Paper I-IV, Techniques, previous year

question papers(2001-2017) – Paper

wise distribution
1. PAPER I - Role of immunofluorescence in skin biopsy (5x2).
2. Quality control in routine H & E Staining (5).
3. Role of Imprint cytology in diagnosis (5).
4. Stains of amyloid (5,2)
5. Fixatives in cytology (5)
6. Reactive mesothelial cell vs malignant epithelial cell in fluid cytology (2)
7. Use of elastic stains in hitopathology (2)
8. Bouin s fixative (2)
9. TRAP test (2)
10. Synovial biopsy (5x2)
11. Special stains for amoeba (2)
12. Special stains for copper (2)
13. Mercurial fixatives (2)
14. Digital photography in pathology (5)
15. Internet resources in pathology (5)
16. Squash in CNS tumours (5x2)
17. Museum mounting fluid (2)
18. Formalin pigment (2)
19. Argentaffin reaction (2)
20. Perinatal autopsy (5x2)
21. Biological waste disposal and its significance. (5x3)
22. Ethical aspects in pathology. (5)
23. Ideal fixative for bone marrow biopsy (2)
24. Stain for HbsAg (2)
25. Role of cytology in ovarian carcinoma (5)
26. Effects of drying on a Papanicolaou smear (2)
27. Fine needle aspiration cytology findings in Hashimoto’s thyroiditis(2)
28. Metachromasia (2)
29. Staining methods to detect fungi in tissues (5).
30. Uses and limitations of electron microscopy (5)
31. Histological patterns oftesticular biopsies in infertile men (5)
32. Nerve biopsy (5)
33. Liver biopsy (2)
34. How is the muscle to be biopsied selected?(2); Muscle biopsy(5)
35. Discuss usefulness of radiographs in fetal, perinatal and pediatric autopsies.(5)
36. Discuss briefly about key to successful macrophotography(5)
37. What is chromaffin reaction? Mention its application(2)
38. Limitation in molecular diagnostic techniques.(2)
39. What is blocking of tissue and which paraffin wax is ideal for blocking tissue?(2)
40. Mention various mesothelial cell morphology in Pleural / peritoneal fluid cytology(2)
41. Application of Immunomarkers by algorithmic approach to diagnose unclassified tumors.(5)
42. Electrophoresis(5)
43. Polymerase chain reaction – application in diagnostic pathology(5)
44. Role of immunoflorescence in understanding glomerulonephritis.(6)
45. Histopathologist and Law(6)
46. Direct DNA diagnosis(6)
47. Gene therapy(6)
48. Approach to autopsy in AIDS(6)
49. Isoenzymes(6)
50. Quality control in histopathology(5,10)
51. Accreditation and reaccreditation of pathologists
52. Autopsy findings in a case of Cerebrovascular accident.(5)
53. FISH(5)
54. Laboratory investigations in male infertility(5)
55. Autopsy in maternal death (5)
56. Quality control in cytology (5)
57. Cytokeratin immunoprofiles in diagnosis (5)
58. Tissue arrays – construction and applications (5)
59. Applications of immunofluorescence(5x2)
60. Fixatives (5)
61. Mucins (5)
62. Melanin and its demonstration (5)
63. Haematoxylin in surgical pathology practice (5)
64. Disposal of laboratory wastes (10)
65. Applications of in situ hybridization (10)
66. Urine microscopy(10)
67. Endomyocardial biopsy (5)
68. Describe the various DNA recombinant techniques and their diagnostic application in
histopathology (10)
69. PAPER II - Chorionic villus sampling (2)
70. Stains for fungi(5)
71. Recent advances in karyotyping techniques
72. Special stains for amyloid (2)
73. Stains for fibrin (2)
74. Principles of FISH (5); TISH(5)
75. Discuss role of Cytokeratin immune staining profiles in diagnostic anatomical
pathology.(10,5)
76. Applications of PCR (5)
77. Biomedical waste management (5)
78. Mucin histochemistry(5x2)
79. Frozen section (5)
80. Limitations of FNAC (5)
81. Role of immunohistochemistry in histopathology (20)
82. Gene therapy (5)
83. Discuss the various methods used in the post natal diagnosis of genetic diseases(10)
84. Discuss tumour cell proliferation markers and their significance (10)
85. Fluorescent miscroscopy and its use in diagnosis (10)
86. Discuss clinical utility and methodology of telepathology(10)
87. Electron microscopy (5)
88. Automation in pathology(5)
89. DNA finger printing and its utility(5)
90. Molecular diagnostic techniques(10)
91. Paper III - Partial autopsy (2)
92. Role of testicular biopsy in male infertility(5)
93. Synovial biopsy(5)
94. Discuss the role of squash preparations in neuropathology.(10)
95. Enzymes used in muscle biopsy(2)
96. Endomyocardial biopy (5x4)
97. IF in glomerulonephritis(5)
98. Neutral mucin
99. CSF in pyogenic meningitis(2)
100. Discuss the role of immunohistochemistry in CNS neoplasms(10)
101. Mucin histochemistry in Gastro intestinal lesions.(5)
102. Describe various dissection techniques of heart and discuss clinico pathologic
autopsy findings in valvular disease of heart.(5)
