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Pathomechanisms offer us a description of the dynamic process through which disease develops
and transforms in the body. When assessing a patient, we generally use pattern identification as
the basis for determining treatment; however, we use pathomechanisms to analyze and explain
the changes that occur over time. Because pattern diagnosis only provides us with a snapshot
picture of the current state of illness, our ability to predict the progression of disease depends
upon our knowledge of pathomechanisms.
A comprehensive understanding of pathomechanisms allows us to practice Chinese medicine
more holistically. It helps us to better anticipate future complications and stay one step ahead of
the disease that we are treating. In addition, it expands our ability to prevent the development of
illness and allows us to live up to the motto that a superior practitioner treats disease before it
arises.
Generally speaking, diagnosis in modern Chinese medicine requires that the practitioner first
differentiate the disease based on TCM disease identification ( bin bng). Each disease
category is divided into patterns, so the condition is then further differentiated by pattern identi-
fication ( bin zhng). This process directs the practitioner to appropriate medicinal ther-
apy and acumoxa treatment. Although this foundation gives us a means of providing effective
treatment, it provides relatively little information on the origin, development, and potential pro-
gression of the condition.
The cause of a disease ( bng yn) is closely related to the pathomechanisms ( bng
j) involved. However, there is an important difference between these two related concepts. The
disease cause explains the origin of the condition, while pathomechanisms describe its dynamic
evolution and progression. In other words, diseases and patterns illustrate the current state of an
illness, the disease cause tells us its origin, and the pathomechanisms tell us everything that hap-
pened in between and everything that we can expect to happen in the future.
The Ni Jng, S Wn (Inner Canon, Plain Questions) states: The hundred diseases change
and arise [when] q and blood are in disharmony. In the Lng Sh (Magic Pivot), we find the
statement: Womens lives have a superabundance of q and an insufficiency of blood. Har-
mony of q and blood is essential for womens health. Because of the close relationship between
blood and q, complex variations and mixed patterns of repletion and vacuity are very common in
the clinic. The primary types of basic disharmony are outlined below:
Pathomechanisms of the Blood
Blood vacuity: Blood vacuity refers to a pathological state of insufficiency of yn-blood that
results in a loss of bloods nourishing and moistening function. It primarily arises from three
mechanisms: 1) Blood may be damaged by profuse bleeding, menstruation, pregnancy, childbirth,
and breast-feeding. Profuse menstrual bleeding, flooding, and great bleeding during pregnancy or
childbirth are particularly significant causes of blood vacuity. 2) Blood vacuity may arise when
q fails to sufficiently form blood. This is generally due to either spleen-stomach vacuity or poor
nourishment. 3) Insufficiency of kidney-essence may cause blood vacuity because essence forms
blood.
When blood is vacuous, the thoroughfare (chng) and controlling (rn) vessels lack fullness.
This may lead to: delayed menstruation, scant menstruation, menstrual block, painful menstrua-
tion, abdominal pain during pregnancy, stirring fetus, habitual miscarriage, atrophied fetus, scant
breast milk, generalized postpartum pain, infertility, and pudendal itching.
Blood Stasis: Blood stasis may arise from cold, heat, vacuity, repletion, injury, surgery, bleed-
ing, and enduring illness. It may lead to a variety of gynecological diseases, which may be
grouped by the causative factors involved:
Blood cold leading to stasis: Cold congeals the blood; it may result from contracting external
cold when the blood chamber is open, i.e., during menstruation or after giving birth. It may
also arise from consumption of raw and cold foods, or from getting soaked in the rain or wading
through water.
Blood heat leading to stasis: Contraction of heat evil or consuming excessive quantities of
acrid, hot foods or yng-assisting medicinals leads to deep-lying heat in the thoroughfare (chng)
and controlling (rn) vessels. This heat scorches the blood and forms stasis.
Q vacuity leading to stasis: Vacuous q lacks the force to move the blood. This causes the
blood to flow slowly, leading to blood stasis.
Q stagnation and blood stasis: Q is the commander of blood; when q moves, the blood
moves. Internal damage by the seven affects inhibits the q dynamic and causes q stagnation,
which in turn gives rise to blood stasis.
