VII.

PATHOPHYSIOLOGY

Nephrotic syndrome - is a kidney disorder that causes your body to excrete too much protein in your
urine.

Risk Factors
MODIFIABLE NON-MODIFIABLE
 Lifestyle
 Age
 Previous Medications  Gender
 Environment  Heredity
 Past Medical History

Etiology: Damage to glomerular capillary membrane

Loss of plasma protein (albumin)

Stimulates synthesis of lipoproteins

Hypoalbuminemia

Hyperlipidemia Decreased oncotic pressure

Fluid moves from vascular space

to extracellular fluid

Activation of renin-angiotensin system

Sodium retention

Edema