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Most potential bioterrorism agents are natural substances or microorganisms that normally cause
a small number of deaths each year and/or during periodic outbreaks. They enter the body
primarily by being inhaled into the lungs, ingested, through breaks in the skin, or through contact
with the mucous membranes of the eyes and nose.
Agents may be genetically altered by those seeking to use them as a weapon. They may be
concentrated, made easier to disperse (aerosolized), made more likely to infect, and/or made
more resistant to treatment. Some agents cause infections that can be passed easily from person-
to-person and would need to be quickly contained, while others, such as anthrax, typically affect
only the person exposed but can be deadly without prompt treatment.
The Centers for Disease Control and Prevention (CDC) identifies potential bioterrorism agents
according to the risk they pose to the public. The table below gives examples of select agents and
toxins. For more information, see the CDC Select Agents and Toxins List.
For more specific information on agents of bioterrorism and emergency preparedness plans the
U.S. government has in place in the event of another bioterrorist attack, visit the CDC's
bioterrorism web site.
In addition to biological agents, chemical and radioactive agents may also be used as weapons of
terrorism. An example of the use of chemical agents by a terrorist group occurred in 1994 and
1995 when the Aum Shinrikyo cult released the nerve gas sarin into the air in Japan, resulting in
19 deaths and thousands of people injured. An example of a radioactive agent is polonium 210,
which in 2006 was the cause of death of Russian dissident, Alexander Litvinenko. For more on
these agents, see the CDC webpage Preparing for and Responding to Specific Hazards.