Professional Documents
Culture Documents
VIJAYAMAHANTESH. M. HUGAR
In
PANCHAKARMA
Dr. P. Shivaramudu,
M.D. (Ayu)
And co-guidance of
2006.
Rajiv Gandhi University Of Health Sciences, Karnataka, Bangalore.
Date:
Place:
VIJAYAMAHANTESH. M. HUGAR
CERTIFICATE BY THE GUIDE
(Panchakarma).
Date:
Place: Dr. P. Shivaramudu, M.D. (Ayu).
Professor
M.D. (Panchakarma).
Date:
Place:
VIJAYAMAHANTESH. M. HUGAR
ACKNOWLEDGEMENT
“Many hands make light work”. I take this opportunity to mention my deep
gratitude to several personalities who have helped me in the successful completion of this
work.
I express my obligation to my honorable H.O.D, Dr. G. Purushothamacharyulu
M.D. (Ayu), H.O.D., P.G. Department of Panchakarma, P.G.S&R, D.G.M.A.M.C, Gadag
for his critical suggestions and expert guidance for the completion of this work.
I express my obligation to my honorable guide Dr. P. Shivaramudu M.D (Ayu),
Assistant Professor, for his critical suggestions and expert guidance for the completion of
this work.
I am extremely grateful and obliged to my co-guide Dr. Shashidhar.H.
Doddamani, Asst. Professor, P.G.S.&R, D.G.M.A.M.C, Gadag for his guidance and
encouragement at every step of this work.
I express my deep gratitude to Dr .G.B Patil, Principal, D.G.M.A.M.C, Gadag,
for his encouragement as well as providing all necessary facilities for this research work.
I express my sincere gratitude to Lecturer Dr. Santhosh. N. Belavadi MD (Ayu),
Lecturer for their sincere advices and assistance.
I express my sincere gratitude to Dr. V. Varadacharyulu M.D (Ayu), Dr.M.C.Patil
M.D (Ayu), Dr. Dilip Kumar M.D. (Ayu), Dr. Mulgund M.D (Ayu), Dr. K.S.R.Prasad
M.D. (Ayu) (Osm), M.A. (Jyotish), Dr. R.Y.Shettar M.D. (Ayu), Dr. Kuner Sankh M.D.
(Ayu), Dr. Girish Danappagoudar Dr. Jagadish Mitti M.D. (Ayu), Dr. Shashidhar
Nidagundi M.D. (Ayu) and other PG staff for their constant encouragement.
I express my sincere gratitude to Dr. Venkatesh S. Karanth M.D. (Patho) D.N.B.
Lecturer Shri. Nandakumar (Statistician), for their sincere advices and assistance.
I also express my sincere gratitude to Shri. V.M. Mundinamani (Librarian), Dr. S.
D. Yerageri, Dr. D. M. Patil, Dr. S. A. Patil, Dr. P.C. Chappanamath, Dr. M. V. Aiholi,
Dr. B. S. Patil, Dr. S. B. Govindappanavar, Dr. B. G. Swamy, Shri. C.S. Bhatt, Dr. U. V.
Purad, Dr. Mallagoudar, Dr. R.K. Gachhinmath, Dr. G.S. Hiremath, Dr. Avvani, Dr. S.
H. Radder, Dr. C. S. Hiremath, Dr. Juktihiremath, Dr. Kudarikannur, Dr. R.R. Joshi, Dr.
K.S. Paraddi, Dr. V. M. Sajjan for their support in the clinical work.
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Shri. B.S. Tippanagoudar (lab technician), Shri. Basavaraj (X-ray technician), Mr.
Shavi, Mr. Nabhi, Mr. Kulkarni, Mr. Hatti and other hospital and office staff for their
kind support in my study.
I express my sincere thanks to my colleagues and friends Dr. Ratna Kumar, Dr.
Uday Kumar, Dr. Jayaraj Basarigidad, Dr.P.Chandramouleeswaran, Dr. Kendadamath
Dr. Shaila. B, Dr. Santhosh.L.Y, Dr. Subin Vaidyamadham, Dr. Febin .K. Anto, Dr,
Satheesha.R, Dr., Dr. K. Krishnakumar, Dr. Ashwini Dev, Dr. Suresh Hakkandi, Dr.
Vijay Hiremath, Dr. Manjunath Akki, Dr. L. R.Biradar, Varsha.S. Kulkarni, Dr.
Hadimani, Dr. C. S.Hanumanta Gouda, Dr.Shankargouda, and other post graduate
scholars for their support.
I also express my obligations to my friends Dr. B.L. Kalamath, Dr. Venkareddy,
Dr. Basavaraj Ghanti, Dr. Pradip, Dr. Sajjan, Dr. Ashok Bhingi, Dr. Umesh Kumbar, Dr.
Devendrappa Budi, Dr. Shubu Prasad, Dr. Ashok M.G., Dr. Payappagouda, Dr.
Madhushri, Praveen. Dr. hemanta. Manju. Kushi. Kittu. etc.
I acknowledge my patients for their wholehearted consent to participate in this
clinical trial. I express my thanks to all the persons who have helped me directly and
indirectly with apologies for my inability to identify them individually.
I am highly thankful to my parents Shri. Mahadevappa D. Hugar & Smt.
Sarojadevi M. Hugar for her constant help and encouragement throughout the work. I am
also thankful to my beloved brother Mr. Vasanth Mrs. Geetha for their constant support
and encouragement.
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ABSTRACT
Ayurveda too deals with the chapter of urinary obstruction under Mutraghata and also
principles of its managements. Here a sincere attempt is made to asses the efficacy of
Research begins with doubts and ends with facts, that serve as new data to be
verified again. Thus the process of research never ends, but at the end of it the researcher
(BPH)”
MatraBasti is one the most important among the Panchakarmas. It has already
been proved that the “Basti” is the choice of treatment Vata pradanavyadisas the
Vatashtila is one of the Vata pradanana vyadi. And Shamana Snehapana is indicated in
Sukumaras viz old age persons without any hesitation .The ingredients viz- Dashamula,
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Clinically this study deals with the management of patients of Vatashtila (Benign
Approximately one half of 50 years, by the age of 60 years 50 % of men have histological
evidence of BPH, and an estimated three fourths of all men over the age of 60
As life expectancy increases, primary care physicians will likely see significantly more
The main severity of symptom is not correlated with the size of the prostate. Many men
with enlarged prostate have no symptoms whereas others, some times with lesser
enlarged, experience severe symptoms. The management of BPH is divided into Non-
All these considerations provided a firm launch pad to make excursion into the
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30 patients are selected and are randomly categorized into two groups.
Group 'A' – 15 patients with Matrabasti with Sukumara Kumarak Ghrita, 8 days
Matrabasti with 70ml of Ghrita, 16 days for pariharakala total study duration was 24
days.
Ghrita, 16 days Shaman Snehapana with 30ml Ghrita, divided dose twice Daly up to 16
days and 8 days for pariharakala total study duration was 24 days.
Subjective parameters:
Mala, Mutra, Anila Sanga, Adhmana, Sashula yukta mutratyaga. And American
Objective parameters:
Subjective complaints were relieved significantly in the range of 38.88% patents from
good respond after the completion of Matrabasti in Group A, and 22.22% of patients are
from moderate respond, where as 22.22% of patients are from poor respond.
In the objective parameter 6.66% good respond, 26.66% poor respond. Comparing the
In Group B the range of relief was observed from subjective parameter 55.55% is
patients there is no any respond has seen. Comparing the subjective and objective
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TABLE OF CONTENTS
1. Introduction 1-4
2. Objectives 5-9
4. Methodology 82-104
5. Results 105-137
6. Discussion 138-168
7. Conclusion 169-171
8. Summary 172-173
9. Bibliography 1-16
LIST OF TABLES
LEAST OF FIGURE
Least of Graphs.
of cornea, at this same period the prostrate gland usually. I might perhaps say invariably
In Ayurveda, there are two main treatment principles explained i.e. (1) Shamana
(2) Shodhana. The Panchakarma comes under the Shodhana, because of their nature, i.e.
elimination or purification methods. It has been mentioned, the diseases which have been
treated with shodhana therapy, will alleviate the disease from its root cause Na-tesham
treatment, as well as in the two goals of Ayurveda i.e. Swasthasysa Oorjaskara and
Aturasya Roganut.
Ayurveda considered Jara chikitsa i.e. science of geriatrics as one of the eight
divisions of Asthanga Ayurveda. Ayurveda perceives ageing as a special entity and laid
down its own multidimensional treatment approach towards it, which stresses on Vata
pacification along with the nourishment of depleted Dhatus, by means of Rasayana and
eternal science. Total life span is considered as hundred years by our Aacharys in their
classics.
1 Introduction
Last phase of life span is considered as jara, which is natural and inevitable
process as the age advances and is associated with its own disorders. During this period
naturally depletion in Dhatu, Indriya, Veerya, Bala And Ojus occurs, gradually. As age
advances loss of hairs, wrinkling on skin of whole body, senile cough, and short breath
appears.
As per Ayurveda Jaravastha is associated with vitiation of vatadosha and is more
prone to Vatavyadi’s. Vatashtila is one of the vata predominant disease, which succeeds
with old age. Acharyas susrhutha explained Vatashtila under vata vyadi nidana in first
chapter.
Ageing is defined as the “Sense of a progressive generalized impairment of function
resulting in a loss of adaptive response to stress and growing risk of age related diseases” is
expected that with the present rate, in early part of next century, we will be having around
25% of population in a geriatric group. Among the geriatric problems major systems
involved are central nervous system, cardio vascular system and third major is urinary
system. Common urinary diseases which affects elderly men is Benign Prostatic
Hyperplasia. (BPH)
“Thrimarmeeyasiddhi” and considered as one of the Bastigata vikara, but not as a type of
Mutraghata. Acharya Sushruta and others explained regarding Vatashtila, in the context of
Mutraghata. The diseases like Vatashtila, and Mutragranthi, which are having similar signs
and symptoms to that of BPH. Out of the two, the signs and symptoms of Vatashtila are in
which is responsible for normal voiding of function. There by produces stone like swelling
“Ashteelavath Ghanam Granthi” which is firm, Sthira and Unnatha. Manifesting between the
Guda and basti pradesha, it leads to bahirmrga avarodini means obstruction of Mutra, Anila,
2 Introduction
NEED FOR STUDY
The long-term exposure to drug induced adverse events and the prohibitive costs are
the primary limitations of prevention therapy of BPH. In addition, effective medical and
surgical therapy exists when BPH ultimately does becomes clinically evident. Because there
is no clinically evidence, biochemical, or genetic predictors of BPH development or
progression. So every male is at risk. The ability to identify those individuals who are
predisposed to develop clinical BPH refractory to medical therapy would provide a more
compelling rational for prophylaxis. There is evidence that men with very large prostates are
at greater risk for developing urinary retention. (Jacobsen et al, 1997)
As the high incidence of disease Vatashtila (BPH) in elderly men, at the beginning of
the 4th decade of life, 8% of men have histopathological Benign Prostatic Hyperplasia. 50%
of men aged 51 to 60 yrs, and 90% of the men over the age of 80 yrs. Have histological
evidence of benign prostatic hyperplasia. Approximately 23 million men world wide suffer
In the management of Vatashtila (BPH), which is the out come of vitiated vata,
Acharyas gave importance to the Sneha as the choice of treatment. because Sneha is having
antagonistic properties to that of Vata. The Basti and Sneha are indicated in Mutrakricchra
and Mutraghata. In general Matrabasti is the major and effective treatment modality which is
easy to administer and can be given to old age persons without any complications. Shamana
Mutrakrichra, Gadhavarchas, etc. (Ch. Su. 13., Uttama Matra) (A. Hr. Su. 16/19) There
by these two remedies i.e. Matrabasti and Shamana snehapana are considered as the best
3 Introduction
In contemporary system of medicine various surgical approaches have been practiced
to relieve this embarrassing disorder of BPH. because medicines are practically of no avail.
associated with operative problems, hemorrhage etc. Incontinence of urine is noted in several
of cases post-operatively, which is more frustrating than the disease itself. The patient
doesn’t want to be treated surgically in the first instance, rather he prefers non-invasive
therapy. Acharyas elaborated the different kinds of treatment modalities regarding the
of Vatashtila Acharya Susrhuta mentioned, Swedana, Abhyanga, Basti Uttara basti, and
Kashaya, Kalka, and Sarpi. Susrhuta specifies treatment for Vatashtila in 5th chapter of
Chikitsa Sthana and he emphasizes to that of Gulma and Abhyantara Vidradivat Chikitsa
Vedana shyamaka. With regard to this Sukumara Kumaraka ghrita was considered for
this present clinical study as Matrabasthi and shamana Snehapaana in Vatasthila (BPH).
4 Introduction
To evaluate the effect of Sukumarakumaraka ghrita Matrabasti in the management of
Vatashtila (BPH).
well as BPH but acharya Sushruta has mentioned the term Pourusha which can be
and signs and symptoms. Vatashtila is one of the Vata pradhna vyadhi, incidence
of both are in old age persons, obstruction induced changes in detrusor muscle
function, compounded by age related changes in both bladder and nervous system
function, lead to urinary frequency, urgency and nocturia. Old age which is
inevitable stage of life also acts as Nidana for Vatashtila which is one among
of Basti marma.
of treatment, then also not recommendable. Because most of the patients in late
sixties and seventies, the risk for cardiovascular diseases, hypertension, diabetes
mellitus are high, serious post operative complications like hemorrhage, infective
processes such as Cystitis, and also delayed complications like urge or stress
risk of surgery and very less satisfactory results by the hormonal treatment. On
the aim of one should get rid of age related disorders like Vatashtila (BPH), here
Matrabasti is best treatment for old age persons, because of its less dose and
antagonistic to the Vata and the disease Vatashtila is vatadosha pradhana vyadhi
(Apanavata).
administered Basti dravya stays in Pakvashaya and it will reach to the affected
Hypothetically the Matrabasti can bring vitiated doshas to balanced state, severity
Matrasneha ) spared all over the body immediately and it can restore the normal
health.
By the virtue of active principles of Sukumara kumaraka ghrita it can spread all
over the body and reach the affected area, does the shamana of the disease.
Sukumaras viz old age persons without any hesitation. The ingredients viz.-
Rasayana, Balya, Shoolahara and Vatahara, etc., which helps in correcting the
inturn it acts on the nervous system related to the prostate because normal
This study has undertaken with the hypothesis that the Matrabasti is having better
results than the Shamana snehapana because as already mentioned the affected
This study has under taken to compare the effect of Sukumara kumaraka ghrita
To evaluate the effect of two groups, among two which is best treatment by
Vatashtila (BPH).
The main aim of the present study is not only reveals the symptoms of the
Vatashtila (BPH) but also induce reduction in size and weight of the prostate and
By Dr. Shivji Gupta, Dr. Ramesha Bhat, and Dr. M. Sahu, Varanasi.
10) Role of Mustadi Kalpa in the management of Mutraghata w.s.r. to B.P.H. - Dr.
11) A Clinical study on the role of Devdarayadi Kshaya and Dashmool Siddha Taila
Uttar basti in the management of Mutraghata w.s.r. to B.P.H. - Dr. N.H. Kulkarni
(2002).
(plant extracts) in BPH/LUTS. They have gained widespread usage since about
1990 among them (Plosker and Brogden, 1996), (Gormley et al, 1992),
Historical view is an essential part of the literature in which review is done about
the past events. Ayurveda starts since ancient period, before going to write any treatises
The Vedas are the first written documents of human civilization. Therefore the
Veda kala
Samhitas kala:-
and Matrabasti as the most effective therapeutic measure than any other such methods
prescribed for various ailments especially in the diseases occurring due to Vatadosha.
Acharya Charaka has described the Bastikarma, its usage, dosage, advantages,
10 Historical Review
Madhyama kala
combinations to the Ayurvedic world for a better practice.7 Acharya Kashyapa equated
Later, modern authors in Ayurveda has also elaborately explained the Bastikarma,
SNEHA
Veda Kala
In Rigveda description of many herbal plants and qualities of Tila Pinji Tilataila,
Sarshapa, are available. The Atharvana veda, gives plenty of references regarding the use
of Sneha therapeutically.9
Samhita Kala
various disorders. The author has devoted an entire chapter in the Sutra Sthana on
“Shadvidopakramas.”10 (Ch. Su. 22nd) Snehana as Pradhana karma is the most significant
therapeutic procedure. Among them Charaka has extensively dealt with the subject
“Snehana” and its Qualities, doses, time sedulous, advantages, complications, and
dravyas, basic sources of Sneha dravya, indication and contraindications of Snehana etc.
11 Historical Review
Acharya Sushruta has contributed separate chapter on “Sneha” in 31st chapter of
Shodhana, Shamana and Brumhana and explained the preparation of “Sneha” i.e. Ghrita
and Taila.13 Also we found that number of references regarding the uses of sneha in the
Shodhana and Shamana or alleviation of different diseases. Types and qualities of Ghrita
Hridaya.14
Snehana in 22nd chapter of his Sutrasthana and added use of different ghrita and taila in
managing various Balarogas.15 Bhela one of the six celebrated disciples of Atreya has
mentioned the use of different Sneha in treating different disorders.16 Qualities of each
taila their specific indications have been mentioned in 14th chapter in Harita samhita.17
and Chakrapani they explained Paryayas, Swaroopa, Utpattisthana, Gunas of Ghrita and
Adhunika Kala
Detailed explanation about uses of both animal product ghee and plant products
oils, in materia medica and added classification of fats, oils, properties and sources of oil
expression of oils, have been mentioned. Textbook of pharmacognocy, Teiz’s text book
of clinical Biochemistry, etc are the textbooks where literary review regarding the use of
12 Historical Review
VATASHTILA
Vedic period
In vedic period there is no explanation about Vatashtila, but we can get references
with the use of “Loha Shalaka” this kind of references give as account of the knowledge
that our ancestors had with regards to the anatomical, physiological, pathological and
can be linked to nuclear energy, among the innumerable mantras. This type of
explanation we can get in Ayurveda also. i.e. Acharya Sushruta declares that student
desires of studying Ayurveda should be initiated into the regular practice of “Gayatri
Sannipataja jwara.
