
euphoria
After absorption of large quantities:
Dizziness, inebriation, narcosis, respiratory paralysis
Further data:
Handle in accordance with good industrial hygiene and safety practice.

12. Ecological information

Ecotoxicity
Toxicity to fish
LC50
Species: Leuciscus idus (Golden orfe)
Dose: 8.140 mg/l
Exposure time: 48 h
(IUCLID)
Toxicity to daphnia and other aquatic invertebrates.
EC5
Species: E.sulcatum
Dose: 65 mg/l
Exposure time: 72 h
(maximum permissible toxic concentration) (Lit.)
EC50
Species: Daphnia magna (Water flea)
Dose: 9.268 - 14.221 mg/l
Exposure time: 48 h
(IUCLID)

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
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Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 100983

Product name: Ethanol absolute for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Toxicity to algae
IC5
Species: Scenedesmus quadricauda (Green algae)
Dose: 5.000 mg/l
Exposure time: 7 d
(maximum permissible toxic concentration) (Lit.)
Toxicity to bacteria
EC5
Species: Pseudomonas putida
Dose: 6.500 mg/l
Exposure time: 16 h
(maximum permissible toxic concentration) (IUCLID)
Persistence and degradability
Biodegradability
Result: Readily biodegradable.
94 %
Method: OECD Test Guideline 301E
Biochemical Oxygen Demand (BOD)
930 - 1.670 mg/g (5 d)
(Lit.)
Chemical Oxygen Demand (COD)
1.990 mg/g
(IUCLID)
Theoretical oxygen demand (ThOD)
2.100 mg/g
(Lit.)
Ratio BOD/ThBOD BOD5 74 %
(IUCLID)
Ratio COD/ThBOD 90 %
(Lit.)
Partition coefficient: n-octanol/water
log Pow: -0,31
Method: (experimental)
(Lit.) No bioaccumulation is to be expected (log Pow <1).
Additional ecological information
Do not allow to enter waters, waste water, or soil!

13. Disposal considerations

Product
Chemicals must be disposed of in compliance with the respective national regulations. Under
www.retrologistik.de you will find country- and substance-specific information as well as contact
partners.
Packaging
Merck product packaging must be disposed of in compliance with the country-specific
regulations or must be passed to a packaging return system. Under www.retrologistik.de you will
find special information on the respective national conditions as well as contact partners.

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
Page 6 of 8
Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 100983

Product name: Ethanol absolute for analysis EMSURE® ACS,ISO,Reag. Ph Eur

14. Transport information

ADR/RID
UN 1170 ETHANOL, 3, II
IATA
UN 1170 ETHANOL, 3, II
IMDG
UN 1170 ETHANOL, 3, II
EmS F-E S-D
The transport regulations re cited according to international regulations and in the form applicable
in Germany. Possible national deviations in other countries are not considered.

15. Regulatory information

GHS-Labelling
Hazard pictograms

Signal word
Danger

Hazard statements
H225: Highly flammable liquid and vapour.

Precautionary statements
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking.

Reduced labelling (≤125 ml)

Hazard pictograms

Signal word
Danger

Index-No. 603-002-00-5
Labelling according to EC Directives
Symbol(s): F Highly flammable

R-phrase(s): 11 Highly flammable.

S-phrase(s): 7-16 Keep container tightly closed. Keep away from sources
of ignition - No smoking.
EC-No. 200-578-6 EC Label

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
Page 7 of 8
Safety Data Sheet
according to Regulation (EC) No. 1907/2006

Catalogue No.: 100983

Product name: Ethanol absolute for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Reduced labelling (≤125 ml)

Symbol(s): F Highly flammable

National legislation
Storage class VCI: 3 Flammable Liquids
Major Accident Hazard 96/82/EC Update: 2003
Legislation: Highly flammable
7b
Quantity 1: 5.000 t
Quantity 2: 50.000 t
Other regulations: Take note of Dir 94/33/EC on the protection of young people at
work.

16. Other information

Full text of R-phrases referred to under sections 2 and 3
R11 Highly flammable.

Regional representation: This information is given on the authorised Safety Data Sheet for
your country.

The information contained herein is based on the present state of our knowledge. It characterizes the product with
regard to the appropriate safety precautions. It does not represent a guarantee of the properties of the product.

The Safety Data Sheets for catalog items are also available at www.merck-chemicals.com
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