COLLEGE OF MEDICAL LABORATORY SCIENCE

City of Dasmarinas, Cavite, Philippines

Cavite: (63) (46) 481-8000 Manila: (63) (2) 988 3100

www.dlshsi.edu.ph

SEMINAR II

ASSESSMENT EXAMINATION RATIONALIZATION

IMUNOHEMATOLOGY
2nd SEMESTER A. Y. 2017 – 2018

1. What type of serological testing does the blood bank technologist perform when determining the blood
group of a patient?
Answer: Phenotyping

2. If the frequency of gene Y is 0.4 and the frequency of gene Z is 0.5, one would expect that they should
occur together 0.2 (20%) of the time. In actuality, they are found together 32% of the time. This is an
example of:
Answer: Linkage disequilibrium

3. In the Hardy–Weinberg formula, p2 represents:

____________________________________________________

4. An individual’s red blood cells give the following reactions with Rh antisera:
Anti –D Anti-C Anti-E Anti-c Anti-e
4+ 3+ 0 3+ 3+
The individual’s most probable genotype is:
Answer: DCe/dce

5. In an emergency situation, Rh-negative red cells are transfused into an Rh-positive person of the
genotype CDe/CDe. The first antibody most likely to develop is:
__________________________________________________

6. Refer to the following data:

Anti –D Anti-C Anti-E Anti-c Anti-e
+ + + + +
Given the reactions above, which is the most probable genotype?
Answer: R1R2

7. Which of the following phenotypes will react with anti-f?

Answer: rr

8. What is the probable genotype of a patient which has produced an anti-c?

Answer: r’ ry

9. What is the unit to be given to patient with anti-e?

Answer: r” ry

10. Reaction of RBCs with the following antisera:

Anti –D Anti-C Anti-E Anti-c Anti-e
+ + - - +
What is the probable genotype of the patient?
Answer: R1 R1

11. Patient: R1R1 Donor: R2 R2

What antibodies are produced by an R1R1 patient if exposed to R2 R2 donor unit?
__________________________________________________

12. Which of the following blood groups reacts least strongly with an anti-H produced in an A1B
individual?
Answer: Group A1

13. The ABO serum grouping may not be valid when: The patient has hypogammaglobulinemia, IgM
alloantibodies are present, Cold autoantibodies are present

14. The red blood cells used for screening patient’s serum for unexpected antibodies should be of what
group? _____

15. If a group AB is mated with a group O, the following genotype will result:
________________________________

16. The enzyme responsible for conferring H activity on the red cell membrane is
______________________

17. Criteria determining Rh immune globulin eligibility include:

Answer: Mother has not been previously immunized to the D antigen

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 COLLEGE OF MEDICAL LABORATORY SCIENCE
City of Dasmarinas, Cavite, Philippines

Cavite: (63) (46) 481-8000 Manila: (63) (2) 988 3100

www.dlshsi.edu.ph
18. What is the correct process in preparing multi-donor platelet concentrates?
________________________________________________________________________________
__________
19. A packed RBC unit collected in CPDA-1 blood bag and separated on September 29, 2017 is to be
given to a immunocompromised recipient. The blood unit was irradiated on the same day of the collection
as requested by the patient’s attending physician. What is the last day that the unit can be transfused?
________________________________________________________________________________
_________

20. What is the absolute leukocyte count required for leukoreduced random donor platelet concentrates?
________

21. What is the difference in components between deglycerolized RBCs and frozen RBCs?

22. What is the general composition of PPF?

Answer: 83% albumin and 17% globulins

23. Which crystalloid solution is most preferred as a blood volume expander?

_______________________________

24. How long is the shelf life of a thawed cryoprecipitated

AHF?___________________________________________

25. Which of the following is not true regarding donor deferrals?

a. Hepatitis booster shot - deferred for 2 weeks
b. Tattoo - deferred for 12 months
c. Recent alcohol intake - deferred for 12 hours
d. Malarial infection - deferred for 3 years

26. A 56-year-old man; 168 lb; hematocrit, 44%; took aspirin 4 hours ago for arthritis pain. Accept or
reject?

27. A 65-year-old female; has instructions from physician to donate for her upcoming surgery; had
syphilis and was treated 40 years ago; hematocrit, 37%; temperature, 36°C. Accept or reject?

28. A 19-year-old female college student; last menstrual period was 2 weeks prior; taking isotretinoin
(Accutane) for acne. Accept or reject?

29. With the addition of sample tubes, donors who weigh 50 kg may donate the following maximum
amount of whole blood: ________________________

30. The most frequent transfusion-associated disease complication of blood transfusion is:
_____________________

31. A double dose of RhIg can neutralize how many mL of whole blood cells?
________________________________

32. Most common cause of transfusion reactions: _________________________________________

33. The only transfusion reaction allowed to continue transfusion:

____________________________________

34. The most commonly used anticoagulant in apheresis:

_______________________________________________

35. The “H” in HEMPAS stands for:

_______________________________________________________________

36. The most common bacterial contaminant for platelet concentrate:

_____________________________________

37. A type B individual who has a sese gene will have _________________________ on their secretions

38. Rh Immunoglobulin is given during:

_________________________________________________________

39. Deglycerolization is a process of removing glycerol by washing red cells in a

______________________________

40. Which plateletpheresis product should be irradiated?

a. autologous unit collected prior to surgery
b. random stock unit going to a patient with DIC
c. a directed donation given by a mother for a son
d. a directed donation given by an unrelated family friend

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 COLLEGE OF MEDICAL LABORATORY SCIENCE
City of Dasmarinas, Cavite, Philippines

Cavite: (63) (46) 481-8000 Manila: (63) (2) 988 3100

www.dlshsi.edu.ph

41. Hydroxyethyl starch (HES) is a rouleaux-promoting agent used to:

______________________________________

42. Platelets prepared in polyolefin type container, stored at 22-24 C in 50 mL of plasma, and gently
agitated can be used for up to ____________ days

43. Which of the following blood components must be prepared within 8 hours after phlebotomy?
______________

44. Rejuvenation of a unit of Red Blood Cells is a method used to:

_______________________________________

45. The usual dose of platelet concentrate for an adult in a transfusion is ________ units.

46. “O” secretor person would demonstrate what substance(s) in his saliva:
_______________________________

47. In order for transfusion to be successful, how much (%) of the transfused red cells must at least
survive in the recipient’s circulation? __________________________________________________

48. Rouleaux formation does NOT affect: __________________________________________________

49. Which of the following blood group systems offers the highest exclusion probability in paternity
testing:
_______________________________________________________________

50. A unit of whole blood produces an increase in hematocrit in an adult recipient of: _______________

51. The ZZAP method is used in ________________________________________________________

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