Samhita kala
This was the golden period of ayurveda and the two great works viz. Charaka
samhita and Sushruta samhita were written in this period. Acharya Charaka in 9th chapter
sambhandi vyadhis among those Vatashtila is one of the mutravarodha janya vyadhi.23
hridayakara including Kashyapa fallowed the same view of Charaka and Sushruta.27
13 Historical Review
Madhyama kala
The important work has been done in the text book of Chakradutta28 and
Bhishajyaratnavali29 have given more concentration over Chikitsa with different Yogas in
Gangadhara and Dalhana have fulfilled their commentary for the better understanding of
the Samhitas.
14 Historical Review
Yutpatti and Nirukti of Basti
The word Basti is derived form ‘vas + tich’ and is masculine gender.
Paribhasha
The term Basti means bladder. It is used as a device for Bastikarma. Hence, the
term Basti is used as a name in Panchakarma therapy to designate the process. The
medicated decoctions, milk, oil, ghee, mamsarasa of prescribed quantities are taken in
Basti and introduced into Gudamarga by means of a device Bastinetra after proper
pretreatment procedures.
SNEHA NIRUKTI
The word ‘sneha’ is derived from the root “sniha” with “Lute” pratyaya
The word Sneha is masculine gender and is derived from “Snih” Dhatu by suffix
“Lyut” Pratyaya
The term Sneha implies that a substance that brings oiliness or unctuousness.
PARIBHASHA
Kleda is moistness, which signifies the increase in apya guna of body. It means the
Snehana is the process by which Snigdhata, Vishyandana, Mardavata and Kledana are
produced in the body. These measures are adopted to bring about snigdhata in the body is
known as snehana.
text. It is refers to internal administration as well as external use of Sneha. There are such
specific nomenclature used for external application of sneha i.e. Abhyanga, Lepa, etc for
Hence which does the Shaman or normalizes the aggravated doshas all over the
body is Shamanasneha.37
Ashtila means it is situated in just above the Guda pradesha and below the Basti.
It is a feminine gender.
Meaning of Ashtila
It is a globular swelling. 39
PARIBHASHA
Astilavat Ghanam Granti Urdhwa Ayata Unnatam 41- means Ashtila is the hard,
round, stone like structure which is situated in between Vasti and Guda and its structure
Means which is cause for the difficulty in micturation, which will dries up the
The one which causes the obstruction of mutra and leads to difficult in
micturation.
Vranagata, Mutrashayagata.
But Charaka has used the term Basti exclusively for Nirooha as per the
commentary of Chakrapani.43 Similarly the term Basti has also been referred to the
Synonyms of Sneha
generates. No other elimination therapy is equal to Basti because it expels the vitiated
doshas rapidly and easily from the body and also reducing as well as nourishing the body
very fastly. Though emesis and purgation eliminate the vitiated doshas form the body,
the drugs used in these therapies contain Katurasa, Ushnaguna and Teekhsna gunas,
which cannot be taken easily by children or older people. But Basti can be given in all
Bastikarma is the best method of treatment in dealing with Vatavikaras and Vata
dominating other Vikaras as Vata being the chief controller among the causative forces of
disease.47 As per the fundamental principles of Ayurveda; vata is responsible for every
nature. On the other hand Vata is functionally required to co-ordinate with Pitta and
Kapha in order to accomplish various duties assigned to them in the organization of life.48
treatment to Pakwasaya helps for the proper regulation and co-ordination of the functions
of Vatadosha not only in its own site but also control the related doshas which are
treatment for Vata predominant disease and also called it as Ardhachikitsa by Vagbhata.50
Apart form this, Basti is considered as superior to the other therapeutic measures on
account of its varied actions like Samshodhana, Samshamana and Samgrahana of doshas
19 Review of Bastikarma
Basti is indicated for providing rejuvenation, happiness, longitivity, strength,
improving memory, voice, digestive power and complexion. It removes noxious matters
form the tissues, pacifies the doshas and rectifies the process of excretion. Consequently,
it affords stability and thus indirectly strengthens the reproductive capacity in man.52
Kashyapa equated the bastikarma as ‘Amrutam’, because of its wide application even in
Classification of Basti
among the authors of classical texts. Generally, the term Basti has been used for all types
of Bastikarma, which includes Nirooha, Anuvasana, Uttarabasti etc. But Charaka has
used this term Basti exclusively for Nirooha as per the commentary of Chakrapani.54
Similarly the term Basti has also been referred to the method of Shirobasti, Urobasti,
Vrina basti etc. So a rational thinking on various aspects of Bastikarma has brought about
1. Adhishtana bheda
a. Internal b. External
20 Review of Bastikarma
a. Internal
Pakwasaya.
Garbhasaya.
Mutrasaya.
b. External
In certain diseases the medicated oil is kept over the part of the body using a cap
or with flour paste for prescribed period of time and named after the site of application of
2. Dravya bheda
i) Nirooha basti – The main ingredient is Kwatha and it is the important type of
Bastikarma having varied therapeutic effects. The Basti is able to eliminate doshas form
the body and so called Nirooha. Also called Asthapana, as it is Vaya and Aayusthapaka
the Vikalpa of Nirooha basti are synonyms.56 The effect of Nirooha will spread all over
the body even in the cellular level and helps to eliminate the vitiated doshas adhered in
Srotases and its action in the body is beyond the perception of physician.57
21 Review of Bastikarma
ii) Anuvasana basti – Sneha is the chief ingredient of Anuvasana. The term
Anuvasana is coined due to the unharmful effect of the Bastidravya even if it is retained
inside the Koshta. More over this type of Basti can be practiced daily without any serious
3. Karma bheda
Sushruta and Vagbhata have made the following classification according to their
actions.59,60
¾ Brumhana basti – Increases the rasadi dhathus and indirectly it helps in the
deepana and pachana types of bastis.61 Vataghna basti, Balavarnakrita basti, Snehaneeya
basti, Sukrakrit basti, Krimighna basti, Vrushatvakrit basti has been explained in various
contexts by Charaka.62
22 Review of Bastikarma
4. Sankhya bheda
It is stated that neither snehabasti nor niroohabasti can be applied alone63 So,
Charaka has made this classification based on the number of snehabastis and
niroohabastis in a treatment.64
a) Karma basti – There are 30 numbers of bastis in this group out of which
then 6 nirooha and 6 anuvasana must be given alternately and in the end 3 anuvasana.
niroohabastis. First basti is anuvasana, then 3 nirooha and 3 anuvasana and last 1
5. Matra bheda
quantity may vary according to the age, strength of the patient and severity of the
disease.68
in different doses like 4,5,6,7,8,9, and 10 prasrutas, considering the strength of the patient
23 Review of Bastikarma
c) Padaheena basti – In this type of basti, 3 prasrutas i.e. ¼ of
dvadashaprasruta is less form from the total quantity of nirooha used i.e. 9 prasruthis.
sneha70used.
¾ Matra basti – The sneha that will be digested in 6 hrs if taken orally.72
6. Anushangika bheda
01. Yapana basti – Enhances bala, shukra and mamsa. Mostly employed in treating
the vyapats produced by excessive coitus. It can be given during all the seasons of the
years. It increases life span. Charaka has explained 26 bastis of this type. Kukkutamamsa,
ksheera, eggs, kwatha, madhu, ghrita, mamsarasa are should be added to prepare this.74
02. Siddha basti – The basti creates bala, varna, prasanata and it purifies more than
100 diseases.75
03. Yuktaratha basti – Mainly indicated for travelers on horse, different types of
vehicles etc.76
06. Ardhamatrika nirooha basti – No need for sneha sweda pratikriya. Sarvaroga
nivarana in nature, mainly rajayakhsma, shoola krimi, vatarakta. It improves sukha and
24 Review of Bastikarma
07. Pichha basti – It is given with a drug called as Shalmaliniryasa. It produces
08. Mutra basti – Gomutra is the main ingredient and it has the qualities of mridu
09. Rakta basti – When there is severe blood loss from the body, acharya has
advised to perform raktabasti that which stops the further blood loss and initiates the
production.82
Importance of Matrabasti
The term Matra conveys many meanings such as measurement, quantity, size,
duration, number, degree, unit of time and moment, but here in this context Matra refers
to measure i.e. quantity of Basti dravya as Ashtanga Hridaya states that Hhrusva matra it
As per Ashtanga hrudaya “Hrusvaya Sneha Panasya Matrayam” from the above
statement it is clearly understand that it can be given at any age viz. Bala, Vridha, etc
even for Alpagni person also. It is not having any complications due to its less quantity
of Sneha. Hemadri used the term Sukha which gives meaning of easy to handle.86
this quotation gives more importance to Matrabasti. Because during the administration of
Matrabasti it does not require any regimen like ahara chesta.. There is no any particular
25 Review of Bastikarma
Ashtanga Hridaya gives the terms like Nishparihara. Arunadutta added the word
Aniyantrana means, there is no any restriction for the day today activities and no Parihara
kala also as explained for other Bastis. No restrictions of time to follow other procedures
Properties of Matrabasti
Vatavyadhies.90
Vagbhata opines the same as Charaka and added it can be given regularly, which
is indicated for Bala, Vriddha, and Alpagni person also it as Varnya, Doshaghna etc.91
complications.92
As Matrabasti is variety of Anuvasan basti so the persons who are fit for
Table No. 01. Showing the indications for Bastikarma are as follows –
Sl. Indications C.A A.S H.S Sl. Indications C.A A.S H.S
1 Karma karsita + _ _ 8 Vriddha _ + +
2 Vyayam karsita + + + 9 Bala + + +
3 Bhara karsita + _ + 10 Chinta _ + +
4 Yana karsita + + _ 11 Stree _ + +
5 Durbala + + + 12 Sukumar _ + +
6 Vataroga + + _ 13 Alpagni _ + +
7 Bhagna + + +
26 Review of Bastikarma
Contraindications for Matrabasti
Acharya Charaka stated that it can be given regularly at any time and in all
seasons.97
Dosage of Matrabasti
So the dose of Matrabasti is equal to the quantity of Sneha which can digest
within 6 hours when taken orally. Acharya Dalhana mentioned the quantity of this as 11/2
phala i.e. 6 tola.99 Where as Kashyapa prescribed the quantity of Matrabasti as 2 palas as
Uttamamatra, 11\2 pala as Madhyama matra and 1 Prakuncha as Hriswa matra. He stated
that even half pala of Sneha can be given in Kaumara. (K. Khi. 8\104-105).100
Matrabasti Procedures
The mridu abyangha and swedana administered prior the pradhana karma. Then
advised to have alpha ahara a short walk. Patient must have passed natural urges. Then
made the patient laid on a cot comfortably, which is not very high and the head must be
at little lower level. Pillows should not be used. The patient should be in left lateral side
27 Review of Bastikarma
Pradhana karma (Treatment procedure)
The sneha prescribed for Matrabasti taken in the Bastiputaka and tied well placing
the Bastinetra in position. The entrapped air in Bastiyantra is expelled by gently pressing
the Bastiputaka. Then the anal region and the Netra should be smeared with oil. Gently
probe the anal orifice with the index finger of the left hand and introduce the Bastinetra
through it into the rectum up to first Karnika. Keeping in the same position press the
Bastiputaka with right hand with adequate and uniform force. Bastinetra should be
released carefully when a little quantity of sneha remained inside the Bastiputaka.106
The patient is kept lying on his back as long as it would take to count up to
hundred. The patient should be gently struck three times on each of the soles and over the
buttocks by Vaidhya’s own hand. The distal part of the cot should be lifted thrice. Allow
him to lie for sometime in the same position. If he gets the urge for defecation he may do
it. But in the event of sneha passed immediately another Anuvasana basti should be
administered. After passing the motion with sneha in proper time the patient is allowed to
take light food if he feels hungry.107,108 There is no specific duration of retention of matra
basti so we can consider duration of sneha basti. i.e. 3 yamas it means 9 hours.
28 Review of Bastikarma
SNEHA
Gunas in the drugs are responsible for the different functions of drug. The
properties of Sneha dravya’s are Snigdha, Sara, Drava, Picchila, Guru, Sheeta, Manda
and Mrdu, which are having opposite properties to Rukshana dravyas. Though drug
having these qualities but always it may not produce Snigdhata in the body. There are
few exceptions to this general rules like Yava, possesses Guru, Sheeta, Sara gunas
produces Rukshata. Rajamasha in spite of having Guru guna produces rukshata. Tila taila
is having Tikshna and Ushna it acts like Snehana. That may be the reason why Acharyas
Table No.02 : Showing the Sneha guna, Panchabhoutika sanghatana & Karmukata
of Sneha dravyas.112
apyamahabhuta predominant.
29 Review of Sneha
PROPERTIES OF CHATURVIDHA SNEHAS
1. Ghrita
Rasa – Madhura.
Veerya – Sheeta.
Vipaka – Madhura.
Prabhava – Agnideepaka.
Following are the conditions in whcih the ghrit can be used efficiently –
Vata-pitta Prakrti persons, Vata-pitta pradhana Vikratis, those desirer of longevity, Bala,
Varna, Swara, Pushti, Smriti, Medha, Dhee, and the some oft the conditions like
2: Properties of Taila
Rasa – Madhura.
Veerya – Sheeta
Vipaka – Madhura.
30 Review of Sneha
Karma – Vata-kaphahara, Pittakara, Balakara, Varnya, Twacha
Bhagandara, Krura Koshta, and along with those desires of Bala, Tanutva, Laghuta,
3. Vasa
Properties – These are similar with the Mamsa of animals from which they are obtained.
Due to vast origin and qualities of Vasa, it is indicated for the Mahat agnibala
persons along with those who are capable of bearing klantata of ruksha Vayu and Atapa,
karshatwa due to carrying of excess weights and it is found much beneficial in the vikritis
4. Majja
This is the most heaviest sneha dravya. Hence, indicated in persons having
Diptagni, able to bear Klesha, having Krura Koshta and habituated to Sneha. 113,114,115,116
31 Review of Sneha
CLASSIFICATION OF SNEHA
Sthavara Jangama
Sthavara sneha is extracted from plant source. Phala, Sara, Mula, Tvak, Patra &
Pushpa are the main sources of Sthavara sneha. Charaka has told eighteen Ashayas of
Sthavara sneha.
Action
32 Review of Sneha
B) Jangama Sneha (Animal Origin)
Jangama Sneha is derived from animal sources. eg. Ksheera, Dadhi, Ghrita,
Opinion of different authors regarding varieties of Sneha paka and its indications
Table No. 05. Showing Sneha Bhedha based on the Paka. 121,122,123.
Samyoga Bheda
Upayoga Bheda
33 Review of Sneha
V. PRAYOGA BHEDA 128,129
Prayoga Bheda
Vishistha sagna
The following dosage schedule is advocated in the classics based on the time
Vagbhata has mentioned about Hrasiyasi Matra the quantity of Sneha, which
digests within three hours, is known as Hrasiyasi Matra. This is used when the Koshta of
the person has not been properly diagnosed.135
Fixing the Dosage of Sneha in numerical value is not possible with the reason
that, dose will vary from person to person based on Dosha, Kostha and Agni level. Hence
dosage of the Sneha is explained based on the time required for the digestion of Sneha
viz,
01. Hrasiyasi Matra. 02. Hrasva Matra.
34 Review of Sneha
Table No. 06. Showing Opinion about Sneha Matra 135,136,137.
35 Review of Sneha
Hrasiyasi Matra is a trail dose, which is administered on the first day of
Snehapana.
Uttama matra should be used for Shamana and not for Shodhana poorva snehana. So
doubt may arise regarding usage of Uttama and Hrisva matra as Shodhana poorva
snehapana.
sneha during Annakala when one feels hungry without taking the meal.141,142. Hemadri
defines Shamana snehana is one which normalizes the aggravated doshas without
The sneha used for Brimhana is called as ‘Bhrimhana sneha’. The administration
of Sneha along with Mamsa rasa, Madya, Ksheera etc., are known as Brimhana
snehana.144 If, Brimhana sneha is given before food, it will cures Adhobhaga rogas, if
given in the middle of food cures Madhyamabhaga rogas and if given after food cures
Urdhwabhaga rogas and strengthens the body.145 But, here the dose of Sneha should be
36 Review of Sneha
(iii) Shodhana sneha
preceding evening food has been digested but individual have shown less hunger is called
as Shodhana sneha.147,148,149.
Though the Acharyas explained about Shamana sneha but they did not defined it
clearly. But Arunadutta, the commentator of Ashtanga Hridaya stated that “Rogascha
Shamana Yopa Yuchyate Sneha” which normalizes the aggravated doshas all over the
Charaka has explained Uttama matra of sneha for the person who is having
Uttama koshtaagni and bala, who can withstand thirst, hunger and fatigue (kshut,
pipasa). If we administered properly, it can does the shamana of the sarva shareeravyapi
Indriyachetasam. (Ch. Su. 13 Uttama Matrasneha) and (A. Hr. Su. 16/19) and it has the
capacity to spread in to sarva shareera like entering into Marma, Asthi and Sandhi. It
cures the vyadhis like Gulma, Sarpadamshtra, Visrpa, Mutrakricchra, and it evacuates the
bowel easily. It enhances the Bala, Indriya and Manaprasannata. Arunadatta states that it
“Sneha Viriktavat” after the digestion of sneha. (Ah. S. 16/19, Ch. Su. 13/81) Because
37 Review of Sneha
MATRA OF SHAMANA SNEHA
Regarding the posology of Shamana snehapana there is quite controversy between
Acharya Charaka and Vagbata. Charaka while describing the dose schedule for sneha,
says that Uttamamatra or optimum dose of sneha which gets digested with in 24 hours is
the more suitable dose for Shamana sneha.155 Vagbhat opines that the Madhyama matra
sneha which gets digest within 12 hours is the more suitable dose for Shamana sneha.