When blood stasis is formed, it obstructs the uterus, the uterine vessels, the uterine network
vessels, and the thoroughfare (chng) and controlling (rn) vessels. It may lead to painful men-
struation, menstrual block, headache during menstruation, generalized pain, ectopic pregnancy,
postpartum abdominal pain, infertility, or concretions and conglomerations. Stasis accumulating
over a prolonged time can gradually lead to endometriosis or pelvic inflammatory disease.
Blood Heat: Blood heat refers to heat lying deep within the blood. It causes the blood flow to
accelerate, and in severe cases leads to frenetic movement of hot blood. Blood heat may arise
from constitutional exuberance of yng, from excessive consumption of acrid, hot or yng-
assisting foods, as well as from inappropriate use of yng-assisting and uterus-warming medici-
nals. When deep-lying heat in the thoroughfare (chng) and controlling (rn) vessels leads to
frenetic movement of hot blood, it manifests with profuse menstruation, advanced menstruation,
flooding and spotting, blood ejection or spontaneous external bleeding during menstruation, fetal
spotting, or postpartum heat effusion.
Heat flames upward by nature; if liver depression transforms into heat, it may lead to head-
ache during menstruation, moodiness during menstruation, or advanced menstruation. In patients
with constitutional yn vacuity or damage to yn-blood from menstruation, pregnancy, childbirth,
or breastfeeding, yn vacuity forms internal heat. This heat harasses the thoroughfare (chng) and
controlling (rn) vessels, leading to insecurity of the thoroughfare (chng) and controlling (rn)
vessels; this manifests as advanced menstruation, flooding and spotting, stirring fetus, and persis-
tent flow of the lochia following childbirth.
Blood Cold: When the blood and vessels contract cold, the blood becomes congealed and
moves slowly. Blood cold often results when insufficiency of right q allows contraction of cold
evil to occur during menstruation or after childbirth. It may also arise from constitutional yng
vacuity. Blood cold leads to painful menstruation, delayed menstruation, scant menstruation,
menstrual block, abdominal pain during pregnancy, abdominal pain or generalized pain following
childbirth, or infertility due to uterine cold.
Pathomechanisms of Q
Q vacuity: The impact of q vacuity on womens health varies depending on whether the vacu-
ity primarily affects the lung, spleen, or kidney. In lung q vacuity, insecurity of defensive q in
the outer body leads to common colds during menstruation, postpartum spontaneous sweating, or
postpartum heat effusion. By contrast, spleen q vacuity, center q fall, or kidney q vacuity can
all lead to insecurity of the thoroughfare (chng) and controlling (rn) vessels. These vacuities
may lead to advanced menstruation, profuse menstruation, flooding and spotting, fetal spotting,
uterine prolapse, or loss of breast milk.
Q stagnation: In binding depression of liver q, the free-coursing function of the liver is im-
paired, causing obstruction in the thoroughfare (chng) and controlling (rn) vessels. This gives
rise to menstrual irregularities, menstrual pain, menstrual block, advanced menstruation or men-
struation at irregular intervals, or infertility. When the movement of q is inhibited, the body flu-
ids collect and stagnate. This causes phlegm-damp to form, leading to pathoconditions of puffy
swelling during menstruation, pregnancy swelling, menstrual block, and infertility. Over time, q
stagnation transforms into fire; heat evil may ascend to harass the heart spirit or descend into the
sea of blood to affect the thoroughfare (chng) and controlling (rn) vessels. This causes moodi-
ness during menstruation or after childbirth, as well as visceral agitation. Additionally, when the
q dynamic is inhibited, irregularities in the functions of the liver, stomach, and spleen arise. This
can cause chest oppression with a desire to vomit during menstruation, as well as menstrual pain
or distention and pain in the lesser abdomen, chest, and breasts.
Q counterflow: The lung governs q and depurative downbearing. When lung q ascends
counterflow, it may cause pregnancy cough or pregnancy suspension (a condition of stirring fetus
with distention and fullness in the chest and heart). If liver q invades the stomach and causes
stomach q to counterflow upwards, it may result in vomiting during menstruation or vomiting
during pregnancy.