New QU 8/2017

-: narcotic iv still effective till -1

a- 12 hours b- 24 hours
c- 36 hours d- 72 hours

women with phobia with car which drug is for ttt: -2

Buspirone (Generalized Anxiety Disorder GAD)

Flumazenil with overdose of diazepam with no -3

effect due to -received multiple anesthetic agents in addition to
benzodiazepines or - antidote was small amount or - antidote
taken after 4 hrs

Most potent Statin: Rosuvastatin, Pitavastatin and -4

Atorvastatin

which has fastest action diazepam or lorazepam: -5

lorazepam

yrs man he took pneumococcal with 48 -6

influenza vaccines, which vaccine should take
next
a- influenza b- pneumococcal polysaccharide
c- hepatitis B d- MMR

Lithium and Gentamicin can be measured and -7

curved down after: 8 hrs
Therapeutic Drug Monitoring (TDM)

GMP in KSA means: good manufacturing practices -8

:Simvastatin max dose in geriatric -9
a- 20 mg c- 40mg
d- 60 mg e- 80 mg

: Monophasic OCs means -10

a-Estrogen b-progestron
c-Estrogen + progestrond

: Warfarin antidepressant drug interactions -11

a- Decrease Warfarin metabolism b- increase plasma level

:Athlete's foot player treatment -12

a-oral anticiotic b-oral antifungal
c-topical antifugal d- topical . Oil
NORTE** Antifungal such as Terbinafine (Lamisil); 250 mg/day **
orally once or 2 divided doses for 2-6 weeks

Carbidopa and Levodopa contains mainly -13

? effect
Entacapone which is selectively and reversibly inhibit COMT

:Potassium channel blockers -14

class III antiarrythmia

Interleukin I Inhibitor : Anakinra -15

Ciprofloxacin side effects: seizures -16
Cephalosporins side effects : Allergic reactions (cross- -17
sensitivity) &Hypoprothrombinemia & Mild stomach cramps

:Cyclophosphamide side effects -18

Bladder toxicity (Hemorrhagic_Cystitis)

:Intermittent cough (asthma) treated with -19

Short-acting 2-adrenoceptor Agonists (SABA)

:Toxin that can be used therapeutically -20

a-Botulinum toxin b- x toxin

Vaccines (live attenuated and killed ) how 2 -21

: can be administered
a- at same time b- day after day
c- 2 weaks between them d- monthes between them
Phase 3 and phase 4 in cardiac action -22
potential
Phase 3 (Rapid Repolarization K )
Phase 4 (Resting Membrane Potential; RMP)

: Tyramine not taken with -23

Monoamine Oxidase Inhibitors (MAOIs)

According to KSA cold preparation; drugs not -24

:given to children less than
a-2 years b-4 years
c-6 years d-6 years

:Maximum daily dose of ibuprofen OTC -25

a-800 b-1000
c-1200 d-2000
e-3000
If Q: Maximum dose of Ibuprofen : 3200 **

ttt of hyperkalemia -26

a- kaylexate b- Na
Dose of heparin: 80-100 units /kg -27

Digoxin dose calc should be measure through -28

? or post dose
Through dose , before second dose by half hour-
Therapeutic Drug Monitoring (TDM)-
:types of errors in pharmacy -29
a-adminstratin b-dispensing c-ommission

: Heparin Side effect -30

bleeding complicatins & Hyper sensitivity reactions & Thrombocytopenia &
Osteoporosis has been observed in patients on long-term therapy

:Patient burn hand when cooking -31

a-wash with water for 20-30 min b- put ice c-put vasline

:SE of Lithium -32

headache, dry mouth, polydipsia, polyuria, polyphagia
may include ataxia, slurred speech, coarse tremors, confusion, and convulsions,
arrhythmia, hypotention & Teratogenicity with pregnant
Nurse give pt dose 2 hrs later what is the type -33
of error: wrong time errors - administration error
Fingolimod which used for multiple -34
scelerosis must check up of the following: ECG

Patient with depression and took amitriptine -35

:after days she felt depreesed Dr should
a-shift b-double dose
c- add another antidepressant

Old patient end stage colorectal cancer take 60 -36

mg morphine twice . Suffer pain when he go to
:? bathroom. Add
..-a-Mg b- morphine c

Patient second exposure in h. Pylori and there is 37

risk of resistance he took in first time:
a- amoxicillin + clarithromycin + lanzopazol with doses
b- amoxicillin + bithmuth sulfate + clarithromycin+ amoxicillin
c- Bithmuth sulfate + doxycycline + lanzoprazole
d- Bithmus sulfate+ tetracycline + lanzoprazol