Where as Ashtanga Hridya added that for Shodana purpose Matra should Bahu, but for
Shamana purpose Madhyama matra should be used,156 It seems to be the time which is
taken for the digestion of Sneha dravya is one and same, but there is no contradictory
explanation by Charaka. Because Uttamamathra sneha will digest within 24 hours
Madyama matra will digest within 12 hours and Hrisvamatra will digest within 6
hours.157 , 157 (a)
Shrangadhara relatively more recent author has determined the dose depending
upon the digestive capacity of a person. Sneha for person of good digestive capacity is
one phala, for the person of medium digestive capacity is 3 karsha, and person of poor
capacity will be 2 karsha, which are considered as pradhana, madhyama, and hrisva matra
respectively.158 A close and critical analysis of the edition of the samhitas would appear
that, there is a gradual decreases in the dose of shamana sneha with the evidence of age.
This may be due to the decrease in the strength and power of digestion of the people with
advancement of age.159,160
The validity and applicability of Uttama and Madyama matra are Shamanasneha
matra according to Charaka and Vagbhat respectively. In the present day the person can
not withstand such a high dose of sneha. Hence it is favor to adopt the principal of
Sharangadhara that the dose of sneha should be decided as Heena, Madhyama, or Uttama
matra depending on the condition of Dosha, Kala, Agni, and Vyadhi of the patient. Even
the Chakrapani while commenting on Charaka opines that there is no fixed dosage of
drugs, but the dose is to be prescribed by considering the state of Doshas, Agni balabala
and nature of disease.
38 Review of Sneha
The author of the Ayurvediya Panchakarma Vigynana Dr. H. S. Kasture has
written the administration of Sneha as 6 tolas in 3 divided doses in a day for Shamana
purpose.161
regarding duration of administration. But, Kasyapa while describing the effects of the
snehana considers the vyadi shamana laxanas like “Karnakshi Pranabalam”, “Smriti
Kashyapa suggests that Shamansneha should be continued till the alleviation of the
39 Review of Sneha
Table No.10 This table shows General Contraindications of Snehana.166,167,168,169,170.
Sl. Asnehya C.S. S.S. A.H. K.S. Sh.S.
1
Rukshana, Samshodhanadrute + - - - -
2
Utsanna Kapha Medasa + - - - -
3
Kapha prakopa, Dagdha - - - + -
4
Abhishyanna anana guda + - - - -
5
Nitya Mandagni + - + - -
6
Shleshma Pittopahata antaragni - - - + -
7
Tikshnagni - - + - -
8
Durbala + + + - +
9
Pratanta (Klamayukta) + - - - -
10
Shranta - + - - -
11
Shramanvita, Akala Prasuta - - - - +
12
Garbhini + - - + -
13
Prasuta - - - + -
14
Apaprasuta, Urustambha, Udara - - + - -
15
Kshirapa, Ativriddha, Jadya, Glani - - - + -
16
Madatura, Murcha, Trishna + - - - -
17
Talu Shoshi + - - - -
18
Sneha Glani + - - - -
19 Garardita + - - - -
20 Amajahara + - - - -
21 Annadvesha + - + - -
22 Arochaka - + - + -
23 Ajirna - + - - +
24 Chardi + + + + +
25 Atisara - - + - -
26 Vit Prakopa - - - + -
27 Taruna Jvara - + - + +
28 Sthula - + + - -
29 Gala roga - - + + -
30 Akala datta Vireka, - + + - -
31 Akala Datta Basti + + + + -
32 Akala Datta Nasya + - + + -
33 Durdina - + - - +
40 Review of Sneha
SUITABLE RITUS FOR SNEHA
ACCORDING TO DOSHA
When there is Kapha associated with Vata or Kapha alone Sneha has to be
When the aggravation of Pitta and Vata, Pitta associated with Vata or Pitta
Poorvakarma
Athura siddatata
care should to be taken about Sama and Niramavastha of the patient before giving
through out the dhatus of the body such an attempt seldom gives the desired effect.
Shamana sneha should be administered when the doshas are in Paripakwa avastha
samgraha and Hridayakara advised mridu bhojana prior night of Shamana snehapana.
Because his previous food should digest completely and should feel hunger (bubbukshita)
then only he is fits for Shamana snehapana. When the patient is not having proper
appetite the administered sneha will not be able do its desired effect and may leads to
doshotklesha. So one must be very particular about the appetite while administering
Shamana sneha.174,175
41 Review of Sneha
Pradhanakarma
The Shamana sneha should be administered during the anna kala, when the
patient feels hungry, advise to take Snehapana by praying the God and devoting respect
to the elders.177
Pashatkarma
The physician should take care of three things in Paschyata karma viz.
i.
Anupana.
ii.
Peyadi krama. (Sneha viriktavat)
iii.
Pathya pathyha.
Anupana 178,179,180.
Particular Anupana should selected and given along with the Snehadravya.
Charaka has mentioned particular type of Anuapna dravyas in respect with sneha
dravyas viz.
In the non availability of particular Anupana dravya Ushnajala can be used except
in case of Tuvaraka and Bhallataka Taila. The dosage of the Anupana should be decided
42 Review of Sneha
Peyadi Krama (Sneha viriktavat)
After the digestion of sneha patient should follow sequence of regimens as a part
of post-operative care –
Ushna yavagu, Saklinna alpatandula, Krita yavagu, Krita vilepi with alpa ghrita.
Snehae Virikthava.181,182,183
Pathya Pathyha
Pathya 184,185,186,187.
Apathya
¾ Vyayama – Exercise
43 Review of Sneha
Table No. 11. Showing Sneha Jeeryamana and Jeerna Lakshana.188
44 Review of Sneha
SHARRERA OF ASHTILA
Ashtila is the hard, round, stony like structure . Acharya sushruta explained very
clearly about structure and its location in the body.189 It is located in Shakrunmarga i.e.
STRUCTURE OF ASHTILA
02. Charmakarinam – Means it is very hard mass which feels like metallic one i.e.
(loha, bhandi).
03. Ayata – Means to arrive, to adhere. Here Ayata means Granthi, which is like
Ayatakara. It can be compare with prostate when it enlarges with right and left lateral
lobes.193
04. Urdhwa – It means perhaps raised, tending upwards or raised elevated. It can be
smooth muscle cells and granular epithelial tissue, but it can be compared with prostatic
cancer.
hyperplasia there will be partial movement, where as in prostatic cancer it will be fixed
one.197
45 Shareera
RECTUM / GUDA
Sushruta has explained about the anatomical structure of Guda while describing
Arsharoga. Guda is a part, which is the extension of sthoolantra with 4½ angula in length.
yavapramana. The first vali samvarani starts at a distance of 1 angula from gudostha. The
width of each vali will be 1 angula and resembles the colour of elephant’s palate.201
Charaka when described about the Koshatagni has considered Uttaraguda and
respectively.202
All Acharyas have considered Guda as one among the Dashajeevita dhamanis and
The rectum forms the last 15 cm of digestive tract and is an expandable organ for
the temporary storage of fecal material. Movement of fecal material into the rectum
The last portion of the rectum, the ano-rectal canal, contains small longitudinal
folds, the rectal columns. The distal margins of rectal columns are joined by transverse
folds that marks the boundary between columnar epithelium of the proximal rectum and a
stratified squamous epithelium like that in the oral cavity. Very close to the anus or anal
orifice, the epidermis becomes keratinized and identical to the surface of the skin.
46 Shareera
There is a network of veins in the lamina propria and submucosa of the ano-rectal
canal. The circular muscle layer of the muscular is extern in the region forms the internal
sphincter and are not under voluntary control. The external anal sphincter guards the anus
and is under voluntary control. Pudental nerves carry the motor commands.206
BASTI
Nirukti - The term Basti is derived from the root ‘Vas nivase’ which is suffixed
According to Shabdastomamahanidhi -
It means, the organ, which acts as receptacle or lodges or hoarded or covers the
the organ where Mutra stays or resides or in other words Basti acts as a reservoir of urine.
Mutrashaya (Su. Ni.3), Basti (Su. Ni.3), and Basti puta (Vijayarakshita on Ma. Ni.31).207
Uthpatti - The essence part of the Rakta and Kapha after being digested by Pitta
along with Vayu forms the Basti, Antra and Guda (Su. Sha.4).208 Further in this context
Sushruta explains that the hollow shape is formed when the essence parts are inflated by
the repeated action of Vayu (Su. Sha.4).208 Charaka has not explained about the
47 Shareera
Number, Location, Relations - Basti is only one and is one of the Koshthanga
(Ch. Sha.7, Su. Sha.5, Su. Chi.2, A. Hr. Sha.3), Saptashaya (Su. Sha.5) and Dasha
Regarding the location, Sushruta and Vagbhata opines that the Basti lies between
the Nabhi, Prushtha, Kati, Vrishana (Mushka), Guda, Vankshana and Shepha
(Medhra/Linga). The Basti, Bastishira, Pourusha, Kati, Vrishana and Guda are all related
to one another and situated within Gudasthivivara (Cavity of rectal bone/Pelvic cavity).
Further in the chapter of Ashmari Nidana,209 Sushruta and also Vagbhata states that in
females the Urinary bladder is situated very near and side to the Uterus (Su. Chi.7, A. S.
Acharya Charaka mentions that Basti is located in the midest of Sthula Guda,
Mushka, Sevani, Shukravaha and Mutravaha Nadi, is the receptacle of urine into which
all the channels of the body carrying liquid elements converge as all the rivers on the
earth flow into the ocean (Ch. Si. 9). Further Chakrapani commenting on the same verse
explains that Basti is the resort (Ashraya) of all the surrounding organs and it is the
resting place of Ambuvaha srotas. The channels connected to their moola which are
Marma and which provide nourishment to them because of which even these channels are
called as Marma. Bhavamishra and Sharangadhara have mentioned that the Basti is
located below the Malashaya (Sha. Pu. Kha.5). Amarasimha mentions it to be situated
Size - Acharya Sushruta mentioned that the size or pramana of Basti marma is
48 Shareera
Shape - The shape of the Basti is similar to Alabu (Gourd) (Su. Ni.3), whereas
Acharya Vagbhata says that it has a shape of Dhanurvakra - a bent bow - (A. H. Sha.4).
Adhamalla commenting on Sha. Pu. Kha.5 mentions that it is having resemblance (with
Structure - It is hollow viscera (Ashaya) (Su. Sha.5), having thin walled (Tanu
Twak) and a single outlet directed downwards, which is fixed on all sides by the Sira and
Snayu (Su. Ni.3, Su. Sha.5, Su. Sha.5). Here Snayu are of Sushira variety. Structurally it
is composed of very less Mamsa and Rakta dhatu (A. H. Sha.4, A. S. Sha.7). Basti is
devoid of Mamsa and Meda dhatu (Dal. on Su.Ni.9) Basti is counted under Sadya
Pranahara marma and Snayu marma having vital area of about 4 Angulas (Su. Sha.6) and
Synonyms - Mutra Praseka (Su. Chi.7), Mutra patha (Ch. Chi.26), Mutra vahi
Srotas (Dal - Su. Ut.58), Mutra Seka (Su. Chi.7), Mutra Marga (Ch. Si.9, Su. Chi.7, Su.
Ut. 58), Mutra Srota (Su. Ni.13, A. Hr. Ni.9), Mutrayanam (Madhukosha - Ma. Ni.27).
Mutrapraseka -
There are no direct references available regarding the size, shape and other
specific anatomical details of Mutra Praseka but some relevant and cross references in
Uttara Basti chapter gives a superficial idea about the length of Mutra praseka. Wherein
the Uttara Basti (Pushpa) netra pramana is said to be of 12 or 14 angula in male and 10
angula in female (Ch. Si.9, Su. Chi.37) Further it has been explained that in males it
Therefore the length of Mutra praseka in male is about 6 to 7 angula. In female it has to
49 Shareera
Applied aspect - While explaining the surgical approach to Ashmari Sushruta has
said to prevent Mutra praseka from any injury, otherwise dribbling of urine will become
continuously (Su. Chi.7). Sushruta describes that below the opening of the urinary
bladder (Bastidwarasya chapyadhah - internal urinary meatus) and two fingers on the
right side (Dwayangule Dakshine parshwe), the Shukra enters and flows out through the
urinary passage (urethra) of the man (Su. Sha.4, A. S. Sha.5). It also opens from left side
Suppression of urge of urine during sexual intercourse leads to Shopha and Ruja of the
Mutrashaya, Guda, Mushka and leads to retention of urine. Urologists are also of same
opinion that due to aforesaid cause retrograde ejaculation occurs in consequence to the
4 Anjali. (Ch. Sha.7) 1 Anjali is nearly about 4 ounces. So 4 Anjali is nearly about
16 ounces, (480 ml) which clearly indicates that Acharyas considered 4 Anjali only
because of the storage capacity of Basti. In 24 hours 1500 ml of urine is excreted out
instances.
The urinary bladder performs the function of Dharana (storage) and poshana
(release) of urine. The example of a ''taut bow" in relation to Basti signifies the
(Thick urine or abundant urine) and Sashoolam (With pain or Dysuria) (Ch. Vi.5).
50 Shareera
Any injury to Mutravaha srotas leads to the Anaddha basti (Distention of urinary
bladder), Mutranirodha (Retention of urine) and Stabdha Medhra (Stiffness of the penis)
(Su. Sha.9).
ANATOMY OF PROSTATE
the symptoms of BPH is a through comprehension of the normal and pathologic anatomy
Graphically the prostrate gland can be conceived of as an apple with the core
entirely removed. The hole thus produced through the center of the apple is the prostatic
urethra, which is contiguous with the bladder neck superiorly and the membranous
urethra inferiorly. This analogy with the apple can be carried further by thinking of the
skin of the apple representing the gland itself, which consists of fibrous, muscular and
glandular elements. The entire prostrate gland in a young, healthy adult man weighs
about 20gm is about the size of a large chestnut. Stephen N, Rous Textbook of Urology.)
The Prostate is located in the pelvis and is surrounded by the rectum, bladder,
dorsal and periprostatic venous complexes, musculature of the pelvic sidewall, the
urethral sphincter (responsible for passive urinary control), the pelvic plexus, and
cavernous nerves (which innervate the pelvic organs and corpora cavernosa). Sushruta
The Prostate is a firm, partly glandular, partly fibro muscular body, surrounding
the beginning of the male urethra. Being somewhat conical, it presents: above - a base or
vesicle aspect, below - an apex and also posterior, an anterior and two inferolateral
surfaces.
51 Shareera
The base is largely contiguous with the neck of the bladder above it; the urethra
enters here, nearer its anterior border. The apex is inferior and in contact with the fascia
on the superior aspects of the sphincter urethra and transversi perinei profundi. The
posterior surface, transversely flat and vertically convex, is separated from the rectum by
the Prostatic sheath and loose connective tissue external to the sheath. Near its superior
(Juxta vesical) border is a depression where the ejaculatory ducts penetrate the gland,
dividing this surface into a superior and an inferior, larger part. The superior part is
variable in size and usually regarded as the external aspect of the median lobe; the
inferior part shows a shallow, median sulcus, usually considered to mark a partial
separation into right and left lateral lobes, forming the main Prostatic mass and
continuous behind the urethra. A band of fibro muscular tissue, ventral to the urethra,
joins these lobes together and is often referred to as the anterior lobe; it contains less
glandular tissue than the rest of the gland. The anterior surface, transversely narrow and
convex, extends from the apex to the base, about 2 cm behind the pubic symphisis from
which it is separated by a venous plexus and loose adipose tissue. Near its superior limit
it is connected to the pubic bones by the puboprostatic ligaments. The urethra emerges
from this surface anterosuperior to the apex of the gland. The inferolateral surfaces are
related to the anterior parts of the lavatories ani, which are separated from them by a
The Prostatic base measures about 4 cm transversely, the gland being about 2 cm
fibrous sheath, partly vascular; on each side this consists fibrous tissue containing the
prostatic venous plexus; anteriorly it blends with the puboprostatic ligaments and
inferiorly with fascia on the deep surfaces of the sphincter urethra, the deep transverse
52 Shareera
perineal muscles and with the perineal body. Posteriorly the sheath has a different origin
and is a vascular. In male fetuses, at the forth month, the rectovesical peritoneal pouch
descends to the pelvic floor, separating prostate from rectum; its lower part is obliterated
and the fused peritoneal layers here form the posterior prostatic sheath, sometimes termed
the rectovesical fascia. Traces of its separate layers persist as a plane cleavage. Above, it
descends over the posterior aspects of the seminal vesicles and deferent ducts and is
connected to the floor of the rectovesical pouch; on each side, it joins with the posterior
vesicle ligament. Below, adherent to the prostate, it joins with the perineal body. The
anterior parts of the lavatories ani pass back from the pubis around the prostate as
levatores prostatae.
The prostate is traversed by the urethra and ejaculatory ducts, and contains the
prostatic utricle. The urethra usually passes between its anterior and middle thirds. The
ejaculatory ducts pass antero-inferiorly through its posterior region to open into the
prostatic urethra.
It is divided into a peripheral zone, a central zone, and a transition zone. The
anterior surface is covered by the fibro muscular stroma. Most cancers develop in the
zone. The functional unit is the glandular acinus, which consists of an epithelial
specific acid phosphatase are produced in the epithelial cells. Both stromal and epithelial
cells express androgen receptors and depend on androgens for growth. Additional growth
regulatory signals occur via paracrine signaling between the two compartments. In
cancer, the relationship between stromal and epithelial elements contributes to growth
53 Shareera
both in the primary and metastatic sites. The major circulating androgens in the blood are
02. In focal regions in the periurethral area after the age of 55. (Harrison's-I )210
The contemporary classification of the prostate into different zones was based on
the work of Mc Neal. He showed that it is divided into: the peripheral zone which lies
mainly posteriorly and from which many carcinomas arise, and a central zone which lies
posterior to the urethral lumen and above the ejaculatory ducts as they pass through the
Prostate; the two zones are rather like an egg in its egg cup. There is also a periurethral
transitional zone from which most Benign Prostatic Hyperplasia (BPH) arises. Smooth
muscle cells are found through the prostate, but in the upper part of the Prostate and
bladder neck (the internal sphincter) these sub serve a sexual function, closing during
ejaculation.
