Week 2

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Neurocommunications
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1 of 17 20170403 10:21
1/1
points
1.
The resting membrane potential depends on which of the following
ions:
Potassium ions
Correct
Calcium ions
Un-selected is correct
Chloride ions
Correct
Hydrogen ions
Sodium ions
Correct
2 of 17 20170403 10:21
0/1
points
2.
A neurons membrane potential:
Is carried by electrons that travel through cell

membranes.
Becomes more positive in response to glutamate acting

on glutamate receptors.
This should be selected
Becomes more negative in response to GABA acting at

GABA receptors.
Peaks at a positive potential, about +20 mV, during an

action potential.
Correct
Sits around a negative potential that is about -60 to -70

mV at rest.
Correct
3 of 17 20170403 10:21
0/1
points
3.
Neurotransmitters:
Must bind to receptors in order to have an eect.
Can lead to excitation but not to inhibition of a neuron.
Are very unique substances that are involved in neuronal

communication but not in any other bodily function.
Are packaged in synaptic vesicles.
Correct
Are diverse, consisting of more than 100 dierent

molecules.
Correct
4 of 17 20170403 10:21
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points
4.
Synaptic vesicles:
Contain neurotransmitters.
Correct
Are released more in response to Botox.
Fuse with the cell membrane when calcium ions ood into
the synaptic terminal.
Correct
Are docked at the post-synaptic membrane by SNARE

complexes.
This should not be selected
Are released constitutively from the pre-synaptic neuron.
5 of 17 20170403 10:21
0/1
points
5.
For questions 5-11, please choose the order in which these
events take place. For example, for the rst event, choose
answer "1"; for the second event, choose "2".
Double-check that your answers proceed through 1-7.
---
Neurotransmitter diuses out of a synaptic vesicle into the synaptic

cleft.
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points
6.
The membrane potential of the postsynaptic cell changes.
7 of 17 20170403 10:21
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points
7.
The SNARE pin complex shifts its shape, pushing the vesicular
membrane very close to the cell membrane.
8 of 17 20170403 10:21
1/1
points
8.
Calcium ions ood into the pre-synaptic terminal.
Correct
9 of 17 20170403 10:21
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points
9.
Neurotransmitter binds to a receptor on the post-synaptic
membrane.
Correct
10 of 17 20170403 10:21
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points
10.
Action potential arrives in the pre-synaptic membrane.
Correct
11 of 17 20170403 10:21
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points
11.
Neurotransmitter diuses across the synaptic cleft.
12 of 17 20170403 10:21
0/1
points
12.
Check every event that is prevented by local Botox administration.
Note that more than one of the following choices are correct:
Acetylcholine diuses out of the synaptic vesicle.
Correct
Review the order of steps involved in neuronal
communication through neurotransmitters. Where do
Clostridial toxins like Botox aect this process?
The SNARE pin complex changes shape, leading the

synaptic vesicle to fuse with the cell membrane.
Calcium oods into the motoneuron terminal.
Acetylcholine binds to receptors on the muscle

membrane.
Correct
Review the order of steps involved in neuronal
communication through neurotransmitters. Where do
Clostridial toxins like Botox aect this process?
A synaptic vesicle containing acetylcholine is docked at the

pre-synaptic membrane.
13 of 17 20170403 10:21
1/1
points
13.
Spinal cord strokes are rare but do happen. Which of the following
symptoms could result from a stroke that damages the entire (both
sides) thoracic spinal cord?
A loss of parasympathetic output to the bladder and

