Cerebrospinal .

C
O
M

fluid
A
M
A
N
Y
D
U
T
S
 Introduction
• CSF is clear, colorless and transparent
M
• Circulates through cavity of the:
O
.C
– Brain A
– Subarachnoid space AM
N
– Central canal of spinal
Y cord
D
• Part of Extracellular
T
U fluid (ECF)
S
 Properties
• Volume : approximately 150 mL
M
• Rate of formation: approximately
O 0.3 mL/min
.C
• Specific gravity : 1.005 A
M
• Reaction : Alkaline
N
A
Y
D
U
T
S
 Composition
Cerebrospinal Fluid
Water - 99.13% Solids - 0.87%
M
O
.C
A
Organic substances Inorganic substances
M
1.Proteins A 1.Sodium
N
2.Amino acids Y 2.Calcium
3.Sugar D 3.Potassium
U
4.Cholesterol T 4.Magnesium
S
5.Urea 5.Chlorides
6.Uric acid 6.Phosphate
7.Creatinine 7.Bicarbonates
8.Lactic acid 8.Sulfates
Lymphocytes in CSF : 6/ cu mm
Studynama’s BDS Community is one of India’s Largest Community of Dental Students. About
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Continued…
• As CSF is part of ECF therefore it contain more
amount of Sodium than Potassium. O
M

.C
• Contains some lymphocytes. A
M
• CSF secreted by ventricles
A does not contain
N
any cell. Y
D
• The lymphocytesT
U are added when it flows in
S
the spinal cord.
 Formation of CSF
• Site of formation
M
– Formed by the choroid plexus situated
O within the
ventricles. .C
A
M
A
– The choroid plexus are tuft
N of capillary projections present
Y
inside ventricles andDcovered by:
• Pia mater TU
• EpendymalScovering.
Continued...
Mechanism of formation
M
• Formed by process of secretion. O
.C
A
M
• Does not involve ultrafiltration
A or dialysis.
N
Y
D
• Uses energy. T
U
S

• Active transport mechanism is involved in secretion.

 Circulation of CSF
Formation of CSF in lateral ventricles

Foramen of Monro

Third ventricle M
O
Aqueductus Sylvius .C
A
Fourth ventricle M
A
N
Foramen of magendie
Y and foramen of
Luschka D
Umagna and Cisterna lateralis
Cisterna
T
S
Subarachnoid spaces

To the spinal cord To cerebral hemispheres

 M
O
.C
A
M
A
N
Y
D
U
T
S
Studynama’s BDS Community is one of India’s Largest Community of Dental Students. About
19,232 Indian Dental Course students are members of this community and share FREE study
material, cases, projects, exam papers etc. to enable each other to do well in their semester exams.

Links to Popular Study Material for BDS (Dental) students:

 Orthodontic Fixed Appliances - BDS Lecture Notes PDF Download
 Amalgam Restoration - BDS Lecture Notes PDF Download
 COMPLEX NON-SKELETAL PROBLEMS IN PREADOLESCENT CHILDREN - BDS Lecture Notes
 Anatomy of Scalp - BDS Lecture Notes PDF Download
 Cerebrospinal Fluid (CSF) - BDS Lecture Notes PDF Download
 Cementum - BDS Lecture Notes PDF Download
 Recent Advances in Instrumentation Techniques - BDS Lecture Notes PDF Download
 Ameloblastoma - BDS Lecture Notes PDF Download
 Prevention of Odontogenic Infection - Principles of Management - BDS Lecture Notes
 Therapeutic Dentistry Histology of Teeth Dental Charting - BDS Lecture Notes PDF Download
 Maxillofacial Trauma and Management - BDS Lecture Notes PDF
 Technical Endodontics - BDS Lecture Notes PDF Download
And 698 more free downloads for Dental Students.
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 Absorption of CSF
• Mostly absorbed by the Arachnoid villi into
Dural sinuses and Spinal veins. M
O
.C
A
• Small amount is absorbed M along the
A
perineural spaces intoN cervical lymphatics and
Y
in to the perivascular
D spaces.
U
T
S
• Normally, 500 mL of CSF is formed everyday
and equal amount is absorbed.
 Pressure exerted by CSF
• Varies in different position:
M
Lateral recumbent position = 10-18
O cm of H2O
.C
Lying position A= 13 cm of H2O
Sitting position A
M = 30 cm of H2O

N
Coughing and crying Yincreases the pressure by
D
decreasing the absorption.
U
T
S
Compression of internal jugular vein also raises
the CSF pressure.
 Function of CSF
• Protective Function:
M
– Acts as buffer O
.C
– Protects the brain from shock
A
M
A
N
• If brain receives severe
D
Y blow , countercoup
injury may takeT place.
U
S
Continued…
• Medium of Exchange
M
• CSF is the medium through which
C
O substances
.
like : A
M
– Nutritive substances A
N
– Waste materials Y
D
U
T between blood and brain tissues.
are exchanged
S
Studynama’s BDS Community is one of India’s Largest Community of Dental Students. About
19,232 Indian Dental Course students are members of this community and share FREE study
material, cases, projects, exam papers etc. to enable each other to do well in their semester exams.

Links to Popular Study Material for BDS (Dental) students:

 Orthodontic Fixed Appliances - BDS Lecture Notes PDF Download
 Amalgam Restoration - BDS Lecture Notes PDF Download
 COMPLEX NON-SKELETAL PROBLEMS IN PREADOLESCENT CHILDREN - BDS Lecture Notes
 Anatomy of Scalp - BDS Lecture Notes PDF Download
 Cerebrospinal Fluid (CSF) - BDS Lecture Notes PDF Download
 Cementum - BDS Lecture Notes PDF Download
 Recent Advances in Instrumentation Techniques - BDS Lecture Notes PDF Download
 Ameloblastoma - BDS Lecture Notes PDF Download
 Prevention of Odontogenic Infection - Principles of Management - BDS Lecture Notes
 Therapeutic Dentistry Histology of Teeth Dental Charting - BDS Lecture Notes PDF Download
 Maxillofacial Trauma and Management - BDS Lecture Notes PDF
 Technical Endodontics - BDS Lecture Notes PDF Download
And 698 more free downloads for Dental Students.
Other Popular Links for Law Study Material:
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 BDS Lecture Notes, eBooks, Guides & Handouts FREE PDF Download
 BDS University Previous Year Exam Question Papers & Solutions FREE PDF Download
 CSF disorders
• Hydrocephalus
M
– Abnormal accumulation of CSF O in the skull with
. C
enlargement of head. A
M
A
N
• 2 types of Hydrocephalus
Y
D
1. non-communicating
T
U
S
2. communicating
Continued…
Non-communicating Hydrocephalus or
Internal Hydrocephalus M
Due to the obstruction of any of theOforamen through
.C
which CSF escapes results in dilation
A of ventricular
cavity. M
A
N
Communicating Hydrocephalus
D
Y
or External
HydrocephalusTU
Due to blockageSof Arachnoid villi.
Continued…
Symptoms of Hydrocephalus:
M
O
Headache .C
A
Vomiting M
Atrophy of brain NA
Y
Mental weaknessD
U
ConvulsionsT
S
 M
O
.C
A
M
A
N
Y
D
U
T
S
 M
O
.C
A
M
A
N
Y
D
U
T
S