Sushruta explained the condition like Mutra shukra, which resembles to above
said explanation. The distal striated urethral sphincter muscle is found at the junction of
the prostate and the membranous urethra, it is horseshoe shaped with the bulk lying
The glands of the peripheral zone, lined by columnar epithelium, lie in the fibro
muscular stroma and their ducts, which are long and branched, open into posterolateral
grooves on either side of the verumontanum. The glands of the transitional zones are
shorter and unbranched. All these ducts, the common ejaculatory ducts and the prostatic
ducts, open into the Prostatic urethra. No wonder that infection of the prostatic urethra is
difficult to eradicate.
54 Shareera
Benign Prostatic Hyperplasia starts in the periurethral transitional zone and, as it
increases in size, it compresses the outer peripheral zone of the Prostate, which becomes
the false capsule. There is also the outer true fibrous anatomical capsule, and external to
endopelvic fascia. Between the anatomical capsule and the prostatic sheath lays the
abundant prostatic venous plexus. The prostatic sheath is contiguous with the strong
fascia of Denonvilliers' that separate the prostate and its coverings from the rectum. The
neurovascular bundles supplying anatomic innervations to the corpora of the penis are in
very close relationship to the posterolateral aspect of the prostatic capsule and are at risk
diathermy to these nerves may be the cause of erectile impotence after Transurethral
Prostatectomy. (Bailey and love) 211 Vagbhata and Sushruta had considered this as Abhighata to
Shukravaha srotas that leads to Klaibya or Marana as explained during the operative
procedure of Ashmari.
The peripheral and central zone of the prostate are divided according to newer
anatomical studies.
A dorsocranially located central zone with wide lumina and a high cylindrical
epithelium. The glands show papillary folding. The cellular cytoplasm is light and
granular. The stroma is loose. A transition zone, located mediolateral of the urethra.
Narrow glands and a very tight stroma characterize this zone. A peripheral zone with
loose stroma and glands such as are seen in the transition zone. In all three zones
glandular acini and ducts with basal and secretary cells are found.
55 Shareera
Prostatic Hyperplasia develops in the transition zone, while prostatic carcinoma
develops in 70 % of cases in the peripheral zone. Only 20 % of all carcinoma are found in
the transition zone, and these are usually highly differentiated incidental carcinoma.
Arteries - These are rami of the internal pudendal, inferior vesical and middle
rectal arteries.
Veins - They form a plexus around the prostatic sides and base, receiving in front
the deep dorsal penile vein and draining to the internal iliac veins.
Nerves - They come from the inferior hypogastric (pelvic) plexus. The prostatic
nerve supply is very abundant, the periurethral zone being innervated by nerves arising
peripherally. Numerous nerve fibres and ganglia, forming a periprostatic nerve plexus,
56 Shareera
PHYSIOLOGY OF PROSTATE
The prostate has a purely sexual function and in animals that have a seasonal
sexual life, it is rudimentary except during the rutting season. The normal adult Prostate
The glands of the Prostate consist of many follicle-like spaces leading into ducts.
The epithelium of the follicles secretes the prostatic fluid, which is thin and opalescent
Prostatic Fluid – The seminal vesicles produce their own seminal fluid, which
nourishes and gives volume to the sperm. During sexual excitement the seminal vesicles
empty their contents into the prostate, which, in turn, adds its own prostatic fluid to this
mixture. Some prostatic fluid precedes ejaculation, but most of the released fluid is added
to the sperm and seminal fluid to constitute the semen. Only about 5% of the final
mixture comprising the ejaculate is composed of actual sperm. Prostatic fluid is both a
lubricant and a carrier of sperm and constitutes about 20% of the volume of the semen.
The muscles of the prostate are very active in the expulsion of semen from the body at
sexual climax. The stimulation of the prostate that activates ejaculation is responsible for
much of the intense pleasure that immediately precedes ejaculation. This fluid in man is
slightly acid in reaction (pH = 6.4). It is rich in calcium (30 mEq/ltr) and citrate (150
mEq/ltr) and in the enzyme fibrinolysin (Plasmin) and Acid Phosphatase. The low zinc
status of most men who suffer from BPH abets chronic low-level infection because free
57 Shareera
Systemic hormonal influence (endocrine) and local growth factors (paracrine and
autocrine) were seen on prostate. Many local and systemic hormones whose exact
functions are not yet known govern the growth of the Prostate. The main hormone acting
on the Prostate is testosterone, which is secreted by the Leydig cells of the testes under
the control of luteinising hormone (LH), which is secreted from the anterior pituitary
that is found in high concentrations in the prostate and the perigenital skin. Other
androgens are secreted by the adrenal cortex but their effects are minimal. Estrogenic
steroids are also secreted by the adrenal cortex and, in the ageing male, may play part in
disrupting the delicate balance between DHT and local peptide growth factors and hence
increase the risk of BPH. Increased levels of serum estrogens, by acting on the
hypothalamus, decrease the secretion of LRHR (and hence LH) and thereby decrease
hormones secrete other locally acting peptides. These include epidermal growth factor,
insulin-like growth factor, basic fibroblast growth factor, and transforming growth factors
alpha and beta. These undoubtedly play a part in normal and abnormal Prostatic growth
58 Shareera
PSA is a glycoprotien, which is a serine protease. Its function may be to facilitate
immunoassay and the normal upper limit is about 4 υmol/ml. Its level in men with
metastatic Prostate cancer is usually increased to more than 30 υmol/ml and falls to low
levels after successful androgen ablation. Men with locally confined cancer have serum
PSA levels of about 15 υmol/ml or lower. Although PSA is a reliable marker for the
diagnosis of early Prostate cancer and BPH, as both diseases are compatible with PSA in
the range of 4 -12 υmol/ml. PSA measurement has superseded measurement of serum
Figure No. 02. Showing the vertical section of the pelvis showing the prostate in relation
59 Shareera
SAMPRAPTI OF VATASHTILA
NIDANA SEVANA
Vata prakopa in Vriddhavastha
Apanavata vikriti
Improper formation of successive dhatus
Kha Vaigunya
Bahirmargavarodhini
DASHAMOOLA
Drug Name Rasa Guna Veerya Vipaka Doshaghna Karma
Bilwa (Aegle marmelos) Kashaya, Tikta Laghu, Ruksha Ushna Katu Kapha Vata Grahi, Pacaka
Shamaka Agnivardhaka
Agnimantha (Premna Tikta, Katu, Kashaya, Ruksha, Laghu Ushna Katu Kapha Vata Shothahara,
integrifolia) Madhura Shamaka Pramehahara
Shyonaka (Oroxylum indicum) Madhura, Tikta, Laghu, Ruksha Ushna Katu Kapha Vata Shothahara,
Kashaya Shamaka Mutrala,
Patala (Stereospermum Tikta, Kashaya Laghu, Ruksha Ushna Katu Tridoshahara Shothahara,
suaveolens) Kapha Mutrala,
Vatahara Ashmarihara
Kashmarya (Gmelina arbora) Tikta, Kashaya, Guru Ushna Katu Tridoshahara Shothahara,
Madhura Kapha Mutrala
Vatahara
Shalaparni (Desmodium Madhura Tikta, Guru, Snigdha Ushna Madhur Tridoshahara Shothahara
gangeticum) a Kapha Mutrala Mehahara
Vatahara
Prishnaparni Utaria picta Madhura Tikta, Laghu, Snigdha Ushna Madhur Tridoshahara Shothahara
a Mutrala
Brihati Solanum indicum Katu, Tikta, Laghu, Ruksha, Ushna Katu Vata Kapha Shothahara Hikka,
Teekshna hara Shwasahara
Kantakari Solanum Tikta, Katu, Laghu, Ruksha, Ushna Katu Kapha Vata Shotha, Kasa,
xanthocarpum Teekshna Shamaka Mutrala
Gokshuru Tribulus- terestris Madhura Guru, Snigdha Sheeta Madhur Vata Pitta hara Mutrala,Vrushya
a Bastishodhana
Shothahara
Laghupanchamoola
Drug Name Rasa Guna Veerya Vipaka Doshaghna Karma
Kusha. Madhura, Laghu, snigdha Sheeta. Madhura. Thridhosha- Mutrakrcchra
Desmost- achyabipi- Kashaya. hara asmrighna.
nnta stap
Kasha. Madura, Laghu, snigdha. Sheeta. Madhura. Vata pittahara. Mutrala,mutra-
Saccharum- Kashaya. Krcchra,
Spontaneum Asmari Bedaniya.
Linn.
Nala. Madhura, Laghu, Snigdha. Sheeta. Madhura. Kapha,pitta Vrsya,mutrala.
Arundo,donax Tikta, Hara. Asmari,mutra-
Linna. Kashaya. Krcchra,hara.
Darba. Madura, Laghu, Snigdha. Sheeta. Madura. Kapha, pittahara. Mutrala,mutra-
Krcchra,
Chikitsa means, a combined operation of all the four factors, viz. the Physician
and the other three factors of commendable qualities, with the object of engendering the
concordance of dhatu when pathological changes have occurred in them due to different
has mentioneda special treatment i.e. “Gulma Abyantara Vidradivat”239 for Vatashtila
(BPH). But in Mutraghata chikitsa the chikitsoprakamas are depending upon the extend
Trividha sadyopranahara marma, so Basti marma paripalana must be kept in mind while
Basti receives nourishment only when the nutrient supplying channels are cleared and
Apanavayu made its sanchalana. Basti karma is well appreciated in Charaka samhita
siddhisthana. (ChSi.9/49).244
Avagaha Swedana that alleviate Apana Vata from its main place and removes
obstruction of Mutravaha Srotas and leads to normal voiding of Mutra. Abhyanga due to
its Mardava, Snigdha, Manda, and Guru quality alleviate Vata Dosha. All three types of
Basti are indicated i.e. Niruha, Anuvasana and Uttara Basti (Ch.Su.7, Ch.Chi.28). These
directly act on Vyadhi Udbhava and Adhishthana pradesha (Pakwashaya and Basti) and
disintegrate the Vatashtila pathology. Mutra Virechaneeya medicines and Uttara Basti
Sneha.245
75 Chikitsa
Hence at a outstretch the aim of treatment is -
¾ Nidana Parivarjana.
¾ Apanavata Anulomana246
¾ Making proper flow of Urine with Mutrala and Basti Shodhaka drugs.
¾ Nidana Parivarjana.
¾ Shodhana.
¾ Shamana.
¾ Shastra Pranidhana.
¾ Rasayana.
¾ Pathya-Apathya.
Ahara – Excessive use of Ruksha, Madya, Teekshna ahara and to avoid fasting for
long time.
76 Chikitsa
2. Shodhana – When Doshas are increased extremely Shodhana Chikitsa become
necessary. While describing the Mutraghata chikitsasutra Sushruta says that in case of
Snehapana, Snehana/Abhyanga and Swedana followed by Virechana till the Dosha are
eliminated out of the body and then Uttarabasti is advocated. (Su.Ut.58).247 In addition to
Charaka suggests the usage of Trividha basti Karma in Mutra Roga (Ch.Su.7,
Jeernantikamatra.249 After the digestion of Sneha food is given and followed by Sneha
once again. Here giving excessive dosage of Sneha makes Peedana of Dosha and there by
palliate the aggravated Dosha. Acharya Vagbhata advises Tailvaka ghrita for
Kshara, Asava etc. (Su. Ut.58). Further he says to administer Ashmari hara and Mutra
Udavartahara yogas (Su.Ut.58). Whereas Acharya Charaka states that after diagnosing
the predominance of morbid Dosha, these conditions should be prepared by the measures
curative of Mutrakricchra hara (ChSi.9/49). Acharya Vagbhata has devoted one full
77 Chikitsa
4. Shastra Pranidhana Chikitsa – It is further classified into two groups as
under Shalya chikitsa. On going through all the classics it seems to be that no operative
urethral catheterization to drain the bladder in retention of urine, can be traced back to the
Vedic period (A.V.1/1-3). Acharya Sushruta has included Mutra vishodhani Shalaka.
About its function, he has said that it does Marga vishodhana (Su. Su.7). In this context
of Veerataradi gana dravya and then it should be given to the patients of Mutraghata.
(A.H.Chi.11/39). It is mainly used for Rasayana purpose. Rasayana chikitsa plays very
important role in Vatashtila / BPH as it is seen in elderly patients where Vata dosha is
PATHYA-APATHYA
The entire Ayurvedic system of healing is based on two major principles that is
"Maintaining The Health Of Healthy Persons And Curing The Ailments Of The Patients".
Healthy living is the most important aspect of Ayurveda but unfortunately this has been
the most neglected part. This can be achieved only by the Pathya ahara, which can
nourish both body and mind. Importance of Pathya is to increase the digestive power
there by proper production of optimum quality of Ahara Rasa that nourishes the Dhatu
78 Chikitsa
“Food is the factor which sustains and supports the Dhatu, Oja, Shareera Bala,
Varna etc. This food depends upon Agni to contribute the nourishment of the body. It is
obvious that the Shareera dhatu cannot be nourished and developed when food is not
"No structure in the body can grow or develop or waste or atrophy, independent
of Srotas that transport dhatu." Hence every cell in the body requires nourishment thereby
necessitates the spread of Srotas up to cells or all over the body (Ch.Vi.5).
From the above explanation it is clear that these Srotas carry both Pathya and
Apathya ahara. Hence, Charaka defined Pathya, as "that one which is wholesome to
PATHYA APATHYA
Ahara Vihara Oushadha Ahara Vihara Oushadha
Shali, Avoid Abhyanga, Viruddha ahara Excessive Vamana,
Yava, excess Snehana, in relation to exercise, Teekshna
Madya, Vyayama Virechana, Basti Desha, Kala Sleeping, Oushada.
Takra, Vyavaya, Avagahasweda and Satmyaetc. sitting or
Dugdha, dharana- UttaraBasti Ingestion of wandering in
deerana Ruksha, cold weather
of natural katu,tikta and Suppression
Vegas. Kashaya . of natural
urges. Not to
travel
continuously
on vehicles.
79 Chikitsa
MANAGEMENT OF BPH
The treatment of any disease depends on the magnitude of the clinical effect and
the incidence and severity of treatment related morbidity, assessing the effectiveness of
treatment related morbidity, assessing the effectiveness of medical therapies for BPH.
A. Conservative – 'watchful waiting' - general advice about fluid intake i.e. less intake of
fluid after evening, avoiding caffeinated and alcoholic beverages, and smoking.250
Perineal Prostatectomy.
80 Chikitsa
3. Minimally invasive methods –
Intraprostatic Stents.
Diode Laser.
4. Clinical Endpoints –
incomplete bladder emptying; acute and chronic renal retention; urinary tract infection;
Relieving LUTS,
Decreasing BOO,
The treatment of any disease depends on the magnitude of the clinical effect and
the incidence and severity of treatment related morbidity, assessing the effectiveness of
treatment related morbidity, assessing the effectiveness of medical therapies for BPH.
81 Chikitsa
DRUG REVIEW
The main motto of this study is to assess the comparative effect of Matrabasti and
Among these four basic factors of treatment, Dravya has been awarded the second place.
The selection of a proper drug in the management of disease is very important. Therefore
sufficient attention should be given for selecting the drug. Ghrita, Taila, Vasa, Majja are
the best Sneha dravyas among all snehas. Out of these four, Ghrita is the best Sneha
Dravya for par excellence because of its power to assimilate the properties of the
substance.
pertaining to Mutrakricchra and Mutraghata. Sukumara Kumaraka Ghrita, the name itself
indicates it is recommended for Sukumaras i.e. old aged persons without any hesitation.
Vatashtila (BPH).
82 Methodology
Decision diagram to treat BPH
04. Mild
designing a methodology for conducting this research. Clinical trial is a way of research
and it is the best method to evaluate any drug or line of treatment. It involves the
on which postulations are made regarding the usefulness of the drug or therapy in the
disease. Hence, this trial is a carefully designed experiment with the aim of solving
Research Approach
out the difference between the base line data before and after treatment.
Study Design
The study design selected for the present study was prospective comparative
clinical trial. Here, Matrabasti, group of patients are compared with the Shamana sneha
group of patients. Demographic data and disease-specific data are collected according to
The results and conclusions of a clinical trial depends on the study design. The
aim of this study was to find out the effect of Matrabasti, and Shamana sneha, in the
management of Vatashtila (BPH). Therefore, two groups were made and the results
87 Methodology
Source of Data
Patients suffering from Vatashtila (BPH) were selected from the P.G.R.S & R
Hospital, Gadag.
The sample size for the present study was 30, patients suffering from Vatashtila as
per the selection criteria. Patients were randomly distributed to both the groups of equal
Shamanasneha.
Selection Criteria
The cases were selected strictly as per the preset inclusion and exclusion criteria.
A) Inclusion Criteria
B) Exclusion Criteria
2 Patients with other systemic and metabolic disorders viz:- urethral stricture,
88 Methodology
Data Collection
history pertaining to the mode of onset, previous ailment, previous treatment history,
examination findings were noted. Routine investigations were done to exclude other
pathologies.
specially benign prostate hyperplasia. When medical history focusing on the urinary tract,
specific things to discussed when taking the history of a man with BPH symptoms
inspection. We can observe the abnormalities in genital organs, etc. if residual urine in
Percussion – It is to understand the gas, watery or any mass. The bladder must
contain at least 150 ml of fluid to allow its detection by percussion. It can be used to
89 Methodology
TREATMENT SCHEDULE
Group A - Matrabasti
Poorvakarma – Patient was given the Sthanika mridu abhyanga and swedana
prior to the pradhanakarma. The abhyanga was done with Murcchita Tila taila. Then
advised to have alpa ahara and made to take a short walk. Encourage to pass his natural
urges previously, and asked the patient to lay down on table of suitable to his height, in
glicerine syringe. A quantity of 70 ml Ghrita was injected through the rectum in a luke
warm temperature, after the proper preparation of Dravya as per the classical method
followed as per classics. After the basti, the patient was made to lie on supine posture just
after (5 to 10 min) and gentle tapping was made on his buttocks, legs were lifted up, hips
were tapped thrice and made pressure over abdomen. Asked to wet for 10min in supine
posture, the same procedure was repeated for 8 days and it was conducted in a time
between 9.30 to 10.30 am. The time of administration, the time of retention and any
Pariharakala of 16 days was advised and reported asked the patient to report on
24th day counting from the day of initiation of treatment protocol and observation done
on 24th day.