colon, resulting in an inability to void urine or feces.
Correct
If you cut the cord at the thoracic cord, lumbar and sacral
functions will be impacted but cervical ones will not be. So
moving legs will be aected but not moving arms. Then
remember that the parasympathetic preganglionic neurons
are split between the brainstem and the sacral cord. The
brainstem ones will be ne and therefore the
parasympathetic innervation of the eye will be ne. But the
parasympathetic preganglionic neurons in the sacral cord
that innervate the colon and bladder will be cut o and they
will not function normally.
Loss of voluntary movement of both arms.
Loss of voluntary movement of both legs.
Correct
If you cut the cord at the thoracic cord, lumbar and sacral
functions will be impacted but cervical ones will not be. So
moving legs will be aected but not moving arms. Then
remember that the parasympathetic preganglionic neurons
are split between the brainstem and the sacral cord. The
brainstem ones will be ne and therefore the
parasympathetic innervation of the eye will be ne. But the
parasympathetic preganglionic neurons in the sacral cord
that innervate the colon and bladder will be cut o and they
14 of 17 20170403 10:21
0.8 / 1
points
14.
Panic attacks could involve which of the following?
High sympathetic tone
Correct
Panic attacks are a highly aroused condition characterized
by high sympathetic tone. Changes from this high emotional
state are likely to alter digestion via eects on the ENS.
A highly aroused emotional state of vigilance
Correct
Panic attacks are a highly aroused condition characterized
by high sympathetic tone. Changes from this high emotional
state are likely to alter digestion via eects on the ENS.
Changes in the activity of the enteric nervous system
High parasympathetic tone
15 of 17 20170403 10:21
0.4 / 1
points
15.
Consider a person who has been spending all their time at home in
a state of profound sadness over the death of a longtime pet.
Concerned friends push this person to go skydiving. Which of the
following are likely to occur as the mourning individual jumps out of
a plane (with an instructor who pulls the rip cord)?
A decrease in peristalsis produced by a less active enteric

nervous system
An enhancement of memory formation
Correct
Sky-diving throws a person into an aroused, sympathetic
state. During high sympathetic state, blood shifts away from
guts to skeletal muscles. And memory formation is
facilitated. Check out this blog post: http://wp.me
/p4e7xm-9B.
A change in emotional state
Correct
Sky-diving throws a person into an aroused, sympathetic
state. During high sympathetic state, blood shifts away from
guts to skeletal muscles. And memory formation is
facilitated. Check out this blog post: http://wp.me
/p4e7xm-9B.
Sympathetic tone, which was low, will increase

dramatically
16 of 17 20170403 10:21
17 of 17 20170403 10:21

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Coursera | Online Courses From Top Universities. ... https://www.coursera.org/learn/neurobiology/exa...

6.2/15 points earned (41%)

You haven't passed yet. You need at least80% to pass.

Is carried by electrons that travel through cell

Becomes more positive in response to glutamate acting

This should be selected

Becomes more negative in response to GABA acting at

This should be selected

Peaks at a positive potential, about +20 mV, during an

Sits around a negative potential that is about -60 to -70

Must bind to receptors in order to have an eect.

This should be selected

Can lead to excitation but not to inhibition of a neuron.

Are very unique substances that are involved in neuronal

Are packaged in synaptic vesicles.

Are diverse, consisting of more than 100 dierent

Are released more in response to Botox.

Are docked at the post-synaptic membrane by SNARE

This should not be selected

Are released constitutively from the pre-synaptic neuron.

Neurotransmitter diuses out of a synaptic vesicle into the synaptic

This should not be selected

This should not be selected

This should be selected

This should not be selected

This should not be selected

Acetylcholine diuses out of the synaptic vesicle.

The SNARE pin complex changes shape, leading the

This should be selected

Calcium oods into the motoneuron terminal.

Acetylcholine binds to receptors on the muscle

A synaptic vesicle containing acetylcholine is docked at the

A loss of parasympathetic output to the bladder and

Loss of voluntary movement of both arms.

Loss of voluntary movement of both legs.

High sympathetic tone

A highly aroused emotional state of vigilance

Changes in the activity of the enteric nervous system

This should be selected

High parasympathetic tone

A decrease in peristalsis produced by a less active enteric

This should be selected

An enhancement of memory formation

A change in emotional state

Sympathetic tone, which was low, will increase

This should be selected

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