05/09/2018 Therapeutic Assessment of Vulvar Squamous Intraepithelial Lesions with CO2 Laser Vaporization in Immunosuppressed Patients

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Abstract
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RIBALTA, Julisa Chamorro Lascasas; MATEUSSI, Mariana Vendramin and Google Scholar H5M5 (2017)
SPECK, Neila Maria de Góis. Therapeutic Assessment of Vulvar
Squamous Intraepithelial Lesions with CO2 Laser Vaporization in Article
Immunosuppressed Patients. Rev. Bras. Ginecol. Obstet. [online]. 2018,
vol.40, n.1, pp.26-31. ISSN 0100-7203. http://dx.doi.org/10.1055/s-0037- English (pdf)
1618573.
English (epdf)

Objective Article in xml format

A vulvar squamous intraepithelial lesion is deemed to be a preceding lesion Article references

to vulvar cancer, especially in women aged under 40 years, holders of an How to cite this article
acquired or idiopathic immunosuppression. Several treatments have been
used to treat these lesions. One of the aesthetically acceptable therapeutic SciELO Analytics
methods is the CO2 laser vaporization.
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Methods Indicators
In a transversal study, 46 records of immunosuppressed women bearing a Related links
vulvar low grade and/or high grade squamous intraepithelial lesion were
selected out of the retrospective analysis, computing age, date of record, Share
date of vulvar lesion treatment with CO2 laser, the time elapsed between
More
the first and the last visit (in months), the number of visits, the presence or
absence of condylomatous lesions in other female lower genital tract sites More
and whether or not recurrences and persistence of intraepithelial lesions
have been noticed during the follow-up.
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Results

Patients bearing vulvar high-grade squamous intraepithelial lesion and immunosuppressed (serumpositive
forhumanimmunodeficiency virus [HIV] or with solid organs transplantation) have shown a higher level of
persistence of lesions and a higher chance of having other areas of the female lower genital tract involved.

Conclusion

While the CO2 laser vaporization is the most conservative method for the treatment of vulvar high-grade
intraepithelial lesions, it is far frombeing the ideal method, dueto the intrinsic infection features considered. The
possibility of persistence, recurrences and spontaneous limited regression indicates that a closer surveillance in
the long-term treated cases should be considered, in special for immunosuppressed patients.

Keywords : vulvar intraepithelial neoplasia; usual vulvar intraepithelial neoplasia; vulvar high-grade squamous
intraepithelial lesion; CO2 laser; laser therapy.

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