103. Discuss importance of immunohistochemistry and other markers in soft tissue
sarcomas.(10)
104. Role of IHC in round cell sarcomas(5)
105. Role of IF in acute glomerulonephritis(5)
106. In situ hybridisation-its utility as a diagnostic tool(5)
107. Bone marrow transplantation(5)
108. Role of EM in renal diseases(10)
109. Paper IV - Quality control in hematology laboratory.(5)
110. Usage of Cryostat in pathology.(2)
111. Semen Analysis.(2)
112. Enumerate uses of silver stains in Histopathology.(2)
113. Discuss Automation in Histopathology.(10)
114. Photography of gross specimens.(5)
115. LJ chart(5)
116. Sample rejection criteria(5)
117. External quality assurance(5)
118. Phase contrast microscopy(2)
119. Reticulocyte count(2)
120. Coomb’s test(2)
121. What are the molecular diagnostic methods used in the pathology lab? Discuss the
principles and applications of flow cytometry(10)
122. Decalcifying agents in histopathology(2)
123. Role of FNAC in evaluation of soft tissue neoplasms.(10)
124. Bethesda system of reporting for FNAC thyroid.(5)
125. FISH(5)
126. Internal quality control(5)
127. EQAS(2)
128. Cytospin (5)
129. Hb electrophoresis(5)
130. Telepathology (5)
131. WHO protocol for semen analysis(5)
132. Discuss in detail about quality control in the pathology laboratory(10)
133. Digital photography in histopathology(5)
134. Critical alert values(2)
135. Vacutainers(2)
136. What are high density tissue microarray? Discuss the mechanics and design of
microarray and its applications.(10)
137. HIFs (2)
138. Name the IHC marker used to differentiate reactive condition is from neoplasm(2)
139. What is external quality assurance(2)
140. Name stains for Melanin(2)
141. What do you understand by gene expression profile?(2)
142. Carnoys fixative(2)
143. Types of nerve biopsy preparations.(2)
144. Role of IHC in diagnosing tubal metaplasia vs endometriosis.(5)
145. Principle of fluorescence in situ hybridisation(2)
146. Cytocentrifuge(2)
147. Electrophoresis(5)
148. What are the battery of stains performed on frozen and fixed muscle biopsy?(2)
149. Enumerate storage options available in digital photography of pathology images.(2)
150. What is marrow stainable Iron? How is it estimated?(2)
151. Outline principle and methodology of Polymerase Chain Reaction.(5)
152. Give a brief outline of advances in the technique of microscopy(5)
153. What are the methods used for detection of mutations?(5)
154. CD 117 positive tumours(2)
155. Out line principle and methodology of FISH. Discuss its usefulness in diagnosis.(5)
156. Outline principle and methodology of automated cell counters(5)
157. Digital photography in histopathology.(10)
158. S100(5)
159. Tissue array.(5)
160. Electrophoresis(5)
161. Interpretation of synovial biopsies(5)
162. Importance of calibration verification in clinical laboratory(5)
163. Aggregometer(5)
164. Describe principles and applications of flow cytometry.(5)
165. Discuss role of automation in clinical pathology.(5)
166. Discuss the available immune markers in diagnostic pathology. Mention the recent
advances in identification of tumors by immuno-histochemistry(10)
167. Automated cell counters (5)
168. Flow cytometry(5x2); Clinical applications of flow cytometry(5)
169. Cytospins(5); Cytobrush(5)
170. Applications of cytocentrifuge(5)
171. Cytokeratin expression in various neoplasms(5)
172. Tissue arrays(5)
173. Advantages of diagnostic molecular pathology(5)
174. Discuss the diagnostic interpretation and clinical significance of serum enzyme and
isoenzymes in disease (10)
175. Role of IHC in histological disease(10)
176. Silver impregnation techniques in histopathology(5)
177. Cell block preparation and its diagnostic use(5)
178. Immunotherapy(5)
179. Proteolyic pretreatment of tissue sections(5)
180. Semen analysis(5)
181. Processing of bone marrow trephine biopsy(5)
182. Enzymes in tumour diagnosis(5)
183. Discuss the diagnostic interpretation and clinical significance of serum enzyme and
isoenzymes in disease (10)
184. Principles involved in enzyme activity determination(5)
185. Discuss PCR and its role in diagnostic pathology(10); PCR in early detection of
tumour(5)
186. Cryostat(5)
187. Levey Jenning’s chart(5)
188. Role of electron microscopy in the diagnosis of tumours with examples(10)
189. In situ hybridisation(5)
190. Electrophoresis(5)
191. PCR(5)
192. Bone marrow transplantation(5)
193. Hybridoma(5)
194. Chorionic villus sampling(5)
195. Scope of automation in hematology (10)
196. Peripheral smear examination (10)
197. What are a. knock out mice b. knock in mice?(2)
198. Types of nerve biopsy preparations.(2)
199. Stains used in vaginal cytology(5)
200.