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forward with recalling Senator John McCain on the grounds of Physical or mental lack of fitness
So Mr. McCain can focus attention on his medical treatment for GBM.
1 Globlastoma (GBM) is terminal enough and the prognosis of his symptoms are dire conditions-
enough for the people in AZ to demand he step down -, retire, immediately and take care of his
health.
2 Arizona's governor must demand this, and begin the process to hold a special election.to seat
Glioblastomas are usually highly malignant, a large number of tumor cells are metastasizing
within the CNS "Metastasis of intracranial GBM to the spinal cord has been described with
increasing frequency in recent years. Autopsy series suggest that approximately 25% of patients
Case 1
A 51-year-old right handed male presented with headache, behavioral changes, and
person with impairment of recent memory. He was unable to name objects and also had mild
slurring of speech. Magnetic Resonance Imaging (MRI) revealed a solid and cystic lesion in the
(GBM is nourished by an ample blood supply. Dead cells may also be seen, especially toward
the center of the tumor. Because these tumors come from normal brain cells, it is easy for them
FIGURE 2A
There are two types of glioblastomas:
Primary, GBM : tend to form and make their presence known quickly. This is the most
Secondary: These tumors have a longer, somewhat slower growth history, but still are very
aggressive. They may begin as lower-grade tumors which eventually become higher grade. They
tend to be found in people 45 and younger, and represent about 10% of glioblastomas.
Glioblastoma has an unfavorable prognosis mainly due to its high propensity for tumor
recurrence. It has been suggested that GBM recurrence is inevitable after a median survival time
months with maximal treatment, but those without any intervention die soon after diagnosis.
Gliolastoma prognosis gives him around 2 years. It is not clear what stage he is in. however are
what he can expected without undergoing radical treatment that will have a huge impact on his
mental capacity as well as his physical state during the treatment up to the last 3 months of his
Symptoms related Brain Cancer include increased intracranial pressure (headache and
swallowing) he won't feel much pain due to the pain sensory portion of the brain is not affected.
Fall risks along with increasing weakness on the affected side difficulty walking Urinary/bowel
incontinence. His cognitive thought process will diminish rapidly. Confusion and memory loss
and more difficulty holding a conversation. Saying things that ill border on being senile "
Increasingly tired, more easily "wiped out" after simple activities or outings along with
Constipation and a frequent need for stool softeners and progressing to needing enema's due to
Cognitive/Personality/Speech
He will say things that are impossible to make out or things that don't make sense
Physical
Taking only minimal amounts of food (a spoonful or two, here and there); some, however,
May have no response or only nonverbal communication (eg, winks, waves, or nods)
and End Stage the above symptoms will increase. along with Usually minimal or no urine output
Reaches a point of unresponsive sleep (coma), which can last from 1 hour to most of the day
No longer any involuntary movement during sleep (no fidgets or eye movements)
Mouth may slacken and eyes may remain partially open during sleep, as voluntary muscle
control is lost
Resources
1. Davis FG, Freels S, Grutsch J, Barlas S, Brem S. Survival rates in patients with primary
malignant brain tumors stratified by patient age and tumor histological type: An analysis
Neurosurg. 1998;88:110.
2. McLendon RE, Halperin EC. Is the long-term survival of patients with intracranial
3 Erlich SS, Davis RL. Spinal subarachnoid metastasis from primary intracranial glioblastoma
1991;35:37780. [PubMed]