90 Methodology
Group B – Shamana snehapana
shamana Snehapana. Because on the day of Snehapana, the food of the previous day must
have to undergo digestion and patient must feel hunger (i.e. Bubhukshita). Then only the
Pradanakarma – Next day morning i.e. on the day of Shamana snehapana after
elimination of routine urges, jeerna ahara lakshana should be assessed. Then the 15 ml of
Sukumaraka kumaraka ghrita should be taken with a fresh mind, enthusiasm, courage, by
praying God. Same procedure should be follow twice daily for 16 days.
under keen observation till the “Sneha jeerna lakshanas” appears. The patients were
report on 24th day from the day of commencing the treatment protocol.
Diagnostic Criteria
The diagnosis of Vatashtila (BPH) was made according to the signs and
symptoms of the classics and modern science explantion, also with objective parameters.
Signs and symptomatology of Vatashtila (BPH) are mentioned for its diagnosis, but those
may not be sufficient for the diagnose of this disease. Hence, for better understanding of
the diseases, and purpose of the adaptation of resent advancement of for the appropriate
91 Methodology
Table No. 16. Showing Chief Complaints.
Sl. Signs and symptoms Sl. Signs and Symptoms
01 Ashtilavatghana granthi 05 Adhmana
Urdhwa I-PSS (AUA) Symptoms
Ayata 06 Incomplete emptying
Unnata 07 Increased frequency
that correlates strongly with the overall score (high internal consistency reliability), and
the resultant score gives similar answers when administered again after a short period of
time (high test-retest reliability). The score correlates strongly with both previously used
indices and a response to global questions of degree of both from urinary symptoms
(construct validity) and discriminates between patients with and without BPH (criterion-
validity). It is now believed that the single most important criteria for therapy is the
symptom score.257
The standard evaluation for prostatic diseases includes the digital rectal
examination (DRE). It should be performed with careful attention to the size and
consistency of the gland, the presence of lesions of lesions within the gland, or evidence
of extension beyond its confines. Its importance can not be overemphasized. The
posterior surfaces of the lateral lobes, where carcinoma characteristically is hard, nodular,
and irregular, but indurations may also be due to fibrous areas in a benign hyperplastic
background or calculi.
92 Methodology
Figure No. 03. Showing the Digital Rectal Examination (DRE).
anal sphincter tone, and to rule out any neurologiic problems that may cause the
presenting symptoms. It establishes the approximate size of the prostate gland.in patients
who choose or require invasive therapy such as surgery, estimation of prostate size is
accurate mesurement in most of the cases. This is having most importance in diagnose. It
should be done very gently with a well-lubricated glove and 360 degree digital
exploration. At first, any pathogenesis in the lower anal canal should be ruled out. Before
performing DRE, the physician should place the palm of his other hand against the
patient's lower abdomen. The gloved, lubricated index finger is then inserted gently into
the anus. Only one phalanx should be inserted initially to give the anus time to relax and
to easily accommodate the finger. Thereafter, the prostate should be palpated giving due
attention to its size, consistency, shape, rectal mucosa, median groove, mobility, surfaces,
upper border of the prostate etc. Hyperplasia usually produces a smooth, firm or elastic
93 Methodology
Ultrasonography
A detailed USG of both abdomen and pelvis was carried out before and after the
treatment in relation to the bladder wall thickness, trabacular pattern, residual urine,
width, length) and approximate weight of the prostate, and further important is post voide
residual urine volume measurement, i.e. PVR urine is the volume of fluid remaining in
the bladder immediately after the completion of miturition. The studies indicate that
residual urine normally ranges from 0.09 to 2.24 ml, with the men being 0.53ml (Hinman
and Cox, 1967). 78% of normal men have PVR’s of less then 5ml, and 100% have
volumes of less than 12ml by (Di mare et al, 1963). Ultrasound is the standard diagnostic
instrument for the BPH. The size of prostate is estimated approximately by the
¾ Grade 1 – 20 to 25 gms.
¾ Grade 2 – 26 to 50 gms.
¾ Grade 3 – 51 to 75 gms.
94 Methodology
Criteria for assessment of Results
The assessment of result were made based on data collected as per subjective and
objective in all patients before and after treatment. Separate grading has been given far
Subjective grading
view of the (“AUA”) symptom score index, the following shown index has been prepare
according to the patient’s condition and associated with help of the Matrabasti and
No. of Pt.’s Less than Less than About half More than Almost
At all 1tim in 5 Half the time the time Half the time Always
sensation after
defecation of mala
¾ Grade 0 – Normal.
sensation Less than Half the time, and About half the time routine defecation).
more than half of the time, and almost always of his routine defecation.
95 Methodology
Overall Response Assessment Criteria for Malasanga
Poor response – Means, if severity is reduced by grade 1, then it is considered as
poor response to the treatment.
Moderately response – Means, if severity is reduced by grade 2, then it is
considered as Moderate response of treatment.
Good response – Means, if severity is reduced to grade 0, then it is considered as
Good response of treatment. If the bowel habit returns to grade 0, then that will
be considered as Good response.
Not responded – Means, if severity is not reduced or increase, then it is
considered as Not respond from the treatment.
Score chart for Mutra sanga
¾ Grade- 0 - 500-2500ml. Per day.
¾ Grade -1 - 400-500ml. Per day.
¾ Grade -2 - 300-400ml. Per day.
¾ Grade -3 - 200-300ml. Per day.
Overall Response Assessment Criteria for Mutrasanga
Poor response – Means, (If there is increase in micturation by 100ml and severity
is reduced by grade 1, then it is considered as poor response of treatment.
Moderately response – Means, (If there is increase in micturation by 200ml to
300ml severity is reduced by grade 2, then it is considered as Moderate response
of treatment.
Good response – Means (If there is increase in micturation by 400ml to 500ml
severity is reduced to grade 0, then it is considered as Good response of
treatment. If the severity is reduced from any other to grade 0, then it is
considered as Good response.
Not respond – Means (If severity is neither reduced nor increased, then it is
96 Methodology
Score chart for Anilasanga (By percussion and auscultation)
Good response to the treatment. If the Severity is reduced from any other to grade
97 Methodology
Moderately response – Means, if Saatopa (Bearable Ruja in Pakvashaya) is
reduced by grade 2, then it is considered as Moderate response to the treatment.
Good response – Means, if Atyugra ruja, and complete distinction in abdomen is
reduced to grade 0, and If the Severity is reduced from any other grade to 0, then
it is considered as Good response to the treatment.
Not respond – Means, if Severity is neither reduced nor increased, then it is
considered as No response to the treatment.
Score chart for Ruja/ Sasholaukta Mootratyaga
¾ No symptoms Grade 0 – Normal.
¾ Bearable Grade 1 – Mild.
¾ Unbearable Grade 2 – Severe.
Overall Response Assessment Criteria for Ruja / Sashoolayukta mutratyaga.
stage i.e. grade 0, and If the Severity is reduced from any other grade to grade 0,
The international prostate symptom score (I-PSS) which is identical to the AUA
(Cockettet al, 19992). The I-PSS was developed by the Measurement Committee of the
AUA. This is an integral part of virtually every epidemiologic study as treatment studies
in the field.
98 Methodology
AMERICAN UROLOGICAL ASSOCIATION SYMPTOMS INDEX & (I-PSS)
(Questionary for patients)
No. of Pt.’s Less than Less than About half More than Almost
At all 1tim in 5 Half the time the time Half the time Always
1. Over the past month,
how often you had a 0 1 2 3 4 5
sensation of not
emptying your bladder
completely after you
finished urination?
2. Over the past month,
how often you have 0 1 2 3 4 5
had to urinate again less
than 2 hours after you
finished urination?
3. Over the past month,
how often have you 0 1 2 3 4 5
stopped and started
again several times
when you urinated?
4. Over the past month,
how often have you 0 1 2 3 4 5
found it difficult to
postponed urination?
5. Over the past month,
how often have you had 0 1 2 3 4 5
a weak urinary stream?
6. Over the past month,
how often have you had 0 1 2 3 4 5
to push or strain to
begin urination?
7. Over the past month, how many times you did most typically get up to urinate form the
time you went to bed at night until the time you got up in the morning?
99 Methodology
Gradings for I-PSS Index
0, and if the severity is reduced from any other grade 0, then it is considered as
Objective gradings
Table No. 17. Showing Digital Rectal Examination Chart.
Enlargement Posterior Left Right Median Bilateral
of lobe lateral lateral
Size of Normal Mild enlarged Moderately Sever enlarged
prostate
Upper Not With difficulty Reached
border Reached reached
Consistency Smooth Firm to hard Hard
Surface Smooth Hard & Smooth Hard & regular
& irregular &
irregular regular
Mobility Fixed Mobile Slightly mobile.
100 Methodology
The DRE findings assessed by a above chart made score chart, and most of the
findings assessed by putting present and absent according before and after treatment.
¾ Grade 0 – Normal.
Good response – Means, if the size of prostate is reduced to grade 0, and if the
Severity is reduced from any other grade to grade 0, then it is considered as Good
¾ Grade 2– Reached.
101 Methodology
Overall Response Assessment Criteria for Upper border of Prostate.
as Good response.
No response – Means, if there is neither increase nor decrease in the upper border
¾ Grade 1 – Fixed.
¾ Grade 3 – Mobile
response.
Not response --. Means, if there is neither increase nor decrease in the mobility
102 Methodology
Table No.18 Showing Grade for U.S.G findings.
Residual Urine
Prostate Size
Antero - Posterior
Width
Height
Prostate Volume
Kidney Right Left Right Left
Hydronephrosis
Caculi
Gradings for weight of the Prostate
¾ Grade 1— Means (1gms to 2gms ) increasing from the normal weight of the
prostate.
¾ Grade 2— Means (3gms to 5gms) increasing from the normal weight of the
prostate.
¾ Grade 3— Means ( 6gms to 7gms) increasing from the normal weight of the
prostate.
Poor response- Means if weight of the prostate is reduced by grade 1 , and , then
103 Methodology
Good response- Means if weight of the prostate is reduced to grade 0. and If the
Good response.
Not respond-. Means, if there is neither increase nor decrease in the weight of
¾ Grade 1 – 10 to 50cc.
¾ Grade 2 – 51 to 100cc.
Poor response- Means if residual urine volume is reduced by grade 1, and then
Good response- Means if residual urine volume is reduced to grade 0. and If the
Good response.
Not respond-. Means, if there is neither increase nor decrease in the residual
104 Methodology
In the present clinical study subjective and objective changes were considered for
Shamana snehapana with Sukumara Kumaraka Ghrita. Thirty patients were selected after
fulfilling the criteria for diagnosis and were treated in the following two groups –
All the patients were examined before and after the treatment according to the
case sheet format given in the appendix. Both the subjective and objective changes were
Demographic data.
Data related to subjective and objective parameters before and after treatment.
DEMOGRAPHIC DATA
group of 66-70 years, 4 patients (i.e.26.66%) were in the age group of 56-60 years, 3
patients (i.e.20%) were in 61-65 years age groups and 2 patients (i.e.13.33%) were in 50-
years age group, 4 patients (i.e.26.66%) were in 61-65 years age group and 2 patients
were (i.e.13.33%) were in 56-60 age groups and where as no patients were reported in
patients (i.e.13.33%) were in Muslim community and none of the patient observed in
only 1 patient (i.e.6.66%) was of Muslim community and none of the patient observed in
occupation, 3 patients each (i.e.20%) were in active and labor groups. No patient was
economic group, 5 patients (i.e.33.33%) were in to high class socio-economic group and
socio-economic group, 6 patients (i.e.40%) were in poor class socio-economic group and
(i.e.40%) were alcohol abusers and 4 patients each (i.e.26.66%) were habituated to tobacco
chewing.
(i.e.53.33%) were indulging in Nitya drita Prishtayana and 3 patients (i.e.20%) were
indulging in ativyavaya.
(i.e.26.66%) were habituated to Mutra nigraha and only 1 patient was indulging in
ativyavaya.
sleep, 5 patients (i.e.33.33%) were having sleep only in night hours, 4 patients
(i.e.26.66%) were having sound sleep and no patient was reported with the habit of
habit, 5 patients (i.e.33.33%) were having disturbed sleep, 4 patients (i.e.26.66%) were
habituated to sleep only in night hours and no patient was reported from Divaswapna.
(Day sleep)
and Samagni, 3 patients (i.e.20%) were having mandagni and no patient was reported
with teekshnagni.
5 patients (i.e.33.33%) were having Samagni, 2 patients (i.e.13.33%) were reported with
and 3 patients each (i.e.20%) were reported with Madhyama, Krura and Sama koshta.
4 patients (i.e.26.66%) has Madhyama koshta, 3 patients (i.e.20%) were of Krura koshta
patients (i.e.40%) were having frequent mala pravritti and only 1 patients (i.e.6.66%) was
pravritti, 4 patients (i.e.26.66%) were constipated and no patient was reported with
Colour 0 0 0 0
Odour 0 0 0 0
Quantity 0 0 0 0
Frequency of Urine was the one of the inclusion criteria for the patients. So all 30
Table No. 31. Showing distribution of patients by type of Desha. (Nature of Habitat).
Anupa 0 0 0 0
Sadharana 0 0 0 0
The place where this study was conducted is in Jangala pradesh. So all the
Vata 0 0 0 0
Pitta 0 0 0 0
Kapha 0 0 0 0
Pitta kapha 0 0 0 0
Sama 0 0 0 0
their constitution and no patient was reported with other doshik constitution.
Adhyashayana 3 20 3 20
Ajeerna 3 20 3 20
VIHARAJA NIDANA
Vyayama 9 60 13 86.66
ANYA
Anupa matsya sevana and Katu amla, Kashaya rasa pradhana ahara sevana. 3 patients
indulging in Rooksha ahara sevana, 8 patients (53.33%) were indulging in Anupa matsya
sevana, 7 patients (i.e.46.66%) were habituated to Katu, Amla, Kashaya rasa pradhana
ahara sevana and Kharjura, Shaluka, Kapitha, Jambu phala, 6 patients (i.e.40%) were
habituated to Rooksha Madhya sevana and 3 patients each (i.e.20%) were indulging in
Nitya dhrita pristayana, 4 patients (i.e.26.66%) were habituated to Vega sandharana and
Table No. 35. Showing the Prostate findings by Digital Rectal Examination. (DRE)
(i.e.73.33%) were noticed with median lobe enlargement, 4 patients (i.e.26.66%) were
mild enlargement and 6 patients (i.e.40%) were noticed with moderate enlargement of
prostate.
prostate was reached with difficulty, 5 patients (i.e.33.33%) were noticed with the easy
palpation of upper border of the prostate and no patient was reported with palpation of
consistency, 9 patients (i.e.40%) were noticed firm to hard consistency of prostate and no
Rectal mucosa – All patients the prostate was found free of rectal mucosa.
(i.e.66.66%) were noticed with median lobe enlargement, 5 (33.33%) noticed with border
mild enlargement of prostate and 5 patients (i.e.33.33%) were noticed with moderate
enlargement.
prostate was reached easily. In 7 patients (46.66%) the upper border of prostate was
reached with difficulty. No patient was reported with palpation of upper border of
prostate.
smooth consistency, 6 patients (i.e.40%) were noticed firm to hard consistence and no
Rectal mucosa – In all patients prostate was observed with free of rectal mucosa.
urine, 4 patients (i.e.26.66%) were observed with 101-200 cc Residual urine and no
urine, 2 patients (i.e.13.33%) were observed with 101-200 cc residual urine and no
All the assessment of subjective and objective parameters was made on the basis
Subjective Parameters
Table No.37. Showing Subjective parameters before and after treatment in Group-A
01 4 3 2 2 0 0 1 12 2 1 1 0 0 0 0 04
02 5 5 4 5 2 3 3 27 2 2 1 2 1 1 1 10
03 5 4 2 3 2 3 2 21 2 2 1 2 0 1 0 08
04 5 5 2 5 3 3 3 26 2 2 0 1 0 0 1 06
05 4 4 0 1 0 0 2 12 1 2 0 0 0 0 1 03
06 5 5 2 2 2 2 3 21 2 2 0 1 1 1 1 08
07 4 5 5 5 3 1 2 25 2 3 2 2 2 1 2 14
08 4 3 4 0 0 1 2 14 1 1 2 0 1 1 1 09
09 5 3 0 2 2 2 1 15 2 1 0 2 1 1 1 06
10 5 4 4 2 2 1 1 19 2 1 1 1 1 0 1 07
11 3 4 1 0 0 0 1 16 1 2 0 1 0 1 1 6
12 4 3 1 0 0 0 1 09 1 2 1 0 0 0 1 5
13 3 4 0 3 1 1 1 13 1 2 0 2 1 1 1 8
14 5 3 3 2 2 2 2 19 2 2 1 2 1 1 2 11
15 5 4 4 3 3 2 2 24 2 2 1 1 1 2 2 11
Total 66 59 32 38 24 23 28 25 27 11 17 10 11 16
BT AT BT AT BT AT BT AT BT AT
16 5498 5 3 1 0 3 2 3 2 1 1
17 0987 4 2 0 1 3 2 3 2 2 1
18 5331 3 2 0 0 1 0 1 0 0 0
19 5350 4 1 1 0 2 1 2 1 1 1
20 5424 4 2 0 0 0 0 0 0 0 0
21 0225 4 1 0 0 3 2 3 1 1 1
22 5306 3 2 0 0 2 1 2 1 1 0
23 3128 3 2 0 0 2 2 2 1 1 0
24 3631 5 2 1 1 3 2 3 2 1 1
25 3035 3 1 1 1 2 1 2 1 0 0
26 3641 2 1 0 0 1 1 1 1 0 0
27 3674 3 3 1 1 2 1 1 1 0 0
28 3692 4 3 0 0 1 0 1 1 1 0
29 0702 5 4 1 1 3 2 2 1 1 1
30 0704 4 2 0 0 2 1 2 1 1 1
16 4 3 3 2 2 2 2 18 2 2 2 2 2 1 2 13
17 5 5 4 5 2 3 3 27 2 2 2 3 1 2 2 14
18 5 5 0 2 0 0 3 15 3 4 0 1 0 0 1 09
19 5 4 0 2 2 2 2 17 3 2 0 1 0 1 1 08
20 5 4 0 0 0 1 2 12 4 3 0 0 0 1 2 08
21 4 5 3 2 2 2 2 20 3 2 3 2 2 2 2 16
22 5 5 0 2 3 3 3 21 3 3 0 2 2 2 2 14
23 5 4 3 3 3 2 2 22 3 3 1 1 2 2 2 14
24 4 4 4 3 3 2 2 22 2 2 1 3 3 1 2 14
25 4 2 3 2 1 1 1 14 2 1 2 1 1 1 1 09
26 3 3 0 0 0 0 1 07 1 2 0 0 0 0 1 04
27 5 4 3 1 1 1 1 16 3 2 2 1 1 1 1 11
28 4 4 3 2 1 1 1 16 3 3 2 1 1 1 1 13
29 5 3 3 4 3 3 2 23 2 1 2 2 3 3 2 15
30 4 4 3 2 0 1 1 15 3 2 2 1 0 0 1 9
Total 67 59 32 26 23 24 28 39 34 19 21 18 18 23
01 33 32 09 19 19
02 18 20 10 27 24
03 27 26 11 25 24
04 44 42 12 21 20
05 22 20 13 23 20
06 20 16 14 29 29
07 21 20 15 42 40
08 21 20
01 3 1 09 1 0
02 1 0 10 2 1
03 3 3 11 2 1
04 3 2 12 2 1
05 1 1 13 2 1
06 1 0 14 2 2
07 2 1 15 2 1
08 1 0
16 37 37 24 32 32
17 33 44 25 21 22
18 20 22 26 18 19
19 23 23 27 23 23
20 20 20 28 19 20
21 25 25 29 49 49
22 21 22 30 21 20
23 22 22
16 2 1 24 2 2
17 2 2 25 1 1
18 2 1 26 1 1
19 1 1 27 2 1
20 1 1 28 1 1
21 2 1 29 2 2
22 1 1 30 2 1
23 1 1
Subjective parameter
The overall effect of the therapy on the basis of subjective parameters was
indicates moderate response, 3 indicates good respond, and 0 indicates no response. The
percentage made by the base of total or maximum cumulative score i.e. 18. (3 scorings
into 6 symptoms). For objective parameters the maximum cumulative score is 15. (3
Table No . 49. Showing over all effect of I-PSS Index of Vatashtila ( BPH ).