Phenytoin suspension dose : 15ml/day or 5 mL (125 mg/5 mL) three times -38
daily, or one teaspoonful, by mouth 3 times daily. Adjust the dosage to suit
individual requirements, up to a maximum of 25 mL daily

Penicillin allergy caused by : IgE -39

according to the saudia food and drug authority -40
:cough medications are contraindicated in children
A- less than one year B- less than two years
C- less than three years D- less than six years

at what age the tuberculosis vaccines (BCG) -41

:should be given
a- at birth b- 6weeks_2months_4months
c- 2months_4monthd_6months d- 1 year

a man travelled to Africa and while he was there-42

he got ameoba and started metronidazole 500mg
three times daily after 7 days he still have
? symptoms .what medication can be added
a- vancomycin b- erythromycin
c- diloxanide

a child is taking high dose amoxicillin (99mg/kg) -43

for otitis media came to the clinic for pneumonia
:and infuenza vaccine
a) cancel the vaccines b) proceed to give the vaccines
c) delay the vaccines for one year

?MMR vaccine is given at what age -44

first dose 12months and second dose 4years

the cause of diphtheria: corynebacteriam -45

:Vit c used for -46
a-Coloring agent b-Preservative
c-Tasting agent
Alndronate dose per week: 70mg once aweak =10 mg -47
daily
Antidot for atropin? : Physostigmine -48
Role of scientific office in pharmaceutical -49
:company
A pharmaceutical establishment that provides scientific, technical and
marketing information on pharmaceutical preparations throughout the
.Kingdom
:Nilotinib -50
Tyrosine Kinase Inhibitor use as
chronic myelogenous leukemia (CML)
gastrointestinal stromal tumors (GISTs)

years .playing sport . Dry cough , Weezing , 40 -51

: chest tightness
a- Laba b- SABA c- Inhaled corticosteroid d-Loncet

Dr ask pharmacist about interaction between -52

warfarin and heparin? Chosse ipnr after how
:many days and the test result

Prescription of tramadol written 2days ago in -53

Riyad and you are a pharmacist in dammam what
will you do
a- don't dispense b- call doctor to change drug
c- dispense
d- fill 3 days

:Mechanism of action of sitagliptin -54

dipeptyl peptidase no. 4 inhibitor (DPP IV Inhibitor)

adanafil effect on pt using nitrate with -55

diabetes is: non pharmacological treatment

most common dispensed in otc : Multi Vitamins -56

drug disponsed to patient and the nurse -57
found that there was another dose at the patient
: room so what should she do
a- return the dose to the pharmacy
b- keep it to the next dose
c- throw it away

one of the OTC : Ibuprofen -58

: Misoprostol is used for -59
a- prevent ulcer b- prevent and treat gastric ulcer
c- treatment of ulcer

A woman with seizure is on valproic acid shes -60

?planning to get pregnant what is the best choice
a- continue on valproic acid b- stop valproic acid
c- change to levetiracetam

which of these laxatives have the lowest onset -61

:of action
a- milk of magnesia b- glycerin
c- Biscodyl d- psyllium

A patient with a gastric ulcer caused by -62

h.pylori and started on triple therapy
( clarithromy, metronidazole ,ppi)but his
symptoms not improved because of bacterial
: resistant
a- (clarithromycin, amoxicillin,ppi)
b- (bismuth, tetracycline, metronidazole ,ppi)
c- (bismuth, doxycycline, metronidazole,ppi)

at what time 99% of the drug will be cleared -63

:from the plasma
a- 4.5 t half b- 6.6 t half
c- 7.4 t half

What is the meaning of pregnancy category -64

:B
Animal reproduction studies have failed to demonstrate a risk to the fetus
.and there are no adequate and well-controlled studies in pregnant women

: validity of Pharmacy permit -65

a-1 year b-3 years
c-5 years d-10

: MMR vaccine is given at what age -66

first dose 12months and second dose 4years

when we should stop plavix before cardiac -67

: surgery
Days 5-7

: in which muscle we give vaccine for infants -68

The vastus lateralis muscle in the anterolateral thigh

: which of this lowest potency laxative- -69

a- glycrine b- magnesium milk
c- bisacodyl

Pharmacy regulation & guidlines is comming -70

:from
a-MOH b-SPA
c-sFda d-scfhs
GPhC)( General Pharmaceutical Council
71-therapeutic equivalent dose of omeprazole 20
is: a- cimetidin 800 mg b- esomeprazole 40 mg
c- ranitidine 300 mg d- pantaprazole 40 mg

