PHRM 841: Veterinary Pharmacy and Compounding Lab

Name:
Week of April 23-27
Instructor Initials & Score ____ /30 points Desk # Section #

Activity 1: Veterinary Resources

A. Examine your source, talk within your group. Pick a spokesperson or two to present what you
have found for your source
B. Present to the lab, and take notes on other sources
C. Regroup and compare/contrast the sources to determine why you think yours was unique or
specifically useful
D. Pick another student to quickly state why your source is unique in 20 seconds or less!

Each group should look at the following parameters for the assigned resource:
1. How are they available (online, paperback, both)
2. How are they organized (by drug, by disease, etc.)
3. How recent is the information (i.e. how reliable)
4. Topics that are covered (mechanism of action, uses, side effects, approved/extralabel uses, etc.)
5. Ease of use
6. Any unique features?

- Plumb’s Veterinary Drugs (Table 1)

- Saunders Handbook of Veterinary Drugs (Table 2)

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 Name: __________________________

- The Green Book (Tables 3 & 4)

- Merck Veterinary Manual (Tables 5 & 6)

- FARAD (Tables 7 & 8)

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Activity 2: Dose Comparisons

Using Lexicomp/Micromedex/Facts & Comparisons and Plumb’s compare the doses for humans vs.
dogs for the following medications. Also give a few counseling points for human patients, we will go
over counseling for dogs together.

Dosing in Humans Dosing in Dogs

Cephalexin
Counseling Points:

Fluoxetine
Counseling Points:

Levetiracetam
Counseling Points:

Levothyroxine
Counseling Points:

Mirtazapine
Counseling Points:

Phenobarbital
Counseling Points:

Tramadol
Counseling Points:

Trazodone
Counseling Points:

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 Name: __________________________

Activity 3: Toxins
Which of the products available on your tables are toxic to dogs?

Acetaminophen Carrots Cheese

Chocolate Diphenhydramine Grapes

Gum Ibuprofen Onion

Orange Peanut Butter Penny

Sweet Potato

After identifying the toxic substances, determine their toxic effect in the dog.

1.

2.

3.

4.

5.

6.

7.

8.

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Activity 4: Compounding Flavors

What flavor do you think these are?
1.

2.

3.

4.

5.

Which of the above flavors do you think we use for the following species – may be used more than once.
- Cats

- Dogs

- Birds

- Horses

What common flavors should not be used in animal compounds?

1.

2.

3.

Why should these flavors not be used?

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Activity 5: Compounding
Formula for Chicken Broth Animal Treats

Base, PCCA Animal Treat-Chicken: 0.525 g per treat

Xanthan Gum: 0.075 g per treat
Flavor, Chicken Broth, Spray Dried: 0.375 g per treat
Glycerin: 0.35 mL per treat
Dispensing Blister Pack 1 cavity per treat

Each student will make 6 treats. It is recommended that calculations should be made for an extra
10% to allow for any loss. For example if you need 30 treats, it’s recommended that you calculate
for 33 treats – you will have a little left over product at the end.

1. Calculate the amounts needed for your compound. Show calculations below.
2. Weigh out your ingredients using the provided balance.
3. Using the principles of geometric dilution, mix the Animal Treat-Chicken Base, Chicken Broth
Flavor, and Xanthan Gum together with trituration in a mortar and pestle.
4. Add the Glycerin to step 3 and mix until all the powder is moist and a dough is formed. Spray
Pam onto gloved hands. Knead and form the dough into a uniform mass.
5. Pack your product into the mold (blister packs) and scrape off any excess product.
6. Seal with the adhesive labels.

Show your calculations below for determining ingredient amounts needed.