EFFECT ON MALASANGA
EFFECT ON ANILASANGA
shown Poor response and only 1 patient (i.e.5.55%) reported with no response.
response, 10 patients (i.e.55.55%) has shown Poor response and 2 patients (i.e.11.11%)
EFFECT ON ADHMANA
Table No. 53. Showing over all effect of Ruja /Sashoolyukta Mutra tyaga.
response, 3 patients (i.e.16.66%) has shown Poor response and 6 patients (i.e.33.33%)
In Group B – Among 15 patients, 1 patient each (i.e.5.55%) has shown good and
moderate, 9 patients (i.e.50.44%) has shown poor response and 3 patients (i.e.16.66%)
Table No. 54. Showing over all effect of Ruja /Sashoolyukta mutra tyaga.
response, 5 patients (i.e.27.77%) has shown Poor response and 2 patients (i.e.11.11%)
response, 1 patient (i.e.5.55%) has shown poor response and 6 patients (i.e.33.33%) were
not responded.
SIZE OF PROSTATE
Table No. 55. Showing over all effect of size of the prostate.
UPPER BORDER
Table No. 56. Showing over all effect of upper border of the prostate.
RESIDUAL URINE
response, 1 patient (i.e.5.55%) has shown poor response and 6 patients (i.e.33.33%) were
not responded.
OVERALL RESULTS
The over all assessment is based on i.e. of cumulative values. Above 60% of the
cumulative score is considered as good response. Above 40% of the cumulative score is
poor response. Below 20% of the cumulative score is considered as not responded.
Table No. 60. Showing overall results of Subjective and Objective parameters in Group A.
treatment Matrabasti.
Table No. 61. Showing over all effect of Subjective and objective parameters in Group B.
15 patients under took for this study has shown good-00, moderate-2 (11.11%), poor-10
Statistical analysis of the Clinical and Functional Parameters and Inter group
Table No. 62. Showing the individual study of Group A.
Sl. Symptoms Mean score Mean S.D. S.E. t p value R
B.T. A.T. Net % value
eff. Relief
01 Incomplete 4.4 1.666 2.733 62.13 0.4576 0.118 23.16 <0.001 HS
emptying
02 Increased 3.933 1.8 2.133 53.23 0.639 1.165 12.486 <0.001 HS
frequency
03 Intermittency 2.133 0.733 1.466 65.63 1.2459 0.321 4.559 <0.001 HS
04 Urgency 2.533 1.133 1.466 55.27 1.2459 0.321 4.559 <0.001 HS
05 week stream 1.6 0.666 1.066 58.37 0.883 0.228 4.674 <0.001 HS
06 Straining 1.533 0.733 0.8 52.18 0.941 0.242 3.292 <0.001 HS
07 Nocturia 1.866 1.066 0.733 42.87 0.883 0.228 3.214 <0.002 HS
Table No. 63. Showing the individual study of Group B.
Table No. 64. Showing the inter group comparison. (A.U.A) Symptom score index.
Table No. 65 Showing the individual study of (Mala, Mutra, Anilasanga ,Adhmana,
Table No-67 Showing the inter group Comparative effect of (Mala, Mutra,
Group A.
group-B
When the two groups are compared, except in the parameter incomplete emptying
rest of the parameters shows non-significant i.e. the mean effect incomplete emptying is
not same in the two groups after the treatment (p<0.05 ). But individually the
performance of Group A is more effective in the all the parameters (by comparing p
value). The parameter incomplete emptying, urgency, straining, and nocturia, shows
more significant in Group A than in Group B (by comparing t value). The parameter
weak stream shows non-significant in Group B (p>0.05). In Group B, the mean effect
after the treatment is more than Group A, but the in Group A the variation of the S.D is
very less in the parameter. There is uniform effect in all the parameter on the patient. We
can also observe the mean net effect of Group A is more than Group B before and after
the treatment. Hence, Group A is more effective (by comparing mean, variance, and co-
efficient of variation.)
tyaga, shows not-significant. When the mean effect of the two groups. But, the individual
groups shows significance in the above said parameters. The but the objective parameters
weight of the prostate and residual urine shows non-significant in the mean effect of the
two groups after the treatment individually the Group A shows more significant than
Group B in the parameter of weight of the prostate and residual urine, but the parameter
impart his knowledge to other members and the desire to record the life and needs.
Because of these characteristics, lots of inventions have been enlightened in the field of
are universally applicable to each individual’s daily existence. Ayurveda speaks of every
element and facet of human life, offering guidance that who seeks greater harmony,
Ashtila is the hard, round, stony structure. Acharya Sushruta explained very
clearly about its structure and location in the body. It is located in Shakrunmarga i.e. in
between Guda and Basti pradesha. Acharya has explained different types of anatomical
structures with lot of similes for the Ashtila which are elaborated in literary part.
“Ashtilavat Ghana Granthi”, which leads to Mala, Mutra, Aanilasanga and Adhmana, etc
is seen.
138 Discussion
VATASHTILA vis-à-vis PROSTATE
It is one of the great job being an Ayurvedist, with regards to find the description
of prostate gland and the interpretation of its related explantion in Ayurveda. There is no
direct reference regarding this entity in the existent Ayurvedic literature. There by it is
our prime duty to give an appropriate conclusion related to prostate gland in Ayurvedic
terms.
But some scholars concluded that Basti shiras as prostate gland. Where as
Dalhanas comments on Su. Ni. 3\5 and emphasis as “Basti Shiraha Mutrashayopari
Tanobagaha”. It means basti shiras lies in the upper part of the bladder.
As our Acharyas dealt even about the minute structures of the body, no doubt they
may have mentioned about the prostate. Acharya Sushruta mentioned about the organs,
which lies around the Basti, while explaining Mutra utpatti, he emphasized on location of
the Basti, and mentioned the terms like Pourusham, Vrishanou and Guda. (Su. Ni 3\19).
Here, Pourusha can be safely concluded as prostate because, many scholars and
authors have followed the same view. Following are the some of the references –
Delhi)
Sena.
139 Discussion
Acharya Sushruta while explaining the location of Vatashtila, mentioned the
terms like “Shakrun Marga” on this regard Dalhana comments that Guda and Basti as
“Shakrun Marga” and in this place Vatashtila is situated which is “Deergha Varthula
Akara,”. within this area there is no other organ which is “Deergha Varthula Akara,”
other than prostate. By this we can concluded that Vatashtila is none other than prostate
which is situated in the inferior aspect of the bladder. (Located at the point at which the
Mutra praseka
There is no direct reference regarding the length of Mutra praseka but with the
help of Uttara Basti netra pramana it can be summed that, the length of Mutra praseka in
males is 6 - 7 angula.
Pourusha
Shukravaha Nadi which extends from Vrushana and opens in Mutra praseka just 2 angula
below Bastidwara then we can infer that probably Acharyas were included such an organ
in between Medhra mula pradesha and Basti dwara, which resembles that of Prostate
gland but. Pourusha Granthi the term already considered as a prostate gland by some
experts. I too agree with that “Pourusha” can be correlated with prostate, but when it
turns to Benign Prostate Hyperplasia it can be correlate with Vatashtila on the basis of
140 Discussion
Prostate
The function of prostate and its vulnerabilities arise from its place in male
anatomy. The prostate is a walnut sized chestnut shaped gland which is strategically
located at the point at which the bladder gives rise to the urethra, the outlet for urine. In
an adult male, the prostate usually weighs about 20 grams. Almost all of this mass
The prostate literally doubles in size during puberty. In some of the men prostate
never changes in size. But, unfortunately 60% of elder population (i.e. age group of 50-60
years) is in progressive stage of BPH. Usually this remains asymptomatic till the age of
50, by the age of 80, however 90% of men suffer from one or more symptoms of BPH.
Female Prostate
The term some times applied to the periurethral glands in the upper part of urethra
in the female. This is from “Stadman’s Dictionary” But it cannot be taken into
NIDANA
In our classics Vardhakyajanita rogas are mentioned along with their preventive
of our body is under the control of Vata and it is responsible for Arogya and Anarogyata
intern causes Dhatukshaya. Persistent nidana sevana makes the Prakupita vata to attain
Prasaradi avasthas.
Vatasthila is one of the Vatadosha pradana vyadhi. Vriddhavastha may be the one
partial or complete obstruction of urine and constipation, etc generally follows with old
age.
141 Discussion
AHARAJA NIDANA
psychotropic drugs causes LUTS and BPH. In one or the other aspect they disturb the
guna.
Madhura, Pavana nashaka. It is responsible for excessive Kledatva in Dosha, Dhatu, Mala
and Srotas. Thus, producing favorable conditions in the body for various diseases
Adhyashana. Due to this Ajeerna and Agnimandya takes place and ultimately resulting
into Ama formation. Further it can result into the formation of unmetabolized end
products and reaches to Mutravaha srotas, where they cause different Mutra rogas
including Vatashtila.
142 Discussion
VIHARAJA NIDANA
Mutravega sandarana
voluntary suppression of the urge of micturition if a person indulges for a long period of
time. This brings about vitiation of Vata to the extent that it results in Vatashtila. The
concept of Vata is analogus to that of nervous system in its functional aspect and is
presented in the study with respect to reflex mechanisms and functioning of the bladder.
The bladder is influenced by conditions that alter the membrane threshold and can
the propensity for spontaneous activity contributes in part to detrusor muscle instability
biophysical properties of body cells. Aggravated vata due to its suppression infiltrates
inside the Sushira Snayu, Sira and Dhamani of Basti and make them loose so that they
cannot contract during the urge of Mutra and thus urine cannot be voided out.
induces the mechanical pressure over the prostate and bladder and moreover those
persons tend to suppress the urge of urine there by vitiate Mutravaha Srotas. During the
intercourse (Mutritasya Udaka, Bhakshya) it may loosen the bladder sphincter and
143 Discussion
Ati vyayama , chankramana, and baravahana
Excessive Vyayamadi leads Datu, Ojah khsaya, because one should have do half
of his body strength other voice it will Vataprakopa result of Datu-kshaya etc.
house, the person is likely to suffer from dysuria, it is very difficult to correlate this
adipose tissue is the main source of aromatization of testosterone to estrogen and this
estrogen is abundantly found in hyperplastic prostatic cells. Hence obese persons are
more risky to develop BPH. Beef, higher milk consumption and lower consumption of
green and yellow vegetables, NIDDM, Hypertension, Tallness, Obesity, and high insulin
and low HDL cholesterol levels are risk factors for BPH. The etiological factors of BPH
are uncertain even though intense research on various histological, hormonal and age
growth factors and neurotransmitters may play a role, either singly or in combination, in
thereafter, and the rate of decrease sharpens by about age 50. This in some ways is the
male equivalent of menopause. The decline in testosterone production typically calls into
play the compensatory release of other hormones, which are stimulants to testosterone
144 Discussion
production. These cannot prevent the decline in testosterone levels, but they can lead to
to the increased binding and/or to the decreased clearance of DHT from prostate
cells. This reminds us about the Acharya's view about the depletion in the Shukra dhatu
the etiological factors but it is need of the hour to explore these factors with justifiable
In this clinical trial most of the patients had given the history of Mutravega
dharana, Constipation, Teekshna ahara, Nitya Druta Prushta Yana. Some patients have
Age factor and Nidana are the causes for the deformity (i.e.Khavaigunya) and
restrain Shaithilya in the structures of Basti i.e. Sira, Snayu and Mansa and at another
facet it aggravates Vata dosha. This aggravated Vayu i.e. Apanavayu settles in vitiated
structures of Guda and Basti and interacts with them. Finally the obstruction occurs by
manifestation of lakshanas.
bladder and the rectum, giving rise to obstruction to urine, feces, and flatus. It is
important to note that, a stony hard mass is found in the carcinoma of prostate. As per my
hypothesis Vatashtila is not having hard consistency. But, in early stage it soft in future
145 Discussion
SYMPTOMS
Urgency, Weak stream, Staring Nocturia are the symptoms found in Vatashtila.
BPH mainly consists with the symptoms like incomplete emptying, increased
frequency, intermittency, weak stream, staining, and Nocturia. Hence, there is much
similarity in symptomatology of BPH & Vatashtila. The other symptoms like Adhmana,
changes in both bladder function and nervous system function, lead to urinary frequency,
used to treat Mutraghata. Avapeedaka sneha prayoga, Snigdha virechana, Trividha basti,
Avagaha Swedana, etc are explained. Rasayana and Vajeekara treatments are indicated.
Prostate belongs to reproductive system. There is decrease in androgen level leads to the
proliferation of stromal and epithelial cells of the prostate. Shatavari, Gokshuru, Shilajatu
are some of the drugs which are extensively explained in the management of Mutraghata
that suggests the role of Vrishya and Rasayana drugs. Trivanga is also very useful. Food
is the main cause for both 'ease' and 'disease'. These foodstuffs need proper conversion
(Agni) to their elemental form for nourishment of dhatus for which a media is required
which is called as Srotas. Pathya is that one which is wholesome to body and Apathya is
146 Discussion
MODERN LINE OF MANAGEMENT
insufficiency, Preventing future episodes of gross haematuria, Urinary tract infection, and
Urinary retention.
suppression, aromatase inhibitors, and plant extracts, which are also reviewed. Because
these agents are widely used in some parts of the world despite the lack of properly
designed clinical trials. Because plant extracts are not classified as drugs, the marketing
The enthusiasm for medical therapy has been supported in part by the limitations
consistently achieve a successful outcome, necessity for re-treatment, and the suggestion
that prostatectomy increase the risk of delayed life-threatening cardiac events (Lepor,
1993). Because the indication for intervention in the overwhelming majority of patients
with BPH is to improve quality of life by reliving symptoms (Mebust et al, 1989), the
treatment decisions.
Srotas and particularly of Basti, removes the Sanga (Obstruction), Reducing the Vriddhi,
Protects the Basti marma and makes proper flow of Urine, following proper diet and
regimens may be the 10 principle to manage the Vatashtila (BPH). These principles
147 Discussion
DISCUSSION ON CLINICAL STUDY
The patients were selected from the medical camps conducted in the premises of
patients were diagnosed and selected for the clinical study between the age groups 50 to
All the patients for the study are randomly selected and categorized in to two
groups. In Group A Matrabasti and Shamana Snehapana in Group B the yoga selected is
Sukumara Kumara Ghrita i.e. for both groups. Matrabasti with 70 ml of Sukumara
Kumara Ghrita was given for 8 days and 16 days was for follow up, where as for
Shamana Snehapana 16 days with same Ghrita was given and 8 days follow up. Total 24
DISCUSSION ON OBSERVATIONS
Age – Higher incidence of BPH was found in the age group of 66–70 years (15
(i.e.20%) were belonging to the 56-60 years of age group and remaining 2 patients
This reveals that the disease, which afflicts the aged males, supports the view of
androgen metabolism. Age play an important role in the manifestation of BPH and
according to Ayurveda, Vata dominates in this period and hence elders are more likely to
community.
148 Discussion
This reflects the geographical preponderance of this particular region rather than
Occupation – The equal incidence of occupation observed during this study. This
shows that the Vatashtila (BPH) patients are obtained from those vicinity of works where
they tend to suppress the urge of micturition or continuously sitting in one place as well.
diagnosis of BPH in men with higher milk consumption and lower consumption of green
and yellow vegetables. Overall, there is no convincing evidence for any dietic factors to
Vyasana – More incidence of the disease was found in the patients with Tea or
Coffee addiction (12 patients i.e.80%). Followed with smokers (12 patients i.e.40%). 9
patients (i.e.30%) were alcohol abusers and 6 patients (i.e.26.66%) were habituated to
Tobacco chewing.
both testosterone and estrogen levels. Alcohol is also the causative factors for BPH by
increasing the plasma testosterone level (Chopra et al, 1973). However in this study all
most all patients were found with habituated to some of habits. Because of small sample
size and stipulated nature of study definite relation of habits can not be taken out.
habituated in Nitya drita pristayana and 4 patients (i.e.20%) were indulging Ativyavaya.