72-dose of ferrous sulfate: 300 B.I.D

73- which NSAID has more enterogenic effect

a- Piroxicam b- Naproxen c- Dicofenac d- Ibuprofen

74- physician prescribe Amoxicillin if you don't

have the brand what you will do:
a- Will you give the generic b- send him an other pharmacy
c- tell him you dont have the medicine
75- child receive high dose Amoxicillin for otitis
and he has-appointment for vaccine what we do
shall we postponed the vaccination ?: NO
76- child receive short acting b agonist without
improvement then he develop cough with
wheeping what is the treatment: a- Amoxicillin
b- azithromycin c- steroid

77- pt was treated with Fluoxetine without

improvement after how many weeks: you shift him to
anther group
78- Warfarin and heparin was prescribed to pt in
hospital how long he will take the heparin and how
much the INR :
Take heparin for 2 days with warfarin then stop heparin , warfarin biological t/2
after 48 hours

79- Total knee replacement which anticoagulation

he should continue:
a- asprin b-heparin c-Clopidogril

80- Pseudoefedrine is:

a- antiallergic b- decongestant

81-20 mg omeprazol equal to which doses of

pantoprazol or ranitidin in the H.Pylori treatment:
pantaprazole 40 mg
82- Pt with Prostate hyperplasia and dysuria what
medication u will give :

83-35years BMI35 , (Oral contaceptive)?:

Only progesterone pill

84- Baby with immunedeficiency syndrome took

immunoglobulin which vaccines is C.I:
a- mmr b- rubella c- meningitis d- rotavirus (RV)

85- Baby with fever & tugging ear. Doctor exclude

bacterial infection : (amoxicillin with different doses + antiviral i do
not remember)

86- Calculate cr.cl age 40 &weight 80 &sr.cr=

0.5Result mg /ml
For male
- For female = CrCl of male x 0.85

87- what is the treatment of keto acidosis :

-Correction of fluid loss with intravenous fluids

-Correction of hyperglycemia with insulin

-Correction of electrolyte disturbances, particularly potassium loss

-Correction of acid-base balance

-Treatment of concurrent infection, if present

88- what should be monitored when giving patient

lithium therapy:

89- Liraglutide MOA:

Liraglutide (NN2211) is a derivative of human incretin (metabolic hormone) glucagon-like
peptide-1 (GLP-1) that is used as a long-acting glucagon-like peptide-1 receptor agonist,
binding to the same receptors as does the endogenous metabolic hormone GLP-1 that
stimulates insulin secretion.
90- child weight 16 kg and length 92 cm calculate
the body surface area ?

so BSA(m)= SQRT (92x16)/3600

= SQRT (.48555)

=.69681 m

91- Anti metabolite cause bone marrow

suppression: Azathioprine or Methotrexate

92- Relation between autism and vaccine:

Relation between autism and MMR vaccine ?? No relation
Relation between autism and thimerosal vaccine ?? relation
93- Urine incontinence drugs for urge conditions?:
-Anticholinergic medications
-Mirabegron (Myrbetriq)
-Ona botulinum toxin type A (Botox)
94- Body mass index and body surface area
calculation:

95- Duration of using domperidon 68 hrs

96- Duration of esomeprazole in gastroesophagial

disease: up to 24 hrs
97- Drug and dose of Infant with mild fever:
paracetamol 1 gm per day
98- Antibiotic cause hyperkalemia:
trimethoprim - sulfamethoxazole
99-Selective estrogen modulator:
tamoxifen

100- Masking acidic taste of syrup use which

flavor: strong base anion exchange resins
(grape, maple, raspberry, and wild cherry- Menthol )

101- Dose of enxaparine in male with DVT1.5 or1 rout

IV or IM: IV SC
102- organophosphorus toxicity removed by: Gastric
lavage

103- Reduce gastric side effect of metoformine

administer metoformine. .......?:
biggest complaint people have about Metformin is that it causes gas and
diarrhea. This can often be reduced by increasing the dose gradually

104- Dispense a prescription of diazepam for:

a- 7days b- 14 days c- 30 days

105-A man with hypertension and myocardial

infarction his medications are metoprolol and
nitroglycerin for his MI he present to the clinic with
erectile dysfunction what medication is the most
appropriate for his erectile dysfunction:
a- sildenafil b- avanafil c- no pharmacological treatment
106- Antiarrhythmic drug cause iodine
hypothyroidism : amiodarone
107- Metformin avoiding its side effect of N, V:
Metformin nausea and vomiting may be asign of lactic acidosis.And treatment is :
treating Lactic acidosis sometimes represents a medical emergency. Increasing
oxygen to the tissues and giving IV fluids are often used to reduce lactic acid
levels. Electrolyte-replacement sports drinks such as Gatorade help with
hydration, but water is usually best.

