CELL CYCLE N CHROMOSOME

1. DNA replication occurs in 9. Daughter cells are formed as a result of meiosis are not similar to that of
parent cell because
a) S phase b) G phase c) G2 phase d) M phase
a) Meiosis is completed in two stages b) Prophase is longest phase
2. The pairing of homologous chromosomes
c) Nucleus size increases in daughter cells
a) Tetrads b) Crossing over c) Synapsis d) Terminalisation
d) Crossing over takes place and chromosome number is halved
3. Which aspect of mitosis is affected by colchicine in inducing polyploidy?
10. During meiosis chiasmata are observed at
a) DNA duplication b) Spindle formation
a) Pachytene b) Diplotene c) Leptotene d) Diakinesis
c) Cell plate formation d) Chromosome doubling
11. Number of mitotic divisions required to produce 128 cells from a single cell
4. Pairing of homologous chromosomes can be seen during is
a) Zygotene b) leptotene c) Diplotene d) Pachytene a) 7 b) 8 c) 16 d) 32
5. The cell cycle of a germinal cell has 12. During which stage of prophase I the crossing over takes place?
a) two successive mitotic divisions b) two successive reduction divisions a) Pachytene b) Leptotene c) Zygotene d) Diplotene
c) very short prophase in first division 13. The spindle forms in the
d) one reduction division followed by one mitotic division a) G1 phase b) G2 phase c) M phase d) S phase
6. During cell division, sometimes there will be failure of separation of sister 14. Which phase of mitosis is associated with chromosomes aligned at the center
chromatids. This event is called of the cell and centromeres divide?
a) interference b) coincidence c) fusion d) Non disjunction a) anaphase b) interphase c) metaphase d) prophase
7. During metaphase mitosis chromosomes 15. The event(s) which does not occur during interphase, is/are
a) undergo coiling b) Move towards the poles a) Chromatin condenses b)Protein Synthesis
c) Line up at the equatord) Break and disintegrate c) Organelles replication d) DNA replication
8. In how many cells the meiotic division has taken place, if the total number of 16. At which of the following check point, mitosis is controlled?
spermatids produced are 32?
a) G1 b)G2 c)M d) S
a) 16 b) 8 c) 32 d) 4
17. Sequences that correctly describes the cell cycle is
 a) Anaphase b) Interphase c) Metaphase d) Prophase

a) -> G1-> G2 -> S -> mitosis -> cytokinesis -> 23. The phase of mitosis which is associated with the formation of the nuclear
envelope, is
b) -> S -> G2 -> mitosis -> cytokinesis -> G1 ->
a) prophase b) metaphase c) anaphase d) telophase
c) -> G1 ->S -> G2 -> cytokinesis -> mitosis ->
24. At the __________ checkpoint, cell growth is controlled.
d) ->cytokinesis-> mitosis -> G1 -> S -> G2 ->
a) C b) G1 c) G2 d) S
18. The term, not related to mitosis is
25. A nuclear envelope forms around each set of sister chromatids in
a) gametes b) chromosomes
a) prophase b) metaphase c) anaphase d) telophase
c) DNA replication d) somatic cells
26. Which of the following plays a substantial role in linking together sister
19. A centromere is chromatids immediately after replication?
a) another name for kinetochore b) the structure to which microtubules attach a) Cohesins b) Condensins c) Histones d) Topoisomerases
c) a constriction on a chromosome bound to a disk d) all of the above 27. 5. Chromatin is composed of
20. Which of the following statements about mitosis is incorrect? a) DNA b) DNA and proteins c) DNA, RNA and proteins d) None
a) The daughter nuclei are genetically identical to the parent nucleus 28. Which of the following histones bind to linker DNA?
b) Chromosomes separate during anaphase due to the interaction of polar a) H1 b) H2A c) H2B d) H3
microtubules from opposite poles pushing against each other
29. Which of the following has beads on a string structure?
c) Chromosomes separate during anaphase when the kinetochore microtubules
shorten as they depolymerize a) Chromosomes b) Chromatin c) Nucleosomes d) Heterochromatin

d) Chromosomes move to the metaphase plate using motor proteins, a kind of 30. Cellular DNA is uncondensed throughout
kinesin, attached to spindle fibers
a) Prophase b) Interphase c) Telophase d) Anaphase
21. Which of the following is not a part of a human chromosome in any phase?
31. Bacteria have single chromosome, i.e. they are
a) Centriole b)Histone c) Nucleosome d) Centromere
a) diploid b) haploid c) monoid d) tetroid
22. In which phase, each chromosome replicates to produce two sister
chromatids? 32. There are 48 chromosomes in a cell of a
a) chimpanzee b) human being c) drosophila d) monkey

33. Chromosome doubling in every generation reproducing sexually is prevented

by

a) meiosis b) reduction division c) both A and B d)mitosis

34. The haploid set of the chromosomes is called as

a) proteome b) genomics c) genome d) genes

35. The term ‘chromosome (chrom=color, soma=body)’ was coined by

a) W. Flemming b) W.Roux c) Waldeyer d) Sutton

36. Which of the following has the largest number of chromosome?

a) Haplopappus gracilis b) Ophioglossum reticulatum

c) Pisum sativum d) Giant redwood tree

37. The size of chromosome is measured during

a) prophase b) metaphase c) anaphase d) all of these

38. A chromosome with a very short arm and a very long arm

is termed as

a) Telocentric b) Acrocentric c) Metacentric d) Sub-metacentric

39. A functional chromosome has

a) a centromere b) a telomere c) an origin of replication d) all of these

40. The diagrammatic representation of karyotype (morphological representation

of chromosomes) of a species is called

a) Idiogram b) cladogram c) ecogram d) chromogram