149 Discussion
Vata is the nearest cause for Vatashtila and the present study supports the view.
Because of most of the patients were indulging in Ashukari vata vridhhikara bhavas like
and biophysical properties of body cells. Nitya Drutaprushta Yana (Continuously sitting
and traveling over vehicles and horses, etc) leads to fatigue and exertion thus vitiates
Vata. Indulging in Ativyayama and Ativyavaya leads to dhatu kshaya and extreme
vitiation of Vata. Ekman suggested that the increase in the fibromuscular stroma is a
result of sexual activity (Ekman,1989). The decrease in sexual ability and frequency of
sexual activity with advancing age, exactly when the prevalence of BPH increases, in fact
function (Altwein and Keuler, 1992). These are all the favorable conditions for the
Vatashtila. (BPH)
(i.e.33.33%) were having sound sleep, 9 patients (i.e.30%) patients were habituated to
sleep only at night hours and no patient was accustomed to day sleep.
Nidra Ardha Rogahari, Kshudha Sarva Roga Hari | This famous quotation was
well appreciated in this study. Disturbed sleep habits hampers the metabolic processes
and intern causes dhatukshaya and ultimately results in Vatavriddhi. Apart form this the
majority of the patients were of old age group, hence because of this the sleep habitat is
already affected.
150 Discussion
Sarve Roga Api Mandagni Eva Karanam | The famous quotation form Charaka
has been well appreciated in present clinical study. Decreased and disturbed nature of
Jathargni indicates that the patients are having pre-existed state of vikrita doshas and
malformation of dhatus. Dhatu kshaya strongly reflects in terms of Vata dosha vriddhi.
Vriddhavastha and vikrita avastha of Jathargni makes the more favorable place for
Vatashtila.
(i.e.16.66%) patients were having normal bowel movements and only 1 patient
(i.e.3.33%) was having irregular bowel habits. Frequency of Mutra is the criteria for
Due to disturbed pattern of mala pravritti shows the pre-existence of vikrit vayu
and it may be due to more enlarged prostate, which causes obstruction to feces.
This suggests that incidence of BPH may be high in these Prakruti purushas and which
Chief Complaints
The maximum symptoms were present in the age group of 66 to 70 age group and
men over 50 years of age. Approximately the incidence of BPH is more in fifth decade of
men’s life.
151 Discussion
Prostatic findings – The present clinical study assessed through DRE. Most of
the patients were having median lobe enlargement and border line enlargement and free
to 100 cc of residual urine. 2 patients (i.e.20%) were having 101-200 cc of residual urine.
Whereas, no patient was observed with residual urine above 201 cc.
This is due to fatigue of the altered detrusor during prolonged voiding at higher
than normal pressures and reduced flow. Towards the end of the urination, the detrusor
can no longer maintain sufficient contraction to force the urine, to keep the bladder neck
and prostatic urethra open. Due to the contraction and leaving residual urine in the
In the present clinical study it was observed that, size and weight of the prostate is
DISCUSSION ON RESULTS
The results were assessed on the basis of subjective and objective parameters with
Subjective Parameter
Group A – The AUA or I-PSS is having 7 symptoms, all the seven symptoms
were given according to age interval. In the age interval of 50 to 55, among two patients
in one patient observed good response and one patient was poor respond. Where as 56 to
60 age interval among 4 patients, all three patient were observed poor respond. And age
61 to 65 among 3 patients, one patient was not responded, where in rest of two patients
responded poorly. As the age interval of 66 to 70, among 6 patients in only 2 patients has
152 Discussion
Group B – In the age interval of 50 to 55, there was no any patients were
reported. Where as 56 to 60 age interval among 2 patients, only one patient was observed
good response and another 1 was patient not responded. And age 61 to 65 among 4
patients one patient was not responded, where in rest of 3 patients responded poorly. Age
interval of 66 to 70, among 6 patients in 3 patients has seen poor respond remaining 3
EFFECT ON MALASANGA
Group A – Malasanga was found 2 patients in the age interval of 50 to 55, and
shown good response. 4 patients were in age interval of 56 to 60 years. Among these, 3
patients shown good response and 1 patient was not responded. 3 patients were observed
in the age group of 61 to 65 years. All has shown good response. 4 patients were in the
age interval of 66 to 70 years. Among 6 these 4 patients has shown good response,
patients were in age interval of 56 to 60 years. Among these 1 patient has shown good
response and another patient was not responded. 4 patients were in the age interval of 61
to 65 years. Among these 2 patients responded good and remaining patients were
responded moderately and poorly respectively. 6 patients were in the age interval of 66 to
70 years. Among these 3 patients each has shown moderate and poor response
respectively.
153 Discussion
EFFECT ON MUTRASANGA
Note : - In Group A, 8 patients were having this symptoms and in Group B, 6 patients
were having this symptoms.
Group A – The symptom Mutrasanga in the age interval of 50 to 55, one patient
observed and shown good response. In the age interval of 56 to 60, among 2 patients both
patients shown good respond. In age interval 61 to 65 in among 2 patients one patient
was observed very good response and 1, patient was not responded. As interval of 66 to
70, among 3 patients, 2 patients has seen good responded, one was not responded.
Group B – In the age interval of 50 to 55, there was no any patients are reported.
In the age interval of 56 to 60, among 2 patients, only one patient shown good response,
and another patient was not responded. In the age interval of 61 to 65, among 4 patients 1
patient was responded poorly, and rest of the patients were not responded. In rest other
one patient was responded good, and another one was moderately responded. In the age
interval of 56 to 60, among 4 patients, 3 patients shown good response and 1 patient was
not responded. In the age interval of 61 to 65 in 2 patients 1 was moderately and 1 was
poorly responded. In the age interval of 66 to 70, among 6 patients in 3 patients has seen
good respond, 2 patients were moderately responded and 1 patient was not responded.
the age interval of 56 to 60 interval among 2 patients, both patient has shown poor
response. In the age interval of 61 to 65, among 4 patients all patients responded poorly.
In the age interval of 66 to 70, among 8 patients in 1 patients has seen good respond, 5
154 Discussion
EFFECT ON ADHMANA
Note : - In Group B, among 15 patients 14 patients
In Group A – Symptom Adhmana in the age interval of 50 to 55, among 2
patients each patient has shown good and poorly response. In the age interval of 56 to 60,
among 4 patients, 2 patients has shown good response and 2 patients are poorly
responded and in the age interval of 61 to 65, 2 patients responded poorly. In the age
interval of 66 to 70, among 6 patients 2 patients has shown good response and 1 patients
has seen moderate respond and 2 patients were poorly responded and only 1 patient was
not responded.
Group B – In the age interval of 50 to 55, there was no any patients are reported.
In the age interval of 56 to 60, among 2 patients each patient has shown poor and
moderate response. In the age interval of 61 to 65, among 4 patients 3 patients were
poorly responded, 1 patient has shown good response. In the age interval of 66 to 70,
among 8 patients in 5 patients are poorly responded and 3 patients were not responded.
Note : - In Group A, 11 patients were having this symptoms and in Group B, 10 patients
were having this symptoms.
Group A – The Symptom Ruja / Sashoolyukta mutra tyaga, in the age interval of 50
to 55, 1 patient observed and shown good response. In the age interval of 56 to 60, among
3 patients 2 were patients observed good response and 1 was poorly responded. In the age
interval of 61 to 65, among 2 patients 1 patient was observed good response and 1 patient
was poorly responded. As interval of 66 to 70, among 5 patients in 3 patient has shown
Group B – In the age interval of 50 to 55, there is no any patients are reported. In
the age interval of 56 to 60, among 2 patients, both are not responded. Where age 61 to
65, among 2 patients no one has responded, In the age interval of 66 to 70, among 6
patients 3 patients were good responded and 1 is poorly responded rest of other 2 patients
155 Discussion
OBJECTIVE PARAMETER
SIZE OF PROSTATE
Group A – There was no response observed except age interval of 66 to 70, only
UPPER BORDER
MOBILITY
RESIDUAL URINE
In Group A – In the age interval of 50 to 55, among 3 patients only 1 patient was
responded moderately and 2 patients were not responded. In the age interval of 56 to 60,
among 4 patients, 1 patient has responded good, 2 patients were poorly respond and 1
patient was not responded. In the age interval of 61to 65, among 3 patient 1 patient was
responded good, 2 patients were poorly responded. In the age interval of 66 to 70, among
60, among 3 patients 1 patient was responded good. In the age interval of 61to 65 among
5 patients 2 patient were responded and 2 patients were not responded. In the age interval
of 66 to 70, among 7 patients only 1 patient poorly responded, remaining all patients
156 Discussion
WEIGHT OF PROSTATE
In Group A – In the age interval of 50 to 55, among 2 patients only 1 patient was
responded moderately and 1 patients was not responded. In the age interval of 56 to 60,
among 4 patients 1 patient responded good, 3 patients were poorly respond. In the age
moderately responded. In the age interval of 66 to 70, among 4 patients, 2 patients each
STATISTICAL DISCUSSION
bladder was significant i.e. the mean effect of incomplete emptying is not same in the two
groups after the treatment (i.e. p value is <0.05). But individually the performance of
Group A is more effective in the all the parameters (by comparing p values). The
parameters incomplete emptying, urgency, straining, and nocturia, were more significant
in Group A then Group B (by comparing t value). The parameter weak stream was not
significant in Group B (i.e. p value is >0.05). In Group B, the mean effect after the
treatment is more than Group A, but in the Group A the variation or the S.D. is very less
in all the parameters. There is no uniform effect in the all the parameter of both Groups.
We can also observe the mean net effect of Group A is more than Group B before and
after the treatment. Hence, Group A is more effective, (by comparing mean, variance, and
co-efficient of variation).
157 Discussion
In the subjective parameter except Malasanga and Anilasanga shows not-
significant. When the mean effect of the two groups, but the objective parameters weight
of the prostate and residual urine shows non-significant in the mean effect of the two
groups after the treatment individually the Group A shows more significant then Group B
in the parameter of weight of the prostate and residual urine, but the parameter weight of
parameters after recording the baseline pre and post treatment data of Mala, Mutra,
Sukumara Kumaraka Ghrita has been selected for the clinical study because of the
direct indication of the yoga towards Mutrakricchra in the textbook of Chakradutta and
Bhaishajya ratnavali.
and Atibala are having properties like Mutrala, Mutrakricchrahara, Ashmari bhedana,
good Vedana sthapaka, normalizes the obstructed Gati of Vata dosha by other Dosha or
158 Discussion
Shatavari, Bala, Ashwagandha, and Ghrita are having properties like Mutrala,
Shoolahara.
enhances the absorption rate and alleviates Vatadosha. Eranda taila is Mridu virechaka
and Vatanulomaka. The name itself indicates, it is recommended for Sukumaras viz. old
activity and reduction in the weight of the testosterone induced prostate. It is also noticed
that it inhibits the stromal proliferation and controls the epithelial height. (Sundaram. R,
and Co; R&D Centre; The Himalaya Drug Co. Bangalore, 1999). It is one of the safe and
checks the proliferation of prostatic cells. It is Mutrala hence reduces residual urine. Its
Rasayana property increases the stability of Basti and Mutravaha srotas. Madhura rasa
and Vipaka, Sheeta veerya alleviates Pittadosha hence useful in burning micturition.
and Shoola etc. It is the best vatahara. (i.e. Apanavata) It can be claimed that it helps in
159 Discussion
The role of Phytotherapy in BPH
Some of the research scholars did their works with Phytotherapy in which they
about 1990. (Lowe and Fagelman,1990) Previously, these agents were popular in Europe,
particularly in France and Germany where they are often prescribed and their costs
The composition of plant extracts is very complex. They contain a wide variety of
chemical compounds, which include phytostosterols, plant oils, fatty acids, and
phytoestrogens, which of these is the exact “active” component is not definitely known.
Both the free fatty acids and the sitosterols have been thought to be the active
components.
160 Discussion
Table No.-72. Showing Components of Plant Extracts:
Mechanisms of action
The phytotherapeutic agents are generally unknown. (Dreikorn et al, 1998) Many
in vitro experimental studies have been undertaken to elucidate this. Thus, there are
numerous proposed mechanisms of action. The three mechanisms of action that have
received the greatest attention are anti-inflammatory effects, 5α-reductase inhibition, and
enzymes (Bach, 1982: Buck, 1996). Flavone, a phytoestrogen commonly found in plants
and herbs.
repens is as an 5α-reductase inhibitor. (Losker and Brogden, 1996) The human prostate
contains both type 1and predominantly type 2 isoforms of the 5alpha-reductase enzyme,
which catalyzes the conversion of testosterone to DHT (Rhodes et al, 1993: Span et al,
1999) DHT is important for the development of BPH. Decreasing DHT with the use of
161 Discussion
Growth factor alteration – These are also thought to act by altering growth
The treatment given to Group A i.e. Matrabasti patients with Sthanika mridu
abhyanga with Murcchita Tila taila and Sthanika swedana was done prior to Matrabasti.
Patient was advised to take alpa ahara before Matrabasti karma. The procedure is
complications were observed in all the patients during and after the Matrabasti procedure.
was up to 5 to 9 hours and in 2 patients it was retained for 2 to3 hours. Basti pranidhana
and Pratyagamana kala were recorded properly. During the course of therapy some
patients showed improvement in both obstructive and irritative symptoms i.e. incomplete
emptying of the bladder, increased frequency and urgency. Some patients showed marked
improvement during and after the treatment which was recorded in proforma of I-PSS
Index. Other symptoms like Constipation, were relieved in most of the patients. Addition
to that patients were relived from Durbalata and body aches, attained Indriya prasannata,
Chaitannya, even.
162 Discussion
Mode of Action Matrabasti
especially the Apanavata, which being sheltered in the Basti and Medhra leads to
Matrabasti is best treatment for old age persons, because of its less dose and
the Vata, as the disease Vatashtila is vata pradana vyadhi (Apanavata). Apanavata is
prime cause for the disease, as Moola of Vata is Pakvashaya (apanavata) the Sanchara
administered Basti dravya stays in pakvashaya and it will reach to the affected area
The Srotases of a Ruksha and Klanta persons (old aged Vatapradhana person) are
emaciated therefore there will be natural obstructio and n to the movement of Vata to
bring about normal functions. As explained earlier, the Sneha brings about
Srotomardavatwa and Vatashamana actions thereby causes Srotoprasadana and helps for
163 Discussion
From the foregoing description it may be inferred that on per-rectal
administration, the medicaments are absorbed through the villi of the rectal mucosa and
then come into the vein and then into circulation after proper metabolism. This rectal
route is also mentioned in allopathic system of medicine as the important systemic route
of administration for some drug in the form of retention enema. Drugs, absorbed into
external haemorrhoidal veins (about 50%), bypass the liver, while the drugs, absorbed
may acts locally or systemically after absorption of active principles from Basti dravya.
Guda is pradhana marma and the moola of Siras, that nourishes the body.
The rectum has rich blood supply and drugs can cross the rectal mucosa like other
lipid membranes. Thus unionized and lipid soluble substances are readily absorbed from
the rectum and from rectal venous plexus. The concentration gradient of Basti dravya is
more inside the lumen of intestine as compared to rectal venous plexus, which facilitates
the absorption. This rectal venous plexus further divided into internal venous plexus and
external venous plexus. Internal venous plexus, situated in the submocosal layer of anal
canal and carries into superior rectal vein and to external venous plexus.
Basti dravya is also absorbed from external venous plexus in three parts, i.e. in
lower part through inferior rectal veins and drained into internal pudendal vein, in middle
part through middle rectal vein which is having tributaries, those drains from bladder,
prostate and seminal vesicle into internal iliac vein, in upper part through superior rectal
164 Discussion
Basti dravya is also absorbed from the upper rectal mucosa, and is carried by the
Superior mesenteric vein into the portal circulation and enters into Liver. Secondly, the
portion absorbed from the lower rectum enters directly into systemic circulation via
middle and inferior hemorrhoidal veins. This indicates that due to more vascularity in this
area absorption rate is high. Acharyas also said that Guda (Uttara Guda) is the moola of
Sira.
From above it is clear that Basti dravya is absorbed through rectal mucosa either
by chemically altered or un-altered and carried throughout the general circulation and
gives systemic effect along with local effects like Vatanulomana, Mutravirajaneeya and
Shoolahara, etc. The ingredients of Sukumara Kumaraka Ghrita acts on Rakta dhatu
and helps to provide proper nourishment to Sira, Snayu as they are its Upadhatu. Ushna
Basti mainly acts on Pakvashaya the Mula sthana of Vata, it subsides vitiated
Vata, By means of its Katu vipaka, Ushna veerya it reduces the size and volume of the
Basti dravya posses Basti vishodhana drugs, it improves the stability and also
compliance of detrusor muscle of the bladder. When Basti dravya reaches in general
controlling leutenising hormone to stimulate Leydig’s cells present in testes and may
reduce the more production or more conversion of testosterone into DHT by inhibiting 5-
165 Discussion
By these factors Basti is responsible for the relief in the signs and symptoms of
the disease. So these observations suggests that this therapy not only attains symptomatic
nervous system related to the prostate (Apanavayu) and brings the normal function of the
bladder function, compounded by age related changes in both bladder and nervous
system, leads to urinary frequency, urgency, and nocturia, which are the most bothersome
BPH related complaints. Matrabasti may act on nervous system (Apanavayu related), and
Vatashtila (BPH) as the present clinical work reveals not only symptomatic relief but
there is also reduction in size and weight of prostate and decrease in the residual urine
166 Discussion
Observations of Shamana Snehapana Procedure
Group-B was taken for Shamana Snehapana. Patients were advised to take, mridu
bhojana, before night prior to Shamana snehapana. Which is to be taken when the patient
gets hunger i.e. “Anannaha” (morning Tiffin time). Patients were advised to take 15ml of
Sukumarakumara ghrita with Ushnajala as Anupana twice daily for 16th day followed by
The patients asked to report on 24th day counting from the day of commencement
complaints during and after the course of therapy, which was recorded as per proforma of
I-PSS Index. Other symptoms like Constipation were relieved in most of the patients. In
addition to that, patients were relived from Agnimandya, Durbalata, body aches and
Koshta, Shakha, Sandhi, Marmas quickly. (Ch. Su 13., A.Hr.Su.16/19) Its effect depends
upon the basis of method of administration and ingredients of the dravya being used.