108- Pt taking prazocin , want to give him

tadalafil , want the time duration bet them: 4 hours

109- patient is on Omeprazole and it's expired what

you advice her?:
a- she can take it if it was stored properly
b- buy a new one

110- Anti hypertension drug safe in pregnant?:

labetalol
111- pt take morphen and we want replace by
Fentanyl ?:

Fentanyl is 50 to 100 times more potent than morphine (80)

112- Removing a drug from formulary:

pharmacy therapeutic committee

113- Anti hypertensive drug... can affect fetal
growth:

a- Amlodipine b- hydrochlorothiazide c- lisinopril

114- Diuretic side effects are ototoxicity and
deafness:

a- frusemide b- triamterene c- hydrochlorothiazide

115- Food that should be avoided when taking
amiodarone:

grape fruit
116- The meaning of compassionate drug use:

use a drug that not approved yet (new unapproved drug)

117- Overlapping of clexane with warfarin:

At least 5 days

118- Voriconazole dose is adjusted in hepatic impairment:

100 mg/ twice daily

119- Chlild with otitis media with QT prolongation ,
which abx is CI: azithromycin
120- Mechanism of action of (aliskiren):

Aliskiren (trade names Tekturna and Rasilez) is the first in a class of drugs
called direct renin inhibitors. It is used for essential (primary) hypertension.
121- Lamotrigen we start with small doses then
increase(reson):

to prevent develop of serious Rash.

122- When Women start folic acid :

-One month before Pregnant

123-Dose of enoxaparin in knee replacement:

30 mg SC q12hr; initiate therapy 12-24 hr postoperatively and continued for 10

days or up to 35 days postoperatively or until risk of DVT has been significantly
reduced or patient is on anticoagulant therapy

124- terazosin Mechanism of action :

selective alpha-1 antagonist

126- maximum dose of Phyntoin: 300mg/d

127- what enzyme we used for acute leukemia :

L-Asparaginase enzyme
128-Cetirizine MOA-: H1 blocker

129- MMR is : mixture of live attenuated viruses

130- Pilocarpine : medication used to treat open angle glaucoma

131- Sevelamer: decreases serum uric acid concentration .

132- bone marrow suppression :
a- Vincristine b-Ergot c-L-aspiregase d- doxorubicin

133- Vincristine adminstration:

by minibag (IV push) or infusion (IV)

136- simvastatin daily dose for pt

hypercholestrolemia:
a- 20 b-40 c-60 d- 80

132- zolpidem maximum dose:

a- 5 mg/d b-10 mg/d c-15 mg/d d-20 mg/d

134- labetalol M.O.A:

135- Montelukast MOA :

Leukotriene antagonists
*NB*
used for the maintenance treatment of asthma and to relieve symptoms of
seasonal allergies. It is usually administered orally.

136- dosage form preferred for children : Oral

137- Biosimilar means:

is a biologic medical product which is almost an identical copy of an original
product that is manufactured by a different company. [1] Biosimilars are
officially approved versions of original "innovator" products, and can be
manufactured when the original product's patent expires.

138- Proton Pump Inhibitors MOA:

inhibitors act by irreversibly blocking the hydrogen/potassium adenosine
triphosphatase enzyme system (Inhibitors of the H+/K+-ATPase proton pump)

139- Example of drug disease interaction:

pioglitazone and heart failure

140- speed of response of receptors ( receptor

response in milliseconds and other receptor
response in seconds :
a- voltage gated receptors and ligand gated receptors
b- voltage gated receptors and G _ protein receptors
c-ligand gated receptors and G _ protein receptors
d- ...........................................

141- Which solution is isotonic

a- dextrose 5% b- saline 3%
c- ringer solution d- ....................

142- case is taking doxycycline for acne and

doctor prescribe adapalene for topical use and
doxycycline for systemic use and he suffer from
heartburn you advised him to :
a- take omeprazole with doxycycline
b- stop adapalene
c- apply adapalene as thin layer
d-