“Anannaha” means without food, when patient is having hunger. In this condition Shrotas
will not be enveloped with kapha, and Sneha will get digested completely, as the
digestive enzymes are strong when the person is in hunger. And spreads all over the body
167 Discussion
The ingredients of the ghrita.-viz Dashamoola, Laghupanchamoola, Punarnava,
and Shatavari etc, are having Snigdha Guna it alleviates Vata Dosha. Gokshuru is
Shreshtha Mutrakricchra hara dravya and it makes Anulomana of Apanavata. By
considering above properties of ingredients it makes Anulomana of Apanavayu, remove
the Sanga, makes to facilitate to void the urine and stool properly, gives relief in burning
micturition, and emptying the residual urine in bladder. It also makes Basti Shodhana
hence stability of Snayu and Sira of Basti were maintained or reverses the pathology of
Vatashtila BPH. Rasayana property of these drugs generally enhances the normal
integrity of Mutravaha Srotas in particularly of Basti Gata – Sira and Snayu. It is having
5-alpha reductase enzyme inhibitory properties. It healps to reduce the weight or volume
of the Prostate. Snigdha Guna alleviates Vata Dosha. Ushna veerya alleviates both Vata
and Kapha. Laghu and Sara Guna increases Sara Guna of Mutra there by facilitate easy
voiding. Deepana-Pachana property improves Agni and digests Ama at Koshtha level.
and at Mutravaha Srotas level. Shodhana properties cleanse the Srotas and make it clear
for the proper movement of Apanavayu and leads to normal evacuation of bladder.
Shamana snehapana is indicated in Gulma, Mutrakrichra, Ghadavachras, etc, as the
Ghrita is the best Rasayana Agnideepana, vatahara, etc it helps in correcting the
pathology of Vatashtila (BPH).
Besides the above the Shamana ghrita, used in this study, also possess their
effects on smooth muscle contraction. Prasad et al (1966), reported that Varuna extract
increase the tonicity of smooth muscle of ileum, trachea and uterus in experimental
models. They concluded that the tonic effect of drug may be due to action on the
cholenergic receptors in the smooth muscles. So, a likely probability is that the drug may
be effective in increasing the contractility of detrusor muscle. Chopra et al (1970) also
reported that Varuna is efficacious in neuro-muscular hypotonic and atonic condition of
the urinary bladder.
As seen in the modern texts, the estrogens- metabolized (conjugated) in the liver
reaches the intestines where they are broken down by microorganisms and reabsorbed as
active hormones through entero hepatic circulation. The disturbance of liver function or
intestinal flora can thus alter this mechanism.
168 Discussion
Graph No. 01. Showing distribution of patients by age groups in both groups.
10 9
8 6
No. of Pt.'s 6
4 4
4 3
2 2
2 0
0
50-55 56-60 61-65 66-70
Age Groups
Group A Group B
14
15 13
No. of Pt.'s
10
5
2
1
0 0 0 0
0
Hindu Muslim Christian Others
10 9
8 7 7
6
No. of Pt.'s
4 3 3
2 1
0 0
0
Sedentary Active Labor Others
Occupation
Group A Group B
Graph No. 04. Showing distribution of patients by socio-economic status in both groups.
8 7
6 6
No. of Pt.'s 6 5
4
4
2
2
0
Poor Middle Class Higher class
Graph No. 05. Showing distribution of patients by food habits in both groups.
12 10
10 8
No. of Pt.'s
8 7
6 5
4
2
0
Vegetarian Mixed
15 12
10
10
No. of Pt.'s
6
4 4 4
5 3
2
0
Smk Tbc Alc T/C
14 13 13
12
10 9
8
8
No. of Pt.'s
6 5
4
4 3
2 1
0
Vy a y Vy a v Dr it P Mu Ni
Graph No. 08. Showing distribution of patients by sleep habits in both groups.
8
6 6
5 5
No. of Pt.'s
6
4 4
4
2
0 0
0
Day Night Sound Disturbed
8 7
7 6 6
6 5
No. of Pt.'s
5
4 3
3 2
2 1
1 0
0
M.A. V.A. Tk.A. S.A.
7 6 6
6
No. of Pt.'s
5 4
4 3 3 3 3
3 2
2
1
0
Mr Ma Kr Sa
Graph No. 11. Showing distribution of patients by nature of bowel habits in both groups.
8 7 7
6
6
4 4
No. of Pt.'s
4
2 1 1
0
0
Re Ir Co Fr
Graph No. 12. Showing distribution of patients by age groups in both groups.
16 15 15
14
12
No. of Pt.'s
10
8
6
4
2 0 0 0 0 0 0
0
Cl Od Fr Qu
15 15
16
14
12
10
No. of Pt.s'
8
6
4
2 0 0 0 0
0
A nupa Sa dha r a na J ha nga l a
10
8 8
8 7 7
No. of Pt.'s
6
4
2
0 0 0 0 0 0 0 0 0 0
0
V P K VP VK PK S
14 13 13 13
12 11
10
9 9
No. of Pt.'s
10 8 8
8 7
6
6 5 5 5
4
4 3 33 33 3
2 1
00 00
0
A B C D E F G H I J K L M N P
Graph No. 17. Showing distribution of patients by residual urine in both groups.
8 7
7 6 6
6 5
No. of Pt.'s
5 4
4
3 2
2
1 0 0
0
10 to 50 cc 51 to 100 cc 101to 200 cc 201 & Above
9 8
8 7
7 6
No. of Pt.'s
6
5 4 4
4
3
2 1
1 0 0
0
Sub. P Obj. P.
GR MR PR NR Overall Response
Graph No. 19. Showing overall response in Group B.
Overall Result in Group B
16 15
14
12 10
No. of Pt.'s 10
8
6
4 3
2
2 0 0 0 0
0
Sub. P Obj. P.
GR MR PR NR Overall Response
CONCLUSION
The long-term exposure to drug induced adverse events and the prohibitive costs
are the primary limitations of prevention therapy.
As there are no clinical, biochemical, or genetic predictors of Vatashtila (BPH)
development or progression, every male is at risk.
A potential role of medical therapy is to prevent the development of Vatashtila
(BPH) or its progression.
The ability to identify those individuals who are predisposed to develop clinical
Vatashtila (BPH) refractory to medical therapy would provide a more compelling
rationale for prophylaxis.
Acute urinary retention is often considered as an absolute indication for medical
intervention, which is related to age, severity of symptoms, and size of prostate
gland. Because urinary retention is a relatively uncommon event, a study designed
to determine whether medical therapy prevents urinary retention would require
large number of patients followed for a long interval of time.
Aim of this therapy is to prevent a relapse of a second episode of urinary retention
after a successful voiding trial. To test the efficacy of the drug therapy for this
indication, patients successfully completing a voiding trial after an episode of
urinary retention would be randomized to active treatment.
The role of treatment for any disease process depends on the magnitude of the
clinical effect and the incidence and severity of treatment related morbidity.
As evident from the present clinical study Vatashtila (BPH) is an ailment of the
ageing male, and is with multifaceted etiology i.e. Vatakara- ahara, vihara, Nithya
Druta Prusta Yana (excess riding /traveling) Mutranigraha, Teekshna oushada and
habits are alcohol consuming, smoking, etc.
The digital rectal examination and neurological examination are done to detect
prostate or rectal malignancy, to evaluate anal sphincter tone, and to rule out any
neurological problems that may cause the presenting symptoms.
I PSS is an ideal instrument to grade baseline symptom severity, and is helpful to
assess the response to the therapy adopted. Which, as a parameter is useful to
168 Conclusion
detect symptom progression in those men managed by watchful waiting. It is not
only meant for the diagnosis of Vatashtila (BPH), but also helpful for the
assessment of a variety of lower urinary tract disorders (e.g. Infection, tumor,
neurogenic bladder disease) in both men and women.
The basic principles of Ayurveda affirms that, the humor Vata dominates with
age by its un unctuousness ( Rukshaguna ), manifestation of Vatashtila (BPH)
will be more. Vata pitta prakruti, Vata kapha prakruti persons are more
susceptible to Vatashtila (BPH) as per the observation of the present study, and
Muslim community is least effected, as these people are with mixed food habits
and when compared with Hindus the extent of dhatu kshaya is not so severe.
After the main treatment (Basti) the follow up the patients are asked to take
Varunnadi kashaya, Shilajatu vati.
It is interesting to detect a reference in “Stadmans Dictionary” regarding female
prostate, and explanation about Para urethral glands in female. asthis reference
makes us to think if any vitiation or derangement of the urethral glands by either
structurally or functionally, it can leads to diseases like urethritis, bulbo urethritis,
where as it is interesting to have thought then “Ashtila or pourusha granthi”
(prostate ) afflictation will take place in female too. In Ayurvedic classics there
is no explanation about female prostate as well as “Ashtila” it needs further
exploration by the scholars of the Ayurveda.
Phytotherapeutic products are also used in modern science’s those are plant
extracts, derived from either the roots, the seeds, the bark, or the fruits of various
plants used. The composition of plant extracts is very complex. They contain a
wide variety of chemical compounds, which include phytostosterols, plant oils,
fatty scids, and phyto-estrogens. which of these is the exact “active” component is
not definitely known. Both the free fatty acids and the sitosterols have been
thought to be the active components.
Statistical enumerations has shown, among all the parameters except incomplete
emptying, are non significant, i.e. comparative effect ( P= <0.05 ). Where as the
objective parameters i.e. weight of prostate, residual urine volume are non
significant, in the comparative effect of two groups. Over all observation of the
169 Conclusion
subjective and objective parameters before and after the treatment, It is evident
even though group-A (Matrabasti) is more significant comparing to group –B
(Shamana.), a satisfactory evaluation of the treatment is possible, if research is
designed with both Shodana and Shamana therapy combined together. And over
all the results observed during the study is encouraging but it needs further
adaptations, diagnostic techniques viz –Prostate specific antigen test, Transrectal
ultra sound, biopsy (to know benign or malignant changes so as to rule out the
malignancy) and hormonal ease, are the standard parameters for the diagnosis as
well as the assessment of Vatashtila (BPH). The taken samples, study duration
and selected criteria for present clinical study may not be sufficient enough for the
better evaluation and treatment of Vatashtila (BPH).
It is observed from this study that, Sukumarakumaraka Ghrita by virtue of its
Balya, Rasayana, Vatahara, Vedanashamaka properties is having a definite role in
the management of Vatashtila (BPH).
I believe that several factors such as aging, the hormonal milieu, nonurologic
diseases, and prostatic growth milieu, nonurologic diseases, and prostatic growth
affect bladder morphometry, neurologic innervations, BOO, and renal function,
and that these factors collectively contribute to clinical BPH. Our present
understanding of the pathophysicalogy of clinical BPH is rudimentary. It is,
therefore, imperative to develop a more comprehensive understanding of the
pathophysiology of symptoms. This knowledge will result in more effective use
of existing therapies and will provide the rationale for the next generation of
therapeutic modalities.
170 Conclusion
SUMMARY
1) Introduction.
2) Review of literature.
3) Methodology.
4) Results.
5) Discussion.
6) Conclusion.
Interest in diseases of Vatashtila (BPH) has always been considerable. In the last
two decades of the 20th century, the interest reached such levels that many important and
valuable studies into this field were carried out, but it was without question the changes
that took place in the treatment of Vatashtila (BPH) that made this work to proceed with
ideal interventional treatment for BPH. The very fact that in the name of “Ashtila or
Pourusha granthi (prostate gland)” has been dealt in such details, in our texts proves
the importance and antiquity of this study. Various measurements for its management
have been advised which only highlights the extent to which this condition was recorded.
Snehapana, disease of Vatashtila (BPH), Shukumara Kumaraka Ghrita which trial drug of
the study. and incidence, need for study, role of age factor in Vatashtila (BPH).
Objectives of the study: This has explained purpose of the study and objectives
of the study.
171 Summary
Review of literature: This part is described historical review, vyutpatti and
nirukthi of both bastikarma and Sneha, Vatashtila (BPH) The shareera part deals with
both anatomy and physiology related to the Vatashtila (BPH). In the review Basti, the
procedure, types indications and contraindications etc of nirooha, anuvasana etc are
elaborated.
Methodology: This part deals with the administration of Matrabasti and Shamana
Snehapana, ingredients of Shukumara Kumaraka Ghrita and its properties. The study
design, subjective and objective parameters with their gradings and diagnostic criteria,
Observations and Results: This part is dealt in the result section. The
demographic data, response to treatment and overall response are also dealt. Results are
given in the form of tables along with a short description. The improvements in selected
parameters are statistically analyzed and presented in the form of tables and graphs.
Discussion: This part is divided into five sections. Four section entitled- The first
sections discussion on Sharira comparison with prostate gland and disease of Vatashtila
(BPH).The second section discuss about the discussion on analysis of clinical response to
the treatment with logical interpretation study. The third section deals discussion on role
of Sukumara Kumaraka Ghrita in Vatashtila (BPH). Forth section discuss about the
probable mode of action and probable mechanism of Matrabasti and Shamana Snehapana
172 Summary
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Pin :
11. Result :
Well Moderate Mild No
respond response response response
12. Consent : I hereby agree that, I have been fully educated with the disease and
treatment. Hereby satisfied whole heartedly, and accept the medical trial
over me.
Burning micturition
V. FAMILY HISTORY :
Specify the relation No
xx
B. ASTASTHANA PAREEKSHA
1. Nadee :
Dosha
Gati
Poornata
Spandana
Kathinya
2. Mutra :
3. Mala :
4. Jihwa :
5. Shabda :
6. Sparsha :
7. Druk :
8. Aakruthi :
VIII. DASHAVIDHAPAREEKSHA
A. PRAKRITI
V P K VP VK PK SAMA
B. VIKRITI
Dosha Desa
Dushya Kaala
Bala Linga
xxii
C. SAARA
Pravara Madhyama Avara
D. SAMHANANA
Susamhatha Madhyama samhatha Asamhatha
E. PRAMANA
Sama Heena Adhika
F. SATMYA
Ekarasa Sarvarasa
Rookshasaatmya Snigdhasaatmya
G. SATVA
Pravara Madhya Avara
H. AHARASHAKTHI
Abhyavahaara Pravara Madhyama Avara
Jaranasakthi Pravara Madhyama Avara
I. VYAYAMASHAKTHI
Pravara Madhyama Avara
J. VAYAHA
Madhya Vrudha
IX. SROTOPAREEKSHA
Srotas Observed laxana Yes No
Atisrishta
Atibaddha
- Alpaalpa
Mootravaha srotas - Bahala
- Sashoolayukta
Stabdha medhrata
Mutra nirodha
Krichhra and alpa-alpata
Sashabda
Shoolayukta
Purishavaha srotas Atidrava
Atighrathita
Atibahu
Durgandhata
xxiii
B. Cardiovascular system –
C. Respiratory system –
D. Per-abdominal examination –
F. Musculoskleletal system –
X1. NIDANAPAREEKSHA
Sl. Nidana Yes No
Aharaja nidana
1. Rooksha ahara atisevana
2. Rooksha madya atisevana
3. Anupamamsa atisevana
4. Matsya atisevana
5. Adhyashana
6. Ajeerna
xxiv
A. Subjective parameters
BEFORE TREATMENT
AMERICAN UROLOGICAL ASSOCIATION SYMPTOMS INDEX & (I-PSS)
(Questionary for patients)
No. of Pt.’s Less than Less than About half More than Almost
At all 1tim in 5 Half the time the time Half the time Always
1. Over the past month,
how often you had a 0 1 2 3 4 5
sensation of not
emptying your bladder
completely after you
finished urination?
2. Over the past month,
how often you have 0 1 2 3 4 5
had to urinate again less
than 2 hours after you
finished urination?
3. Over the past month,
how often have you 0 1 2 3 4 5
stopped and started
again several times
when you urinated?
xxv
AFTER TREATMENT
No. of Pt.’s Less than Less than About half More than Almost
At all 1tim in 5 Half the time the time Half the time Always
1. Over the past month,
how often you had a 0 1 2 3 4 5
sensation of not
emptying your bladder
completely after you
finished urination?
2. Over the past month,
how often you have 0 1 2 3 4 5
had to urinate again less
than 2 hours after you
finished urination?
xxvi
Present Present
Absent Absent
Present Present
Absent Absent
B. Objective Parameters
BEFORE TREATMENT
AFTER TREATMENT
¾ Feeling of right & left lobe indicates the Ayatatakara astila granthi.
¾ Feeling of firm to hard or hard consistency indicates the Ghana astila granthi.
astila granthi.
xxix
USG findings –
U.S.G. - Report Before treatment fter treatment
Bladder - Trabacular Normal Coarse Normal Coarse
Wall thickness Normal Thickned Normal Thickned
Residual Urine
Prostate Size
Antero - Posterior
Width
Height
Prostate Volume
Kidney Right Left Right Left
Hydronephrosis
Caculi
Size of prostate
Score chart for Weight of prostate
¾ Grade 1 – 20 to 25 gms.
¾ Grade 2 – 25 to 50 gms.
¾ Grade 3 – 50 to 70 gms.
¾ Grade 4 – 75 & above.
xxx
Urine albumin
Urine sugar
Blood investigations –
Sl.No Name of the Test Values
01. Blood urea Mg/dl
02. ESR /1st Hr.
03. Hb% Gm%
3. Total Count
WBC Per cm
RBC Per cm
4. Differential Count
N E B M L
BASTI
PROSTATE NORMAL
ANATOMICALLY
Flow Chart No. 05.
BASTI
Normalisation of Vitiated
Apana Vata
Remission of complaints
Flow chart No. 06.
DIAGRAMMATIC REPRESENTATION OF
PROBABLE MODE OF ACTION OF MATRABASTI THERAPY ON
(BASTI) URINRY BLADDER
BASTI
Stimulus Transmitted
Stimulation of Postganglionic
parasympathetic nerve endings
Release of Acetylcholine